Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(95 productos)
- CDK(501 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(262 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(69 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
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Se han encontrado 3485 productos de "Ciclo celular / Checkpoint"
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2-Keto-D-galactose
CAS:<p>2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.</p>Fórmula:C6H10O6Pureza:98%Forma y color:SolidPeso molecular:178.14Fozivudine tidoxil
CAS:<p>Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Fórmula:C35H64N5O8PSForma y color:SolidPeso molecular:745.95(Rac)-Managlinat dialanetil
CAS:<p>Managlinat dialanetil, an orally available and potent inhibitor of fructose 1,6-bisphosphatase (FBPase) used in research 2 type diabetes.</p>Fórmula:C21H33N4O6PSPureza:98.52%Forma y color:SolidPeso molecular:500.55DHODH-IN-12
CAS:<p>DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.</p>Fórmula:C10H9N3O2Pureza:99.53%Forma y color:SolidPeso molecular:203.2CAP-53194
CAS:<p>CAP-53194 is a selective Plk1 inhibitor.</p>Fórmula:C21H14N6O5Pureza:98%Forma y color:SolidPeso molecular:430.37CGP 53353
CAS:<p>CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.</p>Fórmula:C20H13F2N3O2Pureza:98.11%Forma y color:SolidPeso molecular:365.33Aditoprime
CAS:<p>Aditoprime inhibits bacterial growth by blocking DHFR, effective against L.casei and E.coli with IC50 of 520/47 nM.</p>Fórmula:C15H21N5O2Forma y color:SolidPeso molecular:303.36GSK-3008348
CAS:<p>GSK-3008348 is an antagonist of integrin alpha(v)beta6.</p>Fórmula:C29H37N5O2Pureza:99.547%Forma y color:SolidPeso molecular:487.64Mivobulin Isethionate
CAS:<p>Mivobulin, a tubulin inhibitor (CI-980), may treat glioma, melanoma, prostate, and ovarian cancer, targeting colchicine-binding site.</p>Fórmula:C19H25N5O6SPureza:98%Forma y color:SolidPeso molecular:451.5PKC-9
CAS:<p>PKC-9 is a PKC-zeta inhibitor 9.</p>Fórmula:C25H25N7Forma y color:SolidPeso molecular:423.51DHODH-IN-20
CAS:<p>Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.</p>Fórmula:C24H25F4N3O3Forma y color:SolidPeso molecular:479.47Picoplatin
CAS:<p>Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.</p>Fórmula:C6H10Cl2N2PtPureza:98%Forma y color:SolidPeso molecular:376.14HHL-6
CAS:<p>HHL-6 is a c-Fos and BDNF protein expression modulator.</p>Fórmula:C19H26N2O3Forma y color:SolidPeso molecular:330.42Metralindole HCl
CAS:<p>Metralindole is a reversible monoamine oxidase A (RIMA) inhibitor, it was investigated as a potential antidepressant.</p>Fórmula:C15H18ClN3OPureza:98%Forma y color:SolidPeso molecular:291.78HR22C16
CAS:<p>HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.</p>Fórmula:C23H23N3O3Forma y color:SolidPeso molecular:389.45JFN05510
CAS:<p>Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.</p>Fórmula:C50H68N7O9PSiForma y color:SolidPeso molecular:970.18HIPP
CAS:<p>HIPP is a highly selective inhibitor of antineoplastic CtBP.</p>Fórmula:C9H9NO3Forma y color:SolidPeso molecular:179.17NPD9948
CAS:<p>NPD9948 is a competitive inhibitor of MTH1.</p>Fórmula:C13H14N6Forma y color:SolidPeso molecular:254.29LDN-209929
CAS:<p>LDN-209929 2HCl is a potent and selective inhibitor of haspin kinase.</p>Fórmula:C17H17ClN2OSForma y color:SolidPeso molecular:332.85DYRKi
CAS:<p>DYRKi is a nontoxic, DYRK1-selective inhibitor.</p>Fórmula:C20H13F3N4O2SForma y color:SolidPeso molecular:430.4BIPM
CAS:<p>BIPM inhibits ROCK2, alters SH-SY5Y cell migration, actin fibers, neurite length, and reduces cofilin phosphorylation.</p>Fórmula:C23H22N2O3Forma y color:SolidPeso molecular:374.43REV7/REV3L-IN-1
CAS:<p>REV7/REV3L-IN-1 is a inhibitor of REV7/REV3L interaction(IC50 of 78 μM),</p>Fórmula:C19H21N3O3SPureza:98%Forma y color:SolidPeso molecular:371.45NSC47924
CAS:<p>NSC47924 is a laminin receptor (LR) inhibitor.</p>Fórmula:C18H17NO2Pureza:98%Forma y color:SolidPeso molecular:279.33AB-182
CAS:<p>AB-182 is an aziridine derivative with antitumor activity.</p>Fórmula:C11H22N3O4PForma y color:SolidPeso molecular:291.28Ro 43-5054
