Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5598 produtos de "Apoptose"
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Acenocoumarol
CAS:<p>Acenocoumarol is a Vitamin K antagonist and used as an anticoagulant.</p>Fórmula:C19H15NO6Pureza:99.95%Cor e Forma:Crystals SolidPeso molecular:353.33Sinapinic Acid
CAS:<p>Sinapinic Acid (Synapoic acid) is a phenolic isolated from the roots of Hydnophytum formicarumJack. It is an HDAC inhibitor and also inhibits ACE-I activity.</p>Fórmula:C11H12O5Pureza:99.88% - >99.99%Cor e Forma:SolidPeso molecular:224.21PD184161
CAS:<p>PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].</p>Fórmula:C17H13BrClF2IN2O2Pureza:99.40%Cor e Forma:SolidPeso molecular:557.56Rhapontin
CAS:<p>Rhapontin may reduce liver fat and better blood sugar/lipids, showing potential for treating type 2 diabetes.</p>Fórmula:C21H24O9Pureza:99% - 99.91%Cor e Forma:Light YellowPeso molecular:420.41Perillyl alcohol
CAS:<p>Perillyl Alcohol, a monoterpene with antitumor properties, inhibits protein activation blocking cancer cell growth.</p>Fórmula:C10H16OPureza:97.36%Cor e Forma:SolidPeso molecular:152.23Licochalcone B
CAS:<p>Licochalcone B inhibits human bladder cancer cells, reduces inflammation by NO, TNFalpha, and MCP-1, and a derivative protects against endotoxin shock.</p>Fórmula:C16H14O5Pureza:99.33% - 99.93%Cor e Forma:SolidPeso molecular:286.28ZM 336372
CAS:<p>ZM 336372 is a potent and selective c-Raf inhibitor.</p>Fórmula:C23H23N3O3Pureza:97.24% - 97.51%Cor e Forma:SolidPeso molecular:389.45Notoginsenoside R1
CAS:<p>Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.</p>Fórmula:C47H80O18Pureza:99.57% - >99.99%Cor e Forma:SolidPeso molecular:933.13Geranylgeraniol
CAS:<p>Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.</p>Fórmula:C20H34OPureza:99.17% - ≥98%Cor e Forma:SolidPeso molecular:290.48Avelumab
CAS:<p>Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.</p>Pureza:95% - 97.17% (SDS-PAGE)Cor e Forma:LiquidPeso molecular:143.8 kDaNS-1619
CAS:<p>NS1619 have cardio-protective effects after ischemia-reperfusion injury.</p>Fórmula:C15H8F6N2O2Pureza:97.66% - 98%Cor e Forma:SolidPeso molecular:362.23SSE15206
CAS:<p>SSE15206 is a microtubule polymerization inhibitor that overcomes multidrug resistance.</p>Fórmula:C19H21N3O3SPureza:98.81%Cor e Forma:SolidPeso molecular:371.45Ac-DEVD-CHO acetate
<p>Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.</p>Fórmula:C22H34N4O13Pureza:98.54%Cor e Forma:SolidPeso molecular:562.52Niraparib tosylate
CAS:<p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>Fórmula:C19H20N4O·C7H8O3SPureza:99.34% - 99.87%Cor e Forma:SolidPeso molecular:492.59Tenovin-1
CAS:<p>Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.</p>Fórmula:C20H23N3O2SPureza:99.33%Cor e Forma:SolidPeso molecular:369.48Cyclovirobuxine D
CAS:<p>Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.</p>Fórmula:C26H46N2OPureza:97.78% - 98%Cor e Forma:SolidPeso molecular:402.66AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Fórmula:C21H21N3O2SPureza:97.24% - 99.83%Cor e Forma:SolidPeso molecular:379.48Tubastatin A Hydrochloride
CAS:<p>Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).</p>Fórmula:C20H21N3O2·HClPureza:97.24% - 99.15%Cor e Forma:SolidPeso molecular:371.86Ganoderenic acid D
CAS:<p>Ganoderenic acid D, extracted from Ganoderma lucidum, triggers apoptosis and halts cancer cell growth.</p>Fórmula:C30H40O7Pureza:99.05%Cor e Forma:SolidPeso molecular:512.63Navitoclax
CAS:<p>View and buy Navitoclax from TargetMol.Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2.Cited in 4 publications.</p>Fórmula:C47H55ClF3N5O6S3Pureza:95.82% - >99.99%Cor e Forma:Pale Yellow SolidPeso molecular:974.61Tivantinib
CAS:<p>Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.</p>Fórmula:C23H19N3O2Pureza:98% - 99.41%Cor e Forma:SolidPeso molecular:369.42Dihydrokaempferol
CAS:<p>Dihydrokaempferol (Aromadendrin) is a natural product. It induces apoptosis and inhibits Bcl-2 and Bcl-xL expression, possesses anti-inflammatory activity.</p>Fórmula:C15H12O6Pureza:97.79% - 99.96%Cor e Forma:SolidPeso molecular:288.25Prexasertib
CAS:<p>Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM). antitumor activity. High-Quality, Low-Cost!</p>Fórmula:C18H19N7O2Pureza:97.3% - 98.23%Cor e Forma:SolidPeso molecular:365.39SC-236
CAS:<p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>Fórmula:C16H11ClF3N3O2SPureza:99.74%Cor e Forma:SolidPeso molecular:401.79SNS-032
