Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
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Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
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5'-DMTr-3'dA(Bz)-methylphosphonami dite
<p>5’-DMTr-3’dA(Bz)-methylphosphonamidite, a purine nucleoside analog, exhibits wide-ranging antitumor activity, specifically targeting indolent lymphoid</p>Fórmula:C45H51N6O6PForma y color:SolidPeso molecular:802.9N1-(2-Methyl)propyl pseudouridine
<p>N1-(2-Methyl)propyl pseudouridine, a purine analog, targets lymphoid cancer by inhibiting DNA synthesis and inducing apoptosis.</p>Fórmula:C13H20N2O6Forma y color:SolidPeso molecular:300.31Psammaplin A
CAS:<p>Psammaplin A: marine-derived, inhibits HDAC/DNA methyltransferases, strong DAC1 blocker (IC50=0.9nM), antimicrobial against Gram-positive bacteria, anticancer.</p>Fórmula:C22H24Br2N4O6S2Forma y color:SolidPeso molecular:664.38Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Fórmula:C25H41N11O8SForma y color:SolidPeso molecular:655.727Endo-1,4-β-xylanase
CAS:<p>Endo-1,4-β-xylanase (CtXyn11A) is a type of xylan hydrolase that hydrolyzes the β-1,4-glycosidic bond of the xylan molecule.</p>Forma y color:Solid5'(R)-C-Methyl-5-fluorouridine
<p>5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.</p>Fórmula:C10H13FN2O6Forma y color:SolidPeso molecular:276.22(S)-DI-87
CAS:<p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>Fórmula:C23H30N6O3S2Pureza:99.42%Forma y color:SoildPeso molecular:502.65Deoxythymidine-5'-triphosphate
CAS:<p>Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.</p>Fórmula:C10H17N2O14P3Forma y color:SolidPeso molecular:482.167Methylcarbamyl PAF C-8
<p>Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.</p>Forma y color:Odour SolidPROTAC CDK9 degrader-8
<p>PROTAC CDK9 Degrader-8 (Compound 21) is a potent degrader of CDK9 with an IC50 of 0.01 μM, utilized in cancer research [1].</p>Fórmula:C44H52Cl2N10O7Pureza:98%Forma y color:SolidPeso molecular:903.85CDK1-IN-2
CAS:<p>CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 μM.</p>Fórmula:C17H11ClN2OPureza:98.53%Forma y color:SoildPeso molecular:294.73Cytarabine triphosphate
CAS:<p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>Fórmula:C9H16N3O14P3Forma y color:SolidPeso molecular:483.16Aclacinomycin A
CAS:<p>Aclacinomycin A has a wide range of applications in life science related research.</p>Fórmula:C42H53NO15Pureza:99.43%Forma y color:SolidPeso molecular:811.87BLINK15
<p>BLINK15 is a blood-brain barrier-permeable Cdk5 inhibitor. It reduces CDK5 activity in CDK5/p35 (IC50= 29.34 nM) and CDK5/p25 (IC50= 12.08 nM) complexes. Additionally, BLINK15 exhibits antidiabetic and neuroprotective effects. It lowers blood glucose levels in type 2 diabetes (T2D) mice, enhances cognitive abilities, and diminishes neurodegenerative lesions.</p>Forma y color:Odour SolidCDK2-IN-43
<p>CDK2-IN-43 (Compound 3a) is a CDK2-cyclin E2 inhibitor with an IC50 value of 6.0 nM. It is applicable to cancer research.</p>Fórmula:C19H27N7OForma y color:SolidPeso molecular:369.464ROCK-IN-32
CAS:<p>ROCK-IN-32 is an effective Rho-kinase inhibitor.</p>Fórmula:C20H17Cl2N3O2Pureza:98%Forma y color:SolidPeso molecular:402.27Ceftriaxone
CAS:<p>Ceftriaxone: cephalosporin antibiotic, effective against Gram-positive/negative bacteria, with anti-inflammatory/antioxidant properties.</p>Fórmula:C18H18N8O7S3Pureza:96.08%Forma y color:SolidPeso molecular:554.58Thailanstatin C
CAS:<p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>Fórmula:C30H46ClNO9Forma y color:SolidPeso molecular:600.15m7GpppUmpG
CAS:<p>m7GpppUmpG, a trinucleotide cap analogue, enables RNA synthesis with cap 0 or 1 structures.</p>Fórmula:C31H42N12O26P4Forma y color:SolidPeso molecular:1122.63CCT241533 dihydrochloride
CAS:<p>Potent Chk2 inhibitor with 3 nM IC50, 63-fold more selective over Chk1, affects 84 kinases, reduces DNA damage response and apoptosis in cells.</p>Fórmula:C23H29Cl2FN4O4Forma y color:SolidPeso molecular:515.41
