Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
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Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
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N1-Methylpseudouridine-5′-triphosphate tetralithium
<p>N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.</p>Fórmula:C10H13Li4N2O15P3Forma y color:SolidPeso molecular:521.9PAT-LM1
<p>PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.</p>Forma y color:Odour LiquidMethylcarbamyl PAF C-8
<p>Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.</p>Forma y color:Odour Solidm7GpppGpG
CAS:<p>m7GpppGpG, a trinucleotide cap, protects mRNA from 5′ exonucleases & aids splicing and translation.</p>Fórmula:C31H41N15O25P4Forma y color:SolidPeso molecular:1147.64MRK-952
<p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>Fórmula:C20H20ClF3N6Forma y color:SolidPeso molecular:436.861N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine
<p>N3,5-Dimethyl-2’-O-(2-methoxyethyl) uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>Fórmula:C14H22N2O7Forma y color:SolidPeso molecular:330.33Stigmatellin
CAS:<p>Stigmatellin is an antibiotic derived from the cell mass of the myxobacterium, effective against yeasts (yeasts), filamentous fungi (filamentous fungi), and several Gram-positive bacteria (Gram-positive bacteria). Additionally, it serves as a potent inhibitor of photosynthetic electron (photosynthetic electron) transfer. Stigmatellin utilizes various sugars, polysaccharides, and acids from the citric acid cycle as substrates, inhibiting RNA and protein synthesis. It has two different inhibitory sites: one located on the reducing side of photosystem II and the other at the cytochrome b6/f complex. Stigmatellin holds potential for use in antimicrobial and photosynthesis research.</p>Fórmula:C30H42O7Forma y color:SolidPeso molecular:514.65PP-C8
<p>PP-C8: PROTAC CDK12-Cyclin K degrader with DC50s 416/412 nM; synergizes with PARP inhibitor against TNBC.</p>Fórmula:C43H51FN12O7Forma y color:SolidPeso molecular:866.94CDK5-IN-1
CAS:<p>CDK5-IN-1: Potent CDK5 inhibitor (<10 nM) used in kidney disease research.</p>Fórmula:C24H25FN6O3SForma y color:SolidPeso molecular:496.56Ribonuclease T1
CAS:<p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>Forma y color:SolidPD-1/PD-L1-IN-50
<p>Compound LG-12, known chemically as PD-1/PD-L1-IN-50, is an inhibitor of PD-1/PD-L1. It enhances the secretion of IFN-γ, promotes the activation of CD8+ T cells, and activates T cell-mediated anti-tumor immunity.</p>Forma y color:Odour SolidRemdesivir nucleoside monophosphate
CAS:<p>Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.</p>Fórmula:C12H14N5O7PForma y color:SolidPeso molecular:371.24Sarecycline hydrochloride
CAS:<p>Sarecycline hydrochloride is a narrow-spectrum tetracycline antibiotic with antimicrobial and anti-inflammatory activity.</p>Fórmula:C24H30ClN3O8Pureza:99.23%Forma y color:SolidPeso molecular:523.96CDK2/PIM1-IN-1
<p>CDK2/PIM1-IN-1 is an inhibitor of the kinases CDK2 (IC50: 0.27 μM) and PIM1 (IC50: 0.67 μM). It can induce apoptosis (cell death) and reduce the expression of TNF-α, which promotes tumors. CDK2/PIM1-IN-1 exhibits antitumor activity.</p>Forma y color:Odour SolidRifalazil
CAS:<p>Rifalazil (KRM-1648) is a benzophenazine antibiotic with antibacterial activity, useful for research on chlamydia infections.</p>Fórmula:C51H64N4O13Pureza:98%Forma y color:SolidPeso molecular:941.07JB-11 isethionate
CAS:<p>JB-11 isethionate is a bioactive chemical.</p>Fórmula:C21H29N5O7SForma y color:SolidPeso molecular:495.55N1-Methyl-2'-O-(2-methoxyethyl) guanosine
<p>N1-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.</p>Fórmula:C14H21N5O6Forma y color:SolidPeso molecular:355.35Anticancer agent 84
CAS:<p>Anticancer agent 84 inhibits c-MYC transcription by stabilizing G4 structures, aiding cancer research.</p>Fórmula:C57H67N7O9Forma y color:SolidPeso molecular:994.18ROCK-IN-5
CAS:<p>ROCK-IN-5 (I-B-37) inhibits kinases like ROCK/ERK/GSK; may aid in cardiac and neuro disease studies.</p>Fórmula:C16H11ClFN3OSPureza:99.72% - 99.83%Forma y color:SolidPeso molecular:347.79L-Inosine
CAS:<p>L-Inosine, an endogenous purine nucleoside from adenosine metabolism, has anti-inflammatory, antinociceptive, immunomodulatory, and neuroprotective properties.</p>Fórmula:C10H12N4O5Forma y color:SolidPeso molecular:268.23PKMYT1-IN-3
<p>PKMYT1-IN-3 (compound 8ma) is a potent, selective inhibitor of PKMYT1, demonstrating an IC50 of 16.5 nM and exhibiting antitumor activity.</p>Fórmula:C24H26FN5O2Forma y color:SolidPeso molecular:435.49AB-3PRGD2
CAS:<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Fórmula:C137H215IN30O45SForma y color:SolidPeso molecular:3161.323'-Deoxyuridine-5'-triphosphate trisodium
<p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>Fórmula:C9H12N2Na3O14P3Forma y color:SoildPeso molecular:534.08TLR7 agonist 12
CAS:<p>TLR7 agonist 12, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.</p>Fórmula:C14H19N5O8Forma y color:SolidPeso molecular:385.332-Methylbutyrylcarnitine chloride
