Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Concanavalin A
CAS:<p>Concanavalin A is a natural product, a phytoalexin. Concanavalin A has antitumor activity and can also induce acute liver injury. Cost effective and quality assured.</p>Fórmula:C23H32N6O8SPureza:98%Cor e Forma:SolidPeso molecular:104-112 kDaSBI-0206965
CAS:<p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>Fórmula:C21H21BrN4O5Pureza:99.13%Cor e Forma:SolidPeso molecular:489.32Thalidomide 4-fluoride
CAS:<p>Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand.</p>Fórmula:C13H9FN2O4Pureza:99.12%Cor e Forma:SolidPeso molecular:276.22Capsazepine
CAS:<p>Capsazepine, a TRPV1 antagonist (IC50: 562 nM), blocks capsaicin-induced heat pain.</p>Fórmula:C19H21ClN2O2SPureza:98% - 99.78%Cor e Forma:White To Off-White PowderPeso molecular:376.9Tandutinib
CAS:<p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>Fórmula:C31H42N6O4Pureza:99.45% - ≥98%Cor e Forma:White SolidPeso molecular:562.7D4476
CAS:<p>D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).</p>Fórmula:C23H18N4O3Pureza:99.7% - 99.96%Cor e Forma:SolidPeso molecular:398.41Thalidomide-O-amido-C6-NH2 hydrochloride
CAS:<p>Thalidomide-O-amido-C6-NH2 HCl, a cereblon ligand-linker for PROTAC synthesis.</p>Fórmula:C21H27ClN4O6Pureza:97.33%Cor e Forma:SolidPeso molecular:466.915Fimepinostat
CAS:<p>Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both PI3K class I and pan-HDAC enzymes, with potential antineoplastic activity.</p>Fórmula:C23H24N8O4SPureza:98.27% - 99.87%Cor e Forma:SolidPeso molecular:508.55CA-4948
CAS:<p>CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.</p>Fórmula:C24H25N7O5Pureza:99.35% - 99.88%Cor e Forma:SolidPeso molecular:491.5Tenovin-6
CAS:<p>Tenovin-6 is a p53 transcriptional activity agonist.</p>Fórmula:C25H34N4O2SPureza:97.71% - >99.99%Cor e Forma:SolidPeso molecular:454.63PHA-665752
CAS:<p>PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.</p>Fórmula:C32H34Cl2N4O4SPureza:97.05% - 98.82%Cor e Forma:SolidPeso molecular:641.61Dacarbazine citrate
CAS:<p>Dacarbazine citrate treats lymphatic cancers, malignant melanoma, islet cell carcinoma, and soft tissue sarcoma.</p>Fórmula:C12H18N6O8Cor e Forma:SolidPeso molecular:374.31Isolongifolene
CAS:<p>Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, and</p>Fórmula:C15H24Pureza:90.13% - 99.46%Cor e Forma:Colorless Or Light Yellow LiquidPeso molecular:204.35ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Fórmula:C30H30F3N5OPureza:99.30%Cor e Forma:SolidPeso molecular:533.59Dipyrithione
CAS:<p>Dipyrithione appears to have novel cytotoxicity and potent broad-spectrum antitumor activity</p>Fórmula:C10H8N2O2S2Pureza:99.9%Cor e Forma:Beige Crystalline PowderPeso molecular:252.31ERK1/2 inhibitor 2
CAS:<p>ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable ERK 1/2 inhibitor, with potential antineoplastic activity.</p>Fórmula:C29H31ClFN5O5Pureza:98.99%Cor e Forma:SolidPeso molecular:584.04Thalidomide-NH-CH2-COOH TFA
CAS:<p>2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}acetic acid (trifluoroacetic acid) is mainly used in compounds Synthesis.</p>Fórmula:C17H14F3N3O8Pureza:95.00%Cor e Forma:SolidPeso molecular:445.3036L67
CAS:<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Fórmula:C16H14Br2N4O4Pureza:98.34% - 99.56%Cor e Forma:SolidPeso molecular:486.11Phenoxodiol
CAS:<p>Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)</p>Fórmula:C15H12O3Pureza:98.07%Cor e Forma:SolidPeso molecular:240.25Trifloxystrobin
CAS:<p>Trifloxystrobin is a fungicide against R. solani in sugar beets with EC50s: 23.0 μg/L for Daphnia neonates, 1.7 μg/L for embryos.</p>Fórmula:C20H19F3N2O4Pureza:99.49%Cor e Forma:SolidPeso molecular:408.37Anisomycin
CAS:<p>Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.</p>Fórmula:C14H19NO4Pureza:98.33% - 99.81%Cor e Forma:White Crystalline SolidPeso molecular:265.3KYP-2047
CAS:<p>KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.</p>Fórmula:C20H25N3O2Pureza:99.71%Cor e Forma:SolidPeso molecular:339.43LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Fórmula:C19H17NO3Pureza:98% - 99.96%Cor e Forma:Pale Yellow SolidPeso molecular:307.34JKE-1674
CAS:<p>JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.</p>Fórmula:C20H20Cl2N4O4Pureza:98.02% - 98.4%Cor e Forma:SolidPeso molecular:451.3QNZ
CAS:<p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>Fórmula:C22H20N4OPureza:99.17% - 99.18%Cor e Forma:White SolidPeso molecular:356.42Cannabigerol
CAS:<p>Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also</p>Fórmula:C21H32O2Pureza:99.59% - 99.92%Cor e Forma:SolidPeso molecular:316.48Geranyl acetate
