Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(111 prodotti)
- CDK(526 prodotti)
- Arresto del ciclo cellulare(4 prodotti)
- Chk(46 prodotti)
- DYRK(49 prodotti)
- Dynamin(26 prodotti)
- Ferroptosi(225 prodotti)
- HSP(179 prodotti)
- Integrina(256 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(19 prodotti)
- Microtubulo associato(283 prodotti)
- PKC(111 prodotti)
- PLK(25 prodotti)
- ROCK(66 prodotti)
- Rho(2 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
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Trovati 3756 prodotti di "Ciclo cellulare/Checkpoint"
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Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formula:C32H46O8Purezza:97.1% - 99.33%Colore e forma:SolidPeso molecolare:558.70Y16
CAS:Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Formula:C24H20N2O3Purezza:98.26% - 99.85%Colore e forma:SolidPeso molecolare:384.43MC180295
CAS:<p>MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.</p>Formula:C17H18N4O3SPurezza:99.84%Colore e forma:SolidPeso molecolare:358.41Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Formula:C27H41N9O7Purezza:95.29% - >99.99%Colore e forma:SolidPeso molecolare:603.67CID44216842
CAS:CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Formula:C22H20BrN3O3SPurezza:99.66%Colore e forma:SolidPeso molecolare:486.386-AZATHYMINE
CAS:6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.Formula:C4H5N3O2Purezza:99.47%Colore e forma:SolidPeso molecolare:127.13-Methylcytidine
CAS:<p>3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.</p>Formula:C10H15N3O5Purezza:99.52%Colore e forma:SolidPeso molecolare:257.24(1E)-CFI-400437 dihydrochloride
CAS:(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.Formula:C29H30Cl2N6O2Purezza:97.08%Colore e forma:SolidPeso molecolare:565.5TH-257
CAS:TH-257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM).Formula:C24H26N2O3SPurezza:98.23%Colore e forma:SolidPeso molecolare:422.54CRT0044876
CAS:CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.Formula:C9H6N2O4Purezza:98.27% - 98.98%Colore e forma:Brown PowderPeso molecolare:206.155-Fluoroorotic acid
CAS:5-Fluoroorotic acid is an inhibitor of thymidylate synthase.Formula:C5H3FN2O4Purezza:99.7% - >99.99%Colore e forma:White To Pale Yellow PowderPeso molecolare:174.09RI-2
CAS:RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.Formula:C21H18Cl2N2O4Purezza:99.63% - 99.86%Colore e forma:SolidPeso molecolare:433.28Quarfloxin
CAS:<p>Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.</p>Formula:C35H33FN6O3Purezza:99.77%Colore e forma:SolidPeso molecolare:604.67Ro5-3335
CAS:Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.Formula:C13H10ClN3OPurezza:99.42% - 99.87%Colore e forma:SolidPeso molecolare:259.69XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formula:C22H31N9OPurezza:99.07%Colore e forma:SolidPeso molecolare:437.54Tozasertib
CAS:Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).Formula:C23H28N8OSPurezza:99.99%Colore e forma:SolidPeso molecolare:464.59SAR-020106
CAS:SAR-020106 is a potent, ATP-competitive, and selective CHK1 inhibitor with an IC50 of 13.3 nmol/L on the isolated human enzyme.Formula:C19H19ClN6OPurezza:97.78%Colore e forma:SolidPeso molecolare:382.85Tipiracil hydrochloride
CAS:Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI).Formula:C9H12Cl2N4O2Purezza:98.13% - ≥95%Colore e forma:SolidPeso molecolare:279.12THZ2
CAS:THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC).Formula:C31H28ClN7O2Purezza:98.28%Colore e forma:SolidPeso molecolare:566.05Madrasin