CAS:<p>SNS-032 (BMS-387032) is a selective inhibitor of CDK2 and is 10- and 20-fold selective over CDK1/CDK4. SNS-032 is sensitive to CDK7/9, and no effect on CDK6.</p>Fórmula:C17H24N4O2S2Pureza:98.27% - 99.91%Cor e Forma:SolidPeso molecular:380.53Fulvestrant
CAS:<p>Fulvestrant (ZM 182780) is an estrogen receptor (ER) antagonist (IC50=9.4 nM) and an agonist of GPR30.</p>Fórmula:C32H47F5O3SPureza:99.1% - >99.99%Cor e Forma:White PowderPeso molecular:606.77NPS-1034
CAS:<p>NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.</p>Fórmula:C31H23F2N5O3Pureza:98.48%Cor e Forma:SolidPeso molecular:551.54SecinH3
CAS:<p>SecinH3 is selective cytohesin inhibitor.</p>Fórmula:C24H20N4O4SPureza:97.49% - 99.37%Cor e Forma:SolidPeso molecular:460.51EB-3D
CAS:<p>EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.</p>Fórmula:C30H36Br2N4O2Pureza:99.48%Cor e Forma:SolidPeso molecular:644.4NVP-CGM097
CAS:<p>NVP-CGM097 (CGM097) is an effective and specific MDM2 inhibitor (IC50: 1.7 nM for hMDM2).</p>Fórmula:C38H47ClN4O4Pureza:98.77%Cor e Forma:SolidPeso molecular:659.26NVP-TNKS656
CAS:<p>NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.</p>Fórmula:C27H34N4O5Pureza:99.59%Cor e Forma:SolidPeso molecular:494.58Amifostine thiol dihydrochloride
CAS:<p>Amifostine (WR 1065) activates p53 via JNK and shields tissues from cancer drug toxicity.</p>Fórmula:C5H16Cl2N2SPureza:>99.99%Cor e Forma:SolidPeso molecular:207.165Coniferaldehyde
CAS:<p>Coniferaldehyde (Ferulaldehyde) is a member of the class of cinnamaldehydes. Coniferaldehyde has a role as an antifungal agent and a plant metabolite.</p>Fórmula:C10H10O3Pureza:96.35% - 99.96%Cor e Forma:SolidPeso molecular:178.18LDC000067
CAS:<p>LDC000067 (LDC067) is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 nM.</p>Fórmula:C18H18N4O3SPureza:98.08% - 99.07%Cor e Forma:SolidPeso molecular:370.43Cobimetinib
CAS:<p>Cobimetinib (GDC-0973) is a MEK1 inhibitor with selective and oral activity. Cobimetinib exhibits antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C21H21F3IN3O2Pureza:98% - 99.61%Cor e Forma:SolidPeso molecular:531.31GW 5074
CAS:<p>GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor.</p>Fórmula:C15H8Br2INO2Pureza:99.32%Cor e Forma:SolidPeso molecular:520.94TAK-243
CAS:<p>TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).</p>Fórmula:C19H20F3N5O5S2Pureza:98.09% - 98.93%Cor e Forma:SolidPeso molecular:519.52Didymin
CAS:<p>Didymin, an antioxidant, may treat neuroblastoma and neurodegeneration by blocking N-Myc and boosting RKIP.</p>Fórmula:C28H34O14Pureza:99.12% - 99.87%Cor e Forma:Faintly Beige PowderPeso molecular:594.56GSK2256098
CAS:<p>GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor.</p>Fórmula:C20H23ClN6O2Pureza:99.46% - 99.74%Cor e Forma:SolidPeso molecular:414.893,6-Dihydroxyflavone
CAS:<p>3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.</p>Fórmula:C15H10O4Pureza:99.92%Cor e Forma:SolidPeso molecular:254.24Oroxin B
CAS:<p>Oroxin B (Hypocretin-2) has antioxidant activity.</p>Fórmula:C27H30O15Pureza:98.22% - 99.81%Cor e Forma:SolidPeso molecular:594.52Thonningianin A
CAS:<p>Thonningianin A: an anti-cancer compound with antioxidant effects, GST inhibitor, and radical scavenger.</p>Fórmula:C42H34O21Pureza:98.37% - 99.94%Cor e Forma:SolidPeso molecular:874.71CDDO-Im
CAS:<p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>Fórmula:C34H43N3O3Pureza:98.3% - 99.61%Cor e Forma:SolidPeso molecular:541.72KEA1-97
CAS:<p>Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M).</p>Fórmula:C15H9Cl2FN4Pureza:97.07%Cor e Forma:SolidPeso molecular:335.16Vistusertib
CAS:<p>Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.</p>Fórmula:C25H30N6O3Pureza:97.08% - 99.06%Cor e Forma:SolidPeso molecular:462.54NADPH tetrasodium salt
CAS:<p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>Fórmula:C21H26N7Na4O17P3Pureza:97.15% - >99.99%Cor e Forma:SolidPeso molecular:833.35XL019
CAS:<p>XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.</p>Fórmula:C25H28N6O2Pureza:99.19%Cor e Forma:SolidPeso molecular:444.53CP-31398 dihydrochloride
CAS:<p>CP-31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines.</p>Fórmula:C22H28Cl2N4OPureza:98.23%Cor e Forma:SolidPeso molecular:435.4ABT-737
CAS:<p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>Fórmula:C42H45ClN6O5S2Pureza:98.15% - >99.99%Cor e Forma:SolidPeso molecular:813.43PF-4989216
CAS:<p>PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.</p>Fórmula:C18H13FN6OSPureza:99.85%Cor e Forma:SolidPeso molecular:380.4
