Adattatori Tirosin-chinasi
Gli inibitori delle tirosine chinasi e degli adattatori sono composti che bersagliano le tirosine chinasi e le loro proteine adattatrici associate, che svolgono ruoli cruciali nella segnalazione cellulare, nella crescita e nella differenziazione. Questi inibitori sono strumenti essenziali nella ricerca sul cancro, poiché molte tirosine chinasi sono coinvolte nelle vie di segnalazione che promuovono la crescita e la metastasi tumorale. Inibendo le tirosine chinasi, questi composti possono bloccare cascate di segnalazione critiche, offrendo potenziali strategie terapeutiche per vari tipi di cancro e altre malattie che coinvolgono una segnalazione cellulare anomala. Presso CymitQuimica, offriamo una vasta gamma di inibitori di tirosine chinasi e adattatori di alta qualità per supportare la tua ricerca in oncologia, biologia molecolare e sviluppo di terapie mirate.
Sottocategorie di "Adattatori Tirosin-chinasi"
- ALK(129 prodotti)
- CSF-1R(42 prodotti)
- EGFR(591 prodotti)
- Recettore di Ephrin(25 prodotti)
- FLT(91 prodotti)
- Recettore del fattore di crescita dei fibroblasti (FGFR)(183 prodotti)
- HER(3 prodotti)
- Hck(3 prodotti)
- IGF-1R(104 prodotti)
- PDGFR(128 prodotti)
- PYK2(7 prodotti)
- Src(81 prodotti)
- Ricettore TAM(33 prodotti)
- Tie-2(20 prodotti)
- Recettore Trk(57 prodotti)
- Tirosin-chinasi(25 prodotti)
- VEGFR(246 prodotti)
- c-Fms(112 prodotti)
- c-Kit(115 prodotti)
- c-Met/HGFR(139 prodotti)
- c-RET(62 prodotti)
Mostrare 13 più sottocategorie
Trovati 1167 prodotti di "Adattatori Tirosin-chinasi"
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NVP-BHG 712
CAS:Formula:C26H20F3N7OPurezza:>95.0%(HPLC)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:503.49Tyrphostin AG 490
CAS:Formula:C17H14N2O3Purezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:294.31Lapatinib
CAS:Formula:C29H26ClFN4O4SPurezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:581.06Sorafenib
CAS:Formula:C21H16ClF3N4O3Purezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:464.83Tyrphostin A1
CAS:Formula:C11H8N2OPurezza:>98.0%(GC)Colore e forma:Light orange to Yellow to Green powder to crystalPeso molecolare:184.20Gefitinib
CAS:Formula:C22H24ClFN4O3Purezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:446.91Tyrphostin AG 835
CAS:Formula:C18H16N2O3Purezza:>98.0%(HPLC)Colore e forma:Light yellow to Amber to Dark green powder to crystalPeso molecolare:308.34Imatinib
CAS:Formula:C29H31N7OPurezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:493.62Piceatannol
CAS:Formula:C14H12O4Purezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light red powder to crystalPeso molecolare:244.25Tyrphostin AG528
CAS:Formula:C18H14N2O3Purezza:>97.0%(HPLC)Colore e forma:Light yellow to Amber to Dark green powder to crystalPeso molecolare:306.32TCS 359
CAS:Formula:C18H20N2O4SPurezza:>98.0%(HPLC)Colore e forma:Light yellow to Brown powder to crystalPeso molecolare:360.43Tyrphostin AG 494
CAS:Formula:C16H12N2O3Purezza:>98.0%(HPLC)(N)Colore e forma:Light yellow to Amber to Dark green powder to crystalPeso molecolare:280.28Curcumin (Synthetic)
CAS:Formula:C21H20O6Purezza:>97.0%(T)Colore e forma:Light yellow to Brown powder to crystalPeso molecolare:368.39Curcumin (Natural)
CAS:Formula:C21H20O6Colore e forma:Light yellow to Brown powder to crystalPeso molecolare:368.39Axitinib
CAS:Formula:C22H18N4OSPurezza:>95.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:386.47Erlotinib Hydrochloride
CAS:Formula:C22H23N3O4·HClPurezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:429.90PD 153035 Hydrochloride
CAS:Formula:C16H14BrN3O2·HClPurezza:>97.0%(HPLC)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:396.67SB 431542
CAS:Formula:C22H16N4O3Purezza:>97.0%(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:384.40Dasatinib
CAS:Formula:C22H26ClN7O2SPurezza:>95.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:488.01SKLB1002
CAS:Formula:C13H12N4O2S2Purezza:>98.0%(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:320.39GW 2580
CAS:Formula:C20H22N4O3Purezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:366.42Butein
CAS:Formula:C15H12O5Purezza:>98.0%(HPLC)Colore e forma:Light yellow to Brown powder to crystalPeso molecolare:272.26LFM-A13
CAS:Formula:C11H8Br2N2O2Purezza:>98.0%(HPLC)Colore e forma:Light yellow to Brown powder to crystalPeso molecolare:360.01Afatinib
CAS:Formula:C24H25ClFN5O3Purezza:>97.0%(HPLC)(N)Colore e forma:White to Orange to Green powder to crystalPeso molecolare:485.94Genistein
CAS:Formula:C15H10O5Purezza:>98.0%(HPLC)Colore e forma:White to Light yellow to Light orange powder to crystalPeso molecolare:270.24Methyl 2,5-Dihydroxycinnamate
CAS:Formula:C10H10O4Purezza:>96.0%(HPLC)Colore e forma:White to Yellow powder to crystalPeso molecolare:194.19Tyrphostin A23
CAS:Formula:C10H6N2O2Purezza:>98.0%(GC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:186.17Sorafenib Tosylate
CAS:Formula:C21H16ClF3N4O3·C7H8O3SPurezza:>98.0%(T)(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:637.03Pelitinib
CAS:Formula:C24H23ClFN5O2Purezza:>97.0%(HPLC)Colore e forma:White to Light yellow powder to crystalPeso molecolare:467.93RPI 1