CAS:<p>Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.</p>Formula:C16H17N5O2Purezza:99.06% - 99.61%Colore e forma:SolidPeso molecolare:311.34Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Formula:C16H18N2O2SPurezza:98.07%Colore e forma:SolidPeso molecolare:302.39SCH900776 (S-isomer)
CAS:SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).Formula:C15H18BrN7Purezza:99.88%Colore e forma:SolidPeso molecolare:376.25THZ531
CAS:THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).Formula:C30H32ClN7O2Purezza:97.17% - 99.86%Colore e forma:SolidPeso molecolare:558.07RAD51-IN-1
CAS:Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.Formula:C22H16ClN3OPurezza:99.95%Colore e forma:SolidPeso molecolare:373.83CBFβ Inhibitor
CAS:CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.Formula:C12H14N2OSPurezza:96.50%Colore e forma:SolidPeso molecolare:234.32NITD-2
CAS:NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Formula:C23H19N3O4SPurezza:98.03% - 99.46%Colore e forma:SolidPeso molecolare:433.48Monastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formula:C14H16N2O3SPurezza:98.02% - 98.59%Colore e forma:SolidPeso molecolare:292.35AUZ 454
CAS:AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.Formula:C24H26F3N7O2Purezza:99.59%Colore e forma:SolidPeso molecolare:501.5CX-5461
CAS:CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.Formula:C27H27N7O2SPurezza:95.44% - 99.4%Colore e forma:SolidPeso molecolare:513.61BVDV-IN-1
CAS:<p>BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.</p>Formula:C20H22N4OPurezza:98.43%Colore e forma:SolidPeso molecolare:334.41PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formula:C25H26F3N5O3Purezza:99.14% - 99.75%Colore e forma:SolidPeso molecolare:501.5OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Formula:C30H30F3N5OPurezza:98.69%Colore e forma:SolidPeso molecolare:533.59HMN-176
CAS:<p>HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).</p>Formula:C20H18N2O4SPurezza:98.92% - 98.99%Colore e forma:SolidPeso molecolare:382.43PTC-209
CAS:PTC-209 is a potent and selective BMI-1 inhibitor.Formula:C17H13Br2N5OSPurezza:99.43% - 99.887%Colore e forma:SolidPeso molecolare:495.19PHA-680632
CAS:<p>PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.</p>Formula:C28H35N7O2Purezza:98.2%Colore e forma:SolidPeso molecolare:501.62Purvalanol B
CAS:Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)Formula:C20H25ClN6O3Purezza:98.95%Colore e forma:SolidPeso molecolare:432.9ARQ 621
CAS:ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.Formula:C28H24Cl2FN5O2Purezza:97.01% - 98.38%Colore e forma:SolidPeso molecolare:552.43Palbociclib monohydrochloride
CAS:<p>Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases</p>Formula:C24H29N7O2·HClPurezza:99.73% - >99.99%Colore e forma:SolidPeso molecolare:483.99Nolatrexed
CAS:Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.Formula:C14H12N4OSPurezza:97.53%Colore e forma:SolidPeso molecolare:284.34Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activationFormula:C76H121N19O25SPurezza:98.96%Colore e forma:SolidPeso molecolare:1732.95CVT-313
CAS:CVT-313 (NG-26) is a potent, selective, reversible, and ATP-competitive inhibitor.Formula:C20H28N6O3Purezza:97.46% - 97.97%Colore e forma:SolidPeso molecolare:400.47GW779439X
CAS:GW779439X is an inhibitor of CDK.Formula:C22H21F3N8Purezza:97.87%Colore e forma:SolidPeso molecolare:454.45Raltitrexed
CAS:Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of L1210 cell growth.Formula:C21H22N4O6SPurezza:98.99% - 99.29%Colore e forma:Yellow Crystalline PowderPeso molecolare:458.49AMG 900
