Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(226 productos)
- HSP(179 productos)
- Integrin(253 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(124 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3872 productos de "Ciclo celular / Checkpoint"
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DMT-2′Fluoro-dU Phosphoramidite
CAS:DMT-2′Fluoro-dU Phosphoramidite (2'-F-dU Phosphoramidite) can be used to modify nucleosides.Fórmula:C39H46FN4O8PPureza:99.5%Forma y color:SolidPeso molecular:748.78MLN0905
CAS:MLN0905 (PLK1 Inhibitor) is an effective PLK1 inhibitor(IC50=2 nM).Fórmula:C24H25F3N6SPureza:98% - 99.92%Forma y color:SolidPeso molecular:486.56Zoliflodacin
CAS:Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.Fórmula:C22H22FN5O7Pureza:99.82% - 99.93%Forma y color:SolidPeso molecular:487.44Ref: TM-TQ0063
1mg105,00€5mg245,00€10mg389,00€25mg645,00€50mg888,00€100mg1.234,00€500mg2.457,00€1mL*10mM (DMSO)264,00€TH588 hydrochloride
CAS:TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.Fórmula:C13H13Cl3N4Forma y color:SolidPeso molecular:331.63Ibezapolstat
CAS:Ibezapolstat (ACX-362E) is an antibiotic with antibacterial activity that inhibits Clostridium difficile.Fórmula:C18H20Cl2N6O2Pureza:98% - 99.429%Forma y color:SolidPeso molecular:423.3Ref: TM-T10243
1mg54,00€5mg114,00€10mg185,00€25mg369,00€50mg594,00€100mg952,00€1mL*10mM (DMSO)127,00€5'-Deoxy-5-fluorocytidine
CAS:5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.Fórmula:C9H12FN3O4Pureza:99.67%Forma y color:White SolidPeso molecular:245.21IMM-H007
CAS:IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFórmula:C22H23N5O8Pureza:97.73%Forma y color:SolidPeso molecular:485.45Ref: TM-T9010
1mg40,00€5mg96,00€10mg135,00€25mg226,00€50mg320,00€100mg434,00€200mg602,00€1mL*10mM (DMSO)131,00€Mitonafide
CAS:Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.
Fórmula:C16H15N3O4Pureza:99.89%Forma y color:SolidPeso molecular:313.31Ref: TM-T25817
1mg35,00€2mg48,00€5mg70,00€10mg96,00€25mg188,00€50mg311,00€100mg510,00€200mg728,00€500mg1.093,00€CHR-6494 TFA
CAS:CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.Fórmula:C18H17F3N6O2Pureza:99.50%Forma y color:SolidPeso molecular:406.36Ref: TM-T9521
1mg60,00€5mg122,00€10mg190,00€25mg318,00€50mg452,00€100mg627,00€200mg845,00€1mL*10mM (DMSO)142,00€Apcin-A
CAS:Apcin-A is an anaphase-promoting complex (APC) inhibitor.Fórmula:C10H14Cl3N5O2Forma y color:SolidPeso molecular:342.61Palbociclib dihydrochloride
Palbociclib, oral CDK4/6 inhibitor (IC50: 11/16 nM), targets HR+/HER2- breast cancer and hepatocellular carcinoma.Fórmula:C24H31Cl2N7O2Forma y color:SolidPeso molecular:520.45Sarecycline free base
CAS:Sarecycline free base (P005672) is a tetracycline-derived, narrow-spectrum antibiotic.Fórmula:C24H29N3O8Pureza:98%Forma y color:SolidPeso molecular:487.5AT7519 TFA
CAS:AT7519 inhibits CDK1-6 kinases; IC50 ranges 0.018-0.66 μM.Fórmula:C18H18Cl2F3N5O4Forma y color:SolidPeso molecular:496.27Tiazofurin
CAS:Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.Fórmula:C9H12N2O5SPureza:99.91%Forma y color:SolidPeso molecular:260.27SBC-115076
CAS:SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.Fórmula:C31H33N3O5Pureza:97.07% - 99.89%Forma y color:SolidPeso molecular:527.61Ref: TM-T2626
1mg38,00€2mg50,00€5mg80,00€10mg94,00€25mg172,00€50mg309,00€100mg477,00€500mg1.063,00€1mL*10mM (DMSO)87,00€GSK2850163 hydrochloride
CAS:GSK2850163 hydrochloride is a novel IRE1α inhibitor with IC50 of 20 nM for kinase and 200 nM for RNA enzyme.Fórmula:C24H30Cl3N3OForma y color:SolidPeso molecular:482.87Phthalazinone pyrazole
CAS:Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Fórmula:C18H15N5OPureza:97.03%Forma y color:SolidPeso molecular:317.342-Aminofluorene
CAS:2-Aminofluorene (2-Fluorenamine) is a biochemical.Fórmula:C13H11NPureza:99.9%Forma y color:Light Yellow CrystallinePeso molecular:181.23STAMBP-IN-1
CAS:STAMBP-IN-1 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release afterFórmula:C27H28N4O4SPureza:99.64%Forma y color:SolidPeso molecular:504.6Ref: TM-T8706
1mg67,00€5mg152,00€10mg236,00€25mg507,00€50mg730,00€100mg1.018,00€1mL*10mM (DMSO)192,00€RNase L-IN-2
CAS:RNase L-IN-2 activates RNase L at 22 uM, has antiviral effects on various RNA viruses, non-toxic at effective levels.Fórmula:C16H14N2O2SPureza:98.81%Forma y color:SolidPeso molecular:298.36Ref: TM-T8591
1mg120,00€5mg264,00€10mg395,00€25mg627,00€50mg890,00€100mg1.198,00€200mg1.603,00€1mL*10mM (DMSO)243,00€