CAS:Formula:C17H15NO4Purezza:>95.0%(HPLC)Colore e forma:Light yellow to Brown powder to crystalPeso molecolare:297.31Delgocitinib
CAS:Delgocitinib is a potent JAK inhibitor (IC50: 2.8-58 nM), treats inflammatory diseases, and is the first topical drug for atopic dermatitis.Formula:C16H18N6OPurezza:99.95%Colore e forma:SolidPeso molecolare:310.35Ref: TM-T15096
1mg169,00€5mg311,00€10mg487,00€25mg929,00€50mg1.415,00€100mg2.062,00€200mg2.775,00€1mL*10mM (DMSO)349,00€Erlotinib hydrochloride
CAS:<p>Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Formula:C22H23N3O4·HClPurezza:99.78% - 99.85%Colore e forma:White Or Off-White PowderPeso molecolare:429.9Ilginatinib maleate
CAS:<p>Ilginatinib maleate (NS-018 maleate) is a highly active and orally bioavailable inhibitor of JAK2.</p>Formula:C25H24FN7O4Purezza:99.74% - 99.82%Colore e forma:SolidPeso molecolare:505.5Khellin
CAS:Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.Formula:C14H12O5Purezza:99.89% - 99.95%Colore e forma:Light Yellow CrystallinePeso molecolare:260.24Epertinib hydrochloride
CAS:Epertinib hydrochloride (S-22611 hydrochloride) shows potent antitumor activity.Formula:C30H28Cl2FN5O3Purezza:99.14%Colore e forma:SolidPeso molecolare:596.48Ref: TM-T11213
1mg92,00€5mg188,00€10mg311,00€25mg533,00€50mg755,00€100mg1.017,00€500mg2.043,00€1mL*10mM (DMSO)255,00€1-[4-[4-[[2-[(1E)-2-[4-(Trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole
CAS:Formula:C25H23F3N4O2Purezza:98%Colore e forma:SolidPeso molecolare:468.4709Intetumumab
CAS:Intetumumab (CNTO 95) is a fully humanized anti-α(v)-integrin monoclonal antibody that is a radiosensitizer for xenograft tumor-bearing mice.Purezza:97.6% (SDS-PAGE); 97.1% (SEC-HPLC) - 97.6% (SDS-PAGE); 97.1% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:145.6 (kDa)1,3-Benzodioxole, 5-(2-nitroethenyl)-
CAS:Formula:C9H7NO4Purezza:98%Colore e forma:SolidPeso molecolare:193.15624-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
CAS:Formula:C22H16N4O3Purezza:97%Colore e forma:SolidPeso molecolare:384.38744H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-
CAS:Formula:C15H10O5Purezza:97%Colore e forma:SolidPeso molecolare:270.2369Ref: IN-DA00I8G3
1g26,00€5g24,00€10g31,00€1kg686,00€25g52,00€50g77,00€5kgPrezzo su richiesta100g114,00€10kgPrezzo su richiesta250g181,00€500g320,00€100mg26,00€AV-412
CAS:AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).Formula:C41H44ClFN6O7S2Purezza:99.85% - 99.92%Colore e forma:SolidPeso molecolare:851.41Ref: TM-T10419
1mg44,00€2mg58,00€5mg95,00€10mg144,00€25mg254,00€50mg424,00€100mg613,00€1mL*10mM (DMSO)136,00€Emibetuzumab
CAS:Emibetuzumab: potent humanized MET antibody, antitumor, inhibits HGF/MET pathways, for advanced prostate cancer research.Purezza:SDS-PAGE:96.2%;SEC-HPLC:98.8%Colore e forma:LiquidPeso molecolare:143.74 kDaBarecetamab
CAS:Barecetamab (ISU-104) is a humanized monoclonal antibody against tyrosine protein kinase ErbB3 with anticancer activity.Purezza:97.1% (SDS-PAGE); 96.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 96.4% (SEC-HPLC)Colore e forma:LiquidQuinoxaline, 6,7-dimethoxy-2-phenyl-
CAS:Formula:C16H14N2O2Purezza:98%Colore e forma:SolidPeso molecolare:266.2946Ref: IN-DA001E48
1gPrezzo su richiesta1mg53,00€5mg54,00€10mg73,00€25mg107,00€50mg164,00€100mg187,00€250mg503,00€2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride
CAS:Formula:C20H21N3O2Purezza:98%Colore e forma:SolidPeso molecolare:335.3996BLU-945
CAS:<p>BLU-945 is a reversible, potent, highly selective, and orally available epidermal growth factor receptor tyrosine kinase inhibitor (TKIs).Cost-effective and quality-assured.</p>Formula:C28H37FN6O3SPurezza:99.11% - 99.16%Colore e forma:SolidPeso molecolare:556.7Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Formula:C29H26ClFN4O4S·2C7H8O3SPurezza:99.41%Colore e forma:Yellow SolidPeso molecolare:925.462H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-
CAS:Formula:C15H14N2OPurezza:98%Colore e forma:SolidPeso molecolare:238.2845O-Desmethyl gefitinib
CAS:O-Desmethyl gefitinib is an active EGFR inhibitor (IC50: 36 nM), a metabolite of Gefitinib, formed by CYP2D6.Formula:C21H22ClFN4O3Purezza:97.17%Colore e forma:SolidPeso molecolare:432.88Ref: TM-T16369
1mg56,00€5mg111,00€10mg170,00€25mg343,00€50mg547,00€100mg783,00€1mL*10mM (DMSO)120,00€Ganitumab
CAS:Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used in cancer research.Purezza:100% (SEC-HPLC) - > 95%Colore e forma:LiquidPeso molecolare:145.70 kDaGancotamab
CAS:Gancotamab (MM-302) is a polyethylene glycolated liposome targeting HER2 with antitumor activity for the study of advanced HER2-positive breast cancer.Purezza:96.7% (SDS-PAGE); 98.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 98.4% (SEC-HPLC)Colore e forma:Liquid2-(3,4-Dimethoxyphenylcarbamoyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS:Formula:C18H20N2O4SPurezza:95%Colore e forma:SolidPeso molecolare:360.4274GIP (3-42), human
CAS:Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes research.Formula:C214H324N58O63SPurezza:95.73%Colore e forma:SolidPeso molecolare:4749.35CE-245677
