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Apoptose

Apoptose

Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.

Subcategorias de "Apoptose"

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Foram encontrados 5592 produtos de "Apoptose"

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  • BAM7

    CAS:
    <p>BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).</p>
    Fórmula:C21H19N5O2S
    Pureza:98.51% - 98.68%
    Cor e Forma:Solid
    Peso molecular:405.47
  • Glyphosate

    CAS:
    <p>Glyphosate (Atila) is an herbicide. It also is a possible carcinogen to humans.</p>
    Fórmula:C3H8NO5P
    Pureza:99.12% - 99.91%
    Cor e Forma:White Crystals (Darkens) Ph (1% Solution In Water) 2 5 (Ntp 1992)
    Peso molecular:169.07
  • GSK621

    CAS:
    <p>GSK621 is a specific and potent AMPK activator.</p>
    Fórmula:C26H20ClN3O5
    Pureza:97.02% - 97.05%
    Cor e Forma:Solid
    Peso molecular:489.91
  • Sodium Oxamate

    CAS:
    <p>Sodium Oxamate (Oxamic acid sodium salt) is an LDH inhibitor that specifically inhibits LDHA.</p>
    Fórmula:C2H2NNaO3
    Pureza:99.23% - ≥98%
    Cor e Forma:White Crystalline Powder
    Peso molecular:111.03
  • SC99

    CAS:
    <p>SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.</p>
    Fórmula:C15H8Cl2FN3O
    Pureza:99.56%
    Cor e Forma:Solid
    Peso molecular:336.15
  • Cichoric Acid

    CAS:
    <p>Cichoric Acid (Dicaffeoyltartaric acid) is a potent inhibitor of human immunodeficiency virus type-1 (HIV-1) integrase and the replication in tissues.</p>
    Fórmula:C22H18O12
    Pureza:97.87% - 98.77%
    Cor e Forma:Solid
    Peso molecular:474.37
  • BML-210

    CAS:
    <p>BML-210 (CAY10433) is a new-type HDAC inhibitor.</p>
    Fórmula:C20H25N3O2
    Pureza:96.37% - 98.12%
    Cor e Forma:Solid
    Peso molecular:339.43
  • Prosapogenin A

    CAS:
    <p>Prosapogenin A (Progenin III) has anticancer activity.</p>
    Fórmula:C39H62O12
    Pureza:99.60% - 99.75%
    Cor e Forma:Solid
    Peso molecular:722.9
  • Ripretinib

    CAS:
    <p>Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.</p>
    Fórmula:C24H21BrFN5O2
    Pureza:99.07% - 99.38%
    Cor e Forma:Solid
    Peso molecular:510.36
  • T-1101 tosylate

    CAS:
    <p>T-1101 tosylate (TAI-95 tosylate) is an inhibitor of Hec1/Nek2, with antitumor activity.</p>
    Fórmula:C31H31N5O6S3
    Pureza:98.1%
    Cor e Forma:Solid
    Peso molecular:665.8
  • Coenzyme Q9

    CAS:
    <p>Coenzyme Q9 (Ubiquinone 9) (CoQ9) is a normal constituent of human plasma.</p>
    Fórmula:C54H82O4
    Pureza:98.2% - 99.47%
    Cor e Forma:Solid
    Peso molecular:795.23
  • Chelerythrine chloride

    CAS:
    <p>Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to</p>
    Fórmula:C21H18ClNO4
    Pureza:95% - 99.19%
    Cor e Forma:Yellow To Orange Solid
    Peso molecular:383.83
  • Amuvatinib

    CAS:
    <p>Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.</p>
    Fórmula:C23H21N5O3S
    Pureza:99.38% - >99.99%
    Cor e Forma:Solid
    Peso molecular:447.51
  • DAPK Substrate Peptide acetate


    <p>DAPK Substrate Peptide acetate is a death-associated protein kinase (DAPK, Km = 9 μM) peptide substrate.</p>
    Fórmula:C70H115N25O17
    Pureza:98.12%
    Cor e Forma:Solid
    Peso molecular:1578.82
  • Concanavalin A

    CAS:
    <p>Concanavalin A is a natural product, a phytoalexin. Concanavalin A has antitumor activity and can also induce acute liver injury. Cost effective and quality assured.</p>
    Fórmula:C23H32N6O8S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:104-112 kDa
  • PHA-665752

