Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(226 productos)
- HSP(179 productos)
- Integrin(253 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(124 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3872 productos de "Ciclo celular / Checkpoint"
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PfDHODH-IN-1
CAS:PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.Fórmula:C14H11F3N2O2Pureza:99.87%Forma y color:SolidPeso molecular:296.24Ref: TM-T12438
1mg52,00€5mg101,00€10mg152,00€25mg295,00€50mg447,00€100mg658,00€200mg888,00€1mL*10mM (DMSO)92,00€GAK inhibitor 49 hydrochloride
Potent GAK inhibitor 49 hydrochloride: ATP-competitive, highly selective, Ki=0.54 nM, IC50=56 nM, binds to RIPK2.Fórmula:C20H23ClN2O5Forma y color:SolidPeso molecular:406.86Tirapazamine
CAS:Tirapazamine (Win59075) triggers apoptosis in hypoxic cells by damaging DNA and enhances effects of radiation and cisplatin.Fórmula:C7H6N4O2Pureza:96.65% - 99.87%Forma y color:Orange-Red Crystalline PowderPeso molecular:178.15LDN-192960 hydrochloride
CAS:LDN-192960 hydrochloride is an inhibitor of Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) and Haspin with IC50s of 48 nM and 10 nM, respectively.Fórmula:C18H22Cl2N2O2SPureza:98%Forma y color:SolidPeso molecular:401.35Levofloxacin hydrochloride
CAS:Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.Fórmula:C18H21ClFN3O4Pureza:99.78% - 99.98%Forma y color:SolidPeso molecular:397.8Lurbinectedin
CAS:Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.Fórmula:C41H44N4O10SPureza:98.11%Forma y color:SolidPeso molecular:784.87M2N12
CAS:M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.Fórmula:C20H16ClN5O2Pureza:98.01%Forma y color:SolidPeso molecular:393.83Ref: TM-T11929
1mg84,00€5mg152,00€10mg236,00€25mg447,00€50mg670,00€100mg982,00€1mL*10mM (DMSO)167,00€CRT0066854
CAS:CRT-0066854 is a PKCι and PKCζ inhibitor. CRT0066854 was able to restore polarized morphogenesis in the dysplastic H-Ras spheroids.Fórmula:C24H25N5SForma y color:SolidPeso molecular:415.55Mps1-IN-3 hydrochloride
Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.Fórmula:C26H32ClN7O4SForma y color:SolidPeso molecular:574.09Tipiracil
CAS:Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.Fórmula:C9H11ClN4O2Pureza:99.815%Forma y color:SolidPeso molecular:242.66Vidofludimus
CAS:Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).Fórmula:C20H18FNO4Pureza:98.33% - 99.58%Forma y color:SolidPeso molecular:355.36GPRP acetate (67869-62-9 free base)
CAS:GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.
Fórmula:C20H35N7O7Pureza:>99.99%Forma y color:SolidPeso molecular:485.53BS-181 dihydrochloride
CAS:BS-181 dihydrochloride: Potent CDK7 inhibitor (IC50: 21 nM), less effective on CDK2/5/9, no impact on CDK1/4/6, halts cancer cell growth, triggers apoptosis.Fórmula:C22H34Cl2N6Forma y color:SolidPeso molecular:453.46Cetraxate hydrochloride
CAS:Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.Fórmula:C17H24ClNO4Pureza:99.75%Forma y color:SolidPeso molecular:341.83WNK463
CAS:WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).Fórmula:C21H24F3N7O2Pureza:>99.99% - ≥95%Forma y color:SolidPeso molecular:463.46TH588
CAS:TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.Fórmula:C13H12Cl2N4Pureza:96.05% - 99.82%Forma y color:SolidPeso molecular:295.171,4-Anthraquinone
CAS:1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.Fórmula:C14H8O2Pureza:95.96% - 97.01%Forma y color:Orange Brown SolidPeso molecular:208.21CDK9-IN-30
CAS:CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.Fórmula:C16H20FNO3Pureza:99.75%Forma y color:SolidPeso molecular:293.33Ref: TM-T9632
1mg56,00€5mg119,00€10mg187,00€25mg316,00€50mg472,00€100mg658,00€500mg1.378,00€1mL*10mM (DMSO)114,00€Temozolomide Acid
CAS:TMZA, a TMZ metabolite, shows in vitro anticancer effects. TMZ, an oral alkylator, treats GBM and astrocytomas.Fórmula:C6H5N5O3Pureza:99.28%Forma y color:SolidPeso molecular:195.14PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS:CRT0066101 dihydrochloride is an inhibitor of PKD.Fórmula:C18H21Cl3N4OPureza:99.5%Forma y color:SolidPeso molecular:415.75
