Étalons de l'industrie alimentaire

<p>Applications P-Phenyl-P-(2,4,6-trimethylbenzoyl)-Phosphinic acid Ethyl Ester is a photoinitiator for UV curable coatings.<br>References Bauer, F., et al.: Prog. Org. Coat., 60, 121 (2007); Rouby, M., et al.: Eur. Polym. J., 31, 301 (1995); Iojoiu, C., et al.: Eur. Polym. J., 36, 2115 (2000)<br></p>

<p>Applications N-(2-Aminoethyl)-1-naphthylacetamide is a metabolite of Naphazoline that has been seen to be a strong collector for pyrophyllite.<br>References Yesilada, A., et. al.: J. Liq. Chromatogr. R.T., 21, 2575 (1998); Zhao, S.M., et. al.: Miner. Eng., 16, 1031 (2003)<br></p>

<p>Applications A metabolite of Voriconazole (V760000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sanati, H., et al.: Antimicrob. Ag. Chemother., 41, 2492 (1997), Geist, M., et al.: Antimicrob. Agents. Chemother., 50, 3227 (2006), Yamazaki, H., et al.: Drug. Metab. Dispos., 34, 1803 (2006), Yamazaki, H., et al.: Xenobiotica, 36, 1201 (2006),<br></p>

<p>Stability Hygroscopic<br>Applications Alitame Hydrate is a dipeptide amide derivative of aspartic acid used as an artificial sweetener. Alitame is about ten times sweeter than Aspartame (A790015) with a half life about twice as long.<br>References Glowaky, R.C. et al.: ACS. Symp. Ser., 450, 57 (1991); Hendrick, M.E. et al.: Adv. Sweet., 226 (1996); Auerbach, M.H. et al.: Food Sci. Technol., 112, 31 (2001);<br></p>

<p>Stability Light Sensitive<br>Applications N-Nitroso-di-n-butylamine (cas# 924-16-3) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications Thrombolytic.<br>References Shen, Z-Q., et al.: Planta Med., 69, 1109 (2003),<br></p>

<p>Applications Irgacure 127 is a difunctional radical photoinitiator. It has been used as an initiator in the preparation and characterization of molecularly imprinted polymers based on thiourea receptors for nitro compound recognition.<br>References Dietlin C., et al., J. Appl. Polym. Sci., 107, 246-252 (2008); Athikomrattanakul U., et al, Talanta, 84, 274-279 (2011)<br></p>

<p>Stability Light Sensitive<br>Applications (+)-Limonene is used in the synthesis of Lavandulol (L195300), a compound in the cosmetics industry. In addition its used in the epoxidation of olefins. This compound is a contaminant of emerging concern (CECs).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gliszczynska, A. et al.: Tetrahedron Lett., 52, 4461 (2011); Majetich, G. et al.: Tetrahedron Lett., 51, 6830 (2010);<br></p>

<p>Applications A labelled metabolite of Dichloropropanols.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Velisek, J., et al.: J. Agric. Food Chem., 28, 1142 (1980), Johnson, J., et al.: Anal. Chem., 62, 2162 (1990),<br></p>

<p>Applications rac 1,2-Bis-palmitoyl-3-chloropropanediol-D5 was useful for establishing an analytical method for quantifying free and ester bound 2-​, 3-​MCPD, and esterified glycidol in fishery products.<br>References Karl, H., et al.: Eur. J. Lipid Sci. Technol., 118, 406 (2016)<br></p>

<p>Applications 2-Ethyl-anthraquinone can be used as a photoinitiator of crosslinking or degradation of polyethylene.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zamotaev, P., et al.: Plasticheskie Massy, 9, 31 (1986); Litsov, N., et al.: Polym. Degrad. Stabil., 32, 1 (1991); Hwang, J., et al.: Stud. Surf. Sci. Catal., 135, 4469 (2001)<br></p>

<p>Applications Labelled Glycidyl Oleate. Used for preparation of Lysophosphatidic acid analogs as agonists of the edg2 lysophosphatidic acid receptor.<br>References Lee, M., et al.: J. Biol. Chem., 271, 11272 (1996), Macrae, A., et al.: Mol. Brain Res., 42, 245 (1996), Hopper, D., et al.: J. Med. Chem., 42, 963 (1999),<br></p>