<p>2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.</p>Fórmula:C12H24ClNO4Forma y color:SolidPeso molecular:281.783'-Deoxy-N1-Methyl inosine
<p>3’-Deoxy-N1-Methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.</p>Fórmula:C11H14N4O4Forma y color:SolidPeso molecular:266.25AURKA against 1
<p>Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase (AURKA) with an IC50 of less than 0.5 nM, targeting the acetylation of endogenous lysine (K162) and exhibiting anti-tumor cell proliferation activity. The kinase activity of AURKA, acetylated at K162 and induced by AURKA against 1, is reversibly restored in HCT116 cells transfected with SIRT3.</p>Fórmula:C28H32FN9O2Forma y color:SolidPeso molecular:545.612'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium
<p>2’-O-Methyl-5-methyluridine 5’-triphosphate (triethylammonium), a thymidine analog, exhibits insertional activity in replicated DNA.</p>Fórmula:C29H64N5O15P3Forma y color:SolidPeso molecular:815.76Pseudouridimycin
CAS:<p>Pseudouridimycin: a C-nucleoside antibiotic, inhibits bacterial RNAP, targets Gram-negative and Gram-positive bacteria.</p>Fórmula:C17H26N8O9Pureza:98%Forma y color:SolidPeso molecular:486.44BTO-1
CAS:<p>BTO-1: Plk inhibitor effective in regulating phosphorylation.</p>Fórmula:C9H4N4O4SForma y color:SolidPeso molecular:264.22Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Fórmula:C25H41N11O8SForma y color:SolidPeso molecular:655.727Diguanosine 5′-triphosphate
CAS:<p>Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.</p>Fórmula:C20H27N10O18P3Forma y color:SolidPeso molecular:788.409N3-(2S)-[2-(tert-Butoxycarbonyl)amino-3-(tert-butoxy carbonyl)]propyluridine
<p>N3-(2S)-propyluridine is a uridine analog with potential as an antiepileptic and for antihypertensive agent research.</p>Fórmula:C22H35N3O10Forma y color:SolidPeso molecular:501.53Mulnitorsen
CAS:<p>Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].</p>Fórmula:C172H217N74O82P17S17Forma y color:SolidPeso molecular:5704.66EFdA-TP
CAS:<p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>Fórmula:C12H15FN5O12P3Forma y color:SolidPeso molecular:533.1953'-O-(4,4'-Dimethoxy trityl)-2'-O-(2-methoxyethyl)-5-methyluridine
<p>3’-O-(4,4’-Dimethoxy trityl)-2’-O-(2-methoxyethyl)-5-methyluridine, a purine nucleoside analog, exhibits extensive antitumor properties against indolent</p>Fórmula:C34H38N2O9Forma y color:SolidPeso molecular:618.67Ascochlorin A
CAS:<p>Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitor</p>Fórmula:C23H31ClO4Forma y color:SolidPeso molecular:406.955'-O-DMT-N4-Ac-2'-F-dC
CAS:<p>5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C32H32FN3O7Forma y color:SolidPeso molecular:589.615'-O-DMT-PAC-dA
CAS:<p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>Fórmula:C39H37N5O7Forma y color:SolidPeso molecular:687.74CDK12-IN-6
CAS:<p>CDK12-IN-6, a pyrazolotriazine, strongly inhibits CDK12 (IC50 1.19 μM at 2 mM ATP), but not CDK2/Cyclin E or CDK9/Cyclin T1 (both IC50 >20 μM).</p>Fórmula:C20H21F2N9Forma y color:SolidPeso molecular:425.448Nuclease S1
CAS:<p>Nuclease S1 breaks down ssDNA and RNA, trims protruding ends of dsDNA.</p>Forma y color:Solid5-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine
<p>5-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine, a purine nucleoside analog, exhibits widespread antitumor activity specifically against indolent lymphoid</p>Fórmula:C27H28N2O8Forma y color:SolidPeso molecular:508.52JH-XVI-178
CAS:<p>JH-XVI-178: potent CDK8/19 inhibitor with good pharmacokinetics, low clearance, moderate oral bioavailability.</p>Fórmula:C22H22ClN7OForma y color:SolidPeso molecular:435.92Trimethoprim hydrochloride
CAS:<p>Trimethoprim hydrochloride: oral, broad-spectrum antibiotic, DHFR inhibitor, treats UTIs, shigellosis, pneumocystis pneumonia, may block Influenza A with zinc.</p>Fórmula:C14H19ClN4O3Forma y color:SolidPeso molecular:326.78Eesperamicin A1
CAS:<p>Esperamicin A1, a powerful antitumor drug, comes from Actinomadura verrucosospora.</p>Fórmula:C59H80N4O22S4Forma y color:SolidPeso molecular:1325.542-Amino-6-O-methyl-2'-O-methyl purine riboside
<p>2-Amino-6-O-methyl-2’-O-methyl purine riboside, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid</p>Fórmula:C12H17N5O5Forma y color:SolidPeso molecular:311.29Carbazole
CAS:<p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>Fórmula:C12H9NPureza:99.82%Forma y color:SolidPeso molecular:167.211Fradafiban hydrochloride
<p>Fradafiban (BIBU-52) is a nonpeptide GPIIb/IIIa antagonist with Kd 148 nM for human platelets.</p>Fórmula:C20H22ClN3O4Forma y color:SolidPeso molecular:403.86m7GpppAmpG
CAS:<p>M7GpppAmpG is a trinucleotide 5′ cap analog, exhibiting capping efficiencies of 90% for the produced RNAs [1].</p>Fórmula:C32H43N15O24P4Forma y color:SolidPeso molecular:1145.66Rev 2'-O-MOE-A(Bz)-5'-amidite
