Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Avadomide HCl
CAS:<p>Avadomide (CC-122), an oral drug, targets CRBN, degrades Ikaros/Aiolos, and mimics interferon, showing antitumor effects in DLBCL.</p>Fórmula:C14H15ClN4O3Cor e Forma:SolidPeso molecular:322.75Actein
CAS:<p>Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.</p>Fórmula:C37H56O11Pureza:≥98%Cor e Forma:Brown PowderPeso molecular:676.83LYN-1604 hydrochloride
CAS:<p>LYN-1604 HCl activates ULK1 (EC50: 18.94 nM); key for studying TNBC.</p>Fórmula:C33H44Cl3N3O2Cor e Forma:SolidPeso molecular:621.08Desmorpholinyl Navitoclax-NH-Me
CAS:<p>Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a</p>Fórmula:C44H51ClF3N5O5S3Pureza:99.87%Cor e Forma:SolidPeso molecular:918.55Lenalidomide hemihydrate
CAS:<p>Lenalidomide hemihydrate inhibits TNF-α (IC50=13nM) and binds CRBN/DDB1 complexes.</p>Fórmula:C13H13N3O3H2OPureza:96.22%Cor e Forma:SolidPeso molecular:268.28Nutlin-3
CAS:<p>Nutlin-3 is an MDM2 antagonist that inhibits MDM2-p53 interaction and activates p53. Nutlin-3 has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C30H30Cl2N4O4Pureza:98.13% - 99.89%Cor e Forma:SolidPeso molecular:581.49Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Fórmula:C20H20N8Na2O5Pureza:99.77% - 99.96%Cor e Forma:SolidPeso molecular:498.4Coenzyme Q9
CAS:<p>Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma.</p>Fórmula:C54H82O4Pureza:98.2% - 99.47%Cor e Forma:SolidPeso molecular:795.23TW-37
CAS:<p>TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).</p>Fórmula:C33H35NO6SPureza:97.06% - ≥95%Cor e Forma:SolidPeso molecular:573.7Thalidomide-PEG4-Propargyl
CAS:<p>Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.</p>Fórmula:C24H28N2O9Pureza:97.46%Cor e Forma:SolidPeso molecular:488.49Mitochonic acid 5
CAS:<p>MA-5, derived from a plant hormone, binds mitochondria and reduces heart/kidney damage, aiding mitochondrial disease survival.</p>Fórmula:C18H13F2NO3Pureza:98.85%Cor e Forma:SolidPeso molecular:329.3Brevilin A
CAS:<p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>Fórmula:C20H26O5Pureza:99.97% - >99.99%Cor e Forma:SolidPeso molecular:346.42PUMA BH3 Free base
<p>PUMA BH3 acetate (PUMA BH3 Free base) is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd of</p>Fórmula:C130H206N42O45SPureza:96.64%Cor e Forma:SolidPeso molecular:3109.35Deltamethrin
CAS:<p>Deltamethrin, a pyrethroid insecticide, causes reversible hind limb rigidity in rats and is used for crop protection and disease control.</p>Fórmula:C22H19Br2NO3Pureza:99.25% - 99.85%Cor e Forma:White To Off-White Crystals Or PowderPeso molecular:505.20T-1101 tosylate
CAS:<p>T-1101 tosylate (TAI-95 tosylate) is an inhibitor of Hec1/Nek2, with antitumor activity.</p>Fórmula:C31H31N5O6S3Pureza:98.1%Cor e Forma:SolidPeso molecular:665.8PX-12
CAS:<p>PX-12, a Trx-1 inhibitor, promotes apoptosis, reduces HIF-1α/VEGF, and inhibits tumor growth, suggesting use in advanced cancer therapy.</p>Fórmula:C7H12N2S2Pureza:98% - 99.21%Cor e Forma:SolidPeso molecular:188.31Mycophenolate Mofetil
CAS:<p>Mycophenolate Mofetil (TM-MMF), is an immunosuppressive agent, 2-morpholinoethyl ester of MPA, and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).</p>Fórmula:C23H31NO7Pureza:98.27% - 99.85%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:433.49Fimasartan
CAS:<p>Fimasartan (BR-A-657), an ARB, treats hypertension and heart failure; safe with hydrochlorothiazide.</p>Fórmula:C27H31N7OSPureza:98.96%Cor e Forma:SolidPeso molecular:501.65Carfilzomib
