Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(116 productos)
- CDK(548 productos)
- Detención del ciclo celular(5 productos)
- Chk(49 productos)
- DYRK(46 productos)
- Dynamin(27 productos)
- Ferroptosis(233 productos)
- HSP(180 productos)
- Integrin(276 productos)
- Kinesina(87 productos)
- LIM quinasa(21 productos)
- Asociado a microtúbulos(274 productos)
- PKC(128 productos)
- PLK(25 productos)
- ROCK(61 productos)
- Rho(6 productos)
- Wee1(14 productos)
- c-Myc(77 productos)
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Se han encontrado 3937 productos de "Ciclo celular / Checkpoint"
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Z62954982
CAS:Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFórmula:C20H21N3O5SPureza:98.28%Forma y color:SolidPeso molecular:415.46Ref: TM-T37113
1mg35,00€5mg75,00€1mL*10mM (DMSO)87,00€10mg105,00€25mg173,00€50mg255,00€100mg371,00€200mg530,00€Tenidap
CAS:Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.Fórmula:C14H9ClN2O3SPureza:98.56% - 99.42%Forma y color:SolidPeso molecular:320.75N6-(p-Methoxybenzyl)adenosine
CAS:Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormoneFórmula:C18H21N5O5Pureza:99.79%Forma y color:SolidPeso molecular:387.39Ref: TM-TNU0430
1mg141,00€2mg203,00€5mg344,00€10mg505,00€25mg797,00€50mg1.044,00€100mg1.431,00€200mg1.953,00€PDD00017273
CAS:PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.Fórmula:C23H26N6O4S2Pureza:99.14% - 99.21%Forma y color:SolidPeso molecular:514.62Ref: TM-T5700
5mg78,00€1mL*10mM (DMSO)92,00€10mg130,00€25mg269,00€50mg403,00€100mg580,00€500mg1.198,00€O6-Methyldeoxy guanosine
CAS:O6-Methyldeoxy guanosine, a deoxypurine nucleoside, is a weak inhibitor of the removal of O6-methylguanine from methylated DNA by rat liver enzymes in vitro.Fórmula:C11H15N5O4Pureza:99.57%Forma y color:SolidPeso molecular:281.272'-Deoxy-N4-methylcytidine
CAS:2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.Fórmula:C10H15N3O4Pureza:99.61%Forma y color:SolidPeso molecular:241.242'-Deoxy-2-iodoadenosine
CAS:2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.Fórmula:C10H12IN5O3Pureza:99.37%Forma y color:SolidPeso molecular:377.142'-C-β-Methylguanosine
CAS:2'-C-beta-Methylguanosine (2'-C-Methylguanosine), with antiviral activity, inhibits dengue virus 2.Fórmula:C11H15N5O5Pureza:99.37%Forma y color:SolidPeso molecular:297.27DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Fórmula:C20H15NO5Pureza:99.13%Forma y color:SolidPeso molecular:349.34Ref: TM-T37655
1mg73,00€5mg160,00€1mL*10mM (DMSO)170,00€10mg236,00€25mg409,00€50mg595,00€100mg858,00€9-(β-D-Xylofuranosyl)adenine
CAS:9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine hasFórmula:C10H13N5O4Pureza:99.97%Forma y color:SolidPeso molecular:267.24USP1-IN-2
CAS:USP1-IN-2 is a potent USP1 inhibitor with potential anti-tumor activity for the study of cancer.Fórmula:C26H22F4N6OPureza:99.69% - 99.88%Forma y color:SolidPeso molecular:510.486LSN2839567
CAS:LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.Fórmula:C25H28F2N8Pureza:99.14%Forma y color:SolidPeso molecular:478.54RO0270608
CAS:RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Fórmula:C24H19Cl3N2O4Pureza:98.26%Forma y color:SolidPeso molecular:505.78P-2'-deoxyribose
CAS:P-2'-deoxyribose (P-Nucleoside) is a deoxyribose that is widely found in organisms.Fórmula:C11H15N3O5Pureza:99.71%Forma y color:SolidPeso molecular:269.25Ref: TM-TNU1281
1mg109,00€2mg160,00€5mg261,00€10mg374,00€25mg583,00€50mg803,00€100mg1.063,00€200mg1.431,00€5-Bromo-2',3',5'-tri-O-acetyluridine
CAS:5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.Fórmula:C15H17BrN2O9Pureza:99%Forma y color:SolidPeso molecular:449.21Braco-19
CAS:Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in human glioblastoma cells.Fórmula:C35H43N7O2Pureza:97.01%Forma y color:SolidPeso molecular:593.765-Bromouridine
CAS:5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.Fórmula:C9H11BrN2O6Pureza:99.89%Forma y color:White PowderPeso molecular:323.1Bexotegrast
CAS:Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Fórmula:C27H36N6O3Pureza:99.53%Forma y color:SolidPeso molecular:492.612'-O-(2-Methoxyethyl)adenosine
CAS:2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Fórmula:C13H19N5O5Pureza:99.35%Forma y color:SolidPeso molecular:325.32N6-Methyl-2'-O-methyladenosine
CAS:N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound foundFórmula:C12H17N5O4Pureza:99.97%Forma y color:SolidPeso molecular:295.292'-Deoxy-N2-methylguanosine
CAS:2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.Fórmula:C11H15N5O4Pureza:99.79%Forma y color:SolidPeso molecular:281.272'-O-Methyl-2-thiouridine
