Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(115 productos)
- CDK(547 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(46 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(269 productos)
- Kinesina(87 productos)
- LIM quinasa(21 productos)
- Asociado a microtúbulos(273 productos)
- PKC(127 productos)
- PLK(25 productos)
- ROCK(61 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3912 productos de "Ciclo celular / Checkpoint"
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N6-Benzoylarabinoadenosine
CAS:Nucleoside Derivatives - Arabino-nucleosidesFórmula:C17H17N5O5Forma y color:SolidPeso molecular:371.35Ref: TM-TNU0951
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar4'-C-Methyl-5-methoxyuridine
CAS:Nucleoside Derivatives - 4’-Modified nucleosides; 5-Modified pyrimidine nucleosidesFórmula:C11H16N2O7Forma y color:SolidPeso molecular:288.25Ref: TM-TNU0403
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2-Amino-6-chloropurine-3',5'-di-O-acetyl-2'-deoxyriboside
CAS:Nucleoside - 2’-deoxy nucleoside; halo nucleosideFórmula:C14H16ClN5O5Forma y color:SolidPeso molecular:369.76Ref: TM-TNU0719
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar5-Bromoarabinouridine
CAS:5-Bromoarabinouridine is a Halo-nucleoside; Arabino-nucleoside.Fórmula:C9H11BrN2O6Forma y color:SolidPeso molecular:323.1Ref: TM-TNU0785
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2',3',5'-Tri-O-acetyl-2-thiouridine
CAS:Nucleosides Derivatives –Thio-nucleosidesFórmula:C15H18N2O8SForma y color:SolidPeso molecular:386.38Ref: TM-TNU0858
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine
CAS:Nucleoside Derivatives - Fluoro-Modified nucleosides, 2’-Modified nucleosides; Protected nucleosides with NH2/OH groupFórmula:C15H25FN2O5SiForma y color:SolidPeso molecular:360.45Ref: TM-TNU0943
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN2-iso-Butyroyl-2'-O-propargylguanosine
CAS:N2-iso-Butyroyl-2'-O-propargylguanosine is a Nucleoside Derivative - 2'-Modified nucleoside.Fórmula:C17H21N5O6Forma y color:SolidPeso molecular:391.38Ref: TM-TNU0938
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN1-Methyl-2'-deoxyadenosine
CAS:Nucleoside Derivatives - N-Methylated/ alkylated nucleosides; DNA adductFórmula:C11H15N5O3Forma y color:SolidPeso molecular:265.27Ref: TM-TNU1220
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN2-[(N,N-Dimethyl)amino]methylene-N1-methyl-2'-O-Methyl guanosine
CAS:Nucleoside Derivatives - 2’-Modified nucleosides; N-Alkylated nucleosidesFórmula:C15H22N6O5Forma y color:SolidPeso molecular:366.37Ref: TM-TNU0499
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar8-Azido-2'-deoxyadenosine
CAS:Nucleoside Derivatives - 8-Modified purine nucleosides; Azido nucleosidesFórmula:C10H12N8O3Forma y color:SolidPeso molecular:292.25Ref: TM-TNU1241
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar4'-Methyl-5-methyluridine
CAS:Nucleoside Derivatives - 4’-Modified nucleosides, 5-Modified pyrimidine nucleosidesFórmula:C11H16N2O6Forma y color:SolidPeso molecular:272.25Ref: TM-TNU0246
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Deoxy-2'-fluoro-N3-(4-hydroxybenzyl)uridine
2'-Deoxy-2'-fluoro-N3-(4-hydroxybenzyl)uridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 2'-Modified nucleoside.Forma y color:SoildRef: TM-TNU0764
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar4,6-Diamino-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
CAS:Nucleoside Derivatives - 8-Aza-7-deaza-purine nucleoside; 2-Modified purine nucleosideFórmula:C10H14N6O4Forma y color:SolidPeso molecular:282.26Ref: TM-TNU0280
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-O-Phthalimidopropyl uridine
CAS:2’-O-Phthalimidopropyl uridine is a useful organic compound for research related to life sciences.Fórmula:C20H21N3O8Forma y color:SolidPeso molecular:431.4Ref: TM-TNU1664
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar4'-Cyanouridine
CAS:4'-Cyanouridine is a Nucleoside Derivative - 4'-Modified nucleoside.Fórmula:C10H11N3O6Forma y color:SolidPeso molecular:269.21Ref: TM-TNU0209