CAS:<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>Fórmula:C40H57N5O7Pureza:99.6% - 99.84%Cor e Forma:SolidPeso molecular:719.914-Methyldaphnetin
CAS:<p>4-Methyldaphnetin (DHMC) is a potent inhibitor of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals.</p>Fórmula:C10H8O4Pureza:99.73%Cor e Forma:SolidPeso molecular:192.17Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Fórmula:C18H18N2O3Pureza:98.92% - 99.52%Cor e Forma:SolidPeso molecular:310.35Sclareol
CAS:<p>Sclareol from clary sage inhibits growth and is cytotoxic to many human Y cell lines.</p>Fórmula:C20H36O2Pureza:99.58% - 99.97%Cor e Forma:White Fine PowderPeso molecular:308.5NVP-TAE 226
CAS:<p>NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.</p>Fórmula:C23H25ClN6O3Pureza:98.07% - 98.78%Cor e Forma:SolidPeso molecular:468.94Ac-DEVD-pNA
CAS:<p>Ac-DEVD-pNA is the preferred peptidic substrate for caspase-3.</p>Fórmula:C26H34N6O13Pureza:>99.99%Cor e Forma:WhitePeso molecular:638.58K-Ras(G12C) inhibitor 12
CAS:<p>K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Fórmula:C15H17ClIN3O3Pureza:97.16%Cor e Forma:SolidPeso molecular:449.67LY-411575
CAS:<p>LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage.</p>Fórmula:C26H23F2N3O4Pureza:97.03% - 99.38%Cor e Forma:SolidPeso molecular:479.48(Rac)-Idroxioleic acid
CAS:<p>(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor effect.</p>Fórmula:C18H34O3Pureza:≥98%Cor e Forma:SolidPeso molecular:298.46Ripretinib
CAS:<p>Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.</p>Fórmula:C24H21BrFN5O2Pureza:99.07% - 99.38%Cor e Forma:SolidPeso molecular:510.36OsMundacetone
CAS:<p>OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.</p>Fórmula:C10H10O3Pureza:99.59% - ≥95%Cor e Forma:SolidPeso molecular:178.18(20S)-Protopanaxatriol
CAS:<p>(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid</p>Fórmula:C30H52O4Pureza:95% - 99%Cor e Forma:SolidPeso molecular:476.73Angelicin
CAS:<p>Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.</p>Fórmula:C11H6O3Pureza:99.86% - 99.89%Cor e Forma:White SolidPeso molecular:186.16Rabeprazole sodium
CAS:<p>Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.</p>Fórmula:C18H20N3NaO3SPureza:98% - 99.912%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:381.42DL-Buthionine-(S,R)-sulfoximine
CAS:<p>DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.</p>Fórmula:C8H18N2O3SPureza:98% - 99.64%Cor e Forma:White Fine PowderPeso molecular:222.31Cilengitide
CAS:<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Fórmula:C27H40N8O7Pureza:98% - 99.8%Cor e Forma:SolidPeso molecular:588.665'-Methylthioadenosine
CAS:<p>5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product.</p>Fórmula:C11H15N5O3SPureza:99.32% - 99.34%Cor e Forma:SolidPeso molecular:297.33Avitinib maleate
CAS:<p>Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.</p>Fórmula:C30H30FN7O6Pureza:98% - 99.74%Cor e Forma:SolidPeso molecular:603.61Prosapogenin A
CAS:<p>Prosapogenin A (Progenin III) has anticancer activity.</p>Fórmula:C39H62O12Pureza:99.60% - 99.75%Cor e Forma:SolidPeso molecular:722.9DMU-212
CAS:<p>DMU-212, a Resveratrol derivative, has antimitotic, antiproliferative, antioxidant properties; induces apoptosis via ERK1/2.</p>Fórmula:C18H20O4Pureza:99.86%Cor e Forma:SolidPeso molecular:300.35Millepachine
CAS:<p>Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.</p>Fórmula:C22H22O4Pureza:99.73%Cor e Forma:SolidPeso molecular:350.41Navtemadlin
CAS:<p>Navtemadlin (AMG232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM).Cost-effective and quality-assured.</p>Fórmula:C28H35Cl2NO5SPureza:95.55% - 99.08%Cor e Forma:SolidPeso molecular:568.55Paederosidic acid