CAS:<p>AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.</p>Formula:C28H21N7OSPurezza:98.4% - 99.51%Colore e forma:SolidPeso molecolare:503.58MKC3946
CAS:MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.Formula:C21H20N2O3SPurezza:99.65%Colore e forma:SolidPeso molecolare:380.462′-O-Methylcytidine
CAS:<p>2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.</p>Formula:C10H15N3O5Purezza:99.72%Colore e forma:SolidPeso molecolare:257.24Palbociclib Isethionate
CAS:<p>Palbociclib Isethionate (PD 0332991 isethionate) 是一种高选择性的CDK4/6抑制剂，IC50为11 nM 和16 nM。它对一组 36 种额外的蛋白激酶没有抑制作用。</p>Formula:C24H29N7O2·C2H6O4SPurezza:99.01% - 99.27%Colore e forma:SolidPeso molecolare:573.66ML264
CAS:ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Formula:C17H21ClN2O4SPurezza:99.33% - 99.45%Colore e forma:SolidPeso molecolare:384.88CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formula:C22H23Cl2N7Purezza:96.2% - 99.81%Colore e forma:SolidPeso molecolare:456.37Ara-G
CAS:<p>Ara-G, a deoxyguanosine analog, inhibits DNA synthesis, targeting T cell leukemia by converting to araGTP.</p>Formula:C10H13N5O5Purezza:98.74%Colore e forma:Slightly Off White To White PowderPeso molecolare:283.24Didox
CAS:Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.Formula:C7H7NO4Purezza:99.83%Colore e forma:SolidPeso molecolare:169.13T56-LIMKi
CAS:T56-LIMKi (T5601640) is a selective inhibitor of LIMK2.Formula:C19H14F3N3O3Purezza:98.39% - 99.57%Colore e forma:SolidPeso molecolare:389.33TP-353
CAS:TP-353 (EOS-61973) is a CDK7 inhibitor.Formula:C35H30FNO3Purezza:99.12%Colore e forma:SolidPeso molecolare:531.62ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formula:C21H25N7Purezza:97.63% - ≥95%Colore e forma:SolidPeso molecolare:375.47BI-1347
CAS:BI-1347 is a potent, selective inhibitor of CDK8/cyclinC (IC50: 1 nM). It shows tumor growth inhibition in an in vivo xenograft model.Formula:C22H20N4OPurezza:96.7% - 99.63%Colore e forma:SolidPeso molecolare:356.42COH29
CAS:COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.Formula:C22H16N2O5SPurezza:97.04% - 98.92%Colore e forma:SolidPeso molecolare:420.44Fialuridine
CAS:<p>Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.</p>Formula:C9H10FIN2O5Purezza:99.71% - 99.88%Colore e forma:Less Crystals Colourless CrystalsPeso molecolare:372.09SRI-29329
CAS:SRI-29329 is a potent, specific inhibitor of CDC-like kinase (with IC50 of 78 nM, 16 nM and 86 nM for CLK1, CLK2 and CLK4, respectively).Formula:C20H26ClN7Purezza:99.18%Colore e forma:SolidPeso molecolare:399.92NSC23005
CAS:<p>NSC23005 sodium is a p18INK inhibitor with potently promoted hematopoietic stem cell (HSC) expansion (ED50: 5.21 nM).</p>Formula:C13H17NO4SPurezza:>99.99%Colore e forma:SolidPeso molecolare:283.34Lifitegrast
CAS:<p>Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.</p>Formula:C29H24Cl2N2O7SPurezza:99.39% - 99.66%Colore e forma:SolidPeso molecolare:615.48TH287 hydrochloride
CAS:<p>TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.</p>Formula:C11H11Cl3N4Purezza:>99.99%Colore e forma:SolidPeso molecolare:305.59ILK-IN-3
CAS:ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Formula:C10H12N6OPurezza:99.69%Colore e forma:SolidPeso molecolare:232.24Trilaciclib
CAS:Trilaciclib is a short-acting, orally effective CDK4/6 inhibitor with IC₅₀ values of 1 nM and 4 nM respectively. enhances antitumour immunity.Formula:C24H30N8OPurezza:99.624%Colore e forma:SolidPeso molecolare:446.55Barasertib-HQPA
