CymitQuimica logo
Ciclo celular / Checkpoint

Ciclo celular / Checkpoint

Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.

Subcategorías de "Ciclo celular / Checkpoint"

Mostrar 10 subcategorías más

Se han encontrado 3756 productos de "Ciclo celular / Checkpoint"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
productos por página.
  • LNA-GDP
    Targetmol
    + Info

    LNA-GDP

    CAS:
    LNA-GDP is a nucleotide analog utilized in the synthesis of oligonucleotides.
    Fórmula:C11H15N5O11P2
    Forma y color:Solid
    Peso molecular:455.21

    Ref: TM-TSW-00961

  • 5-Methylcytosine hydrochloride
    Targetmol
    + Info

    5-Methylcytosine hydrochloride

    CAS:
    5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.
    Fórmula:C5H8ClN3O
    Forma y color:Solid
    Peso molecular:161.59

    Ref: TM-T201054

  • LIMK-IN-2
    Targetmol
    + Info

    LIMK-IN-2

    CAS:
    <p>LIMK-IN-2 (Compound 52), an LIMK inhibitor, has demonstrated potential anti-angiogenic activity by suppressing the cell migration of osteosarcoma and cervical cancer cells [1].</p>
    Fórmula:C28H27N5O2
    Forma y color:Solid
    Peso molecular:465.55

    Ref: TM-T86811

  • D-G23
    Targetmol
    + Info

    D-G23

    CAS:
    <p>D-G23 is a selective RAD52 inhibitor. It disrupts RAD52-mediated DNA repair pathways and suppresses the growth of cancer cells deficient in BRCA1 and BRCA2. D-G23 shows promise for research into homologous recombination-related cancers caused by BRCA1/2 mutations, such as hereditary breast and ovarian cancers.</p>
    Fórmula:C19H22N4O3
    Forma y color:Solid
    Peso molecular:354.403

    Ref: TM-T206763

  • Logo de CymitQuimica
    Targetmol
    + Info

    Antibacterial agent 110

    Compound 4e, an antibacterial against P. aeruginosa, disrupts cell membranes (MIC: 1 μg/ml).
    Fórmula:C22H21N5O4S
    Forma y color:Solid
    Peso molecular:451.5

    Ref: TM-T62740

  • LIMK1 inhibitor 2
    Targetmol
    + Info

    LIMK1 inhibitor 2

    CAS:
    LIMK1 inhibitor 2 (compound 41) is a LIMK1 inhibitor with an IC50 value of 9 μM.
    Fórmula:C10H11N3OS
    Forma y color:Solid
    Peso molecular:221.279

    Ref: TM-T204765

  • Pseudouridine 5'-OTBDPS
    Targetmol
    + Info

    Pseudouridine 5'-OTBDPS

    CAS:
    <p>Pseudouridine5'-OTBDPS [5-(5-O-TBDPS-β-D-ribofuranosyl)uracil] is an intermediate of Pseudouridine.</p>
    Fórmula:C25H30N2O6Si
    Forma y color:Solid
    Peso molecular:482.60

    Ref: TM-TSW-00962

  • CDK7-IN-31
    Targetmol
    + Info

    CDK7-IN-31

    CAS:
    CDK7-IN-31 (compound 13) is an effective and orally active inhibitor of cyclin-dependent kinase 7 (CDK7) with a dissociation constant (Kd) of 0.18 nM. This compound exhibits anticancer activity.
    Fórmula:C27H32F5N6O2P
    Forma y color:Solid
    Peso molecular:598.55

    Ref: TM-T201665

  • AB25583
    Targetmol
    + Info

    AB25583

    CAS:
    AB25583 is a small molecule inhibitor of Polθ helicase (Polθ-hel) with an IC50 of 6 nM. It selectively kills cells deficient in BRCA1/2 and synergizes with Olaparib in cancer cells harboring pathogenic BRCA1/2 mutations. AB25583 can be utilized in tumor research.
    Fórmula:C22H17ClN4O3S
    Forma y color:Solid
    Peso molecular:452.91

    Ref: TM-T200101

  • DYRK1-IN-1
    Targetmol
    + Info

    DYRK1-IN-1

    CAS:
    DYRK1-IN-1: Selective DYRK1A inhibitor with IC50 of 220 nM, good permeability, CNS penetrant for research, no P-glycoprotein issues.
    Fórmula:C12H12N6
    Forma y color:Solid
    Peso molecular:240.26

    Ref: TM-T60334

  • KL-50
    Targetmol
    + Info

    KL-50

    CAS:
    KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.
    Fórmula:C7H7FN6O2
    Forma y color:Solid
    Peso molecular:226.17

    Ref: TM-T200136

  • GR 83895
    Targetmol
    + Info

    GR 83895

    CAS:
    GR 83895 is an antagonist of prototype fibrinogen receptor.
    Fórmula:C29H39N9O8S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:673.74

    Ref: TM-T25460

  • Zorubicin
    Targetmol
    + Info

    Zorubicin

    CAS:
    <p>Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.</p>
    Fórmula:C34H35N3O10
    Forma y color:Solid
    Peso molecular:645.66

    Ref: TM-T69130

  • Galidesivir
    Targetmol
    + Info

    Galidesivir

    CAS:
    Galidesivir (BCX4430) is an antiviral compound that inhibits viral RNA-dependent RNA polymerase (RdRp) activity and reduces lung infections in infected animals.
    Fórmula:C11H15N5O3
    Pureza:96.73% - 99.13%
    Forma y color:Solid
    Peso molecular:265.27

    Ref: TM-T10491

  • PLK1-IN-11
    Targetmol
    + Info

    PLK1-IN-11

    CAS:
    PLK1-IN-11 (Cluster 4, 16953209) is a PLK1 inhibitor with an IC50 of 1 μM. It is applicable in research on various cancers such as pancreatic, ovarian, breast, and non-small cell lung cancer.
    Fórmula:C12H11N5O
    Forma y color:Solid
    Peso molecular:241.249

    Ref: TM-T205548

  • 6-B345TTQ
    Targetmol
    + Info

    6-B345TTQ

    CAS:
    6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.
    Fórmula:C22H20BrNO4
    Forma y color:Solid
    Peso molecular:442.303

    Ref: TM-T204244

  • And1 degrader 1
    Targetmol
    + Info

    And1 degrader 1

    CAS:
    And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.
    Fórmula:C26H27Cl2N3O
    Forma y color:Solid
    Peso molecular:468.42

    Ref: TM-T200443

  • Cdc7-IN-11
    Targetmol
    + Info

    Cdc7-IN-11

    CAS:
    Cdc7-IN-11 is a potent inhibitor of Cdc7 (IC50 ≤ 1 nM) and can be used in the study of proliferative diseases.
    Fórmula:C20H22F2N4O2S
    Forma y color:Solid
    Peso molecular:420.48

    Ref: TM-T62231

  • LN-439A
    Targetmol
    + Info

    LN-439A

    CAS:
    LN-439A (compound LN-439A) is a novel BAP1 inhibitor that suppresses the growth of basal-like breast cancer by degrading KLF5.
    Fórmula:C24H26FN3O4
    Forma y color:Solid
    Peso molecular:439.48

    Ref: TM-T200435

  • LNA-GMP
    Targetmol
    + Info

    LNA-GMP

    CAS:
    LNA-GMP, a nucleotide analogue, is utilized in the synthesis of oligonucleotides.
    Fórmula:C11H14N5O8P
    Forma y color:Solid
    Peso molecular:375.23

    Ref: TM-TSW-00965