<p>'Rev 2’-O-MOE-A(Bz)-5’-amidite is a nucleoside analog specifically categorized within the purine subset, renowned for its wide-ranging antitumor efficacy</p>Fórmula:C50H58N7O9PForma y color:SolidPeso molecular:932.01SR15006
CAS:<p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>Fórmula:C16H20ClN3O4SPureza:99.87%Forma y color:SoildPeso molecular:385.87cis-Lomibuvir
CAS:<p>cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.</p>Fórmula:C25H35NO4SForma y color:SolidPeso molecular:445.61Heliquinomycin
CAS:<p>Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.</p>Fórmula:C33H30O17Forma y color:SolidPeso molecular:698.586USP7-IN-10 hydrochloride
<p>USP7-IN-10 hydrochloride, also known as compound 1, is a potent inhibitor of the enzyme ubiquitin-specific protease 7 (USP7), exhibiting an IC50 value of 13.39</p>Fórmula:C26H30Cl2N4O3SForma y color:SolidPeso molecular:549.51(1S,3R,5R)-PIM447 dihydrochloride
<p>(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).</p>Fórmula:C24H25Cl2F3N4OPureza:98%Forma y color:SolidPeso molecular:513.385-O-TBDMS-N4-Benzoyl-2-deoxycytidine
CAS:<p>5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.</p>Fórmula:C22H31N3O5SiForma y color:SolidPeso molecular:445.581-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine
<p>1-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine is an adenosine analog.</p>Fórmula:C18H21N5O5Forma y color:SolidPeso molecular:387.396-Mthoxy-9-β-D-(2-C-ethynyl-ribofuranosyl) purine
<p>6-Methoxy-9-β-D-ethynyl-purine: a purine analog with antitumor action, impeding DNA synthesis and inducing apoptosis.</p>Fórmula:C13H14N4O5Forma y color:SolidPeso molecular:306.27N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-2'-deoxycytidine
<p>N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-5-methyl-2’-deoxycytidine, a purine nucleoside analog, exhibits broad antitumor activity particularly against indolent</p>Fórmula:C33H35N3O7Forma y color:SolidPeso molecular:585.65Ganodermaones B
<p>Ganodermaones B is a renal fibrosis inhibitor. Ganodermaones B inhibits TGF-β1-induced collagen I and fibronectin expression .</p>Fórmula:C21H26O5Forma y color:SolidPeso molecular:358.43Chrysomycin A
CAS:<p>Chrysomycin A is an antibiotic that can be derived from Streptomyces.</p>Fórmula:C28H28O9Forma y color:SolidPeso molecular:508.52Xylocytidine
CAS:<p>Xylocytidine is a biochemical.</p>Fórmula:C9H13N3O5Forma y color:SolidPeso molecular:243.22Biotin-PEG7-C2-NH-Vidarabine-S-CH3
<p>Biotin-PEG7-C2-NH-Vidarabine-S-CH3 is a PEG linker with Vidarabine, an anti-herpes/zoster antiviral.</p>Fórmula:C37H62N8O12S2Forma y color:SolidPeso molecular:875.06Mumefural
CAS:<p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>Fórmula:C12H12O9Forma y color:SolidPeso molecular:300.22Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester
<p>Uridine analogue with antitumor effects; inhibits DNA synthesis, induces apoptosis in lymphoid cancers.</p>Fórmula:C24H24N2O9Forma y color:SolidPeso molecular:484.4623-Oxa-OSW-1
CAS:<p>23-Oxa-OSW-1 (SBF-1), a derivative of OSW-1, serves as a potent inhibitor of the osterol-binding protein (OSBP) with demonstrated antitumor activity [1] [2].</p>Fórmula:C54H82O16Forma y color:SolidPeso molecular:987.22Rev 2'-O-MOE-C(Bz)-5'-amidite
<p>'Rev 2’-O-MOE-C(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.</p>Fórmula:C49H58N5O10PForma y color:SolidPeso molecular:907.99GSK299423
CAS:<p>GSK299423: Antibiotic possibly effective against bacteria with New Delhi metal-β-lactamase, targeting topoisomerases.</p>Fórmula:C25H27N5O2SPureza:97.34%Forma y color:SolidPeso molecular:461.58JB300
CAS:<p>JB300 is a PROTAC-based compound that serves as a highly selective degrader of Aurora A, with a DC50 of 30 nM. It is utilized in cancer research. JB300 comprises the PROTAC target protein ligand MK-5108 [pink part], E3 ligase ligand Thalidomide-O-COOH [blue part], and PROTAC Linker Boc-NH-PEG2-C2-NH2 [black part]. The conjugate of the E3 ubiquitin ligase ligand and linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc.</p>Fórmula:C43H45ClFN7O10SForma y color:SolidPeso molecular:906.3755-Iminodaunorubicin
CAS:<p>5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.</p>Fórmula:C27H30N2O9Forma y color:SolidPeso molecular:526.546-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
<p>6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a purine nucleoside analogue with broad antitumor activity, particularly against</p>Fórmula:C10H15N7O4Forma y color:SolidPeso molecular:297.27IBU-DC Phosphoramidite
CAS:<p>IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.</p>Fórmula:C43H54N5O8PForma y color:SolidPeso molecular:799.9065'-O-TBDMS-dA
CAS:<p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C16H27N5O3SiForma y color:SolidPeso molecular:365.5095'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite
<p>5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.</p>Fórmula:C44H49F2N4O7PForma y color:SolidPeso molecular:814.85WAY-647802
