Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(134 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6222 produtos de "Apoptose"
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Desmethylanethol trithione
CAS:Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves recovery in mice.
Fórmula:C9H6OS3Pureza:98.05% - 98.41%Cor e Forma:SolidPeso molecular:226.34ONC212
CAS:ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.Fórmula:C24H23F3N4OPureza:99.79% - 99.98%Cor e Forma:SolidPeso molecular:440.46β-Ionone
CAS:β-Ionone (β-lonone) is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetables,with anti-proliferative, anti-metastaticFórmula:C13H20OPureza:98.52%Cor e Forma:Colourless Liquid OilyPeso molecular:192.3GS-444217
CAS:GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).Fórmula:C23H21N7OPureza:99.08%Cor e Forma:SolidPeso molecular:411.46OUL35
CAS:OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.Fórmula:C14H12N2O3Pureza:99.2%Cor e Forma:SolidPeso molecular:256.26TCPOBOP
CAS:TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly.Fórmula:C16H8Cl4N2O2Pureza:99.7%Cor e Forma:SolidPeso molecular:402.06B355252
CAS:B355252 prevents glutamate-induced cell death and boosts NGF's nerve growth effects.Fórmula:C25H24ClN3O3S2Pureza:98.73% - 99.92%Cor e Forma:SolidPeso molecular:514.06PD0166285
CAS:PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.Fórmula:C26H27Cl2N5O2Pureza:99.23%Cor e Forma:SolidPeso molecular:512.43AC1NS4RE
CAS:It is a tyrosine kinase inhibitor.Fórmula:C15H13ClN2OPureza:99.53%Cor e Forma:SolidPeso molecular:272.73Acacetin
CAS:Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidantFórmula:C16H12O5Pureza:96.26% - ≥95%Cor e Forma:Pale-Yellow NeedlesPeso molecular:284.26VK3-OCH3
CAS:VK3-OCH3 (2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na) is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.Fórmula:C14H14O3SPureza:99.71%Cor e Forma:SolidPeso molecular:262.32CAY10505
CAS:CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).Fórmula:C14H8FNO3SPureza:99.69% - 99.74%Cor e Forma:SolidPeso molecular:289.28Ref: TM-T6433
10mg34,00€1mL*10mM (DMSO)38,00€25mg52,00€50mg96,00€100mg144,00€200mg205,00€500mg350,00€MRS 2578
CAS:MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.Fórmula:C20H20N6S4Pureza:97.58% - 99.73%Cor e Forma:White SolidPeso molecular:472.67Polyphyllin I
CAS:Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Fórmula:C44H70O16Pureza:98% - 99.5%Cor e Forma:SolidPeso molecular:855.02Epothilone A
CAS:Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.Fórmula:C26H39NO6SPureza:99.89% - 99.92%Cor e Forma:SolidPeso molecular:493.66Fedratinib hydrochloride hydrate
CAS:Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.Fórmula:C27H40Cl2N6O4SPureza:98.96% - 99.87%Cor e Forma:SolidPeso molecular:615.61G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Fórmula:C22H19F2NO3Pureza:97.3%Cor e Forma:SolidPeso molecular:383.39Ref: TM-T8742
1mg35,00€5mg71,00€1mL*10mM (DMSO)78,00€10mg96,00€25mg172,00€50mg248,00€100mg348,00€200mg470,00€Alginic acid
CAS:Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.Fórmula:C14H22O13Pureza:≥98%Cor e Forma:SolidPeso molecular:398.317OTS514 hydrochloride
CAS:OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).Fórmula:C21H20N2O2S·HClPureza:99.67% - 99.84%Cor e Forma:SolidPeso molecular:400.92Ref: TM-T4134
1mg58,00€2mg92,00€5mg165,00€1mL*10mM (DMSO)165,00€10mg290,00€25mg527,00€50mg710,00€100mg898,00€500mg1.791,00€Kynurenic acid sodium
CAS:Kynurenic acid sodium salt is an endogenous tryptophan metabolite. It antagonizes NMDA, glutamate, and α7 nicotinic receptors, and agonizes GPR35.Fórmula:C10H6NNaO3Pureza:99.47%Cor e Forma:SolidPeso molecular:211.15MK-886
CAS:MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Fórmula:C27H34ClNO2SPureza:99.23% - 99.84%Cor e Forma:SolidPeso molecular:472.08Ref: TM-T6893
1mg34,00€5mg66,00€1mL*10mM (DMSO)69,00€10mg105,00€25mg205,00€50mg334,00€100mg512,00€200mg732,00€Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Fórmula:C15H18O3Pureza:98.48% - 99.96%Cor e Forma:SolidPeso molecular:246.3CASIN
CAS:CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Fórmula:C20H22N2OPureza:98.18% - >99.99%Cor e Forma:SolidPeso molecular:306.4Ref: TM-T3971
1mg35,00€2mg50,00€5mg71,00€1mL*10mM (DMSO)71,00€10mg114,00€25mg178,00€50mg268,00€100mg413,00€500mg888,00€NU 7026
CAS:NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibitionFórmula:C17H15NO3Pureza:99.51% - >99.99%Cor e Forma:SolidPeso molecular:281.314EGI-1
CAS:4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).Fórmula:C18H12Cl2N4O4SPureza:96.8% - 99.12%Cor e Forma:SolidPeso molecular:451.28Lithocholic acid