CAS:<p>CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases. With a cellular IC50s of 4.7 and 1 nM.</p>Formula:C24H22Cl2N6O3Purezza:98.99% - 99.23%Colore e forma:SolidPeso molecolare:513.38Bozitinib
CAS:<p>Bozitinib (PLB-1001) (PLB-1001) is a highly selective inhibitor of the c-MET kinase with blood-brain barrier permeability.</p>Formula:C20H15F3N8Purezza:99.16%Colore e forma:SolidPeso molecolare:424.38Lapatinib
CAS:Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity.Formula:C29H26ClFN4O4SPurezza:99.00% - 99.81%Colore e forma:PowderPeso molecolare:581.06Lapatinib ditosylate monohydrate
CAS:<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Formula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPurezza:98% - 99.41%Colore e forma:Colourless To Light-Yellow CrystalPeso molecolare:943.47ARQ 531
CAS:<p>ARQ-531: potent oral BTK inhibitor, anti-cancer potential, IC50 of 0.85/0.39 nM for WT/C481S-BTK.</p>Formula:C25H23ClN4O4Purezza:98.68% - 99.63%Colore e forma:SolidPeso molecolare:478.93LCH-7749944
CAS:LCH-7749944 suppresses human gastric cancer cell growth, induces apoptosis, and inhibits PAK4 with IC50 of 14.93 μM.Formula:C20H22N4O2Purezza:99.48%Colore e forma:SolidPeso molecolare:350.41Ref: TM-T11826
1mg49,00€5mg108,00€10mg164,00€25mg284,00€50mg424,00€100mg615,00€200mg830,00€1mL*10mM (DMSO)116,00€Erlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Formula:C22H23N3O4Purezza:98.19% - 99.98%Colore e forma:White To Off-White PowderPeso molecolare:393.44Ref: IN-DA003MZ1
1gPrezzo su richiesta5gPrezzo su richiesta10gPrezzo su richiesta1mg47,00€25gPrezzo su richiesta5mg53,00€10mg63,00€50mg171,00€100mg207,00€250mg548,00€2-Butenamide, 2-cyano-N-(2,5-dibromophenyl)-3-hydroxy-
CAS:Formula:C11H8Br2N2O2Purezza:98%Colore e forma:SolidPeso molecolare:360.0014Ref: IN-DA00EB3N
5mg133,00€10mg167,00€25mg294,00€50mg349,00€100mgPrezzo su richiesta250mgPrezzo su richiesta(2E)-N-(4-{[3-chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
CAS:Formula:C30H29ClN6O3Purezza:98%Colore e forma:SolidPeso molecolare:557.0427Ref: IN-DA0035DM
1g152,00€5g491,00€nePrezzo su richiesta5mg28,00€25mg49,00€50mg58,00€100mg71,00€250mg78,00€1,2-Benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-
CAS:Formula:C14H12O4Purezza:97%Colore e forma:SolidPeso molecolare:244.24274-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-, hydrochloride (1:1)
CAS:Formula:C22H23ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:429.8967(E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
CAS:Formula:C17H14N2O3Purezza:98%Colore e forma:SolidPeso molecolare:294.30474-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
CAS:Formula:C21H16ClF3N4O3Purezza:99%Colore e forma:SolidPeso molecolare:464.8249Bucladesine sodium
CAS:Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties.Formula:C18H23N5NaO8PPurezza:96.56% - 99.76%Colore e forma:White PowderPeso molecolare:491.37CSF1R-IN-2
CAS:CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).Formula:C20H20FN7O2Purezza:99.29%Colore e forma:SolidPeso molecolare:409.424-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide
CAS:Formula:C29H31N7OPurezza:98%Colore e forma:SolidPeso molecolare:493.6027Ref: IN-DA00350H
1g25,00€5g33,00€10g56,00€1kg506,00€25g61,00€5kgPrezzo su richiesta100g164,00€10kgPrezzo su richiesta500g687,00€N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine
CAS:Formula:C22H24ClFN4O3Purezza:98%Colore e forma:SolidPeso molecolare:446.9024GIP (human) acetate
GIP (human) acetate boosts insulin, limits gastric acid, affects lipid metabolism, and obesity development.Purezza:98.65%Colore e forma:SoildOrelabrutinib
CAS:<p>Orelabrutinib (ICP-022) is an orally active and irreversible inhibitor of Bruton's tyrosine kinase (BTK).</p>Formula:C26H25N3O3Purezza:97.77% - 99.54%Colore e forma:SolidPeso molecolare:427.49AZ7550 hydrochloride
CAS:AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Formula:C27H32ClN7O2Purezza:99.65%Colore e forma:SolidPeso molecolare:522.04Mutated EGFR-IN-1
CAS:Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activatingFormula:C25H31N7OPurezza:98.91%Colore e forma:SolidPeso molecolare:445.56GSK-626616
CAS:GSK-626616: strong, oral DYRK3 inhibitor (IC50: 0.7 nM), affects DYRK family, may treat anemia.Formula:C18H10Cl2N4OSPurezza:98.27%Colore e forma:SolidPeso molecolare:401.27SU 5616
CAS:<p>SU 5616 (WAY-608241) regulates abnormal cell proliferation and modulates tyrosine kinase signaling.</p>Formula:C13H8ClNOSPurezza:98.84%Colore e forma:SoildPeso molecolare:261.73(2E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]-2-propenamide
CAS:Formula:C18H16N2O3Purezza:97%Colore e forma:SolidPeso molecolare:308.3312Propanedinitrile,2-[(4-methoxyphenyl)methylene]-
CAS:Formula:C11H8N2OPurezza:98%Colore e forma:SolidPeso molecolare:184.1940(2E)-2-Cyano-3-(3,5-di-tert-butyl-4-hydroxyphenyl)prop-2-enethioamide
CAS:Formula:C18H24N2OSPurezza:95%Colore e forma:SolidPeso molecolare:316.4610Ilginatinib
CAS:Ilginatinib (NS-018) is a highly active and orally bioavailable inhibitor of JAK2.Formula:C21H20FN7Purezza:98.4% - 99.01%Colore e forma:SolidPeso molecolare:389.43Ref: TM-T12266