CAS:<p>WAY-647802 is a CDK inhibitor.</p>Fórmula:C11H14N4O3Pureza:99.53%Forma y color:SolidPeso molecular:250.25Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Fórmula:C21H25FN4O2Forma y color:SolidPeso molecular:384.45Anticancer agent 263
<p>Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.</p>Fórmula:C13H20N2O6Forma y color:SolidPeso molecular:300.308N2-Acetylguanine
CAS:<p>Compound 19962-37-9, with CAS No. 19962-37-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound 19962-37-9 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C7H7N5O2Pureza:99.90%Forma y color:White SolidPeso molecular:193.166Obtustatin
<p>Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.</p>Fórmula:C184H284N52O57S8Pureza:98%Forma y color:SolidPeso molecular:4393.0713-TP
<p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>Fórmula:C12H19F2N6O12P3Forma y color:SolidPeso molecular:570.23CBP501 Affinity Peptide
CAS:<p>CBP501 Affinity Peptide, a Chk kinase inhibitor, disrupts G2 arrest triggered by DNA-damaging agents and is utilized in cancer research [1].</p>Fórmula:C68H119N21O25SForma y color:SolidPeso molecular:1662.86CDK2/4-IN-1
<p>CDK2/4-IN-1 (compound B-4a) serves as both a CDK2/4 inhibitor and a microtubule polymerization inhibitor, making it useful in cancer research.</p>Forma y color:Odour Solid2'-Deoxy-2'-fluoroguanosine 5'-monophosphate triethyl ammonium
<p>2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium, a purine nucleoside analog, exhibits broad antitumor activity specifically targeting indolent</p>Fórmula:C22H43FN7O7PForma y color:SolidPeso molecular:567.59Lysidine
CAS:<p>Lysidine (2-Methyl-2-iMidazoline) is a nucleoside rarely seen outside of tRNA. Lysidine has better translation fidelity.</p>Fórmula:C4H8N2Pureza:98%Forma y color:Light Yellow To Off-White CrystallinePeso molecular:84.12Dafsolimab
CAS:<p>Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is</p>Forma y color:LiquidCGP-74514
CAS:<p>CGP-74514,CDK1 inhibitor (IC50=25 nM). Induces G2/M arrest, apoptosis. Used in bladder cancer research.</p>Fórmula:C19H24ClN7Pureza:98.54%Forma y color:SoildPeso molecular:385.89DNA Gyrase-IN-17
<p>DNA Gyrase-IN-17 (Compound 5C) is an inhibitor of DNA gyrase. It demonstrates significant antimicrobial activity against a range of Gram-positive and Gram-negative strains, including Enterococcus faecium, Escherichia coli, and Pseudomonas aeruginosa, with a MIC value of 62.5 μg/mL. By inhibiting bacterial DNA gyrase, DNA Gyrase-IN-17 disrupts DNA replication. This compound can be useful in the development of antibiotics, particularly for studying resistant strains.</p>Fórmula:C18H15ClFN5OForma y color:SolidPeso molecular:371.094925'-O-DMT-rI
CAS:<p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>Fórmula:C31H30N4O7Forma y color:SolidPeso molecular:570.59N6-Methyladenine
CAS:<p>N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.</p>Fórmula:C6H7N5Pureza:99.78%Forma y color:SolidPeso molecular:149.15CDK9/EZH2-IN-1
CAS:<p>CDK9/EZH2-IN-1 is a dual-target inhibitor of CDK9 and EZH2 with IC50 values of 83.9 nM and 108.6 nM, respectively. It induces apoptosis and causes DNA double-strand breaks (DSB). Additionally, CDK9/EZH2-IN-1 inhibits the proliferation of MKN45, MDA-MB-453, and SW620 cancer cells, with respective IC50 values of 136.3 nM, 171.3 nM, and 315.7 nM.</p>Fórmula:C47H59N11O4S2Forma y color:SolidPeso molecular:906.17Pseudorabies virus-IN-1
<p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>Fórmula:C27H23ClF2N4O2Forma y color:SolidPeso molecular:508.947ONX 0801 trisodium
CAS:<p>ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.</p>Fórmula:C32H30N5Na3O10Forma y color:SolidPeso molecular:713.582'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine
<p>2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effective</p>Fórmula:C34H75FN9O12P3Forma y color:SolidPeso molecular:913.93P8RI acetate
<p>P8RI acetate mimics CD31, activates CDP8RI, and suppresses the immune response by restoring CD31 pathway.</p>Fórmula:C53H81N13O11Pureza:98.39%Forma y color:SolidPeso molecular:1076.29N6-Ethyl-2'-β-C-ethynyl adenosine
<p>N6-Ethyl-2’-beta-C-ethynyl adenosine is a purine nucleoside analog.</p>Fórmula:C14H17N5O4Forma y color:SolidPeso molecular:319.32Py-MAA-Val-Cit-PAB-DX8951
CAS:<p>Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].</p>Fórmula:C57H66FN11O13SForma y color:SolidPeso molecular:1164.26MS133
<p>MS133 is a human bispecific antibody targeting CD133/PROM1 and CD3E. It is used in the study of colon cancer.</p>Forma y color:Odour LiquidDitercalinium chloride
CAS:<p>Ditercalinium chloride, an anticancer agent, inhibits human DNA polymerase gamma activity and can deplete mitochondrial DNA in both mouse and human cells. Additionally, Ditercalinium chloride is a potential ligand against the COMMD10-AP3S1 fusion protein [1] [2].</p>Fórmula:C46H50Cl2N6O2Forma y color:SolidPeso molecular:789.83MAP3K5-IN-1
