Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
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Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
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GFB-12811
CAS:<p>GFB-12811 is an orally active, selective, and potent CDK5 inhibitor, used in the study of autosomal dominant polycystic kidney disease.</p>Fórmula:C22H23F4N5OPureza:98.88%Forma y color:SolidPeso molecular:449.44HRO761
CAS:<p>HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.</p>Fórmula:C31H31ClF3N9O5Pureza:98.74% - 99.62%Forma y color:SolidPeso molecular:702.08Elacytarabine
CAS:<p>Elacytarabine (M7594 0037), a lipid-conjugated derivative of the nucleoside analog cytarabine, is an antineoplastic drug. It has cytotoxicity in solid tumors.</p>Fórmula:C27H45N3O6Pureza:97.69%Forma y color:SolidPeso molecular:507.66CTPS1-IN-1
CAS:<p>CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.</p>Fórmula:C21H22N6O4S2Pureza:99.46%Forma y color:SolidPeso molecular:486.57LY3143921 hydrate
CAS:<p>LY3143921 ((S)-Example 2) hydrate is an orally active CDC7 kinase inhibitor with broad in vitro anticancer activity [1].</p>Fórmula:C16H14FN5O2Pureza:98.43%Forma y color:SolidPeso molecular:327.31SR 11302
CAS:<p>SR 11302 is an inhibitor of activator protein-1 (AP-1).</p>Fórmula:C26H32O2Pureza:98.65%Forma y color:SolidPeso molecular:376.53INCB086550
CAS:<p>INCB086550 (PD-1/PD-L1-IN-8) (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.</p>Fórmula:C41H39N7O4Pureza:98.49%Forma y color:SolidPeso molecular:693.79Troxacitabine
CAS:<p>Troxacitabine, a DNA polymerase inhibitor, is potentially used for the treatment of acute myeloid leukemia (AML). In comparison with gemcitabine, troxacitabine was equally active against MiaPaCa and was more efficacious against Panc-01.</p>Fórmula:C8H11N3O4Pureza:98%Forma y color:SolidPeso molecular:213.19Bicyclomycin benzoate
CAS:<p>Bicyclomycin benzoate (BCM benzoate, FR2054) is a broad-spectrum antibiotic and selective Rho protein inhibitor active against Gram-negative bacteria.</p>Fórmula:C19H22N2O8Forma y color:SolidPeso molecular:406.39Tanuxiciclib
CAS:<p>Tanuxiciclib is a cyclin dependent kinase (CDK) inhibitor, specifically designed to interfere with cell cycle progression by inhibiting the activity of CDKs, which are crucial regulators of cell division.</p>Fórmula:C15H13FN6OForma y color:SolidPeso molecular:312.308Ethynylcytidine
CAS:<p>Ethynylcytidine is a nucleoside antimetabolite.</p>Fórmula:C11H13N3O5Pureza:98%Forma y color:SolidPeso molecular:267.245'-DMT-3'-TBDMS-ibu-rG
CAS:<p>5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.</p>Fórmula:C41H51N5O8SiForma y color:SolidPeso molecular:769.96Formycin A
CAS:<p>Formycin A shows antitumor and antiviral activities. Formycin A , a purine nucleoside antibiotic, is a potent human immunodeficiency virus type 1 (HIV-1) inhibitor with an EC50 of 10 μM.</p>Fórmula:C10H13N5O4Pureza:98%Forma y color:SolidPeso molecular:267.24NSC639828
CAS:<p>NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.</p>Fórmula:C18H13BrClN5O3Forma y color:SolidPeso molecular:462.695'-O-DMT-N6-ibu-dA
CAS:<p>5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.</p>Fórmula:C35H37N5O6Forma y color:SolidPeso molecular:623.715'-O-TBDMS-dT
CAS:<p>5’-O-TBDMS-dT is a nucleoside with protective and modification effects.</p>Fórmula:C16H28N2O5SiForma y color:SolidPeso molecular:356.49PLK1-IN-6
<p>PLK1-IN-6: potent, selective PLK1 inhibitor, IC50 = 0.45 nM, hinders cancer cell growth.</p>Fórmula:C28H37N9O3Forma y color:SolidPeso molecular:547.65GSK-3/CDK5/CDK2-IN-1
CAS:<p>GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].</p>Fórmula:C21H22N4O2Forma y color:SolidPeso molecular:362.4332'-Deoxy-2'-fluoro-5-iodouridine
CAS:<p>2'-Deoxy-2'-fluoro-5-iodouridine is a nucleoside, specifically a fluoro-modified and halo-nucleoside.</p>Fórmula:C9H10FIN2O5Forma y color:SolidPeso molecular:372.09N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine
CAS:<p>N6-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyadenosine, catalog number T66118 and CAS number 64325-78-6, is a valuable organic compound for life sciences research.</p>Fórmula:C38H35N5O6Forma y color:SolidPeso molecular:657.727Deoxypseudouridine
CAS:<p>Deoxypseudouridine is a nucleotide analog.</p>Fórmula:C9H12N2O5Forma y color:SolidPeso molecular:228.2Ref: TM-T13645
Producto descatalogado6-Amino-5-nitropyridin-2-one
CAS:<p>6-Amino-5-nitropyridin-2-one, a pyridine derivative, serves as a nucleobase within hachimoji DNA, where it is specifically paired with 5-aza-7-deazaguanine.</p>Fórmula:C5H5N3O3Pureza:98%Forma y color:SolidPeso molecular:155.11Ribocil-C
CAS:<p>Ribocil-C is a selective inhibitor of the bacterial riboflavin riboswitch, a synthetic analogue of flavin mononucleotide (FMN), inhibits bacterial cell growth.</p>Fórmula:C21H21N7OSPureza:98%Forma y color:SolidPeso molecular:419.5MitoE10
CAS:<p>MitoE10 is an effective mitochondrial targeting antioxidant.</p>Fórmula:C42H55O5PSForma y color:SolidPeso molecular:702.92Tibremciclib
CAS:<p>Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].</p>Fórmula:C28H32F2N8Pureza:98%Forma y color:SolidPeso molecular:518.6PHI-101
CAS:<p>PHI-101 is a checkpoint kinase 2 (Chk2) inhibitor that can be used for the study of refractory acute myeloid leukemia (AML) and ovarian cancer.</p>Fórmula:C19H19FN4O2SPureza:99.4%Forma y color:SolidPeso molecular:386.44YK-2168
CAS:<p>YK-2168 is a differentiated selective inhibitor of CDK9.</p>Fórmula:C16H18ClN5Forma y color:SolidPeso molecular:315.80Ref: TM-T200769
Producto descatalogado
