Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(115 productos)
- CDK(547 productos)
- Detención del ciclo celular(5 productos)
- Chk(48 productos)
- DYRK(47 productos)
- Dynamin(27 productos)
- Ferroptosis(227 productos)
- HSP(180 productos)
- Integrin(269 productos)
- Kinesina(87 productos)
- LIM quinasa(20 productos)
- Asociado a microtúbulos(273 productos)
- PKC(126 productos)
- PLK(25 productos)
- ROCK(62 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(76 productos)
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Se han encontrado 3909 productos de "Ciclo celular / Checkpoint"
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4'-C-Methyl-2-thiouridine
CAS:Nucleoside Derivatives - 4’-Modified nucleosides; Thio-nucleosidesFórmula:C10H14N2O5SForma y color:SolidPeso molecular:274.29Ref: TM-TNU0406
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarRef: TM-TNU0736
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2',3'-Dideoxyuridine
CAS:2',3'-Dideoxyuridine is a purine nucleoside analog with potential antitumor activity.Fórmula:C9H12N2O4Pureza:99.76%Forma y color:SolidPeso molecular:212.22'-β-C-Ethynyladenosine
CAS:2'-β-C-Ethynyladenosine is a nucleoside analog that potently inhibits hepatitis C virus (HCV) replication by targeting the viral NS5B polymerase.Fórmula:C12H13N5O4Forma y color:SolidPeso molecular:291.26GDC-0425
CAS:GDC-0425 (RG-7602), an oral selective ChK1 inhibitor, targets multiple cancers.Fórmula:C18H19N5OForma y color:SolidPeso molecular:321.383'-O-Acetylthymidine
CAS:3'-O-Acetylthymidine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.Fórmula:C12H16N2O6Forma y color:SolidPeso molecular:284.27Ref: TM-TNU1559
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN1-Methyl ara-uridine
CAS:Nucleoside Derivatives –Arabino-nucleosides, N-Methylated/ alkylated nucleosidesFórmula:C10H14N2O6Forma y color:SolidPeso molecular:258.23Ref: TM-TNU1556
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3',5'-Di-O-acetyl-2'-deoxy-N3-methyl uridine
CAS:3',5'-Di-O-acetyl-2'-deoxy-N3-methyl uridine is a Nucleoside Derivative - N-Alkylated nucleoside.Fórmula:C14H18N2O7Forma y color:SolidPeso molecular:326.3Ref: TM-TNU1398
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3'-β-C-Methyl-5-methylcytidine
3'-beta-C-Methyl-5-methylcytidine is a Nucleoside Derivative - 3'-Modified nucleoside.Forma y color:SoildRef: TM-TNU0528
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN4-Benzoyl-3'-O-(2-methoxyethyl)-5-methylcytidine
N4-Benzoyl-3'-O-(2-methoxyethyl)-5-methylcytidine is a Nucleoside Derivative - 3'-Modified nucleoside.Forma y color:SoildRef: TM-TNU1361
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-O-Phthalimidopropyl cytidine
CAS:2’-O-Phthalimidopropyl cytidine is a useful organic compound for research related to life sciences.Fórmula:C20H22N4O7Forma y color:SolidPeso molecular:430.41Ref: TM-TNU1660
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3'-Deoxy-5-methoxyuridine
CAS:Nucleoside Derivatives - 3’-Deoxy nucleosides, 5-Modified pyrimidine nucleosidesFórmula:C10H14N2O6Forma y color:SolidPeso molecular:258.23Ref: TM-TNU0253
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Chloro-2'-deoxyuridine
CAS:2'-Chloro-2'-deoxyuridine is a Halo-nucleoside.Fórmula:C9H11ClN2O5Forma y color:SolidPeso molecular:262.65Ref: TM-TNU0073
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-β-C-Ethynyl inosine
CAS:2'-beta-C-Ethynyl inosine is a Nucleoside Derivative - 2'-Modified nucleoside.Fórmula:C12H12N4O5Forma y color:SolidPeso molecular:292.25Ref: TM-TNU0583
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN3-(Butyn-3-yl)uridine
N3-(Butyn-3-yl)uridine is a Nucleoside Derivative - Other modified nucleoside.Forma y color:SoildRef: TM-TNU0738