1mg64,00€5mg138,00€10mg187,00€25mg273,00€50mg393,00€100mg562,00€200mg743,00€1mL*10mM (DMSO)133,00€N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine
CAS:Formula:C29H26ClFN4O4SPurezza:98%Colore e forma:SolidPeso molecolare:581.0575Ref: IN-DA0039KT
1g106,00€5g222,00€50g573,00€100gPrezzo su richiesta250gPrezzo su richiesta25mg29,00€100mg44,00€250mg56,00€2H-1-Benzopyran-2-one, 7,8-dihydroxy-
CAS:Formula:C9H6O4Purezza:95%Colore e forma:SolidPeso molecolare:178.1415(E)-2-Cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide
CAS:Formula:C25H30N2O2Purezza:98%Colore e forma:SolidPeso molecolare:390.5179Methyl 2,5-Dihydroxycinnamate
CAS:Formula:C10H10O4Purezza:95%Colore e forma:SolidPeso molecolare:194.1840Rociletinib
CAS:<p>Rociletinib (CNX-419) is an orally available small molecule, irreversible inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic</p>Formula:C27H28F3N7O3Purezza:98.52% - 99.25%Colore e forma:SolidPeso molecolare:555.554-Quinazolinamine, N-(3-chlorophenyl)-6,7-dimethoxy-
CAS:Formula:C16H14ClN3O2Purezza:99%Colore e forma:SolidPeso molecolare:315.7543TAM-IN-2
CAS:TAM-IN-2 is an inhibitor of TAM.Formula:C31H27F2N7O3Purezza:98.09% - 99.74%Colore e forma:SolidPeso molecolare:583.59Bosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formula:C26H29Cl2N5O3Purezza:98.98% - 99.9%Colore e forma:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecolare:530.45Panitumumab
CAS:Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).Purezza:95% - 98.1% (SDS-PAGE); 99.4% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:147 kDaGunagratinib
CAS:Gunagratinib (ICP-192) is a pan-FGFR inhibitor, useful in research on FGFR-related diseases.Formula:C22H25N5O4Purezza:99.68%Colore e forma:SolidPeso molecolare:423.47Ref: TM-T39682
1mg72,00€5mg156,00€10mg235,00€25mg378,00€50mg540,00€100mg747,00€1mL*10mM (DMSO)167,00€c-Met inhibitor 1
CAS:c-Met inhibitor 1 is a c-Met receptor signaling pathway inhibitor, used for the treatment of cancer including glioblastoma, gastric, and pancreatic cancer.Formula:C17H14N8SPurezza:98.77%Colore e forma:SolidPeso molecolare:362.41Ref: IN-DA00AP0L
1gPrezzo su richiesta1mg27,00€5mg67,00€10mg81,00€25mg110,00€50mg126,00€100mg193,00€250mg273,00€Tilvestamab
CAS:Tilvestamab (BGB149) is a humanized monoclonal antibody targeting AXL with anti-tumor and anti-fibrotic activities, inhibiting Gas6-induced AXL activation.Purezza:>95%Colore e forma:LiquidHck-IN-1
CAS:Hck-IN-1 selectively inhibits Nef:Hck, IC50: 2.8 μM; >20 μM for Hck alone. Potent HIV-1 Nef antagonist, IC50: 100-300 nM for HIV-1 replication.Formula:C16H11ClN6O3SPurezza:99.07%Colore e forma:SolidPeso molecolare:402.81Ref: TM-T11538
1mg97,00€5mg216,00€10mg344,00€25mg567,00€50mg825,00€100mg1.121,00€200mg1.510,00€1mL*10mM (DMSO)240,00€Ref: IN-DA01DU9U
2mg112,00€5mg161,00€10mg156,00€25mg310,00€50mg701,00€100mgPrezzo su richiesta250mgPrezzo su richiestaPetosemtamab
CAS:<p>Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR & LGR5, used in solid tumor research like HNSCC & CRC.</p>Purezza:> 95% - > 95%Colore e forma:LiquidPeso molecolare:145.97 kDaPyrotinib dimaleate
CAS:Pyrotinib dimaleate is a selective EGFR/HER2 dual inhibitor, respectively, for the treatment of HER2-positive breast cancer.Cost-effective and quality-assured.Formula:C40H39ClN6O11Purezza:97.27% - 99.52%Colore e forma:SolidPeso molecolare:815.22Ref: TM-T12594
1mg155,00€5mg457,00€10mg610,00€25mg947,00€50mg1.301,00€100mg1.758,00€1mL*10mM (DMSO)620,00€Lacnotuzumab
CAS:Lacnotuzumab (MCS110) is a humanized monoclonal antibody targeting CSF-1, which can be used in research on retinal diseases.Purezza:>95%Colore e forma:LiquidCEP-28122 mesylate salt (1022958-60-6 free base)
CEP-28122 mesylate salt (1022958-60-6 free base) is a highly selective orally active ALK inhibitor (IC50: 1.9 nM in an enzyme-based TRF assay).Formula:C29H39ClN6O6SPurezza:99.79%Colore e forma:SolidPeso molecolare:635.17Rilotumumab
CAS:<p>Rilotumumab (AMG 102) is an HGF-targeting antibody, inhibits HGF/MET signaling, and is used for CRPC and gastric cancer research.</p>Purezza:SDS-PAGE:95% SEC-HPLC:97.51%Colore e forma:LiquidPeso molecolare:145.2 kDaIBT6A
CAS:<p>IBT6A is an impurity of Ibrutinib. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM). IBT6A can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct.</p>Formula:C22H22N6OPurezza:99.8% - 99.88%Colore e forma:SolidPeso molecolare:386.452-ButynaMide, N-[4-[(3-broMophenyl)aMino]-6-quinazolinyl]-
CAS:Formula:C18H13BrN4OPurezza:97%Colore e forma:SolidPeso molecolare:381.2260Ref: IN-DA00ABJJ
2mg51,00€5mg79,00€10mg119,00€25mg186,00€50mg225,00€100mg506,00€500mgPrezzo su richiestaAllitinib
CAS:Allitinib (AST-1306) (AST-1306) has anti-cancer activity，and it is an irreversible EGFR and ErbB2 inhibitor with IC50s of 0.5 and 3 nM, respectively. [1]Formula:C24H18ClFN4O2Purezza:99.89% - 99.91%Colore e forma:SolidPeso molecolare:448.88Ref: TM-T14336
1mg52,00€5mg111,00€10mg175,00€25mg329,00€50mg494,00€100mg700,00€1mL*10mM (DMSO)135,00€AZ-Dyrk1B-33
CAS:AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.Formula:C19H16N4Purezza:99.91%Colore e forma:SolidPeso molecolare:300.36Ref: TM-T14364
