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Ciclo cellulare/Checkpoint

Ciclo cellulare/Checkpoint

Gli inibitori del ciclo cellulare/dei checkpoint sono composti che interrompono la normale progressione del ciclo cellulare, in particolare nei principali punti di controllo regolatori. Questi inibitori sono fondamentali per studiare la divisione cellulare, comprendere la proliferazione delle cellule cancerose e sviluppare terapie antitumorali. Mirando a fasi specifiche del ciclo cellulare, questi inibitori possono indurre l'arresto del ciclo cellulare, portando all'apoptosi o alla senescenza nelle cellule che si dividono rapidamente. Presso CymitQuimica, offriamo una vasta gamma di inibitori di alta qualità del ciclo cellulare/dei checkpoint per supportare le tue ricerche in biologia del cancro, biologia cellulare e sviluppo di farmaci.

Sottocategorie di "Ciclo cellulare/Checkpoint"

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Trovati 3739 prodotti di "Ciclo cellulare/Checkpoint"

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  • Fradafiban
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    Fradafiban

    CAS:
    Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.
    Formula:C20H21N3O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:367.40

    Ref: TM-T11322

  • 3'-NH2-CTP
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    3'-NH2-CTP

    CAS:
    3'-NH2-CTP is a nucleotide analog modified with an amino group at the 3' position of CTP.
    Formula:C9H17N4O13P3
    Colore e forma:Solid
    Peso molecolare:482.17

    Ref: TM-TSW-01109

  • 12(S)-HETE
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    12(S)-HETE

    CAS:
    <p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>
    Formula:C20H32O3
    Colore e forma:Solid
    Peso molecolare:320.47

    Ref: TM-T37047

  • (R)-CSN5i-3
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    (R)-CSN5i-3

    CAS:
    (R)-CSN5i-3 is CSN5i-3 of the R configuration.
    Formula:C28H29F2N5O2
    Purezza:99.76% - 99.97%
    Colore e forma:Solid
    Peso molecolare:505.56

    Ref: TM-T12620

  • Eprociclovir Na
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    Eprociclovir Na

    CAS:
    Eprociclovir Na (A-5021) is 15x stronger than acyclovir at inhibiting herpesviruses, showing promise for EHV1 and herpetic keratitis treatment.
    Formula:C11H14N5NaO3
    Colore e forma:Solid
    Peso molecolare:287.25

    Ref: TM-T69817

  • Logo CymitQuimica
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    Anticancer agent 29

    <p>Compound E/Z-6f, anticancer, IC50: CDK2 (0.054 μM), CDK1 (0.127 μM), CDK4 (0.129 μM), CDK6 (0.396 μM).</p>
    Formula:C22H15ClFNO
    Colore e forma:Solid
    Peso molecolare:363.81

    Ref: TM-T61378

  • Logo CymitQuimica
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    Dyrk1A/α-synuclein-IN-2

    Dyrk1A/α-synuclein-IN-2 (Compound b20) is a dual inhibitor of Dyrk1A and α-synuclein aggregation that acts on α-synuclein (IC50: 7.8 μM).
    Formula:C21H16N4O4S
    Colore e forma:Solid
    Peso molecolare:420.44

    Ref: TM-T62226

  • LNA-CTP
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    LNA-CTP

    CAS:
    <p>LNA-CTP is a nucleotide analog utilized in the synthesis of oligonucleotides.</p>
    Formula:C10H16N3O14P3
    Colore e forma:Solid
    Peso molecolare:495.17

    Ref: TM-TSW-00954

  • IXA62
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    IXA62

    CAS:
    IXA62 is an orally active, selective IRE1/XBP1s agonist (EC50= 0.31 μM) that can reduce Aβ secretion.
    Formula:C24H23N3O3
    Colore e forma:Solid
    Peso molecolare:401.458

    Ref: TM-T206732

  • DHX9-IN-19
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    DHX9-IN-19

    CAS:
    <p>DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.</p>
    Formula:C20H21ClN4O4S2
    Colore e forma:Solid
    Peso molecolare:480.988

    Ref: TM-T204732

  • L 734217
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    L 734217

    CAS:
    L 734217 is an antagonist of the fibrinogen receptor.
    Formula:C18H31N3O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:353.46

    Ref: TM-T24352

  • Dyrk1A-IN-4
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    Dyrk1A-IN-4

    CAS:
    Dyrk1A-IN-4, compound 48, is an oral DYRK1A/DYRK2 inhibitor with IC50s: 2 nM (DYRK1A), 6 nM (DYRK2), anticancer properties.
    Formula:C14H13F3N6
    Colore e forma:Solid
    Peso molecolare:322.29

    Ref: TM-T60867

  • Cdc7-IN-19
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    Cdc7-IN-19

    CAS:
    Cdc7-IN-19 (compound 1-1) is a potent CDC7 inhibitor with an IC 50 of 1.49 nM [1].
    Formula:C19H21N5O2
    Colore e forma:Solid
    Peso molecolare:351.40

    Ref: TM-T61223

  • Cdc7-IN-18
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    Cdc7-IN-18

    CAS:
    <p>Cdc7-IN-18 (1-2) inhibits CDC7 enzyme (IC50: 1.29 nM) and COLO205 cell proliferation (IC50: 53.62 nM).</p>
    Formula:C19H21N5OS
    Colore e forma:Solid
    Peso molecolare:367.47

    Ref: TM-T61436

  • GR 83895
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    GR 83895

    CAS:
    GR 83895 is an antagonist of prototype fibrinogen receptor.
    Formula:C29H39N9O8S
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:673.74

    Ref: TM-T25460

  • Polθ-IN-7
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    Polθ-IN-7

    CAS:
    <p>Polθ-IN-7 (example 12) is an inhibitor of DNA polymerase θ (Polθ) with a Ki of 1.27 nM.</p>
    Formula:C28H35F3N6O2
    Colore e forma:Solid
    Peso molecolare:544.612

    Ref: TM-T204135

  • 3'-Deoxy-GTP
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    3'-Deoxy-GTP

    CAS:
    <p>3'-Deoxy-GTP (3′-Deoxyguanosine 5′-triphosphate) is an analog of GTP and serves as an RNA chain terminator, effectively inhibiting RNA synthesis. It can inhibit dengue virus DENV NS5 RdRp with an IC50 of 0.02 μM.</p>
    Formula:C10H16N5O13P3
    Colore e forma:Solid
    Peso molecolare:507.181

    Ref: TM-T206927

  • ROCK-IN-11
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    ROCK-IN-11

    CAS:
    ROCK-IN-11 (example 94) is an effective inhibitor of ROCK1 and ROCK2, with an IC50 of ≤ 5 μM, and plays a significant role in cancer research.
    Formula:C22H20N4O4S
    Colore e forma:Solid
    Peso molecolare:436.484

    Ref: TM-T204468

  • isoGTP lithium
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    isoGTP lithium

    CAS:
    isoGTP (Isoguanosine-5'-triphosphate) lithium is a GTP analog.
    Formula:C10H12Li4N5O14P3
    Colore e forma:Solid
    Peso molecolare:546.91

    Ref: TM-T212259

  • CDK8-IN-14
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    CDK8-IN-14

    CAS:
    <p>CDK8-IN-14 (compound 12) effectively inhibits CDK8, demonstrating an IC50 of 39.2 nM, and exhibits potent anti-AML cell proliferation effects, with a GC50 value of 0.02±0.01μM in MOLM-13 cells and 0.03±0.01μM in MV4-11 cells [1].</p>
    Formula:C18H13N3O2
    Colore e forma:Solid
    Peso molecolare:303.31

    Ref: TM-T86031