CAS:Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!Fórmula:C24H40O3Pureza:98% - 99.93%Cor e Forma:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Peso molecular:376.57SKF-96365 hydrochloride
CAS:SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFórmula:C22H27ClN2O3Pureza:99.47% - 99.92%Cor e Forma:SolidPeso molecular:402.91Ref: TM-T2170
5mg54,00€1mL*10mM (DMSO)59,00€10mg81,00€25mg131,00€50mg230,00€100mg445,00€200mg680,00€500mg1.054,00€Xanthohumol
CAS:Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-Fórmula:C21H22O5Pureza:98.19% - 99.67%Cor e Forma:Orange PowderPeso molecular:354.40NSC 66811
CAS:NSC 66811 inhibits MDM2-p53 interaction with 120 nM affinity, activating p53 in cancer cells.Fórmula:C23H20N2OPureza:96.94%Cor e Forma:SolidPeso molecular:340.42Palmatine
CAS:Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.Fórmula:C21H22NO4Pureza:96.28% - 99.49%Cor e Forma:SolidPeso molecular:352.4Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Fórmula:C35H30N4O4Pureza:97.61% - >99.99%Cor e Forma:SolidPeso molecular:570.64Ref: TM-T3211
1mg49,00€5mg84,00€1mL*10mM (DMSO)90,00€10mg119,00€25mg205,00€50mg310,00€100mg462,00€500mg1.035,00€Suramin Sodium Salt
CAS:Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.Fórmula:C51H34N6Na6O23S6Pureza:97.47% - 99.97%Cor e Forma:WhitePeso molecular:1429.15(S)-10-Hydroxycamptothecin
CAS:(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.Fórmula:C20H16N2O5Pureza:99.09% - 99.81%Cor e Forma:SolidPeso molecular:364.35AZD0156
CAS:AZD0156 , an effective and specific inhibitors of ATM kinase, is potential antineoplastic activities and chemo-/radio-sensitizing.Fórmula:C26H31N5O3Pureza:99.13% - 99.87%Cor e Forma:SolidPeso molecular:461.56TG101209
CAS:TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.Fórmula:C26H35N7O2SPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:509.67MGCD-265 analog
CAS:Glesatinib, an oral tyrosine kinase inhibitor, targets c-Met and VEGFR2 with IC50s of 29 nM and 10 nM, may treat cancer.Fórmula:C26H20FN5O2S2Pureza:98.06% - 98.68%Cor e Forma:SolidPeso molecular:517.6Ref: TM-T6351
100mgA consultar2mg34,00€5mg50,00€1mL*10mM (DMSO)58,00€10mg80,00€25mg156,00€50mg241,00€Ginsenoside Rg1
CAS:Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng).Fórmula:C42H72O14Pureza:99% - 99.92%Cor e Forma:White Crystalline PowderPeso molecular:801.01Valinomycin
CAS:Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes ParkinFórmula:C54H90N6O18Pureza:95.37% - 97.16%Cor e Forma:White SolidPeso molecular:1111.32Boc-Asp(OMe)-fluoromethyl ketone
CAS:Boc-Asp(OMe)-FMK is a broad-spectrum caspase inhibitor that blocks Fas-mediated processes without affecting IL-8 chemotaxis.Fórmula:C11H18FNO5Pureza:≥98%Cor e Forma:SolidPeso molecular:263.26LYN-1604
CAS:LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.Fórmula:C33H43Cl2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:584.62BMS-202
CAS:BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.Fórmula:C25H29N3O3Pureza:97.92% - 99.66%Cor e Forma:SolidPeso molecular:419.52SP2509
CAS:SP2509 is a specific histone demethylase LSD1 inhibitor(IC50 =13 nM).Fórmula:C19H20ClN3O5SPureza:98.82% - 99.53%Cor e Forma:SolidPeso molecular:437.9PU02
CAS:PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor.Fórmula:C16H12N4SPureza:99.35%Cor e Forma:SolidPeso molecular:292.36Kaempferol
CAS:Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.Fórmula:C15H10O6Pureza:98% - 99.41%Cor e Forma:Yellow Needles From Alcohol And Water SolidPeso molecular:286.24physalin F
CAS:Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.Cost-effective and quality-assured.Fórmula:C28H30O10Pureza:99.5% - 99.61%Cor e Forma:SolidPeso molecular:526.53Apitolisib
CAS:Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, γ (IC50= 5, 27, 7, 14 nM).Fórmula:C23H30N8O3SPureza:98.28% - 99.64%Cor e Forma:SolidPeso molecular:498.6Kobe0065
CAS:Kobe0065: novel small-molecule, inhibits Ras–Raf, Ki=46±13 μM, blocks H-Ras·GTP/c-Raf-1 RBD binding.Fórmula:C15H11ClF3N5O4SPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:449.79α-Mangostin
CAS:alpha-Mangostin (Mangostin) is a natural xanthonoid, a type of organic compound isolated from various parts of the mangosteen tree.Fórmula:C24H26O6Pureza:98.22% - 99.84%Cor e Forma:Yellow PowderPeso molecular:410.46DPN
CAS:DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .Fórmula:C15H13NO2Pureza:99.01%Cor e Forma:Off-White SolidPeso molecular:239.27Selumetinib
CAS:Selumetinib (AZD6244) is a selectivity and non-ATP-competitive MEK1/2 inhibitor. Selumetinib has antitumor activity. Cost-effective and quality-assured.Fórmula:C17H15BrClFN4O3Pureza:98.1% - 99.90%Cor e Forma:White Or Pale White SolidPeso molecular:457.68
