Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(545 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(48 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(232 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(272 prodotti)
- PKC(124 prodotti)
- PLK(25 prodotti)
- ROCK(62 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3839 prodotti di "Ciclo cellulare/Checkpoint"
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E7820
CAS:E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
Formula:C17H12N4O2SPurezza:98.31% - 99.11%Colore e forma:SolidPeso molecolare:336.37EN4
CAS:EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC.Formula:C25H24N2O4Purezza:98.51%Colore e forma:SolidPeso molecolare:416.47NG 52
CAS:NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.Formula:C16H19ClN6OPurezza:98% - 99.34%Colore e forma:SolidPeso molecolare:346.81THZ1
CAS:THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.Formula:C31H28ClN7O2Purezza:97.42% - 99.27%Colore e forma:SolidPeso molecolare:566.05MLN8054
CAS:MLN8054 is a potent and selective Aurora A kinase inhibitor with an IC50 of 4 nM.Formula:C25H15ClF2N4O2Purezza:98.07% - 98.26%Colore e forma:SolidPeso molecolare:476.86Ref: TM-T6315
1mg50,00€2mg67,00€5mg84,00€10mg120,00€25mg220,00€50mg356,00€100mg537,00€1mL*10mM (DMSO)88,00€CCT245737
CAS:CCT245737 is an orally active, selective Chk1 inhibitor, and is >1,000-fold selective over CHK2 and CDK1.Cost-effective and quality-assured.Formula:C16H16F3N7OPurezza:98.28% - 99.93%Colore e forma:SolidPeso molecolare:379.34Ref: TM-T7080
1mg37,00€2mg49,00€5mg79,00€10mg113,00€25mg213,00€50mg350,00€100mg523,00€1mL*10mM (DMSO)87,00€Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formula:C32H46O8Purezza:97.1% - 99.33%Colore e forma:SolidPeso molecolare:558.70Y16
CAS:Y16 is a G protein-coupled Rho GEFs inhibitor and also a specific inhibitor of LARG with a Kd of 76 nM.Cost-effective and quality-assured.Formula:C24H20N2O3Purezza:98.26% - 99.85%Colore e forma:SolidPeso molecolare:384.43Ref: TM-T3553
1mg34,00€2mg48,00€5mg70,00€10mg109,00€25mg177,00€50mg263,00€100mg389,00€1mL*10mM (DMSO)77,00€MC180295
CAS:MC180295 ((rel)-MC180295) is a novel potent, highly selective CDK9 inhibitor (IC50: 5 nM), displays >22-fold selectivity over other CDKs.Formula:C17H18N4O3SPurezza:99.84%Colore e forma:SolidPeso molecolare:358.41Ref: TM-T5533
1mg52,00€5mg124,00€10mg177,00€25mg301,00€50mg424,00€100mg605,00€200mg797,00€1mL*10mM (DMSO)136,00€Cyclo(-RGDfK)
CAS:Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Formula:C27H41N9O7Purezza:95.29% - >99.99%Colore e forma:SolidPeso molecolare:603.67CID44216842
CAS:CID44216842 is a potent Cdc42-selective inhibitor with EC50: 1.0μM (WT), 1.2μM (Q61L) in GTP assay; 0.3μM (WT), 0.5μM (Q61L) in GDP assay. Use as a probe.Formula:C22H20BrN3O3SPurezza:99.66%Colore e forma:SolidPeso molecolare:486.38Ref: TM-T8930
2mg34,00€5mg50,00€10mg85,00€25mg159,00€50mg244,00€100mg359,00€200mg512,00€1mL*10mM (DMSO)55,00€6-AZATHYMINE
CAS:6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.Formula:C4H5N3O2Purezza:99.47%Colore e forma:SolidPeso molecolare:127.13-Methylcytidine
CAS:3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.Formula:C10H15N3O5Purezza:99.52%Colore e forma:SolidPeso molecolare:257.24(1E)-CFI-400437 dihydrochloride
CAS:(1E)-CFI-400437 dihydrochloride (CFI-400437 dihydrochloride) is a selective and potent polo-like kinase 4 (PLK4) inhibitor.Formula:C29H30Cl2N6O2Purezza:97.08%Colore e forma:SolidPeso molecolare:565.5Ref: TM-T22288
1mg77,00€5mg160,00€10mg236,00€25mg394,00€50mg550,00€100mg782,00€1mL*10mM (DMSO)197,00€TH-257
CAS:TH-257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM).Formula:C24H26N2O3SPurezza:98.23%Colore e forma:SolidPeso molecolare:422.54CRT0044876
CAS:CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.Formula:C9H6N2O4Purezza:98.27% - 98.98%Colore e forma:Brown PowderPeso molecolare:206.155-Fluoroorotic acid
CAS:5-Fluoroorotic acid is an inhibitor of thymidylate synthase.Formula:C5H3FN2O4Purezza:99.7% - >99.99%Colore e forma:White To Pale Yellow PowderPeso molecolare:174.09RI-2
CAS:RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.Formula:C21H18Cl2N2O4Purezza:99.63% - 99.86%Colore e forma:SolidPeso molecolare:433.28Ref: TM-T2628
1mg70,00€2mg92,00€5mg152,00€10mg266,00€25mg413,00€50mg605,00€100mg863,00€1mL*10mM (DMSO)166,00€Quarfloxin
CAS:Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.Formula:C35H33FN6O3Purezza:99.77%Colore e forma:SolidPeso molecolare:604.67Ref: TM-T16703
1mg71,00€2mg92,00€5mg152,00€10mg236,00€25mg380,00€50mg530,00€100mg708,00€1mL*10mM (DMSO)212,00€Ro5-3335
CAS:Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.Formula:C13H10ClN3OPurezza:99.42% - 99.87%Colore e forma:SolidPeso molecolare:259.69