<p>Impurity Leflunomide USP Related Compound B<br>Applications rac A77 1726 is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. The second Phase III study evaluating the efficacy of Genzyme’s teriflunomide therapy against relapsing forms of multiple sclerosis found the once-daily oral drug to be no less effective than injectable interferon beta 1a (Rebif®). Leflunomide USP Related Compound B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kirsch, B.M., et al.: Arthritis Research and Therapy, 7, 3, R694, (2005)<br></p>

<p>Applications Butyl Acrylate is one of the monomers used in the synthesis of a polyacrylate emulsion thickening agent synthesized by emulsion polymerization. Butyl Acrylate is also used as a reagent in the synthesis of new bis(acyl)phosphane oxide photoinitiators for surface functionalization of cellulose nanocrystals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dang, Ch., et al.: Shanghai Tuliao, 53, 6 (2015); Yu, J., et al.: Carbohyd. Polym., 141, 143 (2016)<br></p>

<p>Stability Light Sensitive<br>Applications Potential inhibitor of Monoacylglycerol Lipase.<br>References Cisneros, J., et al.: J. Med. Chem., 50, 5012 (2007),<br></p>

<p>Applications A metabolite of catecholamines.<br>References Canfell, P., et al.: Clin. Chem., 32, 222 (1986), Nunez, C., et al.: Eur. J .Clin. Chem. Clin. Biochem., 32, 461 (1994), Weise, M., et al.: J. Clin. Endocrinol. Metab., 87, 1955 (2002),<br></p>

<p>Applications Labelled Glycidol. Stabilizer in manufacturing of vinyl polymers; intermediate in synthesis of glycerol, glycidyl ethers, and amines; additive for oil and synthetic hydraulic fluids; epoxy resin diluent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hiles, R.A., et al.: Food Cosmet. Toxicol., 19, 347 (1981), Thompson, E.D., et al.: Food Chem. Toxicol., 22, 665 (1984),<br></p>

<p>Applications Used for preparation of Lysophosphatidic acid analogs as agonists of the edg2 lysophosphatidic acid receptor.<br>References Lee, M., et al.: J. Biol. Chem., 271, 11272 (1996), Macrae, A., et al.: Mol. Brain Res., 42, 245 (1996), Hopper, D., et al.: J. Med. Chem., 42, 963 (1999),<br></p>

<p>Applications 4,4'-Bis(dimethylamino)benzophenone (cas# 90-94-8) is a useful research chemical.<br></p>

<p>Applications Glycidyl Stearate is an acid-hydrolyzable ester derivatives as low calorie fat mimetics. It is used in frying oil, margarine, ice cream, milk substitutes and bakery. Carcinogenic substance.<br>References Swern, D., et al.: Cancer Res., 30, 1037 (1970), Miyamoto, M., et al.: Macromolecules, 30, 6067 (1997),<br></p>

<p>Applications A labelled metabolite of Ketamine (K165300).<br>References Sullivan, H., et al.: J. Med. Chem., 16, 909 (1973), Moreton, J., et al.: J. Pharmacol. Exp. Ther., 203, 303 (1977), Lin, H., et al.: J. Food Drug Anal., 13, 107 (2005),<br></p>

<p>Stability Hygroscopic, Temperature Sensitive<br>Applications A metabolite of Ceftiofur (C244700), which is microbiologic active.<br>References Washburn, K., et al.: J. Vet. Pharm. Ther., 28, 247 (2005),<br></p>

<p>Applications 1-(3,5-di-tert-butyl-4-hydroxyphenyl)ethanone (cas# 14035-33-7) is a useful research chemical.<br></p>

<p>Applications 2,2'-Bis(2-chlorophenyl)-4,4',5,5'-tetraphenyl-1,2'-biimidazole (CAS# 7189-82-4) is a hexaarylbiimidazole (HABI), a visible light thiol-ene photoinitiator, such as in the polymerization of 1,6-hexanediol diacrylate by hexaarylbisimidazoles and heterocyclic mercapto compounds.<br>References Ahn, D.; et al.: Dent. Mater., 31, 1075 (2015); Berdzinski, S.; et al.: Photochemical and Photobiological Sciences, 13, 789 (2014).<br></p>