CAS:<p>Compound 7, also known as 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine, serves as an inhibitor of protein kinases, displaying IC50 values of 0.092 μM for PKC-α, 0.26 μM for ROCK, and 0.77 μM for ASK1. Additionally, this compound exhibits significant cytotoxicity towards PC-3 cancer cells, with an IC50 of 0.16 μM [1].</p>Fórmula:C28H24N4O4Forma y color:SolidPeso molecular:480.51A20FMDV2
CAS:<p>A20FMDV2 is a highly selective αvβ6 integrin inhibitor with an IC 50 of 3 nM, demonstrating 1,000-fold greater selectivity for αvβ6 compared to other RGD-directed integrins like αvβ3, αvβ5, and α5β1. This compound can be derived from the foot-and-mouth disease virus and is suitable for radiolabeling, enabling PET imaging of αvβ6 integrin-positive tumors.</p>Fórmula:C93H163N31O28Forma y color:SolidPeso molecular:2163.486-Thioguanosine
CAS:<p>6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside and low molecular weight gel.6-Thioguanosine has immunosuppressive properties.</p>Fórmula:C10H13N5O4SPureza:97.05%Forma y color:Yellow-Green PowderPeso molecular:299.31Integrin Binding Peptide
CAS:<p>Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.</p>Fórmula:C42H63N15O16SForma y color:SolidPeso molecular:1066.12PROTAC CDK9 degrader 4
CAS:<p>PROTAC CDK9 degrader 4 is a CDK9 degrader that targets transcriptional regulation and has potential anticancer activity.</p>Fórmula:C43H56N10O5Forma y color:SolidPeso molecular:792.97Filanesib TFA
CAS:<p>Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.</p>Fórmula:C22H23F5N4O4SPureza:98%Forma y color:SolidPeso molecular:534.5ML-60218
CAS:<p>ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.</p>Fórmula:C19H15Cl2N3O2S2Pureza:98.1%Forma y color:SolidPeso molecular:452.38N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
CAS:<p>N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].</p>Fórmula:C21H35N12O17P3Forma y color:SolidPeso molecular:820.49STX-100
<p>PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.</p>Pureza:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)Forma y color:Odour LiquidHEMTAC WEE1 degrader-1
CAS:<p>HEMTACWEE1degrader-1 is a WEE1-targeting heterobifunctional chimeric degrader (HEMTAC) facilitated by HSP90, exhibiting an HSP90 enzyme inhibitory activity with an IC50 of 16.76 nM. It enhances the ubiquitination and subsequent degradation of WEE1, effectively blocking the G2/M cell cycle transition. This compound shows anticancer properties in patient-derived xenograft (PDX) models of acute myeloid leukemia (AML). HEMTACWEE1degrader-1 is utilized in AML research.</p>Fórmula:C57H71N15O6Forma y color:SolidPeso molecular:1062.27TS-002266
CAS:<p>TS-0022666 is a selective TUT4/7 inhibitor, antiproliferative and anti-leukaemic in vivo and in vitro, cancers with FOCAD deficiency.</p>Fórmula:C31H32Cl2N6O5Pureza:98.18%Forma y color:SoildPeso molecular:639.53GSK-1070916
CAS:<p>GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM.</p>Fórmula:C30H33N7OPureza:99.73%Forma y color:SolidPeso molecular:507.63dAURK-4
CAS:<p>dAURK-4, a derivative of Alisertib, functions as a potent and selective degrader of AURKA (Aurora A), exhibiting anticancer properties [1].</p>Fórmula:C52H52ClFN8O12Forma y color:SolidPeso molecular:1035.473,6-DMAD hydrochloride
<p>3,6-DMAD hydrochloride functions as an inhibitor for the IRE1α-XBP1 pathway within the unfolded protein response mechanism.</p>Fórmula:C22H31N5xHClPureza:98%Forma y color:SolidPeso molecular:365.52DG1
<p>DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing</p>Fórmula:C19H17N5O5SForma y color:SolidPeso molecular:427.43Adenosine 5′-O-1-thiotriphosphate (disodium)
<p>Adenosine 5′-O-(1-thiotriphosphate) (disodium) is an adenosine nucleotide modified at the alpha-phosphate.</p>Fórmula:C10H14N5Na2O12P3SPeso molecular:566.93679MUS81-IN-1
<p>MUS81-IN-1 (compound 23) is an MUS81 inhibitor, utilized in cancer research.</p>Fórmula:C23H21N3O5Peso molecular:419.14812DHFR-IN-18
<p>DHFR-IN-18 (compound 19D) is a DHFR inhibitor utilized in leukemia-related research.</p>Fórmula:C24H22ClN7Peso molecular:443.16252dsDNase
<p>dsDNase is a highly specific endonuclease for double-stranded DNA (dsDNA) that can rapidly and efficiently eliminate contaminant DNA from PCR master mixes.</p>(Gly0.8Nap0.2)20
<p>(Gly0.8Nap0.2)20 is a dual-target compound effective against fungal membranes and DNA. It exhibits antimicrobial properties.</p>Fórmula:C139H236N38O24·16(C2F3O2)K34c hydrochloride
CAS:<p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>Fórmula:C26H30ClN3O4Pureza:99.76% - 99.89%Forma y color:SoildPeso molecular:483.995'-O-DMT-N2-DMF-dG
CAS:<p>5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.</p>Fórmula:C34H36N6O6Forma y color:SolidPeso molecular:624.698Lamifiban trifluoroacetate
CAS:<p>Lamifiban trifluoroacetate is an antagonist of the nonpeptide platelet fibrinogen receptor (GPIIb/IIIa).</p>Fórmula:C26H29F3N4O8Forma y color:SolidPeso molecular:582.533NUAK1-IN-1
<p>NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.</p>Fórmula:C25H30N6OForma y color:SolidPeso molecular:430.5457-TFA-ap-7-Deaza-ddA
CAS:<p>Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.</p>Fórmula:C16H16F3N5O3Forma y color:SolidPeso molecular:383.331CDK12/13-IN-2