    CAS:
    <p>PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), &gt;50-fold selectivity for c-Met than STKs or RTKs.</p>
    Fórmula:C32H34Cl2N4O4S
    Pureza:97.05% - 98.82%
    Cor e Forma:Solid
    Peso molecular:641.61
  • Notopterol

    CAS:
    <p>1. Notopterol induces apoptosis and inhibits cell cycle-specific.</p>
    Fórmula:C21H22O5
    Pureza:97.57% - 99.82%
    Cor e Forma:Solid
    Peso molecular:354.4
  • VR23

    CAS:
    <p>VR23: Potent proteasome inhibitor; IC50: 1 nM trypsin, 50-100 nM chymotrypsin, 3 μM caspase-like.</p>
    Fórmula:C19H16ClN5O6S
    Pureza:98.99% - 99.22%
    Cor e Forma:Solid
    Peso molecular:477.88
  • Caffeic Acid Phenethyl Ester

    CAS:
    <p>CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.</p>
    Fórmula:C17H16O4
    Pureza:99.18% - 99.35%
    Cor e Forma:Less Transparent Liquid Colorless Transparent Liquid
    Peso molecular:284.31
  • HBX 41108

    CAS:
    <p>HBX 41108: non-competitive, reversible USP7 inhibitor; IC50: 424nM; blocks USP7-p53 deubiquitination; IC50: 0.8μM.</p>
    Fórmula:C13H3ClN4O
    Pureza:95.63%
    Cor e Forma:Solid
    Peso molecular:266.64
  • CGP 57380

    CAS:
    <p>CGP 57380 (MNK1 Inhibitor) is a potent MNK1 inhibitor with IC50 of 2.2 μM, exhibiting no inhibitory activity on p38, JNK1, ERK1 and -2, PKC, or c-Src-like</p>
    Fórmula:C11H9FN6
    Pureza:98.49%
    Cor e Forma:Solid
    Peso molecular:244.23
  • (Z)-Guggulsterone

    CAS:
    <p>(Z)-Guggulsterone triggers apoptosis in prostate cancer cells and blocks angiogenesis by inhibiting VEGF pathways.</p>
    Fórmula:C21H28O2
    Pureza:98.93% - 99.72%
    Cor e Forma:Solid
    Peso molecular:312.45
  • NSC348884

    CAS:
    <p>NSC348884, a nucleophosmin inhibitor, disrupts oligomers, induces apoptosis, and inhibits cancer cell growth (IC50: 1.7-4.0 μM).</p>
    Fórmula:C38H40N10
    Pureza:98.69% - 99.91%
    Cor e Forma:Solid
    Peso molecular:636.79
  • Berbamine dihydrochloride

    CAS:
    <p>Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.</p>
    Fórmula:C37H42Cl2N2O6
    Pureza:95% - 99.99%
    Cor e Forma:Solid
    Peso molecular:681.65
  • Scoulerine

    CAS:
    <p>Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).</p>
    Fórmula:C19H21NO4
    Pureza:98.62%
    Cor e Forma:Solid
    Peso molecular:327.37
  • SP-141

    CAS:
    <p>SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.</p>
    Fórmula:C22H16N2O
    Pureza:98.01%
    Cor e Forma:Solid
    Peso molecular:324.38
  • BIO-acetoxime

    CAS:
    <p>BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, &gt;240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.</p>
    Fórmula:C18H12BrN3O3
    Pureza:97.15%
    Cor e Forma:Solid
    Peso molecular:398.21
  • 5,​7,​4'-​Trimethoxyflavone

    CAS:
    <p>5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.</p>
    Fórmula:C18H16O5
    Pureza:97.53%
    Cor e Forma:Solid
    Peso molecular:312.32
  • Dehydroeffusol

    CAS:
    <p>Dehydroeffusol: anti-cancer, anxiolytic, sedative; halts gastric cancer growth via ER stress and apoptosis.</p>
    Fórmula:C17H14O2
    Pureza:99.35%
    Cor e Forma:Solid
    Peso molecular:250.29
  • Domatinostat tosylate