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN6-Benzoyl-2'-chloro-2'-deoxyadenosine
CAS:N6-Benzoyl-2'-chloro-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2'-Modified nucleoside.Fórmula:C17H16ClN5O4Forma y color:SolidPeso molecular:389.79Ref: TM-TNU1084
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine
CAS:N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)] propylpseudouridine is a Nucleoside Derivative - C-nucleoside; N-Alkylated nucleoside.Fórmula:C23H37N3O10Forma y color:SolidPeso molecular:515.55Ref: TM-TNU0078
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarα-inosine
CAS:Alpha-inosine is a useful organic compound for research related to life sciences. The catalog number is TNU1638 and the CAS number is 38183-47-0.Fórmula:C10H12N4O5Forma y color:SolidPeso molecular:268.23Ref: TM-TNU1638
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3'-Azido-3'-deoxyadenosine
CAS:3'-Azido-3'-deoxyadenosine is a Azido-nucleoside; 3'-N-Modified nucleoside.Fórmula:C10H12N8O3Forma y color:SolidPeso molecular:292.25Ref: TM-TNU0147
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine
CAS:3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine is a Nucleoside, fluoro-modified nucleoside, halo-nucleoside.Fórmula:C13H14FIN2O7Forma y color:SolidPeso molecular:456.16Ref: TM-TNU0623
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2-Deoxy-2'-deoxy-5'-(4,4'-dimethoxytrityl)uridine
CAS:Nucleoside Derivatives - 2-Deoxy uridines, Protected nucleosides with NH2/OH openFórmula:C30H30N2O6Forma y color:SolidPeso molecular:514.57Ref: TM-TNU1565
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)uridine
2'-Deoxy-2'-fluoro-N3-(4-nitrobenzyl)uridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 2'-Modified nucleoside.Forma y color:SoildRef: TM-TNU0761
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarTCRS-417
CAS:TCRS-417 (T417) inhibits PBX1-DNA interaction in mammalian cells or cell clusters, used in autoimmune and neurodegenerative disease research.Fórmula:C25H19FN2O5Forma y color:SolidPeso molecular:446.433',5'-TIPS-N-Ac-Adenosine
CAS:3',5'-TIPS-N-Ac-Adenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.Fórmula:C24H41N5O6Si2Forma y color:SolidPeso molecular:551.78Ref: TM-TNU1200
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarN3-Methyl-2'-O-(2-methoxyethyl)uridine
CAS:N3-Methyl-2'-O-(2-methoxyethyl)uridine is a Nucleoside Derivative - N-Methylated nucleoside.Fórmula:C13H20N2O7Forma y color:SolidPeso molecular:316.31Ref: TM-TNU0375
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultar3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-5-methyl-β-D-arabinouridine
CAS:Nucleoside Derivatives –Fluoro-modified nucleosides, 5-Modified pyrimidine nucleosides, Arabino-nucleosides, 2’-Modified nucleosidesFórmula:C24H21FN2O7Forma y color:SolidPeso molecular:468.43Ref: TM-TNU0865
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarα-Uridine
CAS:alpha-Uridine is a useful organic compound for research related to life sciences. The catalog number is TNU1635 and the CAS number is 3258-07-9.Fórmula:C9H12N2O6Forma y color:SolidPeso molecular:244.22'-Deoxy-5,N4,N4-trimethylcytidine
CAS:2'-Deoxy-5,N4,N4-trimethylcytidine is a Nucleoside Derivative - N-Methylated nucleoside.Fórmula:C12H19N3O4Forma y color:SolidPeso molecular:269.3Ref: TM-TNU1209
5mgA consultar10mgA consultar25mgA consultar50mgA consultar100mgA consultar500mgA consultarAZ3146
CAS:AZ3146 is a selective Mps1 inhibitor with IC50 of ~35 nM.Fórmula:C24H32N6O3Pureza:97.84% - >99.99%Forma y color:SolidPeso molecular:452.55Rabusertib
CAS:Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.