<p>Applications Labelled 1,3-Distearoyl-2-chloropropanediol (D493510). New lipids in food protein hydrolyzates.<br>References Velisek, J., et al.: J. Agric. Chem., 28, 1142 (1980),<br></p>

<p>Applications 3-Hydroxyanthranilic Acid is one of the tryptophan’s metabolites along the kynurenine pathway. 3-Hydroxyanthranilic Acid has been shown to induce apoptosis in T cells.<br>References Hiramatsu, R. et al.: J. Cell. Biochem., 103, 42 (2007); Bauer, T. et al.: Transpl. Int., 18, 95 (2005)<br></p>

<p>Applications Labelled Estradiol. Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke.<br>References Salole, E.G., Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstret. Gynecol., 156, 1289 (1987), Kuhnz, W., et al.: Arzneim.-Forsch., 43, 966 (1993),<br></p>

<p>Applications Labelled Benzyl Butyl Phthalate (B233555). A phthalate metabolite with genotoxic effect.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reyes, F., et al.: J. Clin. Endocrinol. Metab., 37, 74 (1973), Engel, S., et al.: Neurotoxicology, 30, 522 (2009),<br></p>

<p>Applications An antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.Environmental contaminants; Food contaminants<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),<br></p>

<p>Applications 2,2-Bis(4-hydroxyphenyl)-1,1,1-trichloroethane is an active metabolite of Methoxychlor that acts via the estrogen receptor (ER) to stimulate estrogen response element (ERE)-mediated gene transcription in estrogen-sensitive tissues. 2,2-Bis(4-hydroxyphenyl)-1,1,1-trichloroethane is used in epoxy resins and other epoxide compositions as industrial materials and electric insulators.<br>References Willard, S. et al.: Res. J. Med. Med. Sci., 4, 171 (2009); Brzozowski, Z.K. et al.: Polimery, 17, 419 (1972); Kielkiewicz, J. et al.: Konf. Kunstst. Masch.-Fahrzeugbau. Vortr., 3, 325 (1973);<br></p>

<p>Applications An inhibitor of monoacylglycerol lipase and fatty acid amide hydrolase.<br>References Karlsson, M., et al.: J. Biol. Chem., 272, 27218 (1997), de Lago, E., et al.: Biochem. Pharmacol., 70, 446 (2005), Romero, F., et al.: J. Med. Chem., 50, 1058 (2007),<br></p>

<p>Impurity Esomeprazole EP Impurity E/ Omeprazole Impurity E<br>Applications A metabolite of Omeprazole.<br>References Miner, P., et al.: Am. J. Gastroenterology, 98, 2616 (2003),<br></p>

<p>Applications Isonicotinamide is an isomeric analogue of nicotinamide and a metabolite of isonicotinic thioamide. Isonicotinamide strongly inducde apoptosis in human acute myelomonocytic leukemia cells, HL-60.<br>References Taguchi, H.: Furi Rajik. Rin., 14, 23 (1999); Golovinski, E. et al.: Comp. Rend. Acad. Bulg. Sci., 21, 375 (1968);<br></p>

<p>Applications Deschloroketamine Hydrochloride is a Ketamine (K165300) derivative currently made as a designer drug.<br>References Frison, Giampietro, et al.: Rapid Comm. in Mass Spec., 30(1), 151-160 (2016)<br></p>

<p>Applications 3,3’,5’-Triiodo-L-thyronine O-β-D-Glucuronide is the O-glucuronide derivative of 3,3’,5’-Triiodo-L-thyronine (T795350); a compound that is of interest for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus.<br>References Block, P.: J. Med. Chem., 19(8), 1067-1069 (1976); Shiba, T., &amp; Cahmann, H.J.: J.O.C., 29, 1652-1653 (1964)<br></p>

<p>Applications Insecticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Devine, G., et al.: Pestic. Sci., 55, 405 (1999), Ahmad, M., et al.: Pest Manag. Sci., 58, 203 (2002), El Kady, H., et al.: Pest Manag. Sci., 59, 865 (2003).<br></p>

<p>Applications 17-Hydroxy Pregnenolone, is a metabolite of Pregnenolone (P712200).<br>References Kramer, R., et al.: J. Steroid Biochemi., 18, 715 (1983), Hiwatashi, A., et al.: J. Biochem., 98, 619 (1985), Eiichi, T., et al.: J. Pharmacol. Sci., 95, 140 (2004),<br></p>

