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Ciclo celular / Checkpoint

Ciclo celular / Checkpoint

Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.

Subcategorías de "Ciclo celular / Checkpoint"

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Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"

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  • Haspin-IN-2
    Targetmol
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    Haspin-IN-2

    CAS:
    <p>Haspin-IN-2 is a potent haspin inhibitor (IC50: 50 nM) and also inhibits CLK1 (IC50: 445 nM) and DYRK1A (IC50: 917 nM).</p>
    Fórmula:C12H8N4O3
    Forma y color:Solid
    Peso molecular:256.22

    Ref: TM-T60394

  • Fradafiban
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    Fradafiban

    CAS:
    <p>Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.</p>
    Fórmula:C20H21N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:367.40

    Ref: TM-T11322

  • Logo de CymitQuimica
    Targetmol
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    2'-F-UMP

    CAS:
    <p>2'-F-UMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Fórmula:C9H12FN2O8P
    Peso molecular:326.17

    Ref: TM-TSW-00948

  • 6-B345TTQ
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    6-B345TTQ

    CAS:
    <p>6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.</p>
    Fórmula:C22H20BrNO4
    Forma y color:Solid
    Peso molecular:442.303

    Ref: TM-T204244

  • Galidesivir
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    Galidesivir

    CAS:
    <p>Galidesivir (BCX4430) is an antiviral compound that inhibits viral RNA-dependent RNA polymerase (RdRp) activity and reduces lung infections in infected animals.</p>
    Fórmula:C11H15N5O3
    Pureza:96.73% - 99.13%
    Forma y color:Solid
    Peso molecular:265.27

    Ref: TM-T10491

  • Des-ethyl-carafiban
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    Des-ethyl-carafiban

    CAS:
    <p>Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.</p>
    Fórmula:C22H23N5O5
    Forma y color:Solid
    Peso molecular:437.448

    Ref: TM-T206156

  • 2′-O-MOE-AMP
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    2′-O-MOE-AMP

    CAS:
    <p>2′-O-MOE-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Fórmula:C13H20N5O8P
    Forma y color:Solid
    Peso molecular:405.30

    Ref: TM-TSW-00946

  • CDK4/6-IN-13
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    CDK4/6-IN-13

    CAS:
    <p>Compounds 10B and 10C: potent cdk4/6 inhibitors with low nM activity, great antiproliferative effects, excellent metabolism, and good pharmacokinetics.</p>
    Fórmula:C25H29N7O
    Forma y color:Solid
    Peso molecular:443.54

    Ref: TM-T62605

  • Aurora B inhibitor 1
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    Aurora B inhibitor 1

    CAS:
    <p>Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor (Ki &lt;0.010 uM) with potential anticancer activity for cancer research.</p>
    Fórmula:C25H26ClF2N7O2
    Pureza:98.37%
    Forma y color:Solid
    Peso molecular:529.97

    Ref: TM-T12010

  • PD-1/PD-L1-IN-53
    Targetmol
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    PD-1/PD-L1-IN-53

    CAS:
    <p>PD-1/PD-L1-IN-53 (compound B3) serves as an inhibitor targeting both the PD-1/PD-L1 and VISTA signaling pathways. It is utilized in cancer research.</p>
    Fórmula:C31H37N3O4
    Forma y color:Solid
    Peso molecular:515.64

    Ref: TM-T200774

  • Logo de CymitQuimica
    Targetmol
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    2'-F-AMP

    CAS:
    <p>2'-F-AMP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Fórmula:C10H13FN5O6P
    Peso molecular:349.21

    Ref: TM-TSW-00945

  • CDK2-IN-30
    Targetmol
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    CDK2-IN-30

    CAS:
    <p>CDK2-IN-30 (Formula (I)) is a CDK2 inhibitor with an IC50 of ≤20 nM, utilized primarily in tumor research.</p>
    Fórmula:C18H25N7O3S
    Forma y color:Solid
    Peso molecular:419.50

    Ref: TM-T200706

  • LNA-UTP
    Targetmol
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    LNA-UTP

    CAS:
    <p>LNA-UTP is a nucleotide analogue used in the synthesis of oligonucleotides.</p>
    Fórmula:C10H15N2O15P3
    Forma y color:Solid
    Peso molecular:496.15

    Ref: TM-TSW-00943

  • BWC0977
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    BWC0977

    CAS:
    <p>BWC0977 is an effective topoisomerase inhibitor that disrupts bacterial DNA replication by targeting both DNA gyrase and topoisomerase IV. The minimum inhibitory concentration (MIC90) of BWC0977 against MDR (multi-drug resistant) Gram-negative bacteria ranges from 0.03 to 2 µg/mL.</p>
    Fórmula:C22H21FN6O5
    Forma y color:Solid
    Peso molecular:468.44

    Ref: TM-T201074

  • DYRK1-IN-1
    Targetmol
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    DYRK1-IN-1

    CAS:
    <p>DYRK1-IN-1: Selective DYRK1A inhibitor with IC50 of 220 nM, good permeability, CNS penetrant for research, no P-glycoprotein issues.</p>
    Fórmula:C12H12N6
    Forma y color:Solid
    Peso molecular:240.26

    Ref: TM-T60334

  • GSK3-IN-10
    Targetmol
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    GSK3-IN-10

    CAS:
    <p>GSK3-IN-10 (Compound 4) is a multi-target inhibitor primarily affecting GSK3α and GSK3β with IC50 values of 1.0 nM and 2.0 nM, respectively. It inhibits the activation of β-catenin, enhances neuronal survival, and provides protective effects against endoplasmic reticulum stress.</p>
    Fórmula:C17H18F2N4O3
    Forma y color:Solid
    Peso molecular:364.347

    Ref: TM-T206481

  • Logo de CymitQuimica
    Targetmol
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    Antitumor agent-74

    <p>Antitumor agent-74, a quinazoline derivative, inhibits DNA, arrests cell cycle, and induces apoptosis with agent-75.</p>
    Fórmula:C26H23FN6
    Forma y color:Solid
    Peso molecular:438.5

    Ref: TM-T62509

  • Pseudouridine 5'-OTBDPS
    Targetmol
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    Pseudouridine 5'-OTBDPS

    CAS:
    <p>Pseudouridine5'-OTBDPS [5-(5-O-TBDPS-β-D-ribofuranosyl)uracil] is an intermediate of Pseudouridine.</p>
    Fórmula:C25H30N2O6Si
    Forma y color:Solid
    Peso molecular:482.60

    Ref: TM-TSW-00962

  • N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine
    Targetmol
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    N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine

    CAS:
    <p>N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a nucleoside analog that resembles the natural nucleotide adenosine in structure. It acts as an activator of ribonucleotide reductase, facilitating the conversion of ribonucleotides into deoxyribonucleotides.</p>
    Fórmula:C38H35N5O6
    Forma y color:Solid
    Peso molecular:657.714

    Ref: TM-T206424

  • RNAP-σ interaction inhibitor-1
    Targetmol
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    RNAP-σ interaction inhibitor-1

    CAS:
    <p>RNAP-σ interaction inhibitor-1 (compound 5d) acts as an inhibitor of the interaction between RNA polymerase and the sigma factor. It exhibits activity against Streptococci with a minimum inhibitory concentration (MIC) ranging from 1-2 µg/mL.</p>
    Fórmula:C19H11Cl3N2O6S2
    Forma y color:Solid
    Peso molecular:533.79

    Ref: TM-T207529