<p>CDK12/13-IN-2 (Compound 24) is a covalent inhibitor of CDK12 and CDK13, exhibiting IC50 values of 15.5 nM and 12.2 nM, respectively. It effectively inhibits the proliferation of breast cancer cells and can be utilized in the research of triple-negative breast cancer.</p>Fórmula:C24H22FN7O2Forma y color:SolidPeso molecular:459.48USP7-IN-16
CAS:<p>USP7-IN-16 (Compound 61) is a selective inhibitor of USP7, with IC50 values of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. This compound exhibits antitumor activity in mice and holds potential for research in the field of oncology.</p>Fórmula:C43H45N7O6SForma y color:SolidPeso molecular:787.93PKMYT1-IN-6
<p>PKMYT1-IN-6 (compound 98) is an inhibitor of PKMYT1, exhibiting an IC50 of less than 50nM.</p>Forma y color:Odour SolidAV-153
CAS:<p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>Fórmula:C14H19NNaO6Forma y color:SolidPeso molecular:320.297N1-Benzoyl pseudouridine
<p>N1-Benzoyl pseudouridine, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.</p>Fórmula:C16H16N2O7Forma y color:SolidPeso molecular:348.314-Amino-1-(2-C-methyl-β-D-ribofuranosyl)-1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
CAS:<p>4-Amino-5-cyano-1-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine, a purine nucleoside analogue, exhibits widespread antitumor efficacy,</p>Fórmula:C13H15N5O4Forma y color:SolidPeso molecular:305.29ICAM-1988
CAS:<p>ICAM-1988 is a LFA-1 antagonist.</p>Fórmula:C22H22Cl2N4O6SForma y color:SolidPeso molecular:541.4DHFR-IN-11
<p>DHFR-IN-11 (compound 6b) is a DHFR inhibitor with demonstrated inhibitory efficacy against the M.</p>Forma y color:Odour SolidCW-2
<p>CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).</p>Fórmula:C43H42Cl2FN11O10PtForma y color:SolidPeso molecular:1156.21251PROTAC CDK9 degrader-5
CAS:<p>PROTAC CDK9 degrader-5 selectively degrades CDK9 isoforms 42, 55 with DC50 of 0.10μM, 0.14μM via proteasome.</p>Fórmula:C42H48Cl2N8O9Pureza:98%Forma y color:SolidPeso molecular:879.78Nusinersen
CAS:<p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>Pureza:98.62%Forma y color:Solid(S)-DI-87
CAS:<p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>Fórmula:C23H30N6O3S2Pureza:99.42%Forma y color:SoildPeso molecular:502.65Cdk2/Cyclin Inhibitory Peptide I
<p>CDK2, a Ser/Thr kinase, is akin to yeast cdc28 and human Cdk1, crucial for cell division.</p>Fórmula:C111H196N48O23Pureza:98%Forma y color:SolidPeso molecular:2571.05TS-002902
<p>TS-002902 is a small molecule inhibitor of TUT4/7, exhibiting antiproliferative activity. It holds potential for use in cancer research.</p>Forma y color:Odour Solid8-NH2-ATP
CAS:<p>8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.</p>Fórmula:C10H17N6O13P3Forma y color:SolidPeso molecular:522.20CDK8-IN-12
CAS:<p>CDK8-IN-12: selective CDK8 inhibitor (Ki 14 nM), oral anticancer, blocks GSK-3α/β, PCK-θ, halts MV4-11 cell growth.</p>Fórmula:C21H20ClN3O2Pureza:99.46% - 99.83%Forma y color:SoildPeso molecular:381.86HDAC-IN-85
<p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>Fórmula:C24H27FN4O5Forma y color:SolidPeso molecular:470.49YL-5092
<p>YL-5092 is an inhibitor of YT521-B homology (YTH) domain-containing protein 1 (YTHDC1). It inhibits acute myeloid leukemia cells with an IC50 of 0.28-2.87 μM. YL-5092 exhibits antitumor activity in xenograft mice models using MOLM-13 or U937 cells.</p>Fórmula:C22H14F3N3O2SForma y color:SolidPeso molecular:441.43Vanoxonin
CAS:<p>Vanoxonin is a new thymidylate synthetase inhibitor.</p>Fórmula:C18H25N3O9Pureza:98%Forma y color:SolidPeso molecular:427.41Guanosine triphosphate
CAS:<p>Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].</p>Fórmula:C10H16N5O14P3Forma y color:SolidPeso molecular:523.185'-ODMT cEt G Phosphoramidite (Amidite)
CAS:<p>5'-ODMT cEt G Amidite is a safe, effective nucleic acid analog with strong antisense activity.</p>Fórmula:C46H56N7O9PForma y color:SolidPeso molecular:881.95Cytarabine triphosphate
CAS:<p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>Fórmula:C9H16N3O14P3Forma y color:SolidPeso molecular:483.16FR901463
CAS:<p>FR 901463 is a biochemical.</p>Fórmula:C27H42ClNO8Forma y color:SolidPeso molecular:544.08LDV FITC
CAS:<p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>Fórmula:C69H81N11O17SPureza:98%Forma y color:SolidPeso molecular:1368.53PROTAC MPS1 degrader 2
<p>PROTAC MPS1 Degrader 2 (Compound 15) is a potent degrader of monopolar spindle 1 (Mps1, TTK), AURKA, and AURKB with DC50 values of 42.0, 2.1, and 154.0 nM respectively. It is utilized in the research of acute myeloid leukemia.</p>Fórmula:C41H41N11O8SForma y color:SolidPeso molecular:847.90Carboxy pyridostatin trifluoroacetate salt
<p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>Fórmula:C37H35F3N10O9Pureza:98%Forma y color:SolidPeso molecular:820.73dCeMM3
CAS:<p>dCeMM3 is a glue degrader that induces ubiquitination and degradation of cyclin K by promoting CDK12-cyclin K interaction with CRL4B ligase.</p>Fórmula:C14H11ClN4OSPureza:98.48% - 99.41%Forma y color:SolidPeso molecular:318.78DENV-IN-2