    CAS:
    <p>4SC-202 is a class I HDAC inhibitor targeting HDAC1/2/3; shows activity against LSD1. IC50: HDAC1 (1.20 μM), HDAC2 (1.12 μM), HDAC3 (0.57 μM).</p>
    Fórmula:C30H29N5O6S2
    Pureza:97.35% - >99.99%
    Cor e Forma:Solid Powder
    Peso molecular:619.71
  • Spautin-1

    CAS:
    <p>Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.</p>
    Fórmula:C15H11F2N3
    Pureza:97.69% - 98.99%
    Cor e Forma:Solid
    Peso molecular:271.26
  • AKT inhibitor VIII

    CAS:
    <p>AKT inhibitor VIII (AKTi-1/2) is a highly specific Akt1/2 inhibitor (IC50: 58/210 nM). The selectivity for Akt1 is higher about 36-fold than Akt3.</p>
    Fórmula:C34H29N7O
    Pureza:98.31% - 98.65%
    Cor e Forma:Pale Yellow Solid
    Peso molecular:551.64
  • LJH685

    CAS:
    <p>LJH685 is an effective pan-RSK inhibitor for RSK1/2/3 (IC50: 6/5/4 nM).</p>
    Fórmula:C22H21F2N3O
    Pureza:99.13% - 99.78%
    Cor e Forma:Solid
    Peso molecular:381.42
  • PF-543 hydrochloride

    CAS:
    <p>PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2</p>
    Fórmula:C27H32ClNO4S
    Pureza:98.9% - 99.93%
    Cor e Forma:Solid
    Peso molecular:502.1
  • Sesamol

    CAS:
    <p>Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats.</p>
    Fórmula:C7H6O3
    Pureza:99.67% - 99.76%
    Cor e Forma:White To Off-White Crystalline Powder
    Peso molecular:138.12
  • Ginsenoside F5

    CAS:
    <p>Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway</p>
    Fórmula:C41H70O13
    Pureza:99.78% - 99.86%
    Cor e Forma:Solid
    Peso molecular:770.99
  • Paris saponin VII

    CAS:
    <p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>
    Fórmula:C51H82O21
    Pureza:99.51% - 99.63%
    Cor e Forma:Solid
    Peso molecular:1031.18
  • Sophoridine

    CAS:
    <p>Sophoridine, a natural Chinese anticancer drug, has a potent derivative 6b targeting DNA topoisomerase I in tumor cells, inducing apoptosis.</p>
    Fórmula:C15H24N2O
    Pureza:97.33% - 99.28%
    Cor e Forma:Solid
    Peso molecular:248.36
  • DBEQ

    CAS:
    <p>DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.</p>
    Fórmula:C22H20N4
    Pureza:98.93% - ≥95%
    Cor e Forma:Solid
    Peso molecular:340.42
  • AZD5582 acetate (1258392-53-8 free base)


    <p>AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.</p>
    Fórmula:C60H82N8O10
    Pureza:97.76%
    Cor e Forma:Solid
    Peso molecular:1075.36
  • Dipyrithione

    CAS:
    <p>Dipyrithione appears to have novel cytotoxicity and potent broad-spectrum antitumor activity</p>
    Fórmula:C10H8N2O2S2
    Pureza:99.9%
    Cor e Forma:Beige Crystalline Powder
    Peso molecular:252.31
  • Phenoxodiol

    CAS:
    <p>Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)</p>
    Fórmula:C15H12O3
    Pureza:98.07%
    Cor e Forma:Solid
    Peso molecular:240.25
  • Anisomycin

    CAS:
    <p>Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.</p>
    Fórmula:C14H19NO4
    Pureza:98.33% - 99.81%
    Cor e Forma:White Crystalline Solid
    Peso molecular:265.3
  • ARS-853

    CAS:
    <p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>
    Fórmula:C22H29ClN4O3
    Pureza:97.43% - 98.4%
    Cor e Forma:Solid
    Peso molecular:432.94
  • Lorlatinib

    CAS:
    <p>Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene</p>
    Fórmula:C21H19FN6O2
    Pureza:99.77% - 99.95%
    Cor e Forma:Solid
    Peso molecular:406.41
  • Carvacrol

    CAS:
    <p>1.</p>
    Fórmula:C10H14O
    Pureza:99.05%
    Cor e Forma:Needles Liquid
    Peso molecular:150.22
  • MFCD01917484