1mg47,00€5mg97,00€10mg156,00€25mg304,00€50mg442,00€100mg615,00€200mg832,00€1mL*10mM (DMSO)105,00€Emactuzumab
CAS:<p>Emactuzumab(RG 7155) is a monoclonal antibody against colony-stimulating factor-1 receptor targeting tumor-associated macrophages (TAMs) Emactuzumab has</p>Purezza:SDS-PAGE:98.3%;SEC-HPLC:97.3%Colore e forma:LiquidPeso molecolare:144.4 kDaTirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C27H33N3O6SPurezza:99%Colore e forma:SolidPeso molecolare:527.63Ref: TM-T15675
2mg38,00€5mg56,00€10mg70,00€25mg126,00€50mg243,00€100mg416,00€200mg562,00€1mL*10mM (DMSO)65,00€JNJ-38877618
CAS:JNJ-38877618 (OMO-1) is an effective and highly selective inhibitor of Met kinase (IC50s: 2 and 3 nM for wild type and mutant Met, respectively).Formula:C20H12F2N6Purezza:98.84% - 99.74%Colore e forma:SolidPeso molecolare:374.35Ref: TM-T15617
1mg63,00€5mg137,00€10mg210,00€25mg424,00€50mg620,00€100mg817,00€200mg1.103,00€1mL*10mM (DMSO)153,00€Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Formula:C9H11NO3·HClPurezza:99.94%Colore e forma:SolidPeso molecolare:217.65CSF1R-IN-1
CAS:CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.Formula:C25H20F3N5O2Purezza:97.02% - 98.56%Colore e forma:SolidPeso molecolare:479.45Ref: TM-T10894
1mg94,00€5mg210,00€10mg325,00€25mg550,00€50mg787,00€100mg1.093,00€200mg1.454,00€1mL*10mM (DMSO)230,00€Gefitinib
CAS:Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations.Formula:C22H24ClFN4O3Purezza:99.92% - >99.99%Colore e forma:Light-Yellow Crystalline PowderPeso molecolare:446.9Mevastatin
CAS:Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Formula:C23H34O5Purezza:99.12%Colore e forma:White-Yellowish To Yellow Powder Solid PowderPeso molecolare:390.51Losatuxizumab
CAS:Losatuxizumab (ABT-806) is an anti-EGFR monoclonal antibody with potential anti-tumor activity for the study of advanced malignant solid tumors.Purezza:97.3% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.3% (SDS-PAGE); 95.1% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:144.85 kDaEdicotinib
CAS:<p>Edicotinib (JNJ-527) is a blood-brain permeable, selective CSF-1R inhibitor, with lesser inhibitory effects on KIT and FLT3.Cost-effective and quality-assured.</p>Formula:C27H35N5O2Purezza:98.58% - 99.72%Colore e forma:SolidPeso molecolare:461.6Axatilimab
CAS:Axatilimab (SNDX-6352) is a human IgG4 antibody that targets CSF-1R and can be used to study immune system diseases and respiratory diseases.Purezza:97.9% (SDS-PAGE); 97% (SEC-HPLC) - 97.9% (SDS-PAGE); 97% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:147.17 kDaRobatumumab
CAS:Robatumumab (Sch 717454) is a fully humanized anti-IGF-1R monoclonal antibody with antitumor activity and antiproliferative activity.Purezza:96.9% (SDS-PAGE); 98.1% (SEC-HPLC) - 96.9% (SDS-PAGE); 98.1% (SEC-HPLC)Colore e forma:LiquidHyT36
CAS:HyT36: hydrophobic tag that destabilizes fusion proteins & Her3 pseudokinase; treats cells with acute erht.Formula:C25H44ClNO3Purezza:99.02%Colore e forma:SolidPeso molecolare:442.07Ref: TM-T72075
1mg56,00€5mg119,00€10mg188,00€25mg393,00€50mg628,00€100mg908,00€1mL*10mM (DMSO)131,00€Dasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formula:C22H28ClN7O3SPurezza:99.68% - >99.99%Colore e forma:SolidPeso molecolare:506.03Dasatinib
CAS:<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Formula:C22H26ClN7O2SPurezza:99.59% - 99.86%Colore e forma:Pale-Yellow SolidPeso molecolare:488.01Onartuzumab
CAS:Onartuzumab (MetMAb) is a humanized monoclonal antibody targeting c-MET, with antitumor effects by blocking HGF and signal transduction.Purezza:97.3%Colore e forma:LiquidPeso molecolare:146.99 kDa2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
CAS:Formula:C21H15ClF4N4O3Purezza:98%Colore e forma:SolidPeso molecolare:482.8154Ref: IN-DA00ICN3
1g131,00€5g255,00€10g619,00€50g617,00€100gPrezzo su richiesta10mg30,00€50mg46,00€100mg56,00€250mg69,00€500mg100,00€Margetuximab
CAS:Margetuximab (MGAH-22) is a second generation anti-HER2 monoclonal antibody with anti-tumor activity.Purezza:95.3% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.3% (SDS-PAGE); 99.3% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:145.86 kDaEGFR-IN-124
EGFR-IN-124 (compound 10A) is an EGFR inhibitor with an IC50 value of 0.54 μM, utilized in cancer research.Colore e forma:Odour SolidHER2/neu (654-662) GP2 acetate
<p>GP2 acetate, from HER2 (654-662), triggers HLA-A2-restricted T cells to attack epithelial cancers.</p>Formula:C44H81N9O13Purezza:98%Colore e forma:SolidPeso molecolare:944.17Ref: TM-TP1583L
1mg185,00€5mg415,00€10mg622,00€25mg1.119,00€50mg1.679,00€100mg2.520,00€200mg3.780,00€EGFR-IN-127
EGFR-IN-127 is an ATP-competitive inhibitor targeting EGFR, with IC50 values of 136.3 nM for EGFRdel19 and 161.2 nM for EGFRdel19/T790M/C797S. This compound holds potential for the study of non-small cell lung cancer (NSCLC).Colore e forma:Odour SolidAck1 inhibitor 2
CAS:Ack1 Inhibitor 2, also referred to as Example 259, effectively inhibits Ack1 with an IC50 value of 0.46 μM [1].Formula:C23H23N5O2Colore e forma:SolidPeso molecolare:401.46STAD 2