CAS:<p>Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.</p>Fórmula:C12H20O2Pureza:98% - 99.36%Cor e Forma:Physical Description Clear Colorless Liquid With An Odor Of Lavender (Ntp 1992)Peso molecular:196.29Bardoxolone
CAS:<p>Bardoxolone (CDDO) inhibits iNOS, COX-2 in cells; IC50=0.4nM. Reduces ROS/RNS, DNA damage, & cancer growth; triggers apoptosis & boosts antioxidant genes.</p>Fórmula:C31H41NO4Pureza:97.9% - 98.97%Cor e Forma:SolidPeso molecular:491.66Thalidomide-O-C4-NH2 hydrochloride
CAS:<p>Thalidomide-linker 9: a cereblon ligand, E3 ligase conjugate for PROTAC tech.</p>Fórmula:C17H20ClN3O5Pureza:98.33%Cor e Forma:SolidPeso molecular:381.81Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis-
CAS:<p>Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI) is an inhibitor of p53 with an IC50 value of 0.35 μM</p>Fórmula:C22H16N2OPureza:99.18%Cor e Forma:SolidPeso molecular:324.38Dihydrocapsaicin
CAS:<p>Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.</p>Fórmula:C18H29NO3Pureza:99.61% - ≥95%Cor e Forma:White CrystalPeso molecular:307.43(Z)-Mirin
CAS:<p>(Z)-Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.</p>Fórmula:C10H8N2O2SPureza:99.67% - 99.76%Cor e Forma:SolidPeso molecular:220.253,4 Dichloroisocoumarin
CAS:<p>3,4 Dichloroisocoumarin is a granzyme, cathepsin G, and neutrolphil elastase inhibitor</p>Fórmula:C9H4Cl2O2Pureza:97.94%Cor e Forma:SolidPeso molecular:215.03Laquinimod sodium
CAS:<p>Laquinimod (ABR-215062) sodium is an oral agent for MS, halting neurodegeneration and inflammation.</p>Fórmula:C19H16ClN2NaO3Cor e Forma:SolidPeso molecular:378.79Semaglutide
CAS:<p>Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor).</p>Fórmula:C187H291N45O59Pureza:96.92% - 99.78%Cor e Forma:SolidPeso molecular:4114PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Fórmula:C15H11NSPureza:98.00%Cor e Forma:SolidPeso molecular:237.32Terrestrosin D
CAS:<p>Terrestrosin D triggers apoptosis, halts cell cycles, and blocks angiogenesis in tumor cells, displaying anti-cancer effects.</p>Fórmula:C50H80O23Pureza:99.92% - 99.96%Cor e Forma:SolidPeso molecular:1049.16Trabectedin
CAS:<p>Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.</p>Fórmula:C39H43N3O11SPureza:≥98%Cor e Forma:SolidPeso molecular:761.84ARS-853
CAS:<p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>Fórmula:C22H29ClN4O3Pureza:97.43% - 98.4%Cor e Forma:SolidPeso molecular:432.94CRT0066101 dihydrochloride
CAS:<p>CRT0066101 dihydrochloride is an effective and selective PKD inhibitor (IC50s: 1, 2.5 and 2 nM for PKD1, 2, and 3).</p>Fórmula:C18H22N6O·2HClPureza:99.85%Cor e Forma:SolidPeso molecular:411.33Eriocitrin
CAS:<p>Eriocitrin: an antioxidative flavonoid; reduces exercise-induced oxidative damage and lipids; fights fatty liver and inhibits carbonic anhydrase VA.</p>Fórmula:C27H32O15Pureza:98.41% - 99.11%Cor e Forma:SolidPeso molecular:596.533BDO
CAS:<p>3BDO is a new mTOR activator. 3BDO inhibits autophagy.</p>Fórmula:C18H17NO5Pureza:97.76%Cor e Forma:SolidPeso molecular:327.33PR-619
CAS:<p>PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.</p>Fórmula:C7H5N5S2Pureza:97.25% - >99.99%Cor e Forma:SolidPeso molecular:223.28Ganetespib
CAS:<p>Ganetespib (STA-9090) is a synthetic small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity.</p>Fórmula:C20H20N4O3Pureza:98% - 99.95%Cor e Forma:SolidPeso molecular:364.4Artemisitene
CAS:<p>Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.</p>Fórmula:C15H20O5Pureza:99.58%Cor e Forma:SolidPeso molecular:280.32BAM7
CAS:<p>BAM 7 is a direct and specific activator of proapoptotic Bax (EC50: 3.3 μM).</p>Fórmula:C21H19N5O2SPureza:98.51% - 98.68%Cor e Forma:SolidPeso molecular:405.47EPZ004777 hydrochloride
CAS:<p>EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.</p>Fórmula:C28H42ClN7O4Cor e Forma:SolidPeso molecular:576.13Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Fórmula:C23H22ClNO2Pureza:99.25%Cor e Forma:Yellowish SolidPeso molecular:379.88DB1976 dihydrochloride
CAS:<p>DB1976 dihydrochloride (DB1976 2HCl), a transcription factor PU.1 inhibitor, has potential anti-inflammatory activity for the study of metabolic dysfunction.</p>Fórmula:C20H18Cl2N8SePureza:99.08%Cor e Forma:SolidPeso molecular:520.28Thalidomide-O-C6-NH2 hydrochloride
CAS:<p>Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) is a synthesized E3 ligase ligand-</p>Fórmula:C19H24ClN3O5Pureza:97.45%Cor e Forma:SolidPeso molecular:409.86
![Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT9129.webp&w=3840&q=75)