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN6-Ethyl-2'-O-methyladenosine
CAS:N6-Ethyl-2'-O-methyladenosine is a Nucleoside Derivative - 6-Modified purine nucleoside, 2'-Modified nucleoside.Fórmula:C13H19N5O4Forma y color:SolidPeso molecular:309.32Ref: TM-TNU0592
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar5-Benzylaminocarbony-3'-O-Ac-2'-O-Me-5'-O-DMT-uridine
CAS:5-Benzylaminocarbony-3'-O-Ac-2'-O-Me-5'-O-DMT-uridine is a 5 modified pyrimidine nucleoside; 2'-O-Methyl nucleoside.Fórmula:C41H41N3O10Forma y color:SolidPeso molecular:735.78Ref: TM-TNU0655
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2',3'-Dideoxy-2',3'-didehydro-uridine
CAS:Nucleoside Derivatives - Didehydro-nucleosideFórmula:C9H10N2O4Forma y color:SolidPeso molecular:210.19Ref: TM-TNU0994
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3-epi-Azido-3-deoxythymidine
CAS:3’-N-modified nucleoside; Azido-nucleosideFórmula:C10H13N5O4Forma y color:SolidPeso molecular:267.24Ref: TM-TNU0789
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar1-(b-D-Xylofuranosyl)-5-methyluracil
CAS:1-(b-D-Xylofuranosyl)-5-methyluracil is a Nucleoside Derivative - Xylo-nucleoside.Fórmula:C10H14N2O6Forma y color:SolidPeso molecular:258.23Ref: TM-TNU0265
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar5-Methoxy-4'-thiouridine
Nucleoside Derivatives - Thio-nucleosides; 5-Modified pyrimidine nucleosidesForma y color:SoildRef: TM-TNU0152
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN2-iso-Butyroyl-5'-O-DMT-3'-O-(methoxyethyl)guanosine
CAS:N2-iso-Butyroyl-5'-O-DMT-3'-O-(methoxyethyl)guanosine is a Nucleoside Derivative - 3'-Modified nucleoside; Protected nucleoside w/NH2/OH open.Fórmula:C38H43N5O9Forma y color:SolidPeso molecular:713.78Ref: TM-TNU1390
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN6-Benzoyl-2'-O-methyladdenosine
CAS:N6-Benzoyl-2'-O-methyladdenosine is a 2'-O-Methyl nucleoside.Fórmula:C18H19N5O5Forma y color:SolidPeso molecular:385.37Ref: TM-TNU0704
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3'-Deoxy-3'-fluorouridine
CAS:3'-Deoxy-3'-fluorouridine is a nucleoside, fluoro-modified nucleoside.Fórmula:C9H11FN2O5Forma y color:SolidPeso molecular:246.19Ref: TM-TNU0004
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3'-β-Azido-2',3'-dideoxy-5'-O-(4-methoxytrityl)uridine
CAS:3'-beta-Azido-2',3'-dideoxy-5'-O-(4-methoxytrityl)uridine is a Nucleoside Derivative - 2',3'-Dideoxy nucleoside, 3'-Modified nucleoside, Azido-nucleoside, Xylo-Fórmula:C29H27N5O5Forma y color:SolidPeso molecular:525.56Ref: TM-TNU0926
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2′-Deoxy-6-thioinosine
CAS:2'-Deoxy-6-thioinosine is a Nucleoside Derivative - Thio-nucleoside.Fórmula:C10H12N4O3SForma y color:SolidPeso molecular:268.29Ref: TM-TNU0979
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN2-(Isopropylphenoxyacetyl)-2'-O-propargylguanosine
CAS:Nucleoside Derivatives - 2’-Modifed NucleosidesFórmula:C24H27N5O7Forma y color:SolidPeso molecular:497.5Ref: TM-TNU0918
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar8-Hydroxy-3'-deoxyguanosine
Nucleoside Derivatives - 3’-Deoxy-nucleosides; 8-Modified purine nucleosidesForma y color:SoildRef: TM-TNU0447
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2',3'-Dideoxy-3'-fluoroadenosine
CAS:Nucleoside Derivatives - Fluoro-modified nucleosides; 2’,3’-Dideoxy nucleosides; Drugs and Inhbitors; Antiviral agentFórmula:C10H12FN5O2Forma y color:SolidPeso molecular:253.23Ref: TM-TNU1248
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarLY3143921
CAS:LY3143921 ((S)-Example 2) is an orally active inhibitor of CDC7 kinase with broad in vitro anticancer activity [1].Fórmula:C16H12FN5OForma y color:SolidPeso molecular:309.3Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Fórmula:C27H41N9O7Pureza:95.29% - >99.99%Forma y color:SolidPeso molecular:603.67TCS7010