CAS:STAD-2 is a cell permeable akap disruptor, selectively binding to pka-rii and blocking the interaction of pka-ri with akapFormula:C102H182N24O22Colore e forma:SolidPeso molecolare:2096.724PRMT5/EGFR-IN-1
PRMT5/EGFR-IN-1 (Compound 10p) is an orally active dual inhibitor targeting PRMT5 and EGFR, with IC50 values of 15.47 μM and 19.31 μM, respectively. It demonstrates antiproliferative activity against the A549, MCF7, HeLa, and MDA-MB-231 cell lines. This compound also exhibits favorable pharmacokinetic (PK) and pharmacodynamic (PD) properties in vivo and significantly inhibits the growth of MCF7 orthotopic xenograft tumors.Formula:C27H22F6N2O2Peso molecolare:520.15855pYEEI
<p>pYEEI, a tetrapeptide containing phosphotyrosine, binds to the SrcSH2 domain with a dissociation constant (Kd) of 100 nM and an inhibitory concentration (IC50) of 6.5 μM. This compound plays a crucial role in cancer research.</p>Formula:C25H36N3O14PColore e forma:SolidPeso molecolare:633.54H1-7 (histone H1 phosphorylation site), PKA Substrate
CAS:H1-7 (histone H1 phosphorylation site), a synthetic polypeptide serving as a PKA substrate, demonstrates utility in PKA substrate applications [1] [2].Formula:C31H58N14O9Colore e forma:SolidPeso molecolare:770.88DS06652923
DS06652923 is an orally active inhibitor targeting EGFR triple mutations. It exhibits growth-inhibitory effects on Ba/F3EGFRdel19/T90M/C795S cells, with a GI50 value of 9.4 nM. Additionally, DS06652923 induces tumor regression in the Ba/F3 syngeneic transplantation model.Colore e forma:Odour SolidHerceptide
CAS:Herceptide (HER2-targeting peptide), a peptide that targets HER2, can be conjugated with the near-infrared fluorescent dye indocyanine green (ICG), facilitating the development of theranostic agents.Formula:C76H110N22O23Colore e forma:SolidPeso molecolare:1699.82PROTAC EGFR degrader 10
CAS:PROTAC EGF Rdegrader 10 (Compound B56) is a PROTAC degrader targeting the epidermal growth factor receptor (EGFR) with a DC50 of less than 100 nM. It binds to CRBN-DDB1 with a Ki of 37 nM and degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibiting the proliferation of BaF3 wild-type and EGFR mutants with an IC50 of less than 150 nM.Formula:C49H65ClN10O7SColore e forma:SolidPeso molecolare:973.62EGFR/HER2-IN-15
EGFR/HER2-IN-15 is a dihydropyrimidine and an effective inhibitor of EGFR/HER2. It significantly suppresses EGFRwt activity with an IC50 of 37.21 nM and exhibits anticancer properties.Formula:C28H29N3O6Peso molecolare:503.20564Depatuxizumab MMAF
<p>Depatuxizumab-MMAF, an antibody-drug conjugate (ADC), comprises an EGFR-targeted antibody linked to McMMAF and is utilized in glioblastoma research.</p>Colore e forma:LiquidPeso molecolare:148.24 kDaPKI (5-24),amide
CAS:PKI (5-24),amide is a 20-residue peptide, a potent PKA inhibitor with a Ki of 2.3 nM, derived from a cAMP inhibitor protein.Formula:C94H149N33O30Colore e forma:SolidPeso molecolare:2221.4PROTAC EGFR degrader 11
CAS:<p>PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader targeting the epidermal growth factor receptor (EGFR), with a DC50 of less than 100 nM. It binds to CRBN-DDB1 with a Ki of 36 nM. This compound effectively degrades EGFR, focal adhesion kinase (FAK), and RSK1, and inhibits the proliferation of BaF3 wild-type and EGFR mutant cells, exhibiting an IC50 of less than 100 nM.</p>Formula:C49H64ClFN10O7SColore e forma:SolidPeso molecolare:991.61EGFR/PI3Kα-IN-1
EGFR/PI3Kα-IN-1 (compound 30k), a dual EGFR/PI3Kα inhibitor, exhibits potent activity with IC 50 values of 3.6 nM (EGFRL858R/T790M) and 30 nM (PI3Kα). It effectively inhibits tumor cell proliferation and demonstrates significant anticancer activity.Formula:C50H49N11O5SColore e forma:SolidPeso molecolare:916.06[Pro3]-GIP (Mouse)
GIP receptor blocker, 2.6μM IC50, hinders insulin release, regulates glucose in ob/ob mice, and enhances glucose tolerance.Formula:C225H342N62O64SPurezza:98%Colore e forma:SolidPeso molecolare:4971.62ErbB-2-binding peptide
CAS:ErbB-2-binding peptide (HER2-binding peptide), a tumor-targeting peptide, holds potential for cancer research applications [1].Formula:C43H60N8O11Colore e forma:SolidPeso molecolare:864.98DDR Inhibitor 2
DDR Inhibitor 2 (compound 5a) is a potent inhibitor of the discoidin domain receptor (DDR) with an IC50 value of 0.125 μM, and it is applicable in fibrotic disease research.Formula:C21H23N7OColore e forma:SolidPeso molecolare:389.19641EGFR-IN-140
EGFR-IN-140 (Compound 31) is an inhibitor of EGFR, effectively targeting both wild-type EGFR and the EGFRL858R/T790M/C797S mutant, with Ki values of 0.95 nM and 2.1 nM, respectively. Additionally, it inhibits EGFRdel19/T790M/C797S in Ba/F3 cells with an IC50 of 56.9 nM and demonstrates antitumor activity in mouse models.Formula:C27H37FN8O2Colore e forma:SolidPeso molecolare:524.633Matuzumab
CAS:Matuzumab (EMD 72000) is a humanized monoclonal antibody targeting EGFR that can be used to study non-small cell lung cancer.Purezza:95%Colore e forma:LiquidPeso molecolare:145.9 kDaTaletrectinib free base