CAS:<p>Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.</p>Formula:C26H30FN7O3Purezza:98.43% - 99.29%Colore e forma:SolidPeso molecolare:507.56N6,N6-Dimethyladenosine
CAS:<p>N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.</p>Formula:C12H17N5O4Purezza:98.79%Colore e forma:White PowderPeso molecolare:295.29Proguanil
CAS:Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the DHFR enzyme .Formula:C11H16ClN5Purezza:99.6%Colore e forma:SolidPeso molecolare:253.73N6-Methyl-2'-O-methyladenosine
CAS:N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound foundFormula:C12H17N5O4Purezza:99.97%Colore e forma:SolidPeso molecolare:295.29Bexotegrast
CAS:Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Formula:C27H36N6O3Purezza:99.53%Colore e forma:SolidPeso molecolare:492.612'-O-(2-Methoxyethyl)adenosine
CAS:2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Formula:C13H19N5O5Purezza:99.35%Colore e forma:SolidPeso molecolare:325.325'-O-DMT-N4-Bz-5-Me-dC
CAS:5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.Formula:C38H37N3O7Purezza:98.88%Colore e forma:SolidPeso molecolare:647.725-Bromouridine
CAS:5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.Formula:C9H11BrN2O6Purezza:99.89%Colore e forma:White PowderPeso molecolare:323.1PDD00017273
CAS:PDD00017273 is a radiosensitizing PARG) inhibitor with antitumor or activity for the study of epithelial ovaries.Formula:C23H26N6O4S2Purezza:99.14% - 99.21%Colore e forma:SolidPeso molecolare:514.62Braco-19
CAS:<p>Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in human glioblastoma cells.</p>Formula:C35H43N7O2Purezza:97.01%Colore e forma:SolidPeso molecolare:593.76CDK12-IN-5
CAS:CDK12-IN-5 is a potent CDK12 inhibitor with potential anticancer and antitumor activity, and can be used orally in the study of breast and ovarian cancer.Formula:C18H15F5N8OPurezza:99.37%Colore e forma:SolidPeso molecolare:454.365-Bromo-2',3',5'-tri-O-acetyluridine
CAS:5-Bromo-2',3',5'-tri-O-acetyluridine is a purine nucleoside analog that can be used to explore explore improve Parkinson's disease.Formula:C15H17BrN2O9Purezza:99%Colore e forma:SolidPeso molecolare:449.21ARB-272572
CAS:ARB-272572 is a PD-L1 signaling inhibitor that produces immunostimulatory activity in human primary cells.Formula:C32H36N6O4Purezza:97.36% - 98.07%Colore e forma:SolidPeso molecolare:568.67Rabacfosadine
CAS:Rabacfosadine (GS-9219) is a novel prodrug of PMEG, an acyclic nucleotide phosphonate, with antitumor activity for the study of lymphoma.Formula:C21H35N8O6PPurezza:99.06% - 99.37%Colore e forma:SolidPeso molecolare:526.532'-C-β-Methylguanosine
CAS:<p>2'-C-beta-Methylguanosine (2'-C-Methylguanosine), with antiviral activity, inhibits dengue virus 2.</p>Formula:C11H15N5O5Purezza:99.37%Colore e forma:SolidPeso molecolare:297.27RO0270608
CAS:RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Formula:C24H19Cl3N2O4Purezza:98.26%Colore e forma:SolidPeso molecolare:505.78DS44960156
CAS:DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.Formula:C20H15NO5Purezza:99.13%Colore e forma:SolidPeso molecolare:349.342'-Deoxy-N2-methylguanosine
CAS:2'-Deoxy-N2-methylguanosine is a purine nucleoside analog that can be used as a chemical probe to study DNA-protein interactions.Formula:C11H15N5O4Purezza:99.79%Colore e forma:SolidPeso molecolare:281.27LSN2839567
CAS:<p>LSN2839567 (Abemaciclib metabolite M2) is a CDK4 and CDK6 inhibitor with anticancer activity, inhibits CDK9, and can be used in breast cancer research.</p>Formula:C25H28F2N8Purezza:99.14%Colore e forma:SolidPeso molecolare:478.542'-O-Methyl-2-thiouridine
