Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5598 produtos de "Apoptose"
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Lupeol
CAS:<p>Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.</p>Fórmula:C30H50OPureza:98% - 99.96%Cor e Forma:Needles From Alcohol Acetone White PowderPeso molecular:426.72Purvalanol A
CAS:<p>Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.</p>Fórmula:C19H25ClN6OPureza:98.13% - 99.68%Cor e Forma:PowderPeso molecular:388.89Meisoindigo
CAS:<p>Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).</p>Fórmula:C17H12N2O2Pureza:98.03% - 98.19%Cor e Forma:SolidPeso molecular:276.29Pinosylvin
CAS:<p>Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.</p>Fórmula:C14H12O2Pureza:99.89% - 99.91%Cor e Forma:SolidPeso molecular:212.24M50054
CAS:<p>Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.</p>Fórmula:C13H16O4Pureza:97.8%Cor e Forma:SolidPeso molecular:236.26BI-847325
CAS:<p>BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.</p>Fórmula:C29H28N4O2Pureza:97.13% - 97.54%Cor e Forma:SolidPeso molecular:464.56BI 2536
CAS:<p>BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.</p>Fórmula:C28H39N7O3Pureza:98% - 99.88%Cor e Forma:SolidPeso molecular:521.65Copanlisib
CAS:<p>Copanlisib (BAY 80-6946), a PI3K inhibitor, may block tumor growth and improve cancer treatment efficacy.</p>Fórmula:C23H28N8O4Pureza:99% - 99.88%Cor e Forma:SolidPeso molecular:480.52Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Fórmula:C20H18O11Pureza:97.02% - 99.94%Cor e Forma:White PowderPeso molecular:434.35PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Fórmula:C15H11NSPureza:98.00%Cor e Forma:SolidPeso molecular:237.32Terrestrosin D
CAS:<p>Terrestrosin D triggers apoptosis, halts cell cycles, and blocks angiogenesis in tumor cells, displaying anti-cancer effects.</p>Fórmula:C50H80O23Pureza:99.92% - 99.96%Cor e Forma:SolidPeso molecular:1049.16Ganetespib
CAS:<p>Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.</p>Fórmula:C20H20N4O3Pureza:98% - 99.95%Cor e Forma:SolidPeso molecular:364.4Aminopurvalanol A
CAS:<p>Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1</p>Fórmula:C19H26ClN7OPureza:99.73%Cor e Forma:SolidPeso molecular:403.91Apomine
CAS:<p>Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂，可在体外促进骨髓瘤细胞的凋亡，并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。</p>Fórmula:C28H52O7P2Pureza:>99.99%Cor e Forma:SolidPeso molecular:562.66TBHQ
CAS:<p>TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.</p>Fórmula:C10H14O2Pureza:99.17% - 99.53%Cor e Forma:White Solid PowderPeso molecular:166.22Ginsenoside Rh2
CAS:<p>Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.</p>Fórmula:C36H62O8Pureza:99.20% - 99.76%Cor e Forma:White PowderPeso molecular:622.87Ginsenoside F2
CAS:<p>Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.</p>Fórmula:C42H72O13Pureza:99.04% - 99.3%Cor e Forma:SolidPeso molecular:785.01HA14-1
CAS:<p>HA14-1, a Bcl-2/Bcl-XL antagonist, is a non-peptidic ligand of a Bcl-2 surface pocket (IC50: ~9 μM).</p>Fórmula:C17H17BrN2O5Pureza:95.07% - 98%Cor e Forma:SolidPeso molecular:409.23LCL161
CAS:<p>LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C26H33FN4O3SPureza:99.13% - 99.87%Cor e Forma:SolidPeso molecular:500.63Mocetinostat
CAS:<p>Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.</p>Fórmula:C23H20N6OPureza:99% - 99.21%Cor e Forma:SolidPeso molecular:396.44AG1024
CAS:<p>AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).</p>Fórmula:C14H13BrN2OPureza:98% - 99.37%Cor e Forma:SolidPeso molecular:305.17Sertaconazole
CAS:<p>Sertaconazole is a broad-spectrum antifungal.</p>Fórmula:C20H15Cl3N2OSPureza:99.483%Cor e Forma:SolidPeso molecular:437.77Rigosertib
CAS:<p>Rigosertib, a multi-kinase inhibitor targeting PLK1 (IC50: 9 nM), induces apoptosis and G2/M arrest by disrupting PI3K/Akt.</p>Fórmula:C21H25NO8SPureza:99.53%Cor e Forma:SolidPeso molecular:451.49PI-103
CAS:<p>PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).</p>Fórmula:C19H16N4O3Pureza:97.79% - 99.3%Cor e Forma:SolidPeso molecular:348.36ML311
CAS:<p>ML311 is a selective inhibitor of the Mcl-1/Bim interaction.</p>Fórmula:C23H24F3N3OPureza:99.75%Cor e Forma:SolidPeso molecular:415.45Asiaticoside