<p>Impurity Cyclophosphamide Impurity B<br>Stability Hygroscopic<br>Applications A metabolite of Cyclophosphamide (C988580). Cyclophosphamide Impurity B<br>References Joqueviel, C. et al.: Drug Metab. Dispos., 26, 418 (1998);<br></p>

<p>Applications 2-Methylcitric Acid is a metabolite of Citric Acid (C521000). It is formed from the condensation of propionoyl-CoA and oxaloacetic acid catalyzed by a citrate synthase enzyme.<br>References Allen, R. H., et al.: Metabolism, 42, 978 (1993)<br></p>

<p>Impurity Minoxidil EP Impurity E<br>Applications 2,4-Diamino-6-piperidinopyrimidine (Desoxyminoxidil) (Minoxidil EP Impurity E) is an analogue of Minoxidil (M345000).<br>References Cox, J., et al.: Adv. Drug Res., 5, 115 (1970), Watanabe., et al.: Microbiol. Immunol., 23, 1009 (1979), Nakai, H., et al.: J. Med. Chem., 31, 84 (1988), Shiraishi, M., et al.: J. Med. Chem., 32, 2214 (1989),<br></p>

<p>Stability Hygroscopic<br>Applications Eprinomectin-13CD3 is an isotopic analog of Eprinomectin (E590050), a mixture of semi-synthetic Avermectins.<br>References Jones, T.K., et al.: J. Agric. Food Chem., 42, 1786 (1994), Arena, J.P., et al.: J. Parasitol., 81, 286 (1995),<br></p>

<p>Impurity Lansoprazole EP Impurity C; USP Impurity B<br>Applications Lansoprazole Sulfide (Lansoprazole EP Impurity C; USP Impurity B) is a metabolite of Lansoprazole, as gastric pump inhibitor.<br>References Oie, et al.: J. Pharm. Sci., 68, 1203 (1979), Naesdal, J., et al.: Clin. Pharmacol. Ther., 40, 344 (1986), Dube, L., et al.: Biopharm. Drug Dispos., 10, 55 (1989), Barradell, L., et al.: Drugs, 44, 225 (1992),<br></p>

<p>Applications (E)-4-Hydroxy Tamoxifen-d5 is an labelled metabolite of Tamoxifen (T006000). A hydroxylated analogue of Tamoxifen with anti-estrogenic properties.<br>References Muerdter, T.E., et al.: Clin. Pharmacol. Therapeut., 89, 708 (2011); Dorchies, O. M., et al.: Am. J. Pathol., 182, 485 (2013);<br></p>

<p>Applications rac-1, 2-Didecanoyl-3-chloropropanediol belongs to a group of 3-Chloropropanediol fatty acid esters, which are contaminants found in edible oils and other food sources.<br>References Z. Zelinková, et al.: Food Addi. &amp; Conta., 23:12, 1290-1298 (2006)<br></p>

<p>Applications 5-Methyl-5-phenylhydantoin is a reactant for synthesis of beta-amino alcohols as inhibitors of anti-tubercular target N-acetyltransferase, chlorohydantoins and specific MMP inhibitors.<br>References Fullam, E., et al.: Bioorg. Med. Chem. Lett., 21, 1185 (2011); Whitehead, D., et al.: Tetrahedron Lett., 50, 3 (2009); Chollet, A., et al.: Bioorg. Med. Chem., 10, 531 (2002)<br></p>

<p>Applications Acrylamide-13C3 is carbon-13 labeled Acrylamide (A191300). Acrylamide is a chemical intermediate in production of polyacrylamides that are use in protein electrophoresis (PAGE), synthesis of dyes and copolymers for contact lenses. It is reasonably anticipated to be a human carcinogen (1,2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Mottram, D.S., et al.: Nature, 419, 448 (2002)(2) Tareke, E., et al.: J. Agric. Food Chem., 50, 4998 (2002)<br></p>

<p>Applications L-Lysine is an essential amino acid for human development. Lysine residues are useful in many cellular processes, due to their ability to accept a wide variety of post-translational modifications.<br>References Tosha, L. et. al.: Biochem. J. 435, 509 (2011);<br></p>