CAS:<p>Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.</p>Fórmula:C24H27N5O7Pureza:98%Forma y color:SolidPeso molecular:497.5ROCK-IN-D1
CAS:<p>ROCK-IN-D1 is an effective and selective inhibitor of ROCK.</p>Fórmula:C22H27N5O2SPureza:98%Forma y color:SolidPeso molecular:425.55SNX2-1-108
CAS:<p>SNX2-1-108 is a selective CDK8 and CDK19 inhibitor.</p>Fórmula:C21H16N4Pureza:98%Forma y color:SolidPeso molecular:324.38L-Guanosine
CAS:<p>L-Guanosine is the L-configuration of Guanosine. Guanosine is a purine nucleoside that has anti-herpesvirus activity [1] [2].</p>Fórmula:C10H13N5O5Forma y color:SolidPeso molecular:283.24LIMK-IN-14
CAS:<p>LIMK-IN-14 is an effective and selective inhibitor of LIMK.</p>Fórmula:C22H27N7O3Pureza:98%Forma y color:SolidPeso molecular:437.49Fosteabine
CAS:<p>Fosteabine is an oral and prodrug analog of cytarabine. It is resistant to deoxycytidine deaminase.</p>Fórmula:C27H50N3O8PPureza:98%Forma y color:SolidPeso molecular:575.67Denopterin
CAS:<p>Denopterin is an antineoplastic agent.</p>Fórmula:C21H23N7O6Pureza:98%Forma y color:SolidPeso molecular:469.45UIAA-II-232
CAS:<p>UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).</p>Fórmula:C20H24FN5O3Forma y color:SolidPeso molecular:401.43Protein kinase D inhibitor 1
CAS:<p>Protein kinase D inhibitor 1 (17m) is a potent pan-PKD suppressant with IC50 of 17-35 nM, targeting cortactin phosphorylation.</p>Fórmula:C19H21N7Forma y color:SolidPeso molecular:347.42BAY-707
CAS:<p>BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.</p>Fórmula:C15H20N4O2Pureza:98%Forma y color:SolidPeso molecular:288.34Cdc7-IN-14
CAS:<p>Cdc7-IN-14 (compound 82) is a potent CDC7 inhibitor with an IC50 < 1 nM, promising for cancer research.</p>Fórmula:C18H20N4O2SForma y color:SolidPeso molecular:356.441-Acetyl-3-o-toluyl-5-fluorouracil
CAS:<p>1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antineoplastic agent.</p>Fórmula:C14H11FN2O4Pureza:98%Forma y color:SolidPeso molecular:290.25Rho-Kinase-IN-2
CAS:<p>Rho-Kinase-IN-2, an oral ROCK inhibitor (IC50=3nM), penetrates the CNS; potential in Huntington's research.</p>Fórmula:C20H25FN4O2Forma y color:SolidPeso molecular:372.44Rabacfosadine succinate
CAS:<p>Rabacfosadine succinate is the acyclic nucleoside phosphonate PMEG double prodrug.</p>Fórmula:C25H41N8O10PPureza:98%Forma y color:SolidPeso molecular:644.623Thiamiprine
CAS:<p>Thiamiprine is an agent with the activity of antineoplastic.</p>Fórmula:C9H8N8O2SForma y color:SolidPeso molecular:292.28Meturedepa
CAS:<p>Meturedepa is an antineoplastic agent.</p>Fórmula:C11H22N3O3PPureza:98%Forma y color:SolidPeso molecular:275.28RK-9123016
CAS:<p>RK-9123016 is a SIRT2 inhibitor.</p>Fórmula:C16H18N6O3SPureza:99.65%Forma y color:SolidPeso molecular:374.42MK-0668
CAS:<p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>Fórmula:C31H30Cl2N6O6SForma y color:SolidPeso molecular:685.58BI-831266
CAS:<p>BI-831266 is a potent and selective Aurora kinase B inhibitor.</p>Fórmula:C27H38ClN7O2Forma y color:SolidPeso molecular:528.09BzDANP
CAS:<p>BzDANP is a modulator of pre-miR-29a maturation by Dicer.</p>Fórmula:C18H24N6Forma y color:SolidPeso molecular:324.42L 703014
CAS:<p>L 703014 is an antagonist of the fibrinogen receptor.</p>Fórmula:C24H34N4O4Pureza:98%Forma y color:SolidPeso molecular:442.55SEC inhibitor KL-2
CAS:<p>KL-2: potent SEC inhibitor, selectively disrupts AFF4-CCNT1, dose-dependent, Ki: 1.50 μM.</p>Fórmula:C17H13ClFNO3Pureza:99.86%Forma y color:SolidPeso molecular:333.74BMH-23
CAS:<p>BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Fórmula:C15H15N3Pureza:98%Forma y color:SolidPeso molecular:237.3(R)-DRF053 dihydrochloride
CAS:<p>cdk/CK1 inhibitor,potent and ATP-competitive</p>Fórmula:C23H29Cl2N7OPureza:98%Forma y color:SolidPeso molecular:490.43AM-TS23
CAS:<p>AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.</p>Fórmula:C17H12N2O3S3Pureza:98%Forma y color:SolidPeso molecular:388.48Scaff10-8
CAS:<p>Scaff10-8 blocks AKAP-Lbc-RhoA, aiding aquaporin-2 movement in kidney cells.</p>Fórmula:C22H18O6Pureza:98%Forma y color:SolidPeso molecular:378.37