CAS:<p>Asiaticoside, in Centella asiatica, may treat wounds/burns.</p>Fórmula:C48H78O19Pureza:98% - 99.96%Cor e Forma:PowderPeso molecular:959.12SC66
CAS:<p>SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 μg/ml, at 72 h).</p>Fórmula:C18H16N2OPureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:276.33Rhosin hydrochloride
CAS:<p>Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.</p>Fórmula:C20H20Cl2N6OPureza:97.33% - 98.92%Cor e Forma:SolidPeso molecular:431.318NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Fórmula:C45H82N11O17P3Pureza:98.73% - 99.05%Cor e Forma:SolidPeso molecular:1142.12Idasanutlin
CAS:<p>Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).</p>Fórmula:C31H29Cl2F2N3O4Pureza:99.13% - 99.88%Cor e Forma:SolidPeso molecular:616.48CPTH2
CAS:<p>CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.</p>Fórmula:C14H14ClN3SPureza:99.81%Cor e Forma:SolidPeso molecular:291.8ZMC1
CAS:<p>NSC-319726 (ZMC1), a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM).</p>Fórmula:C11H14N4SPureza:98.97% - 99.76%Cor e Forma:SolidPeso molecular:234.32RAD51 Inhibitor B02
CAS:<p>RAD51 Inhibitor B02 (B02) (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.</p>Fórmula:C22H17N3OPureza:99.72% - 99.89%Cor e Forma:SolidPeso molecular:339.39Bendamustine
CAS:<p>Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia</p>Fórmula:C16H21Cl2N3O2Pureza:≥98%Cor e Forma:SolidPeso molecular:358.26Sertaconazole nitrate
CAS:<p>Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.</p>Fórmula:C20H15Cl3N2OS·HNO3Pureza:98.66% - 99.65%Cor e Forma:SolidPeso molecular:500.78Almorexant
CAS:<p>Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.</p>Fórmula:C29H31F3N2O3Pureza:97.75% - 98.02%Cor e Forma:SolidPeso molecular:512.56Grape Seed Extract
CAS:<p>Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites.</p>Fórmula:C32H30O11Pureza:98%Cor e Forma:SolidPeso molecular:590.581CVT-11127
CAS:<p>CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.</p>Fórmula:C25H23Cl2N5O3Pureza:98.32%Cor e Forma:SolidPeso molecular:512.39N-Ethylmaleimide
CAS:<p>N-Ethylmaleimide (NEM) is a reagent for alkylation of free sulfhydryl groups, a cysteine protease inhibitor. Cost-effective and quality-assured.</p>Fórmula:C6H7NO2Pureza:99.50%Cor e Forma:White SolidPeso molecular:125.13Cucurbitacin IIA
CAS:<p>1.</p>Fórmula:C32H50O8Pureza:98.62% - 99.87%Cor e Forma:SolidPeso molecular:562.73OSI-930
CAS:<p>OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.</p>Fórmula:C22H16F3N3O2SPureza:99.67%Cor e Forma:SolidPeso molecular:443.44Tanespimycin
CAS:<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Fórmula:C31H43N3O8Pureza:99.07% - 99.83%Cor e Forma:Dark Purple SolidPeso molecular:585.692-tert-Butyl-1,4-benzoquinone
CAS:<p>TBQ, a BHA metabolite, activates Nrf2 and S-arylates Keap1 in RAW264.7 cells.</p>Fórmula:C10H12O2Pureza:97.19%Cor e Forma:SolidPeso molecular:164.2Quizartinib
CAS:<p>Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.</p>Fórmula:C29H32N6O4SPureza:98% - 99.42%Cor e Forma:SolidPeso molecular:560.67Caudatin
CAS:<p>Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.</p>Fórmula:C28H42O7Pureza:98.83% - 99.9%Cor e Forma:SolidPeso molecular:490.63Taurochenodeoxycholic acid sodium
CAS:<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Fórmula:C26H44NNaO6SPureza:98.23% - 99.45%Cor e Forma:White To Off-White PowderPeso molecular:521.68GSK-J4
CAS:<p>GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.</p>Fórmula:C24H27N5O2Pureza:98.24% - 99.98%Cor e Forma:SolidPeso molecular:417.5Angelicin
CAS:<p>Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.</p>Fórmula:C11H6O3Pureza:99.86% - 99.89%Cor e Forma:White SolidPeso molecular:186.16Fimasartan
CAS:<p>Fimasartan (BR-A-657), an ARB, treats hypertension and heart failure; safe with hydrochlorothiazide.</p>Fórmula:C27H31N7OSPureza:98.96%Cor e Forma:SolidPeso molecular:501.65Lenalidomide hemihydrate
CAS:<p>Lenalidomide hemihydrate inhibits TNF-α (IC50=13nM) and binds CRBN/DDB1 complexes.</p>Fórmula:C13H13N3O3H2OPureza:96.22%Cor e Forma:SolidPeso molecular:268.28