Fórmula:C18H22BrN5O3Pureza:98.86% - 99.87%Forma y color:SolidPeso molecular:436.3ZM-447439
CAS:ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.Fórmula:C29H31N5O4Pureza:99.11% - 99.59%Forma y color:Pale Yellow SolidPeso molecular:513.596-Mercaptopurine hydrate
CAS:6-Mercaptopurine hydrate is a leukemia treatment; it blocks purine metabolism, affecting DNA synthesis.Fórmula:C5H6N4OSPureza:97.54% - 99.14%Forma y color:Light Yellow Crystalline PowderPeso molecular:170.19iRGD peptide
CAS:iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Fórmula:C35H57N13O14S2Pureza:98.77%Forma y color:SolidPeso molecular:948.04BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Fórmula:C21H20N4O2Pureza:99.47% - 99.84%Forma y color:SolidPeso molecular:360.41TH287
CAS:TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.Fórmula:C11H10Cl2N4Pureza:97.73% - 99%Forma y color:SolidPeso molecular:269.13Ref: TM-T2069
1mg37,00€2mg48,00€5mg72,00€1mL*10mM (DMSO)79,00€10mg96,00€25mg188,00€50mg366,00€100mg545,00€Pyrintegrin
CAS:Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.Fórmula:C23H25N5O3SPureza:99.19%Forma y color:SolidPeso molecular:451.54Ref: TM-T16695
1mg78,00€2mg90,00€5mg150,00€1mL*10mM (DMSO)165,00€10mg215,00€25mg385,00€50mg595,00€100mg858,00€Senexin B
CAS:Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).Fórmula:C27H26N6OPureza:99.67%Forma y color:SolidPeso molecular:450.53Ref: TM-T8430
1mg92,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg260,00€25mg401,00€50mg532,00€100mg708,00€200mg964,00€Leukadherin-1
CAS:Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Fórmula:C22H15NO4S2Pureza:98.49% - 98.93%Forma y color:SolidPeso molecular:421.49Camostat mesylate
CAS:Camostat mesylate (FOY-S980) is a trypsin-like protease inhibitor and inhibits airway epithelial sodium channel (ENaC) function.Fórmula:C21H26N4O8SPureza:99.31% - 99.85%Forma y color:Crystalline SolidPeso molecular:494.52Ref: TM-T2391
10mg48,00€1mL*10mM (DMSO)50,00€25mg69,00€50mg93,00€100mg116,00€200mg172,00€500mg281,00€CCT 137690
CAS:CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Fórmula:C26H31BrN8OPureza:98.51% - 99.89%Forma y color:SolidPeso molecular:551.48Fadraciclib
CAS:Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM).Fórmula:C21H31N7OPureza:99.75%Forma y color:SolidPeso molecular:397.52Ref: TM-TQ0053
1mg42,00€2mg55,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg145,00€25mg260,00€50mg414,00€100mg583,00€ML216
CAS:ML216 (CID-49852229) inhibits BLM helicase (IC50: 1.8 μM), 28-fold selective over RECQ1, RECQ5, and UvrD (IC50s > 50 μM).Fórmula:C15H9F4N5OSPureza:98.12%Forma y color:SolidPeso molecular:383.32PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Forma y color:SolidPeso molecular:419.48A-286982
CAS:A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.Fórmula:C24H27N3O4SPureza:97.81%Forma y color:SolidPeso molecular:453.55Ref: TM-T21781
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)81,00€10mg107,00€25mg210,00€50mg350,00€100mg522,00€ON-013100
CAS:ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.Fórmula:C19H22O7SPureza:98.27%Forma y color:SolidPeso molecular:394.44Ref: TM-T16391
1mg48,00€1mL*10mM (DMSO)60,00€5mg71,00€10mg100,00€25mg172,00€50mg268,00€100mg404,00€200mg570,00€Tirofiban hydrochloride monohydrate
CAS:Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.Fórmula:C22H39ClN2O6SPureza:98.81% - >99.99%Forma y color:White SolidPeso molecular:495.075-BrdU
CAS:5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!Fórmula:C9H11BrN2O5Pureza:99.54% - 99.87%Forma y color:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:307.1MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Fórmula:C21H19N3O2SPureza:98.80%Forma y color:SolidPeso molecular:377.46Ref: TM-T22106
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg86,00€25mg161,00€50mg245,00€100mg363,00€200mg515,00€LY2334737
CAS:LY2334737 is an orally available prodrug of gemcitabine with antineoplastic activity.Fórmula:C17H25F2N3O5Pureza:98.82%Forma y color:SolidPeso molecular:389.39Ref: TM-T4061
1mg35,00€5mg79,00€1mL*10mM (DMSO)94,00€10mg111,00€25mg215,00€50mg319,00€100mg442,00€200mg583,00€Senexin A
CAS:Senexin A is an effective and selective CDK8 inhibitor that also inhibits CDK19 with Kd values of 0.83 microns and 0.31 microns, respectively.Fórmula:C17H14N4Pureza:99.74%Forma y color:SolidPeso molecular:274.32Ref: TM-T5673
1mg34,00€1mL*10mM (DMSO)71,00€5mg73,00€10mg94,00€25mg177,00€50mg323,00€100mg460,00€200mg622,00€
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