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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3730 prodotti di "Ciclo cellulare/Checkpoint"

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  • Antibacterial agent 144


    Antibacterial Agent 144 (compound 8e) exhibits superior efficacy against multi-resistant Staphylococcus aureus compared to Chloromycin and Amoxicillin.
    Formula:C26H23N7O3
    Colore e forma:Solid
    Peso molecolare:481.51
  • (S)-DI-87

    CAS:
    <p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor,reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>
    Formula:C23H30N6O3S2
    Purezza:99.42%
    Colore e forma:Soild
    Peso molecolare:502.65
  • PROTAC CDK9 degrader-2

    CAS:
    PROTAC CDK9 degrader-2, potent, selective, IC50 17 μM in MCF-7, wogonin-derived, targets CRBN.
    Formula:C39H36N6O10
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:748.74
  • Ac-dA Phosphoramidite

    CAS:
    Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.
    Formula:C42H50N7O7P
    Colore e forma:Solid
    Peso molecolare:795.878
  • Eesperamicin A1

    CAS:
    Esperamicin A1, a powerful antitumor drug, comes from Actinomadura verrucosospora.
    Formula:C59H80N4O22S4
    Colore e forma:Solid
    Peso molecolare:1325.54
  • Mumefural

    CAS:
    <p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>
    Formula:C12H12O9
    Colore e forma:Solid
    Peso molecolare:300.22
  • Obtustatin


    <p>Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.</p>
    Formula:C184H284N52O57S8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:4393.07
  • Brr2-IN-2


    <p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>
    Formula:C21H25FN4O2
    Colore e forma:Solid
    Peso molecolare:384.45
  • Pseudorabies virus-IN-1


    <p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>
    Formula:C27H23ClF2N4O2
    Colore e forma:Solid
    Peso molecolare:508.947
  • 5'-O-DMT-ibu-dC

    CAS:
    5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.
    Formula:C34H37N3O7
    Colore e forma:Solid
    Peso molecolare:599.67
  • WAY-647802

    CAS:
    <p>WAY-647802 is a CDK inhibitor.</p>
    Formula:C11H14N4O3
    Purezza:99.53%
    Colore e forma:Solid
    Peso molecolare:250.25
  • Cytarabine triphosphate

    CAS:
    Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.
    Formula:C9H16N3O14P3
    Colore e forma:Solid
    Peso molecolare:483.16
  • Gantofiban

    CAS:
    Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.
    Formula:C21H29N5O6
    Purezza:99.57%
    Colore e forma:Solid
    Peso molecolare:447.48
  • Nusinersen

    CAS:
    <p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>
    Purezza:98.62%
    Colore e forma:Solid
  • Chrysomycin A

    CAS:
    Chrysomycin A is an antibiotic that can be derived from Streptomyces.
    Formula:C28H28O9
    Colore e forma:Solid
    Peso molecolare:508.52
  • (+)-Glaucarubinone


    (+)-Glaucarubinone is a natural product that can be used as a reference standard.
    Formula:C25H34O10
    Colore e forma:Solid
    Peso molecolare:494.537
  • 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

    CAS:
    dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.
    Formula:C10H14N5Na2O8P
    Colore e forma:Solid
    Peso molecolare:409.202
  • 5'(R)-C-Methyl-5-fluorouridine


    5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.
    Formula:C10H13FN2O6
    Colore e forma:Solid
    Peso molecolare:276.22
  • SNX7

    CAS:
    SNX7 (WAY-323879) inhibits CDKI pathway; useful for studying aging and related diseases.
    Formula:C15H14N2O
    Purezza:99.96%
    Colore e forma:Solid
    Peso molecolare:238.28
  • PLK1-IN-2

    CAS:
    PLK1-IN-2 is a PLK1 kinase inhibitor with an IC 50 value of 0.384 μM.
    Formula:C24H27FN8OS
    Colore e forma:Solid
    Peso molecolare:494.59