CAS:<p>Paederosidic acid shows anti-tumor, anticonvulsant, and sedative properties, may treat epilepsy by modulating brain GABA and glutamate levels.</p>Fórmula:C18H24O12SPureza:98% - 99.56%Cor e Forma:SolidPeso molecular:464.44DEL-22379
CAS:<p>DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ～0.5 μM.</p>Fórmula:C26H28N4O3Pureza:99.3% - 99.53%Cor e Forma:SolidPeso molecular:444.53Crebanine
CAS:<p>Crebanine mitigates arrhythmias, increases aconitine tolerance in rats, lacks effect on ouabain-induce arrhythmias, and shows anti-cancer properties.</p>Fórmula:C20H21NO4Pureza:99.17% - 99.77%Cor e Forma:SolidPeso molecular:339.39M50054
CAS:<p>Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.</p>Fórmula:C13H16O4Pureza:97.8%Cor e Forma:SolidPeso molecular:236.26Fluazinam
CAS:<p>Fluazinam: a pyridinamine fungicide, broad-spectrum, strongly inhibits S. sclerotiorum mycelial growth.</p>Fórmula:C13H4Cl2F6N4O4Pureza:98% - 99.7%Cor e Forma:Light Yellow CrystalsPeso molecular:465.09Laquinimod sodium
CAS:<p>Laquinimod (ABR-215062) sodium is an oral agent for MS, halting neurodegeneration and inflammation.</p>Fórmula:C19H16ClN2NaO3Cor e Forma:SolidPeso molecular:378.79Hispidol
CAS:<p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>Fórmula:C15H10O4Pureza:97.86% - 98.45%Cor e Forma:SolidPeso molecular:254.24Ligustrazine
CAS:<p>Ligustrazine (Tetramethylpyrazine), a natural compound isolated from Chuan Xiong shows anti-inflammation, antioxidant, antiplatelet, and antiapoptosis effects.</p>Fórmula:C8H12N2Pureza:99.91% - >99.99%Cor e Forma:White Crystals Or PowderPeso molecular:136.19Pomolic acid
CAS:<p>Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-</p>Fórmula:C30H48O4Pureza:96.84% - 99.79%Cor e Forma:SolidPeso molecular:472.7Ferrostatin-1
CAS:<p>Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of iron death, potently inhibits Erastin-induced iron death in HT-1080 cells. High-Quality, Low-Cost!</p>Fórmula:C15H22N2O2Pureza:96.1% - 99.68%Cor e Forma:SolidPeso molecular:262.35Romidepsin
CAS:<p>Romidepsin (NSC-630176), an IV histone deacetylase inhibitor, treats refractory cutaneous/peripheral T-cell lymphomas.</p>Fórmula:C24H36N4O6S2Pureza:99.4% - 99.94%Cor e Forma:SolidPeso molecular:540.7Dihydrocapsaicin
CAS:<p>Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.</p>Fórmula:C18H29NO3Pureza:99.61% - ≥95%Cor e Forma:White CrystalPeso molecular:307.43Ralimetinib dimesylate
CAS:<p>Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.</p>Fórmula:C24H29FN6·2CH4O3SPureza:98% - 99.38%Cor e Forma:SolidPeso molecular:612.74Bromosporine
CAS:<p>Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.</p>Fórmula:C17H20N6O4SPureza:99.65% - 99.79%Cor e Forma:SolidPeso molecular:404.44GSK-J4
CAS:<p>GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.</p>Fórmula:C24H27N5O2Pureza:98.24% - 99.98%Cor e Forma:SolidPeso molecular:417.5Thalidomide-O-C4-NH2 hydrochloride
CAS:<p>Thalidomide-linker 9: a cereblon ligand, E3 ligase conjugate for PROTAC tech.</p>Fórmula:C17H20ClN3O5Pureza:98.33%Cor e Forma:SolidPeso molecular:381.81Bardoxolone
CAS:<p>Bardoxolone (CDDO) inhibits iNOS, COX-2 in cells; IC50=0.4nM. Reduces ROS/RNS, DNA damage, & cancer growth; triggers apoptosis & boosts antioxidant genes.</p>Fórmula:C31H41NO4Pureza:97.9% - 98.97%Cor e Forma:SolidPeso molecular:491.66Prucalopride Succinate
CAS:<p>Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).</p>Fórmula:C18H26ClN3O3·C4H6O4Pureza:99.24%Cor e Forma:SolidPeso molecular:485.96Capmatinib 2HCl.H2O
