Ciclo celular / Checkpoint
Los inhibidores del ciclo celular/puntos de control son compuestos que interrumpen la progresión normal del ciclo celular, particularmente en puntos de control regulatorios clave. Estos inhibidores son cruciales para estudiar la división celular, comprender la proliferación de células cancerosas y desarrollar terapias anticancerígenas. Al dirigirse a fases específicas del ciclo celular, estos inhibidores pueden inducir la detención del ciclo celular, lo que lleva a apoptosis o senescencia en células de división rápida. En CymitQuimica, ofrecemos una amplia gama de inhibidores de alta calidad del ciclo celular/puntos de control para apoyar su investigación en biología del cáncer, biología celular y desarrollo de fármacos.
Subcategorías de "Ciclo celular / Checkpoint"
- Aurora quinasa(94 productos)
- CDK(500 productos)
- Detención del ciclo celular(4 productos)
- Chk(42 productos)
- DYRK(48 productos)
- Dynamin(23 productos)
- Ferroptosis(215 productos)
- HSP(169 productos)
- Integrin(224 productos)
- Kinesina(66 productos)
- LIM quinasa(19 productos)
- Asociado a microtúbulos(261 productos)
- PKC(102 productos)
- PLK(28 productos)
- ROCK(70 productos)
- Rho(2 productos)
- Wee1(15 productos)
- c-Myc(69 productos)
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Se han encontrado 3477 productos de "Ciclo celular / Checkpoint"
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MYCi975
CAS:<p>MYCi975 (NUCC-0200975) is an orally active inhibitor of MYC.</p>Fórmula:C25H16Cl2F6N2O2Pureza:99.3% - 99.82%Forma y color:SolidPeso molecular:561.3Vitamin D2
CAS:<p>Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.</p>Fórmula:C28H44OPureza:98.73% - 99.89%Forma y color:Prisms From Acetone 1998)Peso molecular:396.65R-10015
CAS:<p>R-10015, potent LIMK inhibitor with 38 nM IC50 for LIMK1, targets ATP pocket, and serves as a broad-spectrum HIV antiviral.</p>Fórmula:C20H19ClN6O2Pureza:98.68%Forma y color:SolidPeso molecular:410.86Abciximab
CAS:<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Pureza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Forma y color:LiquidPeso molecular:95.18 kDaEfalizumab
CAS:<p>Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.</p>Pureza:SDS-PAGE:95% SEC-HPLC:98.77%Forma y color:LiquidPeso molecular:146.14 kDaCirtuvivint
CAS:<p>Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.</p>Fórmula:C24H25N7OPureza:99.46% - >99.99%Forma y color:SolidPeso molecular:427.5Centrinone
CAS:<p>Centrinone (LCR-263) (LCR-263) is a reversible inhibitor of polo-like kinase 4 (PLK4; Ki:0.16 nM).</p>Fórmula:C26H25F2N7O6S2Pureza:98.76%Forma y color:SolidPeso molecular:633.65Paprotrain
CAS:<p>Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.</p>Fórmula:C16H11N3Pureza:99.91%Forma y color:SolidPeso molecular:245.28XPW1
CAS:<p>XPW1 is a CDK9 inhibitor with antitumor activity, inhibits DNA repair procedures, and can be used for the research of clear cell renal cell carcinoma.</p>Fórmula:C36H39ClFN7O2Pureza:98.08%Forma y color:SoildPeso molecular:656.19DI-87
CAS:<p>DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.</p>Fórmula:C23H30N6O3S2Pureza:99.76%Forma y color:SolidPeso molecular:502.656-Mercaptopurine
CAS:<p>6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.</p>Fórmula:C5H4N4SPureza:99.53% - 99.63%Forma y color:Yellow Crystalline Powder SolidPeso molecular:152.18Metarrestin
CAS:<p>Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.</p>Fórmula:C31H30N4OPureza:99.45%Forma y color:SolidPeso molecular:474.6N-Dodecyl-β-D-maltoside
CAS:<p>N-Dodecyl-β-D-maltoside (Lauryl Maltoside) has also been employed in applications such as in the purification and stabilization of RNA polymerase and the</p>Fórmula:C24H46O11Pureza:99.7% - >99.99%Forma y color:White PowderPeso molecular:510.62MALAT1-IN-1
CAS:<p>MALAT1-IN-1 is an effective dose-dependent Malat1 inhibitor, not altering Neat1 expression.</p>Fórmula:C19H21N3O2Pureza:99.58%Forma y color:SolidPeso molecular:323.39CDK2-IN-4
CAS:<p>CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.</p>Fórmula:C23H18N6O2SPureza:97.24% - 99.10%Forma y color:SolidPeso molecular:442.49Ribavirin
CAS:<p>Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.</p>Fórmula:C8H12N4O5Pureza:99.09% - 99.83%Forma y color:Less Solid Colourless SolidPeso molecular:244.20Famciclovir
CAS:<p>Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.</p>Fórmula:C14H19N5O4Pureza:99.85%Forma y color:Off-White PowderPeso molecular:321.33N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine
<p>N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.</p>Fórmula:C41H43N3O9Forma y color:SolidPeso molecular:721.79Clofarabine-5'-triphosphate
CAS:<p>Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.</p>Fórmula:C10H14ClFN5O12P3Forma y color:SolidPeso molecular:543.62Erythromycin thiocyanate
CAS:<p>Erythromycin thiocyanate, a macrolide from Streptomyces erythreus, binds 50S ribosomes, halting protein synthesis in bacteria.</p>Fórmula:C38H68N2O13SPureza:98%Forma y color:SolidPeso molecular:793.02
