Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(111 productos)
- CDK(526 productos)
- Detención del ciclo celular(4 productos)
- Chk(46 productos)
- DYRK(49 productos)
- Dynamin(26 productos)
- Ferroptosis(225 productos)
- HSP(179 productos)
- Integrin(256 productos)
- Kinesina(87 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(283 productos)
- PKC(111 productos)
- PLK(25 productos)
- ROCK(66 productos)
- Rho(2 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3756 productos de "Ciclo celular / Checkpoint"
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WRN inhibitor 13
CAS:WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.Fórmula:C16H20N2O5SForma y color:SolidPeso molecular:352.405DNA polymerase-IN-6
CAS:DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, with EC50 values of 0.33 µM for HCMV, 1.9 µM for HSV-1, 0.76 µM for HSV-2, and 0.066 µM for EBV.Fórmula:C26H28ClFN8O4Forma y color:SolidPeso molecular:571.003Hesperadin hydrochloride
Hesperadin hydrochloride is an ATP-competitive indolone inhibitor of Aurora A and B, with an IC50 value of 250 nM for Aurora B.Fórmula:C29H33ClN4O3SForma y color:SolidPeso molecular:553.12FR-β ligand 1
CAS:FR-β ligand 1 (III) is a ligand that specifically targets folate receptors, exhibiting antitumor activity, high selectivity, and strong affinity.Fórmula:C22H25N5O6Forma y color:SolidPeso molecular:455.46CDK9-IN-13
CDK9-IN-13 is a potent and selective CDK inhibitor (IC50<3 nM). CDK9-IN-13 has a very short half-life in rodents.Fórmula:C27H35N5O2Forma y color:SolidPeso molecular:461.6N-Isobutyryl-2', 3'-acetyl-guanosine
CAS:N-Isobutyryl-2', 3'-acetyl-guanosine is a derivative of guanosine.Fórmula:C18H23N5O8Forma y color:SolidPeso molecular:437.4042'-O-MOE-GMP
CAS:<p>2'-O-MOE-GMP is a nucleotide analogue that can be utilized in the synthesis of oligonucleotides.</p>Fórmula:C13H20N5O9PForma y color:SolidPeso molecular:421.30Mazethramycin
CAS:<p>Mazethramycin is an antitumor antibiotic that exerts its effects by disrupting DNA replication and RNA synthesis within cells. It is utilized in cancer research.</p>Fórmula:C17H19N3O4Peso molecular:329.35Chk1-IN-5
CAS:Chk1-IN-5 inhibits Chk1, blocking phosphorylation and suppressing colon cancer growth.Fórmula:C18H18FN7O2Forma y color:SolidPeso molecular:383.38DYRKs-IN-1 hydrochloride
CAS:DYRKs-IN-1 HCl inhibits DYRK1A (5 nM IC50) & DYRK1B (8 nM IC50) with antitumor properties.Fórmula:C30H31Cl2N7O4Forma y color:SolidPeso molecular:624.52CDK7-IN-18
CAS:CDK7-IN-18: potent, pyrimidine-based CDK7 inhibitor with cancer research potential.Fórmula:C22H24F3N7OSPureza:99.28%Forma y color:SolidPeso molecular:491.53CDK9-IN-38
CAS:<p>CDK9-IN-38 (compound 14) is a CDK9 inhibitor with IC50 values of 1.2 nM for wild-type CDK9 and 3.3 nM for the L156F mutant. It effectively inhibits tumor growth both in vitro and in vivo.</p>Fórmula:C22H23N5O3SForma y color:SolidPeso molecular:437.5154,5'-Dimethylangelicin-NHS
NHS-modified coumarin, 4,5'-Dimethylangelicin-NHS, shows photochemical activity & photosensitivity.Fórmula:C21H19NO7SForma y color:SolidPeso molecular:429.44CHK1-IN-2
CAS:CHK1-IN-2 is an inhibitor of checkpoint kinase 1 (CHK1; IC50: 6 nM).Fórmula:C20H22N4OSPureza:98%Forma y color:SolidPeso molecular:366.48MtTMPK-IN-9
MtTMPK-IN-9 moderately inhibits MtbTMPK (IC50: 48 μM), has submicromolar Mycobacterium activity, and is non-toxic, aiding tuberculosis research.Fórmula:C25H26N6O7Forma y color:SolidPeso molecular:522.51(Rac)-Plevitrexed
CAS:(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).Fórmula:C26H25FN8O4Pureza:98%Forma y color:SolidPeso molecular:532.53FT709
CAS:FT709 is a selective USP9X deubiquitinating enzyme inhibitor (IC50=82 nM) that reduces Makorin and ZNF598 levels, impairing ribosomal quality control pathways.Fórmula:C23H22N4O7SForma y color:SolidPeso molecular:498.51CB 30900
CAS:CB30900 is a novel and effective thymidylate synthase inhibitor.Fórmula:C31H32FN5O9Forma y color:SolidPeso molecular:637.61CLK1/2-IN-1
CAS:CLK1/2-IN-1 is a CLK1 and CLK2 inhibitor and it also inhibits SRPK1 and SRPK2.Fórmula:C21H20F3N7OPureza:98%Forma y color:SolidPeso molecular:443.42Ascofuranone
CAS:Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODHFórmula:C23H29ClO5Forma y color:SolidPeso molecular:420.93