CAS:<p>Capmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.</p>Fórmula:C23H21Cl2FN6O2Pureza:99.77%Cor e Forma:SolidPeso molecular:503.36Fipronil
CAS:<p>Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.</p>Fórmula:C12H4Cl2F6N4OSPureza:97.21%Cor e Forma:Solid PowderPeso molecular:437.15Helichrysetin
CAS:<p>Helichrysetin shows mild anti-HIV-1 activity and potential as an anticancer agent with cytotoxic effects on A549, MCF-7, Ca Ski, HT-29 cells.</p>Fórmula:C16H14O5Pureza:96.32% - ≥95%Cor e Forma:SolidPeso molecular:286.28Abacavir sulfate
CAS:<p>Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity</p>Fórmula:C14H18N6OH2O4SPureza:99.79% - 99.85%Cor e Forma:White To Off-White SolidPeso molecular:335.38Eprenetapopt
CAS:<p>Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.</p>Fórmula:C10H17NO3Pureza:98.75% - 99.57%Cor e Forma:SolidPeso molecular:199.25PYR-41
CAS:<p>PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.</p>Fórmula:C17H13N3O7Pureza:98.25%Cor e Forma:SolidPeso molecular:371.3KX2-361
CAS:<p>KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma</p>Fórmula:C24H24FN3O2Pureza:99.64% - 99.68%Cor e Forma:SolidPeso molecular:405.46QNZ
CAS:<p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>Fórmula:C22H20N4OPureza:99.17% - 99.18%Cor e Forma:White SolidPeso molecular:356.42Epoxomicin
CAS:<p>Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.</p>Fórmula:C28H50N4O7Pureza:98.65% - 98.86%Cor e Forma:White To Off-White SolidPeso molecular:554.72Flavokawain B
CAS:<p>Flavokawain B inhibits NO and PGE2, causes oxidative stress, and induces apoptosis, with potential for treating prostate cancer.</p>Fórmula:C17H16O4Pureza:99.97% - >99.99%Cor e Forma:SolidPeso molecular:284.31Tandutinib
CAS:<p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>Fórmula:C31H42N6O4Pureza:99.45% - ≥98%Cor e Forma:White SolidPeso molecular:562.7MS7972
CAS:<p>MS7972 is CREBBP inhibitor that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM</p>Fórmula:C14H13NO2Pureza:99.78%Cor e Forma:SolidPeso molecular:227.26JKE-1674
CAS:<p>JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.</p>Fórmula:C20H20Cl2N4O4Pureza:98.02% - 98.4%Cor e Forma:SolidPeso molecular:451.3LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Fórmula:C19H17NO3Pureza:98% - 99.96%Cor e Forma:Pale Yellow SolidPeso molecular:307.34AG1024
CAS:<p>AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).</p>Fórmula:C14H13BrN2OPureza:98% - 99.37%Cor e Forma:SolidPeso molecular:305.17Rosiglitazone potassium
CAS:<p>Rosiglitazone (BRL 49653) is an oral PPARγ agonist (EC50: 60 nM), TRPC5 activator (EC50: 30 μM), and TRPM3 inhibitor, used in obesity and diabetes research.</p>Fórmula:C18H18KN3O3SCor e Forma:SolidPeso molecular:395.52Epieriocalyxin A
CAS:<p>Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future.</p>Fórmula:C20H24O5Pureza:97.00%Cor e Forma:SolidPeso molecular:344.4TPCK
CAS:<p>TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis</p>Fórmula:C17H18ClNO3SPureza:97.33%Cor e Forma:PowderPeso molecular:351.85Cystamine dihydrochloride
CAS:<p>Cystamine dihydrochloride is a radiation-protective agent. It also protects against carbon tetrachloride liver damage.</p>Fórmula:C4H14Cl2N2S2Pureza:98.91% - 99.81%Cor e Forma:White PowderPeso molecular:225.19Nelarabine
CAS:<p>Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.</p>Fórmula:C11H15N5O5Pureza:98.10% - 99.6%Cor e Forma:White SolidPeso molecular:297.27BML-210
CAS:<p>BML-210 (CAY10433) is a new-type HDAC inhibitor.</p>Fórmula:C20H25N3O2Pureza:96.37% - 98.12%Cor e Forma:SolidPeso molecular:339.43IMT1
