GPCR / proteína G
Los inhibidores de GPCR/proteínas G son compuestos que se dirigen a los receptores acoplados a proteínas G (GPCR) y a las proteínas G asociadas, que desempeñan roles cruciales en la transmisión de señales desde el exterior hacia el interior de las células. Estos inhibidores son esenciales para estudiar las vías de señalización mediadas por los GPCR, que están involucradas en numerosos procesos fisiológicos, incluyendo la percepción sensorial, la respuesta inmunitaria y la neurotransmisión. Los inhibidores de GPCR también son importantes en el desarrollo de fármacos, ya que muchos agentes terapéuticos tienen como objetivo estos receptores. En CymitQuimica, ofrecemos una amplia gama de inhibidores de GPCR/proteínas G de alta calidad para apoyar su investigación en farmacología, biología celular y campos relacionados.
Subcategorías de "GPCR / proteína G"
- Receptor 5-HT(1.025 productos)
- Receptor de adenosina(251 productos)
- Receptor adrenérgico(3.028 productos)
- Receptor de bombesina(35 productos)
- Receptor de bradicinina(61 productos)
- CXCR(158 productos)
- CaSR(34 productos)
- Receptor de cannabinoides(218 productos)
- Colecistoquinina(1 productos)
- Receptor de dopamina(445 productos)
- Receptor de endotelina(86 productos)
- Receptor GNRH(84 productos)
- GPCR19(36 productos)
- GRK(33 productos)
- GTPasa(23 productos)
- Receptor de glucagón(195 productos)
- Hedgehog / Smoothened(49 productos)
- Receptor de histamina(385 productos)
- Receptor LPA(21 productos)
- Receptor de melatonina(26 productos)
- Receptor de OX(41 productos)
- Receptor de opioides(327 productos)
- PAFR(14 productos)
- PKA(61 productos)
- Receptor S1P(18 productos)
- SGLT(31 productos)
- Receptor sigma(46 productos)
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Se han encontrado 6011 productos de "GPCR / proteína G"
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(E/Z)-Ozagrel sodium
CAS:(E/Z)-Ozagrel (sodium) [(E/Z)-OKY-046 (sodium)] is a mixture of the EZ isomers of Ozagrel (sodium). It acts as a thromboxane A2 (TXA2) synthase inhibitor. As an antiplatelet agent, Ozagrel (sodium) selectively inhibits human platelet aggregation, with an IC50 of 53.12 μM.Fórmula:C13H11N2NaO2Forma y color:SolidPeso molecular:250.228PD 135158
CAS:PD 135158 is a CCK2 receptor antagonist.Fórmula:C42H61N5O11Pureza:98%Forma y color:SolidPeso molecular:811.96CP-865569
CAS:CP-865569 is a CCR1 antagonist useful in the research of inflammatory and autoimmune diseases, including conditions such as rheumatoid arthritis and multiple sclerosis.Fórmula:C22H26ClFN2O5SForma y color:SolidPeso molecular:484.9695-HT6/5-HT2AR antagonist-1
Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM & 39 nM.Fórmula:C21H26N6SForma y color:SolidPeso molecular:394.54PGDM
CAS:PGD2 is involved in allergy, asthma, sleep, temperature regulation, inhibits clotting, and relaxes blood vessels; PGDM, its metabolite, is a biomarker.Fórmula:C16H24O7Forma y color:SolidPeso molecular:328.36Sulprostone
CAS:EP3 and EP1 receptor agonistFórmula:C23H31NO7SPureza:98%Forma y color:White To Off-White SolidPeso molecular:465.56Dopamine D3 receptor ligand-1
Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:Fórmula:C27H29N5OForma y color:SolidPeso molecular:439.55MRS7799
CAS:MRS7799 is a selective A3 Adenosine Receptor antagonist with Kd values of 0.55 nM for humans, 3.74 nM for mice, and 2.80 nM for rats. MRS7799 can be utilized in research related to neurodegenerative diseases, cancer, cardiac and cerebral ischemia, and autoimmune inflammatory diseases.Fórmula:C22H18N4OSForma y color:SolidPeso molecular:386.47(S)-Butaprost free acid
CAS:(S)-Butaprost (free acid) is a potent and highly selective EP2 receptor agonist[1].Fórmula:C23H38O5Forma y color:SolidPeso molecular:394.54KAG-308
CAS:KAG-308: selective EP4 agonist; Ki: 2.57 nM, EC50: 17 nM; suppresses colitis, promotes mucosal healing, inhibits TNF-α.Fórmula:C24H30F2N4O3Pureza:98%Forma y color:SolidPeso molecular:460.52Alixorexton
CAS:Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.Fórmula:C21H30N2O5SForma y color:SolidPeso molecular:422.538MRGPRX1 agonist 3
Compound 1f, a potent MRGPRX1 agonist, has an EC50 of 0.22 μM, useful for neuropathic pain studies.Fórmula:C14H11FN2OSForma y color:SolidPeso molecular:274.31H3R antagonist 5
CAS:H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.Fórmula:C23H32N2O4Forma y color:SolidPeso molecular:400.511Thielavin B
CAS:Thielavin B, from Thielavia terricola, inhibits prostaglandin E2 synthesis and reduces rat oedema.Fórmula:C31H34O10Forma y color:SolidPeso molecular:566.6BW A868C
CAS:BW A868C is a potent, selective PGD2 antagonist and a BW245C analogue, inert to other prostaglandin receptors.Fórmula:C25H37N3O5Forma y color:SolidPeso molecular:459.58CRHR1 antagonist 1
CAS:CRHR1 antagonist 1 (compound 10a) is a non-peptide antagonist of corticotropin-releasing hormone receptor 1 (CRHR1). It serves as a useful tool in the study of psychiatric disorders.Fórmula:C24H34N4OForma y color:SolidPeso molecular:394.553MDA7
CAS:MDA7 is a selective agonist of the cannabinoid receptor 2 (CB2), demonstrating an EC50 of 128 nM in human CB2 receptors and 67.4 nM in rat CB2 receptors. The compound exhibits good affinity for CB2 receptors, with Ki values of 422 nM for humans and 238 nM for rats. In rat models, MDA7 shows analgesic activity.Fórmula:C22H25NO2Forma y color:SolidPeso molecular:335.439Inupadenant HCl
CAS:Inupadenant (EOS-850) is a selective A2a receptor antagonist, targeting immunosuppression in tumors.Fórmula:C25H27ClF2N8O4S2Forma y color:SolidPeso molecular:641.11Anthrotainin
CAS:Anthrotainin is a tetracyclic compound that acts as an inhibitor of the binding of P substance (substance P), with an IC50 of 3 μM.Fórmula:C20H17NO9Forma y color:SolidPeso molecular:415.35YNT-3708
CAS:YNT-3708 is an orexin receptor (OXR) agonist, exhibiting EC50 values of 14.6 nM for OX1R and 277 nM for OX2R.Fórmula:C35H36N4O6SForma y color:SolidPeso molecular:640.749