CAS:<p>DENV-IN-2 inhibits dengue virus replication (EC50: 0.016 nM), affects all serotypes (EC50: 0.013-0.029 nM). Derived from WO2018215315A1 6AB.</p>Fórmula:C29H26ClF3N2O6Forma y color:SolidPeso molecular:590.98TMX-2138
CAS:<p>TMX-2138 is a CDKs PROTAC degrader, with IC50 values of 8.7 nM for CDK1/cyclinB, 10.9 nM for CDK2/cyclinA, 7.0 nM for CDK5/p25, and 25.7 nM for CDK9/cyclinT1. It enhances the ubiquitination and degradation of CDKs and is utilized for ovarian cancer research.</p>Fórmula:C40H43BrFN9O11SForma y color:SolidPeso molecular:956.791Uridine triphosphate 13C9,15N2 sodium
CAS:<p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>Fórmula:C9H1415N2NaO15P3Forma y color:SolidPeso molecular:517.04Activated Protein C (390-404), human TFA
<p>APC's 390-404 peptide region key to anticoagulation, binds antibodies/proteins, inactivates cofactors Va/VIIIa.</p>Fórmula:C93H131F3N22O25Pureza:98%Forma y color:SolidPeso molecular:2014.165-Caroxy uracil-1-yl acetic acid benzyl ester
<p>5-Caroxy uracil-1-yl acetic acid benzyl ester, a purine analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.</p>Fórmula:C14H12N2O6Forma y color:SolidPeso molecular:304.25Etrolizumab
CAS:<p>MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.</p>Pureza:98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)Forma y color:LiquidBesufetamig
CAS:<p>Besufetamig is a bispecific antibody targeting programmed cell death protein 1 (PD-1) and the CD3ε chain. It modulates immune cell activity, exerting both immunosuppressive and antitumor effects. Besufetamig holds promise for cancer research.</p>Forma y color:Liquid2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS:<p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>Fórmula:C10H14N5Na2O8PForma y color:SolidPeso molecular:409.202DSPE-PEG1000-cRGD
<p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>Forma y color:Odour SolidCDK9-IN-25
<p>CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM.</p>Fórmula:C15H16FN5Pureza:98%Forma y color:SolidPeso molecular:285.32Risuteganib
CAS:<p>Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide that regulates the functions of multiple integrin isoforms.</p>Fórmula:C22H39N9O11SPureza:98%Forma y color:SolidPeso molecular:637.66TH1085
CAS:<p>TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).</p>Fórmula:C17H21N3Pureza:99.99%Forma y color:SolidPeso molecular:267.37DHODH-IN-16
CAS:<p>DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).</p>Fórmula:C24H25FN4O3Pureza:99.64%Forma y color:SolidPeso molecular:436.487-TFA-ap-7-Deaza-ddG
CAS:<p>Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.</p>Fórmula:C16H16F3N5O4Forma y color:SolidPeso molecular:399.33Cotylenin A
CAS:<p>Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.</p>Fórmula:C33H50O11Forma y color:SolidPeso molecular:622.744Erythromycin A dihydrate
CAS:<p>Erythromycin dihydrate, a macrolide antibiotic from Streptomyces erythreus, targets 50S ribosomal subunits, blocking protein synthesis.</p>Fórmula:C37H69NO14Forma y color:SolidPeso molecular:751.94CDK2-IN-7
CAS:<p>CDK2-IN-7 is a CDK2 inhibitor for treating cancer ( IC 50 < 50 nM).</p>Fórmula:C24H30N6O4SForma y color:SolidPeso molecular:498.6wrwycr-NH2 TFA
<p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>Forma y color:Odour SolidEmicoron
CAS:<p>Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.</p>Fórmula:C52H58N6O4Pureza:98%Forma y color:SolidPeso molecular:831.055'-DMT-3'-TBDMS-Bz-rA
CAS:<p>5'-DMT-3'-TBDMS-Bz-rA is a nucleoside with protective and modification effects.</p>Fórmula:C44H49N5O7SiForma y color:SolidPeso molecular:787.975-O-benzoyl-1,2-O-isopropylidene-α-D-erythro-pent-3-ulofuranose
CAS:<p>5-O-benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose is a Carbohydrate; Used for modified nucleoside.</p>Fórmula:C15H16O6Forma y color:SolidPeso molecular:292.282',3'-Dideoxy-3'-fluorouridine
CAS:<p>Nucleoside Derivatives - 2’,3’-Dideoxy nucleosides, Fluoro-modified nucleosides, 3’-Modified nucleosides; Drugs and Inhibitors; Anti-HIV agent</p>Fórmula:C9H11FN2O4Forma y color:SolidPeso molecular:230.193'-O-(2-Azidoethyl)adenosine
<p>Nucleoside Derivatives - 3’-Modified nucleosides; Azido-nucleosides</p>Forma y color:Soild3'-O-t-Bulyldimethylsilyl thymidine
CAS:<p>Nucleosides - 2’-deoxynucleoside</p>Fórmula:C16H28N2O5SiForma y color:SolidPeso molecular:356.492'-Deoxy-2'-fluoro-b-D-arabino-6-azauridine
CAS:<p>2'-Deoxy-2'-fluoro-b-D-arabino-6-azauridine is a Nucleoside Derivative - 6-Aza-uridine; Fluoro-modified nucleoside; Arabino nucleoside.</p>Fórmula:C8H10FN3O5Forma y color:SolidPeso molecular:247.18N6-Acetyl adenosine
CAS:<p>Nucleoside Derivatives –Naturally modified ribo-nucleosides;Other modified nucleosides</p>Fórmula:C12H15N5O5Forma y color:SolidPeso molecular:309.28N1-Methyl-2'-deoxy-2'-fluoroarabinoadenosine
