Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(114 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(179 productos)
- Integrin(262 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(126 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3888 productos de "Ciclo celular / Checkpoint"
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Suricapavir
CAS:Suricapavir is an effective viral replication inhibitor with antiviral activity.Fórmula:C41H29ClF9N9O4SForma y color:SolidPeso molecular:950.23CDK2/PIM1-IN-1
CDK2/PIM1-IN-1 is an inhibitor of the kinases CDK2 (IC50: 0.27 μM) and PIM1 (IC50: 0.67 μM). It can induce apoptosis (cell death) and reduce the expression of TNF-α, which promotes tumors. CDK2/PIM1-IN-1 exhibits antitumor activity.
Forma y color:Odour Solid12R-LOX-IN-2
CAS:12R-LOX-IN-2 is a 12R-LOX inhibitor that inhibits the hyperproliferation of psoriatic cells and can be used in the study of psoriasis and other skin diseases.Fórmula:C19H13NOPureza:99.92%Forma y color:SolidPeso molecular:271.31Erythromycin A dihydrate
CAS:Erythromycin dihydrate, a macrolide antibiotic from Streptomyces erythreus, targets 50S ribosomal subunits, blocking protein synthesis.Fórmula:C37H69NO14Forma y color:SolidPeso molecular:751.94PLK1-IN-2
CAS:PLK1-IN-2 is a PLK1 kinase inhibitor with an IC 50 value of 0.384 μM.Fórmula:C24H27FN8OSForma y color:SolidPeso molecular:494.59wrwycr-NH2 TFA
wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.Forma y color:Odour Solid1-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine
1-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine is an adenosine analog.Fórmula:C18H21N5O5Forma y color:SolidPeso molecular:387.39Biotin-PEG8-Vidarabine
Biotin-PEG8-Vidarabine is an antiviral PEG linker targeting herpes and varicella zoster with adenosine analog Vidarabine.Fórmula:C36H60N8O13SForma y color:SolidPeso molecular:844.97DG1
DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressingFórmula:C19H17N5O5SForma y color:SolidPeso molecular:427.43Nogalamycin
CAS:Nogalamycin is an anthracycline antibiotic with antitumor properties produced by soil bacteria Streptomyces nogalater.Fórmula:C39H49NO16Pureza:98%Forma y color:SolidPeso molecular:787.8125'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.Fórmula:C38H47N3O8SiForma y color:SolidPeso molecular:701.892Rachelmycin
CAS:Rachelmycin, a potent antibiotic and antitumor agent from Streptomyces zelensis, binds to DNA's minor groove.Fórmula:C37H33N7O8Forma y color:SolidPeso molecular:703.712TAC
CAS:TAC is a TERT (telomerase reverse transcriptase) activator, promotes telomere synthesis, reduces cellular senescence and inflammatory cytokinesFórmula:C14H12ClF2NO2SPureza:99.20%Forma y color:SolidPeso molecular:331.77Ref: TM-T201368
1mg38,00€5mg67,00€10mg95,00€25mg169,00€50mg260,00€100mg404,00€200mg676,00€1mL*10mM (DMSO)77,00€Fibronectin CS1 Peptide
CAS:Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.Fórmula:C38H64N8O15Pureza:98%Forma y color:SolidPeso molecular:872.96N6-Methyl-2'-O-(2-methoxyethyl) adenosine
N6-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Fórmula:C14H21N5O5Forma y color:SolidPeso molecular:339.35Activated Protein C (390-404), human TFA
APC's 390-404 peptide region key to anticoagulation, binds antibodies/proteins, inactivates cofactors Va/VIIIa.Fórmula:C93H131F3N22O25Pureza:98%Forma y color:SolidPeso molecular:2014.16GSK2850163 (S enantiomer)
CAS:GSK2850163 (S enantiomer) is the inactive enantiomer of GSK2850163. GSK2850163 is an novel inhibitor of inositol-requiring enzyme-1 alpha (IRE1a).
Fórmula:C24H29Cl2N3OPureza:98.40%Forma y color:SolidPeso molecular:446.41VPC-18005
CAS:VPC-18005: a luciferase inhibitor that blocks ERG-induced transcription by binding ERG-ETS, hindering DNA attachment.
Fórmula:C15H17N3O3SPureza:99.95%Forma y color:SoildPeso molecular:319.38Risuteganib
CAS:Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide that regulates the functions of multiple integrin isoforms.
Fórmula:C22H39N9O11SPureza:98%Forma y color:SolidPeso molecular:637.66N6-Ethyl-2'-β-C-ethynyl adenosine
N6-Ethyl-2’-beta-C-ethynyl adenosine is a purine nucleoside analog.Fórmula:C14H17N5O4Forma y color:SolidPeso molecular:319.32