CAS:Taletrectinib (AB-106) is a potent, selective oral ROS1/NTRK inhibitor with low IC50s against ROS1 and NTRK1-3, including Crizotinib-resistant mutations.Formula:C23H24FN5OPurezza:99.98%Colore e forma:SolidPeso molecolare:405.47Ref: TM-T38995
1mg71,00€5mg157,00€10mg243,00€25mg487,00€50mg705,00€100mg998,00€1mL*10mM (DMSO)183,00€cis-NVP-ADW742
CAS:NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.Formula:C28H31N5OColore e forma:SolidPeso molecolare:453.59WAY-270360
CAS:WAY-270360 (N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide) is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor.Formula:C22H19N3O3Purezza:98.05%Colore e forma:SolidPeso molecolare:373.4[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)
CAS:Insulin Receptor (1142-1153) binds insulin, is a substrate for its kinase, and has research/medical potential.Formula:C72H110N19O33P3Purezza:98%Colore e forma:SolidPeso molecolare:1862.67EGFR T790M/L858R-IN-6
CAS:EGFR T790M/L858R-IN-6 (compound 53), classified as a pyrimidine compound, serves as an effective inhibitor of EGFR T790M/L858R, demonstrating 90.88% inhibition of enzyme activity at a concentration of 0.05 μM [1].Formula:C27H27N7O2Colore e forma:SolidPeso molecolare:481.55EGFR kinase inhibitor 2
EGFR kinase inhibitor 2 (compound A-7) is a potent EGFR inhibitor targeting the mutations EGFRL858R/T790M/C797S and EGFRDel19/T790M/C797S. This compound shows potential in addressing acquired resistance in the treatment of non-small cell lung cancer.Formula:C39H40N6O5Peso molecolare:672.30602PF-04217903 phenolsulfonate
CAS:PF-04217903 phenolsulfonate is a potent ATP-competitive inhibitor of c-Met kinase (Ki of 4.8 nM for human c-Met).Formula:C25H22N8O5SPurezza:98%Colore e forma:SolidPeso molecolare:546.56GW 583340
CAS:GW 583340 is a potent and selective dual inhibitor of EGFR/ErbB2 tyrosine kinase with the advantage of oral dosability and antitumor effects.Formula:C28H25ClFN5O3S2Purezza:98.68%Colore e forma:SoildPeso molecolare:598.11Ref: TM-T22827L
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€200mg2.555,00€EGFR-IN-93
EGFR-IN-93 (compound 18) is an allosteric inhibitor of the T790M/L858R double mutant EGFR. It is applicable for research in non-small cell lung cancer (NSCLC).Formula:C22H18FN3O3Peso molecolare:391.13322Insulin efsitora alfa
CAS:Insulin efsitora alfa(LY-3209590) is an IR agonist and a fusion protein that binds a novel single-chain insulin variant to the structural domain of human IgG FcPurezza:98.3% (SDS-PAGE); 98.1% (SEC-HPLC) - 98.3% (SDS-PAGE); 98.1% (SEC-HPLC)Colore e forma:LiquidPeso molecolare:32.04 kDaPertuzumab
CAS:Pertuzumab (anti-HER2) a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2Purezza:98.00%Colore e forma:LiquidPeso molecolare:148 kDaEGFR WT/T790M/L858R-IN-1
EGFRWT/T790M/L858R-IN-1 (compound 10d) is a potent inhibitor of EGFR, demonstrating IC50 values of 0.097, 0.280, and 0.051 μM for EGFRWT, EGFRT790M, and EGFRL858R, respectively. This compound can be utilized in cancer research.Formula:C26H25Cl3N2O3Peso molecolare:518.09308Timigutuzumab
CAS:Timigutuzumab (GEXMab73) is a humanized monoclonal antibody designed to target ErbB2, showing potential application in cancer research [1].Colore e forma:LiquidZenocutuzumab
CAS:Zenocutuzumab (MCLA-128) is a humanized antibody targeting HER2, used for research on tumors driven by NRG1 gene rearrangement.Purezza:97%Colore e forma:LiquidPeso molecolare:145.76 kDaPKA Inhibitor Fragment (6-22) amide TFA
PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) is an inhibitor of cAMP-dependent protein kinase A (PKA).Formula:C82H131F3N28O26Purezza:99.61% - 99.87%Colore e forma:SolidPeso molecolare:1982.08EGFR-IN-95
EGFR-IN-95 is a derivative of 2,4-diaminonicotinamide. It effectively inhibits the activity of EGFRdel19/T790M/C797S and L858R/T790M/C797S.Formula:C23H28F2N8O3SPeso molecolare:534.19731MS39N
CAS:<p>MS39N (compound 27) serves as the negative control for MS39, capable of binding to EGFR without causing its degradation.</p>Formula:C55H71ClFN9O7SPeso molecolare:1056.73MS9449
CAS:MS9449 is a powerful EGFR PROTAC; Kd: 17 nM (WT), 10 nM (L858R); targets mutant EGFRs via UPS and autophagy; hinders NSCLC cell growth.Formula:C60H76ClFN10O8SPurezza:98%Colore e forma:SolidPeso molecolare:1151.82Kemptide Phospho-Ser5
Kemptide (Phospho-Ser5) is a phosphoreceptor peptide that is a specific substrate for camp-dependent protein kinase (PKA).Formula:C32H62N13O12PPurezza:98%Colore e forma:SolidPeso molecolare:851.89MS9427 TFA
MS9427 TFA: PROTAC EGFR degrader, Kd 7.1 nM (WT), 4.3 nM (L858R), targets mutant EGFR, inhibits NSCLC cell growth, for cancer research.Formula:C50H59ClF4N8O14Colore e forma:SolidPeso molecolare:1107.5Eflapegrastim
CAS:Eflapegrastim: humanized IgG4 antibody and G-CSF that boosts neutrophils and shortens neutropenia.Colore e forma:LiquidVarlitinib
CAS:Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively.Formula:C22H19ClN6O2SPurezza:99.7%Colore e forma:SolidPeso molecolare:466.94HER2-IN-13
CAS:HER2-IN-13 (Compound 33) serves as an effective HER2 inhibitor, exhibiting an IC50 value of 8 nM, and additionally demonstrates inhibition of wt-EGFR with anFormula:C26H23ClF2N8O3Colore e forma:SolidPeso molecolare:568.96JBJ-09-063 TFA