CAS:<p>IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.</p>Fórmula:C21H21NO4Pureza:98.07% - 98.14%Cor e Forma:SolidPeso molecular:351.4Trifloxystrobin
CAS:<p>Trifloxystrobin is a fungicide against R. solani in sugar beets with EC50s: 23.0 μg/L for Daphnia neonates, 1.7 μg/L for embryos.</p>Fórmula:C20H19F3N2O4Pureza:99.49%Cor e Forma:SolidPeso molecular:408.37Triptonide
CAS:<p>Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.</p>Fórmula:C20H22O6Pureza:99.11% - 99.64%Cor e Forma:White Crystalline PowderPeso molecular:358.39RAF265
CAS:<p>RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.</p>Fórmula:C24H16F6N6OPureza:99.56%Cor e Forma:SolidPeso molecular:518.41PFI-90
CAS:<p>PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity.</p>Fórmula:C11H10N4OPureza:99.46%Cor e Forma:SolidPeso molecular:214.22LASSBio-1135
CAS:<p>LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.</p>Fórmula:C18H14N4Pureza:99.09%Cor e Forma:SolidPeso molecular:286.33Isosorbide Mononitrate
CAS:<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Fórmula:C6H9NO6Pureza:98.16%Cor e Forma:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionPeso molecular:191.14Parcetasal
CAS:<p>Parcetasal (MR-897) is a non-steroidal anti-inflammatory agent that can be used in pain relief studies.</p>Fórmula:C17H15NO5Pureza:99.07%Cor e Forma:SolidPeso molecular:313.3Thalidomide-O-amido-PEG2-C2-NH2 TFA
CAS:<p>Thalidomide-based E3 ligase ligand-linker for PROTAC with PEG2 bridge; cereblon-targeted.</p>Fórmula:C23H27F3N4O10Pureza:95.74% - 99%Cor e Forma:SolidPeso molecular:576.48Diclofenac Potassium
CAS:<p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>Fórmula:C14H10Cl2KNO2Pureza:99.51%Cor e Forma:White To Yellowish Crystalline PowderPeso molecular:334.24ERK1/2 inhibitor 2
CAS:<p>ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable ERK 1/2 inhibitor, with potential antineoplastic activity.</p>Fórmula:C29H31ClFN5O5Pureza:98.99%Cor e Forma:SolidPeso molecular:584.04PS-1145
CAS:<p>PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.</p>Fórmula:C17H11ClN4OPureza:98.81% - >99.99%Cor e Forma:SolidPeso molecular:322.75CCF642
CAS:<p>CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.</p>Fórmula:C15H10N2O4S3Pureza:97.12% - 98.82%Cor e Forma:SolidPeso molecular:378.45(ZE)-SU9516
CAS:<p>(ZE)-SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.</p>Fórmula:C13H11N3O2Pureza:99.59%Cor e Forma:SolidPeso molecular:241.25Isolongifolene
CAS:<p>Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, and</p>Fórmula:C15H24Pureza:90.13% - 99.46%Cor e Forma:Colorless Or Light Yellow LiquidPeso molecular:204.35Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Fórmula:C26H44NNaO6SPureza:98.23% - 99.45%Cor e Forma:White To Off-White PowderPeso molecular:521.68GSK4112
CAS:<p>GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.</p>Fórmula:C18H21ClN2O4SPureza:99.69%Cor e Forma:SolidPeso molecular:396.89Quinidine sulfate dihydrate
CAS:<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Fórmula:C40H54N4O10SPureza:99.85%Cor e Forma:White To Light Yellow Crystal PowdePeso molecular:782.9CM-272
CAS:<p>CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.</p>Fórmula:C28H38N4O3Pureza:97.83%Cor e Forma:SolidPeso molecular:478.63Pemetrexed disodium hemipenta hydrate
CAS:<p>Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.</p>Fórmula:C20H21N5O6·2NaH2OPureza:98.76%Cor e Forma:SolidPeso molecular:518.43CDPPB
CAS:<p>CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).</p>Fórmula:C23H16N4OPureza:99.16%Cor e Forma:SolidPeso molecular:364.4