    CAS:
    <p>MFCD01917484: A thiophene derivative with ligand, catalyst, and photosensitizer roles, used in biochemical research and drug development.</p>
    Fórmula:C14H15NO3S
    Pureza:98.09%
    Cor e Forma:Solid
    Peso molecular:277.34
  • Taccalonolide A

    CAS:
    <p>Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is</p>
    Fórmula:C36H46O14
    Pureza:98.16% - 99.4%
    Cor e Forma:Solid
    Peso molecular:702.74
  • Onatasertib

    CAS:
    <p>Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.</p>
    Fórmula:C21H27N5O3
    Pureza:99.14% - 99.97%
    Cor e Forma:Solid
    Peso molecular:397.47
  • β-Elemonic Acid

    CAS:
    <p>β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.</p>
    Fórmula:C30H46O3
    Pureza:99.61% - 99.8%
    Cor e Forma:Solid
    Peso molecular:454.68
  • BAY 11-7082

    CAS:
    <p>BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).</p>
    Fórmula:C10H9NO2S
    Pureza:98% - 99.92%
    Cor e Forma:Solid
    Peso molecular:207.25
  • (6R)-FR054

    CAS:
    <p>(6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.</p>
    Fórmula:C14H19NO8
    Pureza:99.61%
    Cor e Forma:Solid
    Peso molecular:329.3
  • (-)-Epipodophyllotoxin

    CAS:
    <p>(-)-Epipodophyllotoxin: anticancer, GI50=0.36μM (HeLa), 0.24μM (MCF-7), inhibits spindle assembly.</p>
    Fórmula:C22H22O8
    Pureza:99.97%
    Cor e Forma:Solid
    Peso molecular:414.41
  • PD173074

    CAS:
    <p>PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.</p>
    Fórmula:C28H41N7O3
    Pureza:98.15% - 98.21%
    Cor e Forma:Yellow Solid
    Peso molecular:523.67
  • JNJ-7706621

    CAS:
    <p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>
    Fórmula:C15H12F2N6O3S
    Pureza:99.1% - 99.85%
    Cor e Forma:Solid
    Peso molecular:394.36
  • WP1066

    CAS:
    <p>WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.</p>
    Fórmula:C17H14BrN3O
    Pureza:98.92% - 99.73%
    Cor e Forma:Solid
    Peso molecular:356.22
  • Gemcitabine hydrochloride

    CAS:
    <p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>
    Fórmula:C9H11F2N3O4·HCl
    Pureza:99.28% - 99.98%
    Cor e Forma:White Crystalline Granular Odorless
    Peso molecular:299.66
  • AZ960

    CAS:
    <p>AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: &lt;3 nM and0.45 nM).</p>
    Fórmula:C18H16F2N6
    Pureza:96.02% - 98.51%
    Cor e Forma:Solid
    Peso molecular:354.36
  • AEE788

    CAS:
    <p>AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.</p>
    Fórmula:C27H32N6
    Pureza:98% - >99.99%
    Cor e Forma:Solid
    Peso molecular:440.58
  • 18α-Glycyrrhetinic acid

    CAS:
    <p>18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.</p>
    Fórmula:C30H46O4
    Pureza:98.54% - 99.68%
    Cor e Forma:Solid
    Peso molecular:470.68
  • Antineoplaston A10

    CAS:
    <p>Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.</p>
    Fórmula:C13H14N2O3
    Pureza:99.42%
    Cor e Forma:Solid
    Peso molecular:246.26
  • Valepotriate

    CAS:
    <p>Valepotriates are sedative, enhance memory, have anti-cancer properties, and may reduce anxiety.</p>
    Fórmula:C22H30O8
    Pureza:97.29% - 99.90%
    Cor e Forma:Solid
    Peso molecular:422.47
  • (E)-Flavokawain A

    CAS:
    <p>(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway.</p>
    Fórmula:C18H18O5
    Pureza:98% - 99.75%
    Cor e Forma:Solid
    Peso molecular:314.332
  • Atractylenolide III

    CAS:
    <p>Atractylenolide III could treat cognitive issues and lung cancer by modulating apoptosis factors.</p>
    Fórmula:C15H20O3
    Pureza:99.53% - 99.82%
    Cor e Forma:Solid
    Peso molecular:248.32
  • Oleuropein

