CymitQuimica logo
Ciclo celular / Checkpoint

Ciclo celular / Checkpoint

Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.

Subcategorías de "Ciclo celular / Checkpoint"

Mostrar 10 subcategorías más

Se han encontrado 3756 productos de "Ciclo celular / Checkpoint"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
productos por página.
  • 2-Amino-2'-fluoro-2'-deoxyadenosine
    Targetmol
    + Info

    2-Amino-2'-fluoro-2'-deoxyadenosine

    CAS:
    <p>2-Amino-2'-fluoro-2'-deoxyadenosine is a component of nucleic acids.</p>
    Fórmula:C10H13FN6O3
    Forma y color:Solid
    Peso molecular:284.25

    Ref: TM-TSW-00955

  • ROCK/HDAC-IN-1
    Targetmol
    + Info

    ROCK/HDAC-IN-1

    ROCK/HDAC-IN-1 (Compound 10h) serves as an orally effective inhibitor of ROCK/HDAC. This compound suppresses ROCK1/2 (IC50: 254.9 nM, 58.18 nM) and HDAC1/2/3/6/8 (IC50: 9.09, 8.03, 6.26, 0.41, 7.69 nM). It stimulates the activation of DAMPs, notably calreticulin (CRT) exposure and HMGB1 release, suggesting its potential as an inducer of immunogenic cell death (ICD). ROCK/HDAC-IN-1 exhibits antiproliferative effects against breast cancer cells (IC50: 0.37 μM for MDA-MB-231 cells), inhibits tumor growth, activates T cells, and shows no significant toxicity.
    Fórmula:C19H22N4O3S
    Forma y color:Solid
    Peso molecular:386.47

    Ref: TM-T201708

  • Tizolemide
    Targetmol
    + Info

    Tizolemide

    CAS:
    Tizolemide, a sulfonamide diuretic compound with alkaline properties, is cleared through the tubular transport system. It induces changes in the passive transport components across the basolateral membrane of isolated frog skin.
    Fórmula:C11H14ClN3O3S2
    Forma y color:Solid
    Peso molecular:335.83

    Ref: TM-T201590

  • Logo de CymitQuimica
    Targetmol
    + Info

    2'-F-AMP

    CAS:
    2'-F-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.
    Fórmula:C10H13FN5O6P
    Peso molecular:349.21

    Ref: TM-TSW-00945

  • Terpendole E
    Targetmol
    + Info

    Terpendole E

    CAS:
    Terpendole E is an atypical L5 site inhibitor.
    Fórmula:C28H39NO3
    Forma y color:Solid
    Peso molecular:437.61

    Ref: TM-T70289

  • Methyl 3-oxodecanoate
    Targetmol
    + Info

    Methyl 3-oxodecanoate

    CAS:
    <p>Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.</p>
    Fórmula:C11H20O3
    Forma y color:Solid
    Peso molecular:200.275

    Ref: TM-T206384

  • Logo de CymitQuimica
    Targetmol
    + Info

    3-deoxy-3-fluoro-β-D-Ribofuranose 25

    CAS:
    Compound 25, β-D-Ribofuranose, 3-deoxy-3-fluoro-, 1,2-diacetate 5-(4-methylbenzoate), exhibits strong activity in inhibiting the growth of tumor cells [1].
    Fórmula:C17H19FO7
    Peso molecular:354.33

    Ref: TM-T87696

  • RECTAS-2.0
    Targetmol
    + Info

    RECTAS-2.0

    CAS:
    <p>RECTAS-2.0 is a small molecule designed to correct RNA mis-splicing caused by the GLA c.639+919G&gt;A mutation, intended for research in Fabry disease.</p>
    Fórmula:C18H17ClN4O4
    Forma y color:Solid
    Peso molecular:388.805

    Ref: TM-T206725

  • 3-IN-PP1
    Targetmol
    + Info

    3-IN-PP1

    CAS:
    3-IN-PP1: PKD inhibitor (IC50: 94-108 nM for PKD1/2/3), broad anticancer agent for research.
    Fórmula:C17H18N6
    Forma y color:Solid
    Peso molecular:306.36