CAS:2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.Fórmula:C10H14N2O5SPureza:99.89%Forma y color:SolidPeso molecular:274.292',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS:2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication，AIDS and herpes.Fórmula:C21H40N2O6Si2Pureza:99.88%Forma y color:SolidPeso molecular:472.72PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Fórmula:C21H16ClN5O3SPureza:99.19%Forma y color:SolidPeso molecular:453.9Ref: TM-T84770
1mg84,00€5mg170,00€1mL*10mM (DMSO)195,00€10mg281,00€25mg542,00€50mg757,00€100mg1.044,00€Levomefolate sodium
CAS:Levomefolate sodium (L-5-MTHF sodium) is a dietary supplement that can be used to study megaloblastic anemia and neurological disorders.Fórmula:C20H23N7Na2O6Pureza:98.7%Forma y color:SolidPeso molecular:503.42MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Fórmula:C22H21ClFN3O3SPureza:99.22%Forma y color:SolidPeso molecular:461.94Mps1-IN-2
CAS:Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Fórmula:C26H36N6O3Pureza:96.24% - 99.75%Forma y color:SolidPeso molecular:480.6SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Fórmula:C20H27ClN8OSPureza:98.29%Forma y color:SolidPeso molecular:463PF-03814735
CAS:PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Fórmula:C23H25F3N6O2Pureza:98%Forma y color:SolidPeso molecular:474.48Pacanalotamab
CAS:Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.Forma y color:LiquidAcapatamab
CAS:Acapatamab (AMG-160) is a Half-Life Extended (HLE) Bispecific T-cell Engager (BiTE) with domains that bind to PSMA and CD3. It exhibits Kd values of 14.8 nM for hPSMA and 22.4 nM for hCD3. This compound is utilized in cancer research.Forma y color:LiquidN6-Etheno 2'-deoxyadenosine
CAS:N6-Etheno 2'-deoxyadenosine is used as a biomarker to evaluate chronic inflammation and lipid peroxidation in animal or human tissues.Fórmula:C12H13N5O3Pureza:98%Forma y color:SolidPeso molecular:275.26Vibecotamab
CAS:Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.Forma y color:LiquidPOSH-IN-1
CAS:POSH-IN-1 (Compound 108) is an inhibitor of the POSH polypeptide （e3 ligase) and has antiviral, anticancer, and neurodegenerative disease potential.Fórmula:C14H8FNO3SPureza:99.29%Forma y color:SolidPeso molecular:289.28OS-2966
OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.Pureza:95%Forma y color:LiquidPeso molecular:~150 kDaMetribuzin
CAS:Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.
Fórmula:C8H14N4OSPureza:99.07%Forma y color:Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Peso molecular:214.29Alnuctamab
CAS:Alnuctamab (EM901) is a humanized, asymmetric two-arm IgG T-cell engager (TCE) with potential applications in immunological research [1].Forma y color:LiquidRovelizumab
CAS:Rovelizumab, Humanized anti-CD11/CD18 mAb, inhibits overactive leukocytes during shock, for MS, hemorrhagic shock, myocardial infarction, and stroke.Pureza:95% - 95%Forma y color:LiquidRinatabart
CAS:Rinatabart is a humanised monoclonal antibody targeting FRα/FOLR1, suitable for investigating ovarian and endometrial cancers expressing FRα.Pureza:95% - 95.7% (SDS-PAGE); 96.0% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.18 kDaVonsetamig
CAS:Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.Forma y color:LiquidLinvoseltamab
CAS:Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/Forma y color:LiquidPasotuxizumab
CAS:Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.Forma y color:LiquidObrindatamab
CAS:Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.Forma y color:LiquidCaplacizumab
CAS:Caplacizumab (ALX-0681), a humanized anti-von Willebrand factor (vWF) nanobody, serves to impede vWF-mediated platelet adhesion, thereby averting additionalForma y color:LiquidLocked nucleic acid 1
CAS:Locked nucleic acid 1 is an LNA-type nucleoside derivative.Fórmula:C32H32N2O8Pureza:98%Forma y color:SolidPeso molecular:572.61Anti-Mouse TCR γ/δ Antibody (UC7-13D5)
Anti-Mouse TCR gamma/delta Antibody is a host Armenian Hamster-derived IgG class inhibitor targeting the mouse TCR gamma/delta receptor.Forma y color:Odour LiquidEnlimomab
CAS:Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.Forma y color:LiquidVixtimotamab
Vixtimotamab (AMV-564; TandAb T564), a bispecific tetravalent tandem diabody (TandAb), selectively engages human CD33 and CD3 antigens.Forma y color:Odour LiquidFlotetuzumab
CAS:Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.Forma y color:LiquidDHX9-IN-8
CAS:DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].Fórmula:C18H16N2O3S2Forma y color:SolidPeso molecular:372.46