JBJ-09-063 TFA, an EGFR inhibitor selective for EGFR mutations, IC50s: 0.147-0.396 nM, blocks EGFR/Akt/ERK signaling, for EGFR-mutant lung cancer research.Formula:C33H30F4N4O5SColore e forma:SolidPeso molecolare:670.67Gefitinib N-oxide hydrochloride
Gefitinib N-oxide hydrochloride is an N-oxide of EGFR inhibitor Gefitinib with IC50 of 2-37 nM.Formula:C22H24ClFN4O41·5HClColore e forma:SolidPeso molecolare:517.59DSPE-PEG5000-GE11
DSPE-PEG5000-GE11 is a PEG compound composed of DSPE and the EGFR-targeting peptide (GE11). GE11 is applicable for cancer cells with EGFR overexpression. DSPE-PEG5000-GE11 is utilized in drug delivery.Colore e forma:Odour SolidCompound TPX-0046
CAS:Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound TPX-0046 can be used for the research of cancer.Formula:C21H21FN6O3Purezza:99.94%Colore e forma:SoildPeso molecolare:424.43Sotuletinib hydrochloride
CAS:Sotuletinib hydrochloride (BLZ945 HCl) is a selective, brain-penetrant CSF-1R (c-Fms) inhibitor (IC50=1 nM),for ALS and TNBC.Formula:C20H23ClN4O3SPurezza:98.812%Colore e forma:SolidPeso molecolare:434.94SJF 1528
CAS:Potent EGFR & HER2 degrader; DC50 of 39.2 nM in OVCAR8, 736 nM in HeLa; has lapatinib, VHL ligand; inhibits HER2+ breast cancer (IC50=102 nM for SKBr3).Formula:C55H57ClFN7O8SColore e forma:SolidPeso molecolare:1030.61HER2-IN-20
HER2-IN-20 (compound 32) is a potent and selective inhibitor of HER2WT and HER2YVMA, with IC50 values of 49 and 42 nM, respectively. It holds potential for research in non-small cell lung cancer (NSCLC).Formula:C30H27ClFN7O2Peso molecolare:571.18988TrkA-IN-6
<p>TrkA-IN-6 (compound R48) is a hydrazone-based, selective inhibitor of the tropomyosin receptor kinase A (TrkA). It exhibits greater cytotoxicity towards U87 GBM cells compared to Temozolomide, with an IC50 of 68.99 μM.</p>Formula:C16H13N3O5Peso molecolare:327.08552EGFR-IN-15
CAS:EGFR-IN-15 (compound I-005) is a potent EGFR inhibitor, exhibiting an IC50 value of 4 nM. This compound holds potential for oncological research applications.Formula:C24H25BrN6O2Colore e forma:SolidPeso molecolare:509.408PKG Substrate
CAS:PKG Substrate is selective for PKG, favors PKG Iα (Km=59µM) over PKG II (Km=305µM).Formula:C35H67N17O11Purezza:98%Colore e forma:SolidPeso molecolare:902.01GIP, human
CAS:<p>Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.</p>Formula:C226H338N60O66SPurezza:98%Colore e forma:SolidPeso molecolare:4983.6Anti-ERBB3/HER3 (29Z6)
Anti-ERBB3/HER3 (29Z6) is an antibody inhibitor targeting human ERBB3/HER3.Colore e forma:Odour LiquidMC-Val-Cit-PAB-Amide-TLR7 agonist 4 Conjugate
CAS:MC-Val-Cit-PAB-Amide-TLR7 agonist 4 Conjugate is a conjugate formed by linking MC-Val-Cit-PAB-Amide and TLR7 agonist 4, useful for cancer research.Formula:C52H72N12O11Purezza:97.70%Colore e forma:SolidPeso molecolare:1041.2Istiratumab
CAS:Istiratumab (M-6495) is a bispecific antibody against IGF-1R/ErbB3 for cancer research, promoting receptor degradation.Colore e forma:LiquidCetuximab (PBS)
Cetuximab (PBS) is a human IgG1 monoclonal antibody that inhibits the epidermal growth factor receptor (EGFR), with a dissociation constant (Kd) of 0.201 nM for EGFR as measured by the SPR method. It exhibits potent antitumor activity.Colore e forma:Odour LiquidEGFR-IN-43
EGFR-IN-43 (17c) is a potent EGFR inhibitor with ER antagonist action, tamoxifen/endoxifen+gefitinib linkage, and strong anticancer activity.Formula:C50H55ClFN5O5Colore e forma:SolidPeso molecolare:860.45JAK1/2/3 Inhibitor 1
CAS:JAK1/2/3 Inhibitor 1 is a potent protein kinase inhibitor.JAK1/2/3 Inhibitor 1 has antitumor activity that inhibits the growth of a variety of cancer cell linesFormula:C6H2Cl2N2SPurezza:99.99%Colore e forma:SolidPeso molecolare:205.06EGFR-IN-76
CAS:EGFR-IN-76 is a potent EGFR inhibitor.Formula:C30H30ClFN6O2Purezza:97.02% - 97.72%Colore e forma:SolidPeso molecolare:561.05BMS-777607
CAS:BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3.Formula:C25H19ClF2N4O4Purezza:98.16% - 98.56%Colore e forma:SolidPeso molecolare:512.89Ref: TM-T2658
2mg63,00€5mg90,00€10mg142,00€25mg265,00€50mg409,00€100mg727,00€200mg1.091,00€500mg1.636,00€PD-360324
PD-360324 is a human monoclonal antibody (mAb) that targets CSF1/M-CSF. It can be utilized in research related to skin lupus, pulmonary sarcoidosis, and rheumatoid arthritis.Colore e forma:Odour LiquidDuligotuzumab
CAS:Duligotuzumab is a dual-targeting anti-EGFR/HER3 mAb that blocks signaling and induces ADCC for tumors with poor prognosis.Purezza:97.7% (SDS-PAGE); 96.3% (SEC-HPLC) - ≥95% (SDS-PAGE); 95.19% (SEC-HPLC)Colore e forma:LiquidHER2-IN-14
CAS:HER2-IN-14 (Compound 34) is a potent inhibitor of HER2, achieving an inhibitory concentration (IC50) of 18 nM.Formula:C26H23ClF2N8O3Colore e forma:SolidPeso molecolare:568.96ALW-II-49-7
CAS:<p>ALW-II-49-7 is a selective and potent inhibitor of EphB2 kinase with an EC50 value of 40 nM in cell.</p>Formula:C21H17F3N4O2Purezza:99.72%Colore e forma:SoildPeso molecolare:414.38
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