<p>Applications Propoxyphenyl Homohydroxysildenafil is an analogue of Homo Sildenafil (H615150) that may be used as a method for treating erectile dysfunction.<br></p>

<p>Stability Hygroscopic<br>Applications Rebaudioside C is a steviol glycoside used as a nutritive sweetener and may be used as a replacement for sugar in foods and beverages. Useful in the treatment of blood glucose sensitive diseases such as diabetes, high blood pressure, and obesity.<br>References Jooken, E. et al.: J. Agr. Food Chem., 60, 10606 (2012); Hellfritsch, C. et al.: J. Agr. Food. Chem., 60, 6782 (2012);<br></p>

<p>Stability Hygroscopic<br>Applications By-product in the preparation of a Lorazepam metabolite.<br></p>

<p>Applications Carbocisteine Sulfoxide is an impurity of the mucolytic agent Carbocisteine (C178760).<br>References Synge, R., et al.: Biochem. J., 64, 252 (1956); Waring, R., et al.: Drug Metab. Dispos., 10, 61 (1982); Mitchell, S., et al.: Xenobiotica, 14, 767 (1984);<br></p>

<p>Applications Tricaprylin is used in biological studies for fatty acid selectivity of lipases during acidolysis reaction between oleic acid and monoacid triacylglycerols.<br>References Karabulut, I., et al.: J. Agri. Food. Chem., 57, 10466 (2009);<br></p>

<p>Applications Creatine can be used in biological study of high fat diets with different ketogenic ratios on hippocampal accumulation of creatine.<br>References Skoczen, A., et al.: Spectrochim Acta A, 184, 13 (2017)<br></p>

<p>Applications Glutaric Acid is an organic acid found in human urine which may be used for the detection of metabolic or other health disorders.<br>References Christou, C., et. al.: J. Chromatogr. B. Anal. Tech. Biomed. Life Sci., 964, 195 (2014)<br></p>

<p>Applications Decyl Hexyl Phthalate is an phthalate esters used as plasticizers and additives. Used in toxiciology studies as well as risk assessment studies of food contamination that occurs via migration of phthalates into foodstuffs from food-contact materials (FCM).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Awad, N.E., et al.: Bull. Factul. Pharma., 40, 233 (2002); Harris, C.A., et al.: Environ. Health. Perspect., 105, 802 (1997);<br></p>

<p>Stability Hygroscopic<br>Applications Cantharidin is a well known natural compound produced by beetles of the Meloidae and Oedemeridae families. Insecticidal toxin. Apoptosis inducer in human H460 human lung cancer cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Khan, R. et al.: GMR. Gen. Mol. Res., 12, 4393 (2013); Hsia, T. et al.: Int. J. Onc., 45, 245 (2014);<br></p>

<p>Applications 4-Guanidinobutanoic Acid-D6 is an isotopic labeled compound of 4-Guanidinobutanoic acid (G825100). 4-Guanidinobutanoic acid is a guanidine derivative and a metabolite a found in urine, synthesized by gut microbiota.<br>References Yu, C.; et al.: Biomed. Chromatogr., 32 (2018); Lin, Z.; et al.: Scientific Reports, 8, 1 (2018).<br></p>

<p>Applications 4-Tolylsulfonamide is a carbonic anhydrase inhibitor used the synthesis of antiglaucoma and anticancer drugs.<br>References Vullo, D. et al.: Bioorg. Med. Chem. Lett., 15, 963 (2005); Vullo, D. et al.: Bioorg. Med. Chem. Lett., 15, 971 (2005);<br></p>

<p>Applications Tetrahydrofurfuryl alcohol (cas# 97-99-4) is a useful research chemical.<br></p>

<p>Applications Tyramine Hydrochloride is a naturally occurring monoamine derived from tyrosine. Neurotransmitter.<br>References Roy, K., et al.: J. Mol. Liq., 230, 104-112 (2017); Roy, M. N., et al.: Chem. Phys. Lett., 655-656, 43-50 (2016)<br></p>

<p>Applications 2-(4,6-Diphenyl-1,3,5-triazine-2-yl)-5-[(hexyl)oxy]phenol is used as a light stabilizer/UV absorber for polyethylene phthalate polymers intended for use in contact with food.<br>References Food and Drug Administration, HHS: Fed. Reg., 63, 43874 (1998); Fechine, G.J.M. et al.: Polym. Degrad. Stab., 75, 153 (2002);<br></p>

