Ciclo cellulare/Checkpoint
Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.
Sottocategorie di "Ciclo cellulare/Checkpoint"
- Chinasi aurora(114 prodotti)
- CDK(544 prodotti)
- Arresto del ciclo cellulare(5 prodotti)
- Chk(47 prodotti)
- DYRK(47 prodotti)
- Dynamin(27 prodotti)
- Ferroptosi(226 prodotti)
- HSP(179 prodotti)
- Integrina(230 prodotti)
- Chinesina(87 prodotti)
- LIM chinasi(20 prodotti)
- Microtubulo associato(273 prodotti)
- PKC(120 prodotti)
- PLK(25 prodotti)
- ROCK(63 prodotti)
- Rho(6 prodotti)
- Wee1(14 prodotti)
- c-Myc(76 prodotti)
Mostrare 10 più sottocategorie
Trovati 3832 prodotti di "Ciclo cellulare/Checkpoint"
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Madrasin
CAS:Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.Formula:C16H17N5O2Purezza:99.06% - 99.61%Colore e forma:SolidPeso molecolare:311.34Dimethylenastron
CAS:Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.Formula:C16H18N2O2SPurezza:98.07%Colore e forma:SolidPeso molecolare:302.39Ref: TM-T3118
1mg34,00€2mg46,00€5mg58,00€10mg93,00€25mg147,00€50mg222,00€100mg334,00€1mL*10mM (DMSO)64,00€SCH900776 (S-isomer)
CAS:SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM).Formula:C15H18BrN7Purezza:99.88%Colore e forma:SolidPeso molecolare:376.25Ref: TM-T3700
1mg49,00€2mg70,00€5mg96,00€10mg155,00€25mg264,00€50mg424,00€100mg627,00€1mL*10mM (DMSO)114,00€THZ531
CAS:THZ531 is a covalent inhibitor of both CDK12(IC50=158 nM) and CDK13(IC50=69 nM).Formula:C30H32ClN7O2Purezza:97.17% - 99.86%Colore e forma:SolidPeso molecolare:558.07Ref: TM-T4293
1mg59,00€2mg86,00€5mg105,00€10mg144,00€25mg313,00€50mg447,00€100mg650,00€500mg1.341,00€1mL*10mM (DMSO)130,00€RAD51-IN-1
CAS:Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.Formula:C22H16ClN3OPurezza:99.95%Colore e forma:SolidPeso molecolare:373.83CBFβ Inhibitor
CAS:CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.Formula:C12H14N2OSPurezza:96.50%Colore e forma:SolidPeso molecolare:234.32NITD-2
CAS:NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Formula:C23H19N3O4SPurezza:98.03% - 99.46%Colore e forma:SolidPeso molecolare:433.48Ref: TM-T8886
1mg74,00€5mg170,00€10mg274,00€25mg472,00€50mg655,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)188,00€Monastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formula:C14H16N2O3SPurezza:98.02% - 98.59%Colore e forma:SolidPeso molecolare:292.35Ref: TM-T4048
1mg46,00€5mg73,00€10mg92,00€25mg178,00€50mg295,00€100mg477,00€500mg1.018,00€1mL*10mM (DMSO)93,00€AUZ 454
CAS:AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 50/18.6/15.4/9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.Formula:C24H26F3N7O2Purezza:99.59%Colore e forma:SolidPeso molecolare:501.5CX-5461
CAS:CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.Formula:C27H27N7O2SPurezza:95.44% - 99.4%Colore e forma:SolidPeso molecolare:513.61BVDV-IN-1
CAS:BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.Formula:C20H22N4OPurezza:98.43%Colore e forma:SolidPeso molecolare:334.41Ref: TM-T9103
1mg38,00€5mg86,00€10mg124,00€25mg241,00€50mg355,00€100mg507,00€200mg687,00€1mL*10mM (DMSO)95,00€PND-1186
CAS:PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formula:C25H26F3N5O3Purezza:99.14% - 99.75%Colore e forma:SolidPeso molecolare:501.5OSU-T315
CAS:OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Formula:C30H30F3N5OPurezza:98.69%Colore e forma:SolidPeso molecolare:533.59Ref: TM-T5485
1mg88,00€5mg187,00€10mg298,00€25mg533,00€50mg755,00€100mg1.008,00€200mg1.359,00€1mL*10mM (DMSO)220,00€HMN-176
CAS:HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1).Formula:C20H18N2O4SPurezza:98.92% - 98.99%Colore e forma:SolidPeso molecolare:382.43Ref: TM-T3643
1mg40,00€2mg52,00€5mg84,00€10mg113,00€25mg178,00€50mg333,00€100mg495,00€500mg1.071,00€1mL*10mM (DMSO)74,00€PHA-680632
CAS:PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively.Formula:C28H35N7O2Purezza:98.2%Colore e forma:SolidPeso molecolare:501.62Purvalanol B
CAS:Purvalanol B (NG 95) is a CDK inhibitor that inhibits Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p35, and Cdk2/cyclin B (IC50s = 6, 9, 6, and 6 nM, respectively)Formula:C20H25ClN6O3Purezza:98.95%Colore e forma:SolidPeso molecolare:432.9Ref: TM-T7167
1mg34,00€2mg46,00€5mg67,00€10mg90,00€25mg130,00€50mg203,00€100mg305,00€200mg447,00€1mL*10mM (DMSO)75,00€ARQ 621
CAS:ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.Formula:C28H24Cl2FN5O2Purezza:97.01% - 98.38%Colore e forma:SolidPeso molecolare:552.43Palbociclib monohydrochloride
CAS:Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinases
Formula:C24H29N7O2·HClPurezza:99.73% - >99.99%Colore e forma:SolidPeso molecolare:483.99Nolatrexed
CAS:Nolatrexed is a thymidylate synthase inhibitor with potential anticancer activity.Formula:C14H12N4OSPurezza:97.53%Colore e forma:SolidPeso molecolare:284.34Ref: TM-T4228
1mg39,00€2mg52,00€5mg86,00€10mg140,00€25mg226,00€50mg408,00€100mg600,00€1mL*10mM (DMSO)90,00€Rac1 Inhibitor W56 acetate(1095179-01-3 free base)
Rac1 Inhibitor W56 acetate(1095179-01-3 free base) is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activationFormula:C76H121N19O25SPurezza:98.96%Colore e forma:SolidPeso molecolare:1732.95
