Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
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Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
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5'-O-DMT-PAC-dA
CAS:<p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>Fórmula:C39H37N5O7Forma y color:SolidPeso molecular:687.74LDV FITC
CAS:<p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>Fórmula:C69H81N11O17SPureza:98%Forma y color:SolidPeso molecular:1368.53Erythromycin A dihydrate
CAS:<p>Erythromycin dihydrate, a macrolide antibiotic from Streptomyces erythreus, targets 50S ribosomal subunits, blocking protein synthesis.</p>Fórmula:C37H69NO14Forma y color:SolidPeso molecular:751.94AV-153
CAS:<p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>Fórmula:C14H19NNaO6Forma y color:SolidPeso molecular:320.2978-NH2-ATP
CAS:<p>8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.</p>Fórmula:C10H17N6O13P3Forma y color:SolidPeso molecular:522.205-Caroxy uracil-1-yl acetic acid benzyl ester
<p>5-Caroxy uracil-1-yl acetic acid benzyl ester, a purine analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.</p>Fórmula:C14H12N2O6Forma y color:SolidPeso molecular:304.25Isocytosine
CAS:<p>Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C4H5N3OForma y color:White To Off-White SolidPeso molecular:111.1IV-361
CAS:<p>IV-361, an orally active and selective CDK7 inhibitor with a Ki value of less than or equal to 50 nM, demonstrates potent anti-cancer activity (US20190256531A1</p>Fórmula:C23H32FN5O2SiForma y color:SolidPeso molecular:457.625Rev 2'-O-MOE-C(Bz)-5'-amidite
<p>'Rev 2’-O-MOE-C(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.</p>Fórmula:C49H58N5O10PForma y color:SolidPeso molecular:907.99Dafsolimab
CAS:<p>Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is</p>Forma y color:LiquidSR15006
CAS:<p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>Fórmula:C16H20ClN3O4SPureza:99.87%Forma y color:SoildPeso molecular:385.87Nogalamycin
CAS:<p>Nogalamycin is an anthracycline antibiotic with antitumor properties produced by soil bacteria Streptomyces nogalater.</p>Fórmula:C39H49NO16Pureza:98%Forma y color:SolidPeso molecular:787.812Chrexanthomycin C
<p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>Fórmula:C31H24O15Forma y color:SolidPeso molecular:636.51Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Fórmula:C25H41N11O8SForma y color:SolidPeso molecular:655.727DHFR-IN-8
<p>DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth.</p>Fórmula:C18H14N6SForma y color:SolidPeso molecular:346.41N1-Methylpseudouridine-5′-triphosphate tetralithium
<p>N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.</p>Fórmula:C10H13Li4N2O15P3Forma y color:SolidPeso molecular:521.9GRGDSP
CAS:<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Fórmula:C22H37N9O10Pureza:98%Forma y color:SolidPeso molecular:587.583'-β-C-Methyl-N6-isopentenyl adenosine
<p>3’-Beta-C-Methyl-N6-isopentenyl adenosine is an adenosine analog.</p>Fórmula:C16H23N5O4Forma y color:SolidPeso molecular:349.38Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Fórmula:C21H25FN4O2Forma y color:SolidPeso molecular:384.453'-Deoxy-GTP trisodium
<p>3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) trisodium, an analog of GTP, functions as an RNA chain terminator, thereby inhibiting RNA synthesis. It is capable of suppressing dengue virus DENV NS5 RdRp with an IC50 value of 0.02 μM.</p>Forma y color:Odour Solid
