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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3730 prodotti di "Ciclo cellulare/Checkpoint"

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  • Pseudorabies virus-IN-1
    Targetmol
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    Pseudorabies virus-IN-1

    <p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>
    Formula:C27H23ClF2N4O2
    Colore e forma:Solid
    Peso molecolare:508.947

    Ref: TM-T206101

  • Logo CymitQuimica
    Targetmol
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    Catumaxomab

    CAS:
    <p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>
    Purezza:95%
    Colore e forma:Liquid

    Ref: TM-T78307

  • Logo CymitQuimica
    Targetmol
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    STX-100

    PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.
    Purezza:97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)
    Colore e forma:Odour Liquid

    Ref: TM-T9901A-062

  • JAMM protein inhibitor 2 
    Targetmol
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    JAMM protein inhibitor 2 

    CAS:
    JAMM inhibitor 2 targets thrombin, Rpn11, MMP2 with IC50s 10, 46, 89 μM, aids cancer research.
    Formula:C21H26N2O2
    Purezza:98.57%
    Colore e forma:Solid
    Peso molecolare:338.44

    Ref: TM-T9892

  • Mumefural
    Targetmol
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    Mumefural

    CAS:
    <p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>
    Formula:C12H12O9
    Colore e forma:Solid
    Peso molecolare:300.22

    Ref: TM-T75689

  • Logo CymitQuimica
    Targetmol
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    Obtustatin

    <p>Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.</p>
    Formula:C184H284N52O57S8
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:4393.07

    Ref: TM-TP1974

  • 5-Iminodaunorubicin
    Targetmol
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    5-Iminodaunorubicin

    CAS:
    5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.
    Formula:C27H30N2O9
    Colore e forma:Solid
    Peso molecolare:526.54

    Ref: TM-T72467

  • Logo CymitQuimica
    Targetmol
    + Info

    N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine

    <p>N4-Benzoyl-3'-O-DMT cytidine analog inhibits DNA methyltransferases like Zebularine.</p>
    Formula:C41H43N3O9
    Colore e forma:Solid
    Peso molecolare:721.79

    Ref: TM-T75224

  • SMS 121
    Targetmol
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    SMS 121

    CAS:
    SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.
    Formula:C20H21NO5
    Purezza:98.29%
    Colore e forma:Soild
    Peso molecolare:355.38

    Ref: TM-T205876

  • 6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
    Targetmol
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    6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

    CAS:
    6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a pyrimidine nucleoside analog, exhibits a broad spectrum of biochemical and
    Formula:C11H15N5O4
    Colore e forma:Solid
    Peso molecolare:281.27

    Ref: TM-T75185

  • Logo CymitQuimica
    Targetmol
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    Farletuzumab

    CAS:
    <p>Farletuzumab (MORAb-003), a humanized antibody, inhibits FRα-expressing cell growth for cancer research.</p>
    Purezza:> 95%
    Colore e forma:Liquid
    Peso molecolare:145.36 kDa

    Ref: TM-T76720

  • CTP Synthetase-IN-1 Ammonium salt
    Targetmol
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    CTP Synthetase-IN-1 Ammonium salt

    <p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>
    Formula:C20H22F3N7O3S2
    Purezza:99.97%
    Colore e forma:Solid
    Peso molecolare:529.56

    Ref: TM-T72505L

  • TAS-119
    Targetmol
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    TAS-119

    CAS:
    TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95
    Formula:C23H22Cl2FN5O3
    Purezza:99.65%
    Colore e forma:Solid
    Peso molecolare:506.36

    Ref: TM-T34787

  • WAY-647802
    Targetmol
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    WAY-647802

    CAS:
    <p>WAY-647802 is a CDK inhibitor.</p>
    Formula:C11H14N4O3
    Purezza:99.53%
    Colore e forma:Solid
    Peso molecolare:250.25

    Ref: TM-T9971

  • Eesperamicin A1
    Targetmol
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    Eesperamicin A1

    CAS:
    Esperamicin A1, a powerful antitumor drug, comes from Actinomadura verrucosospora.
    Formula:C59H80N4O22S4
    Colore e forma:Solid
    Peso molecolare:1325.54

    Ref: TM-T41140

  • Echistatin
    Targetmol
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    Echistatin

    CAS:
    Potent αVβ3 integrin blocker, stops osteoclast binding & bone loss, hinders platelet aggregation. Ki=0.27 nM, IC50s: 0.1 nM (bone), 30 nM (platelets).
    Formula:C217H341N71O74S9
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:5417.1

    Ref: TM-TP2098

  • Clofarabine-5'-diphosphate
    Targetmol
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    Clofarabine-5'-diphosphate

    CAS:
    Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.
    Formula:C10H13ClFN5O9P2
    Colore e forma:Solid
    Peso molecolare:463.64

    Ref: TM-T203181

  • Erythromycin thiocyanate
    Targetmol
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    Erythromycin thiocyanate

    CAS:
    Erythromycin thiocyanate, a macrolide from Streptomyces erythreus, binds 50S ribosomes, halting protein synthesis in bacteria.
    Formula:C38H68N2O13S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:793.02

    Ref: TM-T11233

  • Logo CymitQuimica
    Targetmol
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    5'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite

    5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.
    Formula:C44H49F2N4O7P
    Colore e forma:Solid
    Peso molecolare:814.85

    Ref: TM-T75190

  • NUAK1-IN-1
    Targetmol
    + Info

    NUAK1-IN-1

    NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.
    Formula:C25H30N6O
    Colore e forma:Solid
    Peso molecolare:430.545

    Ref: TM-T205625