Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(115 productos)
- CDK(546 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(269 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(274 productos)
- PKC(126 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3906 productos de "Ciclo celular / Checkpoint"
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TC113
TC113, a c(RGDyK)-linked Gemcitabine, targets αvβ3 integrin, entering A549 cells, and inhibits WM266.4 and A549 cell growth.Fórmula:C37H50F2N12O13Forma y color:SolidPeso molecular:908.86MSH-TP15e
MSH-TP15e is a human-derived monoclonal antibody inhibitor that targets intercellular adhesion molecule-1 (ICAM-1). By recruiting natural killer cells, MSH-TP15e significantly induces antibody-dependent cell-mediated cytotoxicity (ADCC) activity, thereby inhibiting tumor cell growth. MSH-TP15e shows potential for research in multiple myeloma (MM).Forma y color:Odour Liquid8β,9α-Dihydroxylindan-4(5),7(11)-dien-8α,12-olide
CAS:8β,9α-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide (compound 3), a sesquiterpene, exhibits anti-LIMK1 activity and inhibits cell motility [1].Fórmula:C15H18O4Forma y color:SolidPeso molecular:262.3AR-13324 analog mesylate
AR-13324 analog mesylate is an inhibitor of Rho-kinase and a norepinephrine transporter and reduces intraocular pressure in normotensive monkey eyes.Fórmula:C29H33N3O9S2Pureza:98%Forma y color:SolidPeso molecular:631.72GK13S
G13KS: UCHL1 ligand, deubiquitinase inhibitor; reduces monoubiquitin in glioblastoma cells.Fórmula:C21H22N6O2Forma y color:SolidPeso molecular:390.44UnyLinker 12 TEA
UnyLinker 12 TEA is a versatile linker used in the synthesis of oligoribonucleotides.Fórmula:C39H35NO10C6H15NForma y color:SolidPeso molecular:778.34655Carboxy-pyridostatin
CAS:Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.
Fórmula:C35H34N10O7Forma y color:SolidPeso molecular:706.71(+)-Glaucarubinone
(+)-Glaucarubinone is a natural product that can be used as a reference standard.Fórmula:C25H34O10Forma y color:SolidPeso molecular:494.537Cyclo(Ala-Arg-Gly-Asp-Mamb)
CAS:Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective antagonist of the RGD peptide with potential applications in pulmonary arterial hypertension research [1].Fórmula:C23H32N8O7Pureza:98%Forma y color:SolidPeso molecular:532.55dUTP trisodium
CAS:dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.
Fórmula:C9H12N2Na3O14P3Pureza:100.00%Forma y color:SolidPeso molecular:534.095'-O-TBDMS-Bz-dA
CAS:5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.Fórmula:C23H31N5O4SiForma y color:SolidPeso molecular:469.617CDK8-IN-12
CAS:CDK8-IN-12: selective CDK8 inhibitor (Ki 14 nM), oral anticancer, blocks GSK-3α/β, PCK-θ, halts MV4-11 cell growth.Fórmula:C21H20ClN3O2Pureza:98.55% - 99.22%Forma y color:SoildPeso molecular:381.86Ref: TM-T72048
1mg52,00€5mg101,00€1mL*10mM (DMSO)116,00€10mg150,00€25mg250,00€50mg363,00€100mg509,00€200mg695,00€Biotin-PEG7-C2-NH-Vidarabine-S-CH3
Biotin-PEG7-C2-NH-Vidarabine-S-CH3 is a PEG linker with Vidarabine, an anti-herpes/zoster antiviral.Fórmula:C37H62N8O12S2Forma y color:SolidPeso molecular:875.06KL4-219A
KL4-219A is a selective covalent degrader of the MYC, inhibiting MYC transcriptional activity and degrading MYC in a proteasome-dependent manner .Fórmula:C20H22N2O3SPureza:99.68%Forma y color:SolidPeso molecular:370.47CDK-IN-12
CAS:CDK-IN-12 (Example 20), a CDK inhibitor, effectively inhibits CDK4/6, demonstrating IC50 values below 20 nM [1].Fórmula:C26H29FN6OSForma y color:SolidPeso molecular:492.61Cimpuciclib
CAS:Cimpuciclib is a cyclin-dependent kinase(CDK) inhibitor and antineoplastic.Fórmula:C30H35FN8OForma y color:SolidPeso molecular:542.6631-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine
1-(β-D-Xylofuranosyl)-N6-(m-trifluoromethylbenzyl)adenine is an adenosine analog.Fórmula:C18H18F3N5O4Forma y color:SolidPeso molecular:425.36Bimosiamose
CAS:Bimosiamose has anti-inflammatory effects[1].Fórmula:C46H54O16Pureza:98%Forma y color:SolidPeso molecular:862.91MM41
CAS:MM41 is a human telomeric and gene promoter DNA quadruplex stabilizer with an IC50 of <10 nM against the MIA PaCa-2 pancreatic cancer cell line.Fórmula:C44H66N10O6Pureza:99.25%Forma y color:SolidPeso molecular:831.06Ref: TM-T60028
1mg50,00€5mg110,00€1mL*10mM (DMSO)152,00€10mg170,00€25mg278,00€50mg371,00€100mg494,00€200mg675,00€AD16
CAS:AD16 (Acetamide) acts as an inhibitor of LINE-1 retrotransposon endonuclease, exhibiting an IC50 value of 4.7 μM. It decreases LINE-1 retrotransposition in senescent cells and mitigates the resulting DNA damage and inflammation.Fórmula:C24H20N14O3S2Forma y color:SolidPeso molecular:616.64