CAS:2'-O-Methyl-2-thiouridine, a purine nucleoside analog present in synthetic thermophilic bacterial tRNAs, is more selective for A than unmodified U.Formula:C10H14N2O5SPurezza:99.89%Colore e forma:SolidPeso molecolare:274.292'-Deoxy-N4-methylcytidine
CAS:2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) is a purine nucleoside analog with potential antitumor activity for the study of apoptosis.Formula:C10H15N3O4Purezza:99.61%Colore e forma:SolidPeso molecolare:241.243'-Deoxy-3'-fluoroadenosine
CAS:3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borneFormula:C10H12FN5O3Purezza:99.84%Colore e forma:SolidPeso molecolare:269.23PolQi2
CAS:PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.Formula:C21H16ClN5O3SPurezza:99.19%Colore e forma:SolidPeso molecolare:453.95-Hydroxyuridine
CAS:5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue with potential antitumour activity, showing cytotoxicity against human colon adenocarcinoma cell lines.Formula:C9H12N2O7Purezza:98.76%Colore e forma:SolidPeso molecolare:260.29-(β-D-Xylofuranosyl)adenine
CAS:9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine hasFormula:C10H13N5O4Purezza:99.97%Colore e forma:SolidPeso molecolare:267.24Z62954982
CAS:Z62954982 (ZINC08010136) is a Rac1 inhibitor that inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arteriesFormula:C20H21N3O5SPurezza:98.28%Colore e forma:SolidPeso molecolare:415.462'-Deoxy-2-iodoadenosine
CAS:2'-Deoxy-2-iodoadenosine is a purine nucleoside analog with potential antimicrobial, antioxidant and anti-leukemic activities.Formula:C10H12IN5O3Purezza:99.37%Colore e forma:SolidPeso molecolare:377.142',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS:2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication，AIDS and herpes.Formula:C21H40N2O6Si2Purezza:99.88%Colore e forma:SolidPeso molecolare:472.72N6-(p-Methoxybenzyl)adenosine
CAS:Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; plant growth regulator, plant hormoneFormula:C18H21N5O5Purezza:99.79%Colore e forma:SolidPeso molecolare:387.39N6-(2-Hydroxyethyl)adenosine
CAS:<p>N6-(2-Hydroxyethyl)adenosine is a sedative, Ca2+ antagonist, and anti-inflammatory, affecting brain and heart blood flow.</p>Formula:C12H17N5O5Purezza:99.4%Colore e forma:SolidPeso molecolare:311.29O6-Methyldeoxy guanosine
CAS:O6-Methyldeoxy guanosine, a deoxypurine nucleoside, is a weak inhibitor of the removal of O6-methylguanine from methylated DNA by rat liver enzymes in vitro.Formula:C11H15N5O4Purezza:99.57%Colore e forma:SolidPeso molecolare:281.27P-2'-deoxyribose
CAS:P-2'-deoxyribose (P-Nucleoside) is a deoxyribose that is widely found in organisms.Formula:C11H15N3O5Purezza:99.71%Colore e forma:SolidPeso molecolare:269.25Levomefolate sodium
CAS:Levomefolate sodium (L-5-MTHF sodium) is a dietary supplement that can be used to study megaloblastic anemia and neurological disorders.Formula:C20H23N7Na2O6Purezza:98.7%Colore e forma:SolidPeso molecolare:503.42Mps1-IN-2
CAS:Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.Formula:C26H36N6O3Purezza:96.24% - 99.75%Colore e forma:SolidPeso molecolare:480.6MK-5108
CAS:MK-5108 (VX-689) is a highly potent and specific Aurora-A kinase inhibitor with an IC50 value of 0.064 nM.Formula:C22H21ClFN3O3SPurezza:99.22%Colore e forma:SolidPeso molecolare:461.94SCH-1473759 hydrochloride
CAS:SCH-1473759 hydrochloride is an inhibitor of aurora(aurora A and B with IC50s of 4 and 13 nM, respectively).Formula:C20H27ClN8OSPurezza:98.29%Colore e forma:SolidPeso molecolare:463Gresonitamab
CAS:Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.Colore e forma:Liquid
