Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(179 productos)
- Integrin(262 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(126 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3888 productos de "Ciclo celular / Checkpoint"
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Levomefolate calcium
CAS:Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements.Fórmula:C20H23CaN7O6Pureza:97.35%Forma y color:Off-White To Pale Yellow SolidPeso molecular:497.52Hydroxyfasudil
CAS:Hydroxyfasudil (Hydroxy-Fasudil) is a ROCK inhibitor(IC50s of 0.73 and 0.72 μM for ROCK1 and ROCK2, respectively).Fórmula:C14H17N3O3SPureza:98.13%Forma y color:SolidPeso molecular:307.37SBC-110736
CAS:SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitorFórmula:C26H27N3O2Pureza:99.44%Forma y color:SolidPeso molecular:413.516-Thio-2'-Deoxyguanosine
CAS:6-Thio-2'-Deoxyguanosine (β-TGdR) is a nucleoside analog and telomerase substrate.Fórmula:C10H13N5O3SPureza:97.52%Forma y color:SolidPeso molecular:283.31HQ461
CAS:HQ461, a molecular glue, boosts CDK12-DDB1 binding, lowers cyclin K, impedes CDK12 phosphorylation, hinders DNA repair genes, and induces cell death.Fórmula:C15H15N5OS2Pureza:98.11%Forma y color:SolidPeso molecular:345.44Ref: TM-T9849
1mg43,00€2mg56,00€5mg93,00€10mg144,00€25mg319,00€50mg537,00€100mg767,00€500mg1.558,00€1mL*10mM (DMSO)90,00€RI-2
CAS:RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.Fórmula:C21H18Cl2N2O4Pureza:99.63% - 99.86%Forma y color:SolidPeso molecular:433.28Ref: TM-T2628
1mg70,00€2mg92,00€5mg152,00€10mg266,00€25mg413,00€50mg605,00€100mg863,00€1mL*10mM (DMSO)166,00€SL327
CAS:SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/0.22 μM; able to transport through the blood-brain barrier.Fórmula:C16H12F3N3SPureza:97.98% - >99.99%Forma y color:SolidPeso molecular:335.35ML364
CAS:ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for the research of breast cancer.Fórmula:C24H18F3N3O3S2Pureza:99.35% - >99.99%Forma y color:SolidPeso molecular:517.54LY3143921
CAS:LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].Fórmula:C16H12FN5OForma y color:SolidPeso molecular:309.3Carotegrast methyl
CAS:Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.Fórmula:C28H26Cl2N4O5Pureza:99.26% - 99.72%Forma y color:SolidPeso molecular:569.44BSJ-4-116
CAS:BSJ-4-116: potent, selective CDK12 PROTAC, IC50 = 6 nM; downregulates DDR genes, induces premature transcription termination.Fórmula:C40H49ClN8O8SPureza:99.09%Forma y color:SolidPeso molecular:837.38PF-06873600
CAS:PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.Fórmula:C20H27F2N5O4SPureza:98.77% - 99.55%Forma y color:SolidPeso molecular:471.52Ref: TM-T8463
1mg54,00€5mg114,00€10mg178,00€25mg334,00€50mg557,00€100mg888,00€200mg1.198,00€1mL*10mM (DMSO)118,00€2'-Deoxy-2'-fluorocytidine
CAS:2'-Deoxy-2'-fluorocytidine is an nucleoside analog and inhibits of Crimean-Congo hemorrhagic fever virus (CCHFV) replication potently.Fórmula:C9H12FN3O4Pureza:99.90%Forma y color:White Or Almost White Crystalline PowderPeso molecular:245.21Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Forma y color:SolidPeso molecular:938.71CHR-6494
CAS:CHR-6494 is a haspin inhibitor that inhibits histone H3T3 phosphorylation (IC50: 2 nM).Fórmula:C16H16N6Pureza:98.78%Forma y color:SolidPeso molecular:292.34Ref: TM-T14959
5mg54,00€10mg82,00€25mg145,00€50mg259,00€100mg442,00€200mg643,00€1mL*10mM (DMSO)60,00€USP7/USP47 inhibitor
CAS:USP7/USP47 inhibitor (USP7/47 inhibitor-1) is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM,Fórmula:C18H11Cl2N3O3S3Pureza:98.5% - 98.71%Forma y color:SolidPeso molecular:484.4Ref: TM-T4338
1mg40,00€5mg96,00€10mg152,00€25mg268,00€50mg429,00€100mg703,00€200mg954,00€1mL*10mM (DMSO)94,00€XL177A
CAS:XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.Fórmula:C48H57ClN8O5Pureza:98.75%Forma y color:SolidPeso molecular:861.47APY29
CAS:APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.Fórmula:C17H16N8Pureza:96.51% - 98.46%Forma y color:SolidPeso molecular:332.36Ref: TM-T3654
2mg40,00€5mg62,00€10mg90,00€25mg167,00€50mg285,00€100mg515,00€500mg1.071,00€1mL*10mM (DMSO)67,00€Quarfloxin
CAS:Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.Fórmula:C35H33FN6O3Pureza:99.77%Forma y color:SolidPeso molecular:604.67Ref: TM-T16703
1mg71,00€2mg92,00€5mg152,00€10mg236,00€25mg380,00€50mg530,00€100mg708,00€1mL*10mM (DMSO)212,00€SAR407899
CAS:SAR407899 is Rho kinase inhibitor potently inhibits endothelin-1-induced constriction of renal resistance arteries.Fórmula:C14H16N2O2Pureza:99.42%Forma y color:SolidPeso molecular:244.29Ref: TM-T7391
2mg34,00€5mg50,00€10mg75,00€25mg128,00€50mg200,00€100mg319,00€200mg474,00€1mL*10mM (DMSO)55,00€