    CAS:
    <p>Oleuropein is an antioxidant polyphenol isolated from olive leaf.</p>
    Fórmula:C25H32O13
    Pureza:98% - 99.95%
    Cor e Forma:Brown Powder
    Peso molecular:540.51
  • Columbianadin

    CAS:
    <p>Columbianadin (Zosimin), one of the main bioactive constituents of the roots of Angelica pubescens Maxim.</p>
    Fórmula:C19H20O5
    Pureza:98.44% - 99.48%
    Cor e Forma:Solid
    Peso molecular:328.36
  • Flavokawain C

    CAS:
    <p>Flavokawain C: natural chalcone from Kava with potential as a colon cancer drug.</p>
    Fórmula:C17H16O5
    Pureza:99.94% - ≥95%
    Cor e Forma:Solid
    Peso molecular:300.31
  • GSK2606414

    CAS:
    <p>GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase(PERK)inhibitor.Cost-effective and quality-assured.</p>
    Fórmula:C24H20F3N5O
    Pureza:98% - >99.99%
    Cor e Forma:Solid
    Peso molecular:451.44
  • PK11007

    CAS:
    <p>PK11007 is an anti-p53 drug.</p>
    Fórmula:C15H11ClFN5O3S2
    Pureza:97.55%
    Cor e Forma:Solid
    Peso molecular:427.86
  • Masitinib mesylate

    CAS:
    <p>Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;</p>
    Fórmula:C29H34N6O4S2
    Pureza:97.67% - 98.44%
    Cor e Forma:Solid
    Peso molecular:594.75
  • Sulforaphene

    CAS:
    <p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>
    Fórmula:C6H9NOS2
    Pureza:97.55% - 99.19%
    Cor e Forma:Slightly Yellowish Liquid
    Peso molecular:175.27
  • Didanosine

    CAS:
    <p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>
    Fórmula:C10H12N4O3
    Pureza:99.64%
    Cor e Forma:White Crystalline Powder
    Peso molecular:236.23
  • Neogambogic acid

    CAS:
    <p>Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect.</p>
    Fórmula:C38H46O9
    Pureza:97.74% - 99.38%
    Cor e Forma:Solid
    Peso molecular:646.77
  • SB 415286

    CAS:
    <p>SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.</p>
    Fórmula:C16H10ClN3O5
    Pureza:99.55%
    Cor e Forma:Solid
    Peso molecular:359.72
  • SR-4835

    CAS:
    <p>SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13(CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM), which disables triple-negative breast cancer (</p>
    Fórmula:C21H20Cl2N10O
    Pureza:98.09% - >99.99%
    Cor e Forma:Solid
    Peso molecular:499.36
  • Indirubin

    CAS:
    <p>Indirubin (Couroupitine B) is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.</p>
    Fórmula:C16H10N2O2
    Pureza:97.21% - 99.74%
    Cor e Forma:Reddish-Violet Powder
    Peso molecular:262.26
  • UC2288

    CAS:
    <p>UC2288, a Sorafenib-based p21 attenuator, reduces p21 levels without affecting its stability.</p>
    Fórmula:C20H18ClF6N3O2
    Pureza:99.75%
    Cor e Forma:Solid
    Peso molecular:481.82
  • dBET6

    CAS:
    <p>dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.</p>
    Fórmula:C42H45ClN8O7S
    Pureza:97.57% - 99.12%
    Cor e Forma:Solid
    Peso molecular:841.37
  • Carnosic acid

    CAS:
    <p>Carnosic acid is a lipid absorption inhibitor, endowed with antioxidative, antimicrobial, photoprotective potential, and antiproliferative properties.</p>
    Fórmula:C20H28O4
    Pureza:98.31% - 99.5%
    Cor e Forma:Yellow Powder
    Peso molecular:332.43
  • MG-132

    CAS:
    <p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>
    Fórmula:C26H41N3O5
    Pureza:95% - 99.99%
    Cor e Forma:White To Off-White Powder
    Peso molecular:475.62
  • Taurodeoxycholic acid sodium hydrate

    CAS:
    <p>Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.</p>
    Fórmula:C26H46NNaO7S
    Pureza:99.95%
    Cor e Forma:Solid
    Peso molecular:539.70
  • Triglycidyl isocyanurate