<p>N1-Methyl-2'-deoxy-2'-fluoroarabinoadenosine is a Nucleoside Derivative - 2'-Modified nucleoside, N-Methylated/alkylated nucleoside, Fluoro-modified nucleoside.</p>Forma y color:Soild2'-O-(2-Methoxyethyl) inosine
CAS:<p>2'-O-(2-Methoxyethyl) inosine is a Nucleoside Derivative - 2'-Modified nucleoside.</p>Fórmula:C13H18N4O6Forma y color:SolidPeso molecular:326.312'-O-Acetyl-3'-azido-5'-O-(p-Toluoyl))-3'-deoxyuridine
CAS:<p>Nucleoside Derivatives - 3’-Modified nucleoside, Azido-nucleosides</p>Fórmula:C19H19N5O7Forma y color:SolidPeso molecular:429.382'-β-C-Methyl inosine
CAS:<p>2'-beta-C-Methyl inosine (2'-C-Methyl inosine) is an HCV RNA polymerase inhibitor with antiviral activity and may be used in studies to treat hcv infections.</p>Fórmula:C11H14N4O5Forma y color:SolidPeso molecular:282.252'-Deoxy-5,N4-dimethylcytidine
CAS:<p>2'-Deoxy-5,N4-dimethylcytidine is a Nucleoside Derivative - N-Methylated nucleoside.</p>Fórmula:C11H17N3O4Forma y color:SolidPeso molecular:255.275-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine
CAS:<p>Nucleoside Derivatives - C-Nucleosides, Pyridine nucleosides</p>Fórmula:C39H39NO5Forma y color:SolidPeso molecular:601.736-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine
CAS:<p>6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine is a Nucleoside Derivative - Other modified nucleoside.</p>Fórmula:C10H13N5O3Forma y color:SolidPeso molecular:251.248-Nitroguanosine
CAS:<p>8-Nitroguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.</p>Fórmula:C10H12N6O7Forma y color:SolidPeso molecular:328.243'-deoxy-3'-fluoro-β-D-xylo-inosine
CAS:<p>Nucleoside Derivatives - Fluoro-modified nucleosides; 3’-Modified nucleosides; Xylo-nucleosides</p>Fórmula:C10H11FN4O4Forma y color:SolidPeso molecular:270.222'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-fluorouridine
CAS:<p>2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-fluorouridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 5-modified pyrimidine nucleoside, 3'-</p>Fórmula:C19H18F2N2O7Forma y color:SolidPeso molecular:424.352'-Deoxy-2'-fluoro-5-hydroxymethyl arabinouridine
CAS:<p>Nucleoside Derivatives - Fluoro-modified nucleosides; 2’-Modified nucleosides; 5-Modified pyrimidine nucleosides; Metabolite of FMAU</p>Fórmula:C10H13FN2O6Forma y color:SolidPeso molecular:276.222'-Deoxy-6-azauridine
CAS:<p>2’-Deoxy-6-azauridine is a useful organic compound for research related to life sciences. The catalog number is TNU1081 and the CAS number is 20500-29-2.</p>Fórmula:C8H11N3O5Forma y color:SolidPeso molecular:229.192',3',5'-Tri-O-Benzoyl-4'-thiouridine
CAS:<p>2',3',5'-Tri-O-Benzoyl-4'-thiouridine is a Thio-nucleoside.</p>Fórmula:C30H24N2O8SForma y color:SolidPeso molecular:572.593'-O-t-Butyldimethylsilyl adenosine
CAS:<p>3'-O-t-Butyldimethylsilyl adenosine is a Nucleoside; Used for special nucleoside modification.</p>Fórmula:C16H27N5O4SiForma y color:SolidPeso molecular:381.56-Deoxo-8-oxo-3'-deoxy-guanosine
<p>6-Deoxo-8-oxo-3’-deoxy-guanosine is a useful organic compound for research related to life sciences and the catalog number is TNU1451.</p>Forma y color:Soild(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol
CAS:<p>(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is a Nucleoside Derivative - C-nucleoside; Fluoro-modified nucleoside.</p>Fórmula:C11H12F2O4Forma y color:SolidPeso molecular:246.21DMTr-LNA-G(iBu)-3'-CED-phosphoramidite
CAS:<p>Nucleoside Derivatives - LNA-related nucleosides; Nucleoside Phosphoramidites</p>Fórmula:C45H54N7O9PForma y color:SolidPeso molecular:867.935-(Aminomethyl)-2-thiouridine
CAS:<p>Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Thio-nucleosides; Amino nucleosides; Naturally modified ribo-nucleosides</p>Fórmula:C10H15N3O5SForma y color:SolidPeso molecular:289.31N6-Methyl-xylo-adenosine
CAS:<p>N6-Methyl-xylo-adenosine is a Nucleoside Derivative - Xylo-nucleoside;6-Substituted purine nucleoside.</p>Fórmula:C11H15N5O4Forma y color:SolidPeso molecular:281.272-Deoxy-2'-deoxyuridine
CAS:<p>2-Deoxy-2'-deoxyuridine is a Nucleoside Derivative - 2-Deoxy uridine.</p>Fórmula:C9H12N2O4Forma y color:SolidPeso molecular:212.22-Methoxy-2'-deoxyadenosine
CAS:<p>2-Methoxy-2'-deoxyadenosine is a Nucleoside Derivative - 2-Modified purine nucleoside.</p>Fórmula:C11H15N5O4Forma y color:SolidPeso molecular:281.272'-Deoxy-2'-iodouridine
CAS:<p>2'-Deoxy-2'-iodouridine is a Halo-nucleoside.</p>Fórmula:C9H11IN2O5Forma y color:SolidPeso molecular:354.1DHPS-IN-1
CAS:<p>DHPS-IN-1, a chemical compound, demonstrates exceptional inhibitory potency against melanoma cells, as evidenced by its IC50 value of 0.014 μM.</p>Fórmula:C17H13BrClN3O2Forma y color:SolidPeso molecular:406.668-Chloroguanosine
CAS:<p>8-Chloroguanosine is a Nucleoside Derivative - Halo-nucleoside, 8-Modified purine nucleoside.</p>Fórmula:C10H12ClN5O5Forma y color:SolidPeso molecular:317.69
![4-Amino-1-(2-C-methyl-β-D-ribofuranosyl)-1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT75076.webp&w=3840&q=75)
![6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTNU1427.webp&w=3840&q=75)