<p>Stability Hygroscopic<br>Applications Thiamine Nitrate is an orally administered vitamin. Thiamine is a essential nutrient required for carbohydrate metabolism and is involved in nerve function.<br>References Leuschner, J.: Arzneimittel-Forsch., 42, 114 (1992); Kawaski, T., et al.: Methods Enzymol., 122, 15 (1986); Mascher, H., et al.: J. Pharm. Sci., 82, 56 (1993)<br></p>

<p>Applications Di(n-butyl-d9) 1,10-Decanedioate is a useful isotopically labeled compound of Dibutyl Sebacate (D429525(P)). Dibutyl Sebacate (DBS) is a dibutyl ester of sebacic acid. Dibutyl Sebacate can be used for plastics in use in the food packaging industry, in plastics used for medical devices, and for pharmaceutical applications. Dibutyl Sebacate is also used as a desensitizer in Otto fuel II, a torpedo monopropellant.<br>References Eriksson, M., et al.: Plant Physiol., 132, 732 (2003), ,,Beuve, N., et al.: Plant Cell Environ., 27, 1035 (2004),<br></p>

<p>Applications b-Adrenergic agonist. Zipaterol, is used to promote growth. Zilpaterol is used to increase the size of cattle.<br>References Shelver, W.L., et al.: J. Agric. Food Chem., 52, 2159 (2004),<br></p>

<p>Applications A terpenic ketone; odorant in fruits, vegetables, honey, wine and beer.<br>References Sen, A., et al.: J. Agric. Food Chem., 39, 757 (1991), Chevance, F., et al.: J. Agric. Food Chem., 50, 3818 (2002), Daniel, M.A., et al.: J. Agric. Food Chem., 52, 8127 (2004)<br></p>

<p>Applications Vinyltrimethoxysilane (cas# 2768-02-7) is a useful research chemical.<br></p>

<p>Applications Dimethyl Phalate is the methyl ester of phthalic acid. Dimethyl phthalate is an ectoparasiticide and has many other uses, including in solid rocket propellants, plastics, and insect repellents.<br>References Iselin, B., et al.: Helv. Chim. Acta., 40, 373 (1957),<br></p>

<p>Applications 4-(Trifluoromethyl)nicotinoyl Glycine is a metabolite of Flonicamid (F405710); a novel insecticide with rapid inhibitory effect against aphid feeding.<br>References Lee, Sung Woo., et al.: J. Chrom. A., 1218(28), 4366-4377 (2011); Hengel, Matt J., et al.: J. Agr. Food Chem., 55(20), 8033-8039 (2007); Morita, M., et al.: Pest. Manag. Sci.,63, 969 (2007); Sabatino, L., et al.: Food. Additive. Contamin., 6, 11 (2013)<br></p>

<p>Applications trans-p-Coumaric Acid is the E-isomer of p-Coumaric Acid (C755365), a hydroxy derivative of Cinnamic Acid with antioxidant properties. p-Coumaric acid is a is a major component of lignocellulose. Studies suggest that p-Coumaric Acid may reduce the risk of cancer by reducing the formation of carcinogenic nitrosamines.<br>References Kikugawa, K. et al.: J. Agric. Food Chem., 1, 780 (1983); Ferguson, L.R. et al.: Mol. Nutrit. Food Res., 585 (2005); Chung, F.L. et al.: IARC Sci. Pub., 57, 797 (1984);<br></p>

<p>Applications Bisphenol B-d8 is the isotope labelled analog of Bisphenol B. Bisphenol B, is the analouge of Bisphenol A (B519495), which is used to make certain plastic an epoxy resins. BPA and its analogs, are also shown to activate human pregnane X receptor (PXR), a nuclear receptor that functions as a master regulator of xenobiotic metabolism.<br>References Yipeng, S., et al.: Env Hea. Pers., 120, 399 (2012); Krishnan, A.V., et al.: Endocrinology, 132, 2279 (1993); Steinmetz, R., et al.: Trends Endocrinol. Metab., 9, 124 (1998), Petersen, H., et al.: Eur. Food Res. Technol., 216, 355 (2003);<br></p>