    CAS:
    <p>Triglycidyl isocyanurate (Teroxirone) is a cancer-research chemical with DNA-altering properties, also used in metal finishing.</p>
    Fórmula:C12H15N3O6
    Pureza:99.01%
    Cor e Forma:White Solid Particulates
    Peso molecular:297.26
  • GSK4112

    CAS:
    <p>GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.</p>
    Fórmula:C18H21ClN2O4S
    Pureza:99.69%
    Cor e Forma:Solid
    Peso molecular:396.89
  • CCF642

    CAS:
    <p>CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.</p>
    Fórmula:C15H10N2O4S3
    Pureza:97.12% - 98.82%
    Cor e Forma:Solid
    Peso molecular:378.45
  • PFI-90

    CAS:
    <p>PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity.</p>
    Fórmula:C11H10N4O
    Pureza:99.46%
    Cor e Forma:Solid
    Peso molecular:214.22
  • Triptonide

    CAS:
    <p>Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.</p>
    Fórmula:C20H22O6
    Pureza:99.11% - 99.64%
    Cor e Forma:White Crystalline Powder
    Peso molecular:358.39
  • Nelarabine

    CAS:
    <p>Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.</p>
    Fórmula:C11H15N5O5
    Pureza:98.10% - 99.6%
    Cor e Forma:White Solid
    Peso molecular:297.27
  • Abacavir sulfate

    CAS:
    <p>Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity</p>
    Fórmula:C14H18N6OH2O4S
    Pureza:99.79% - 99.85%
    Cor e Forma:White To Off-White Solid
    Peso molecular:335.38
  • Prucalopride Succinate

    CAS:
    <p>Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).</p>
    Fórmula:C18H26ClN3O3·C4H6O4
    Pureza:99.24%
    Cor e Forma:Solid
    Peso molecular:485.96
  • Bromosporine

    CAS:
    <p>Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.</p>
    Fórmula:C17H20N6O4S
    Pureza:99.65% - 99.79%
    Cor e Forma:Solid
    Peso molecular:404.44
  • Hispidol

    CAS:
    <p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>
    Fórmula:C15H10O4
    Pureza:97.86% - 98.45%
    Cor e Forma:Solid
    Peso molecular:254.24
  • 4-Methyldaphnetin

    CAS:
    <p>4-Methyldaphnetin (DHMC) is a potent inhibitor of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals.</p>
    Fórmula:C10H8O4
    Pureza:99.73%
    Cor e Forma:Solid
    Peso molecular:192.17
  • Brevilin A

    CAS:
    <p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>
    Fórmula:C20H26O5
    Pureza:99.97% - >99.99%
    Cor e Forma:Solid
    Peso molecular:346.42
  • Methotrexate disodium

    CAS:
    <p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>
    Fórmula:C20H20N8Na2O5
    Pureza:99.77% - 99.96%
    Cor e Forma:Solid
    Peso molecular:498.4
  • Actein

    CAS:
    <p>Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.</p>
    Fórmula:C37H56O11
    Pureza:≥98%
    Cor e Forma:Brown Powder
    Peso molecular:676.83
  • UCF 101

    CAS:
    <p>UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.</p>
    Fórmula:C27H17N3O5S
    Pureza:99.64%
    Cor e Forma:Solid
    Peso molecular:495.51
  • Gomisin N

    CAS:
    <p>Gomisin N from Schisandra chinensis offers sedative effects, allergy relief, and cancer cell inhibition/apoptosis.</p>
    Fórmula:C23H28O6
    Pureza:99.97% - >99.99%
    Cor e Forma:Solid
    Peso molecular:400.46
  • PHYTOSPHINGOSINE

    CAS:
    <p>Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.</p>
    Fórmula:C18H39NO3
    Pureza:99.81%
    Cor e Forma:Solid
    Peso molecular:317.51
  • AZD-7648

    CAS:
    <p>AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.</p>
    Fórmula:C18H20N8O2
    Pureza:99.03% - 99.85%
    Cor e Forma:Solid
    Peso molecular:380.4
  • Verbascoside

    CAS:
    <p>Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.</p>
    Fórmula:C29H36O15
    Pureza:97.46% - 99.55%
    Cor e Forma:Solid
    Peso molecular:624.59