Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(226 productos)
- HSP(179 productos)
- Integrin(253 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(273 productos)
- PKC(124 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3873 productos de "Ciclo celular / Checkpoint"
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Methylcarbamyl PAF C-8
Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.Forma y color:Odour SolidEndo-1,4-β-xylanase
CAS:Endo-1,4-β-xylanase (CtXyn11A) is a type of xylan hydrolase that hydrolyzes the β-1,4-glycosidic bond of the xylan molecule.Forma y color:SolidBarasertib
CAS:AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.Fórmula:C26H31FN7O6PPureza:99.92% - 99.97%Forma y color:SolidPeso molecular:587.54m7GpppUmpG
CAS:m7GpppUmpG, a trinucleotide cap analogue, enables RNA synthesis with cap 0 or 1 structures.Fórmula:C31H42N12O26P4Forma y color:SolidPeso molecular:1122.63GSK270822A
CAS:GSK270822A is a selective ROCK1 inhibitor. GSK270822A exhibits IC50 of 9nM, 1100nM, 1550nM for ROCK1, RSK1, p70S6K, respectively.Fórmula:C24H20N4O2Pureza:98.64% - 99.78%Forma y color:SolidPeso molecular:396.44Ref: TM-T27467
1mg133,00€5mg314,00€10mg416,00€25mg632,00€50mg847,00€100mg1.134,00€200mg1.513,00€1mL*10mM (DMSO)323,00€(Gly0.8Nap0.2)20
(Gly0.8Nap0.2)20 is a dual-target compound effective against fungal membranes and DNA. It exhibits antimicrobial properties.Fórmula:C139H236N38O24·16(C2F3O2)Bz-rC Phosphoramidite
CAS:Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.Fórmula:C52H66N5O9PSiForma y color:SolidPeso molecular:964.185Lamifiban trifluoroacetate
CAS:Lamifiban trifluoroacetate is an antagonist of the nonpeptide platelet fibrinogen receptor (GPIIb/IIIa).Fórmula:C26H29F3N4O8Forma y color:SolidPeso molecular:582.533c(phg-isoDGR-(NMe)k) TFA
C(phg-isoDGR-(NMe)k) TFA is a selective and potent ligand for α5β1-integrin, exhibiting an IC50 of 2.9 nM [1].Fórmula:C29H42F3N9O9Forma y color:SolidPeso molecular:717.69A-130A
CAS:A-130A is a polycyclic polyether compound belonging to the nigericin group of antibiotics generated by Streptomyces hygroscopicus strain.Fórmula:C47H78O13Pureza:98%Forma y color:SolidPeso molecular:851.11Carbazole
CAS:Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.Fórmula:C12H9NPureza:99.82%Forma y color:SolidPeso molecular:167.211AV-153
CAS:AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.Fórmula:C14H19NNaO6Forma y color:SolidPeso molecular:320.297USP7-IN-16
CAS:USP7-IN-16 (Compound 61) is a selective inhibitor of USP7, with IC50 values of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. This compound exhibits antitumor activity in mice and holds potential for research in the field of oncology.Fórmula:C43H45N7O6SForma y color:SolidPeso molecular:787.93PKMYT1-IN-6
PKMYT1-IN-6 (compound 98) is an inhibitor of PKMYT1, exhibiting an IC50 of less than 50nM.Forma y color:Odour SoliddAURK-4
CAS:dAURK-4, a derivative of Alisertib, functions as a potent and selective degrader of AURKA (Aurora A), exhibiting anticancer properties [1].Fórmula:C52H52ClFN8O12Forma y color:SolidPeso molecular:1035.47Rev 2'-O-MOE-C(Bz)-5'-amidite
'Rev 2’-O-MOE-C(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Fórmula:C49H58N5O10PForma y color:SolidPeso molecular:907.99DSPE-PEG1000-cRGD
DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.Forma y color:Odour SolidCDK9-IN-25
CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM.Fórmula:C15H16FN5Pureza:98%Forma y color:SolidPeso molecular:285.32Biotin-PEG8-Vidarabine
Biotin-PEG8-Vidarabine is an antiviral PEG linker targeting herpes and varicella zoster with adenosine analog Vidarabine.Fórmula:C36H60N8O13SForma y color:SolidPeso molecular:844.97PLK1-IN-2
CAS:PLK1-IN-2 is a PLK1 kinase inhibitor with an IC 50 value of 0.384 μM.Fórmula:C24H27FN8OSForma y color:SolidPeso molecular:494.59