    Ref: TM-T60718

  • WEE1-IN-10
    Targetmol
    + Info

    WEE1-IN-10

    CAS:
    WEE1-IN-10 is a Wee1 kinase inhibitor that inhibits the growth of LOVO cells, such as pancreatic cancer, malignant melanoma, and malignant glioma.
    Fórmula:C28H30Cl2N8O
    Pureza:98.18%
    Forma y color:Solid
    Peso molecular:565.5

    Ref: TM-T89365

  • Z4P
    Targetmol
    + Info

    Z4P

    CAS:
    Z4P, an IRE1 inhibitor with blood-brain barrier permeability (BBB), inhibited glioblastoma growth and recurrence in combination with Temozolomide.
    Fórmula:C19H24N2O2
    Pureza:98.99%
    Forma y color:Solid
    Peso molecular:312.41

    Ref: TM-T87658

  • 2′-F-UDP
    Targetmol
    + Info

    2′-F-UDP

    CAS:
    2′-F-UDP is a nucleotide analogue used in the synthesis of oligonucleotides.
    Fórmula:C9H13FN2O11P2
    Forma y color:Solid
    Peso molecular:406.15

    Ref: TM-TSW-00958

  • Bersiporocin
    Targetmol
    + Info

    Bersiporocin

    CAS:
    <p>Bersiporocin is a novel prolyl-tRNA synthetase (PRS) inhibitor that exerts antifibrotic effects through downregulation of collagen synthesis in IPF.</p>
    Fórmula:C15H19Cl2N3O
    Pureza:98.88% - 99.79%
    Forma y color:Solid
    Peso molecular:328.24

    Ref: TM-T39739

  • DDO-6079
    Targetmol
    + Info

    DDO-6079

    CAS:
    DDO-6079 is an efficient CDC37 inhibitor. It suppresses the HSP90-CDC37 and CDC37-CDK4/6 chaperone complexes by binding to an allosteric site on CDC37. Additionally, DDO-6079 reduces the thermal stability of CDK6.
    Fórmula:C18H13ClN2O3
    Forma y color:Solid
    Peso molecular:340.76

    Ref: TM-T204112

  • Logo de CymitQuimica
    Targetmol
    + Info

    CYP2C19-IN-1

    CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.
    Fórmula:C26H26N2O6S
    Forma y color:Solid
    Peso molecular:494.56

    Ref: TM-T63337

  • 2-CEES
    Targetmol
    + Info

    2-CEES

    CAS:
    2-CEES is a mustard gas analogue that only forms DNA monoadducts. It induces centromere amplification in both human and mouse cells and can lead to chromosome instability.
    Fórmula:C4H9ClS
    Forma y color:Solid
    Peso molecular:124.632

    Ref: TM-T204286

  • SR121566A
    Targetmol
    + Info

    SR121566A

    CAS:
    SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).
    Fórmula:C20H25N5O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:431.51

    Ref: TM-T12999

  • Logo de CymitQuimica
    Targetmol
    + Info

    Antiangiogenic agent 2

    <p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>
    Fórmula:C26H26FN3O4
    Forma y color:Solid
    Peso molecular:463.5

    Ref: TM-T62931

  • Aurora B inhibitor 1
    Targetmol
    + Info

    Aurora B inhibitor 1

    CAS:
    Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki <0.010 uM) with potential anticancer activity for cancer research.
    Fórmula:C25H26ClF2N7O2
    Pureza:98.37%
    Forma y color:Solid
    Peso molecular:529.97

    Ref: TM-T12010

  • CDK12/13 ligand 1
    Targetmol
    + Info

    CDK12/13 ligand 1

    CAS:
    ALK-IN-29 (compound 4c) exhibits notable inhibitory activity against tyrosine kinases such as ALK, CDK2/CyclinE1, and FAK, with the strongest inhibition observed against ALK kinase, showing a 40.63% inhibition rate at a concentration of 10 μM. ALK-IN-29 is useful for cancer research.
    Fórmula:C26H26BrN5O
    Forma y color:Solid
    Peso molecular:504.42

    Ref: TM-T201159