CAS:TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.Fórmula:C31H31ClFN7O2Pureza:98.49% - 99.62%Forma y color:SolidPeso molecular:588.07MSC2530818
CAS:MSC2530818 is an effective, selective and orally available CDK8 inhibitor (IC50: 2.6 nM).Fórmula:C18H17ClN4OPureza:98.93%Forma y color:SolidPeso molecular:340.81Ref: TM-TQ0266
1mg63,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg462,00€50mg692,00€100mg964,00€MLCK inhibitor peptide 18 acetate
MLCK inhibitor peptide 18 acetate: Selective (IC50=50nM), 4000x more than CaM kinase II. Does not block PKA. Cell-permeable.Fórmula:C62H109N23O13Pureza:99.57%Forma y color:SolidPeso molecular:1384.67R-IMPP
CAS:R-IMPP is an inhibitor of PCSK9 translation.Fórmula:C24H27N3O2Pureza:99.47% - 99.85%Forma y color:SolidPeso molecular:389.49Ref: TM-T4058
1mg46,00€2mg56,00€1mL*10mM (DMSO)75,00€5mg88,00€10mg140,00€25mg280,00€50mg500,00€100mg718,00€CID44216842
CAS:CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Fórmula:C22H20BrN3O3SPureza:99.66%Forma y color:SolidPeso molecular:486.38Ref: TM-T8930
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg85,00€25mg159,00€50mg244,00€100mg359,00€200mg512,00€Tegafur-Uracil
CAS:Tegafur-Uracil, an oral anticancer agent for solid tumor research, inhibits thymidylate synthase.Fórmula:C12H13FN4O5Forma y color:SolidPeso molecular:312.257Levoleucovorin Calcium
CAS:Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant.Fórmula:C20H21N7O7·CaPureza:99.07% - ≥98%Forma y color:White Crystalline PowderPeso molecular:511.5Deoxythymidine triphosphate
CAS:Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.Fórmula:C10H17N2O14P3·XNaPureza:99.78%Forma y color:White Amorphous PowderPeso molecular:482.17（free base）BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Fórmula:C21H20N4O2Pureza:99.47% - 99.84%Forma y color:SolidPeso molecular:360.41Afuresertib
CAS:Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplasticFórmula:C18H17Cl2FN4OSPureza:97.51% - 99.51%Forma y color:SolidPeso molecular:427.32Ref: TM-T1911
1mg37,00€2mg52,00€5mg74,00€1mL*10mM (DMSO)74,00€10mg92,00€25mg166,00€50mg259,00€100mg452,00€500mg982,00€Danofloxacin
CAS:Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.Fórmula:C19H20FN3O3Pureza:99.77% - 99.8%Forma y color:SolidPeso molecular:357.38TCID
CAS:TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.Fórmula:C9H2Cl4O2Pureza:99.34%Forma y color:SolidPeso molecular:283.92GNE-6640
CAS:GNE-6640: non-covalent USP7 inhibitor; IC50s: 0.75 µM (full), 0.43 µM (catalytic), 20.3 µM (USP43), 0.23 µM (Ub-MDM2).Fórmula:C20H18N4OPureza:98.64%Forma y color:SolidPeso molecular:330.38Ref: TM-T5461
1mg66,00€2mg96,00€5mg144,00€1mL*10mM (DMSO)158,00€10mg236,00€25mg507,00€50mg730,00€100mg1.018,00€CC-671
CAS:CC-671 is a dual TTK protein kinase (IC50: 0.005 μM) /CLK2 (IC50: 0.006 μM) inhibitor.Fórmula:C28H28N6O4Pureza:98.66% - 98.8%Forma y color:SolidPeso molecular:512.56Ref: TM-T4482
1mg50,00€5mg105,00€1mL*10mM (DMSO)120,00€10mg170,00€25mg340,00€50mg512,00€100mg733,00€500mg1.513,00€TH5487
CAS:TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)Fórmula:C19H18BrIN4O2Pureza:98.38% - 98.73%Forma y color:SolidPeso molecular:541.18Simeprevir sodium
CAS:Simeprevir is a drug for the treatment and cure of hepatitis C.Fórmula:C38H46N5NaO7S2Pureza:98%Forma y color:SolidPeso molecular:771.92CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Fórmula:C22H23Cl2N7Pureza:96.2% - 99.81%Forma y color:SolidPeso molecular:456.37ZM-447439
CAS:ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Fórmula:C29H31N5O4Pureza:99.11% - 99.59%Forma y color:Pale Yellow SolidPeso molecular:513.593'-Deoxyguanosine
CAS:3'-Deoxyguanosine is a ligand that can be complexed with enzymes, such as purine nucleoside phosphorylase, and receptors.Fórmula:C10H13N5O4Pureza:98.85% - 98.96%Forma y color:SolidPeso molecular:267.24
![N2-[(N,N-Dimethyl)amino]methylene-N1-methyl-2'-O-Methyl guanosine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTNU0499.webp&w=3840&q=75)
![4,6-Diamino-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTNU0280.webp&w=3840&q=75)
