Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5600 produtos de "Apoptose"
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Rotenone
CAS:<p>Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.</p>Fórmula:C23H22O6Pureza:89.58% - 99.88%Cor e Forma:Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Peso molecular:394.42Epibrassinolide
CAS:<p>Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with</p>Fórmula:C28H48O6Pureza:97.57% - 98.11%Cor e Forma:SolidPeso molecular:480.68PIK-75
CAS:<p>PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).</p>Fórmula:C16H14BrN5O4SPureza:98.52% - >99.99%Cor e Forma:SolidPeso molecular:452.28Levomenol
CAS:<p>Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.</p>Fórmula:C15H26OPureza:96.01%Cor e Forma:Clear To Yellowish LiquidPeso molecular:222.37PKR-IN-C16
CAS:<p>PKR-IN-C16: inhibits PKR autophosphorylation and translation blockade; binds ATP site; IC50 of 186-210 nM; protects cells from ER stress damage.</p>Fórmula:C13H8N4OSPureza:97.8%Cor e Forma:SolidPeso molecular:268.29Neferine
CAS:<p>Neferine: anti-tumor, enhances DOX efficacy, prevents diabetic vasculopathy; mediates via CYP3A4, GSH depletion, blocks ROS/Akt/NF-κB.</p>Fórmula:C38H44N2O6Pureza:98.81% - 99.65%Cor e Forma:SolidPeso molecular:624.77Momordin Ic
CAS:<p>Momordin Ic (Momordin 1c) might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction</p>Fórmula:C41H64O13Pureza:98% - 99.69%Cor e Forma:SolidPeso molecular:764.94Isoalantolactone
CAS:<p>Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.</p>Fórmula:C15H20O2Pureza:99.75% - 99.94%Cor e Forma:SolidPeso molecular:232.32Zoledronic acid monohydrate
CAS:<p>Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.</p>Fórmula:C5H12N2O8P2Pureza:99.91%Cor e Forma:White To Off-White PowderPeso molecular:290.1Toddaculin
CAS:<p>Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the</p>Fórmula:C16H18O4Pureza:99.91%Cor e Forma:SolidPeso molecular:274.31Infigratinib
CAS:<p>Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and</p>Fórmula:C26H31Cl2N7O3Pureza:98% - 98.97%Cor e Forma:SolidPeso molecular:560.48Bacopaside II
CAS:<p>Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis.</p>Fórmula:C47H76O18Pureza:98.14% - 99.86%Cor e Forma:SolidPeso molecular:929.1Evocarpine
CAS:<p>Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.</p>Fórmula:C23H33NOPureza:99.77% - 99.819%Cor e Forma:SolidPeso molecular:339.51IC261
CAS:<p>IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.</p>Fórmula:C18H17NO4Pureza:99.45% - 99.91%Cor e Forma:SolidPeso molecular:311.33Vesatolimod
CAS:<p>Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.</p>Fórmula:C22H30N6O2Pureza:97.46% - 99.03%Cor e Forma:SolidPeso molecular:410.51Dienogest
CAS:<p>Dienogest (STS 557), an oral 4th-gen progestogen, is used in hormone therapy and contraception with antiandrogenic effects.</p>Fórmula:C20H25NO2Pureza:98% - 99.43%Cor e Forma:Pale Yellow SolidPeso molecular:311.42(S)-crizotinib
CAS:<p>(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.</p>Fórmula:C21H22Cl2FN5OPureza:98.52% - 99.47%Cor e Forma:SolidPeso molecular:450.34Salubrinal
CAS:<p>Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).</p>Fórmula:C21H17Cl3N4OSPureza:97.25% - >99.99%Cor e Forma:SolidPeso molecular:479.81Choline
CAS:<p>Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins</p>Fórmula:C5H15NO2Pureza:99.97% - ≥98%Cor e Forma:LiquidPeso molecular:121.18MPTP hydrochloride
CAS:<p>MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.</p>Fórmula:C12H16ClNPureza:96.35% - >99.99%Cor e Forma:SolidPeso molecular:209.72CHR-6494 TFA
CAS:<p>CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.</p>Fórmula:C18H17F3N6O2Pureza:99.50%Cor e Forma:SolidPeso molecular:406.36Obatoclax Mesylate
CAS:Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, andFórmula:C20H19N3O·CH4O3SPureza:99.58% - 99.88%Cor e Forma:SolidPeso molecular:413.49CCT007093
CAS:<p>CCT007093 is an effective PPM1D (WIP1) inhibitor (IC50: 8.4 μM).</p>Fórmula:C15H12OS2Pureza:98% - 99.88%Cor e Forma:SolidPeso molecular:272.39Isocurcumenol
CAS:<p>1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).</p>Fórmula:C15H22O2Pureza:99.29% - ≥95%Cor e Forma:SolidPeso molecular:234.33Neobavaisoflavone
CAS:<p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>Fórmula:C20H18O4Pureza:99.31% - 99.87%Cor e Forma:SolidPeso molecular:322.35RGX-202
CAS:<p>RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.</p>Fórmula:C4H9N3O2Pureza:99.67% - 99.8%Cor e Forma:SolidPeso molecular:131.13PD173955
CAS:<p>PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and</p>Fórmula:C21H16Cl2N4OSPureza:98.52% - 98.99%Cor e Forma:SolidPeso molecular:443.35Nobiletin
CAS:<p>Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.</p>Fórmula:C21H22O8Pureza:98.65% - 99.76%Cor e Forma:SolidPeso molecular:402.39Bioymifi
CAS:<p>Bioymifi (DR5 Activator), a novel TRAIL activator, binds to DR5's ECD, inducing DR5 aggregation and stimulating cell apoptosis. Cost-effective and quality-assured.</p>Fórmula:C22H12BrN3O4SPureza:98% - 99.79%Cor e Forma:SolidPeso molecular:494.32Oncrasin-1
CAS:<p>Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations</p>Fórmula:C16H12ClNOPureza:99.75%Cor e Forma:SolidPeso molecular:269.73TD52
CAS:<p>TD52, an Erlotinib derivative, is an oral CIP2A cancer inhibitor that disrupts Elk1's attachment to the CIP2A promoter.</p>Fórmula:C24H16N4Pureza:99.5%Cor e Forma:SolidPeso molecular:360.41DB1976 dihydrochloride
CAS:<p>DB1976 dihydrochloride (DB1976 2HCl), a transcription factor PU.1 inhibitor, has potential anti-inflammatory activity for the study of metabolic dysfunction.</p>Fórmula:C20H18Cl2N8SePureza:99.08%Cor e Forma:SolidPeso molecular:520.28EPZ004777 hydrochloride
CAS:<p>EPZ004777 hydrochloride (EPZ004777 HCl) is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.</p>Fórmula:C28H42ClN7O4Cor e Forma:SolidPeso molecular:576.13Enzastaurin
CAS:<p>Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.</p>Fórmula:C32H29N5O2Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:515.6Tasisulam
CAS:<p>Tasisulam (LY573636) is an apoptosis inducer and an antitumor agent via the intrinsic pathway.</p>Fórmula:C11H6BrCl2NO3S2Pureza:99% - >99.99%Cor e Forma:SolidPeso molecular:415.11VLX600
CAS:<p>VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent.</p>Fórmula:C17H15N7Pureza:98.62%Cor e Forma:SolidPeso molecular:317.35Chlorfenapyr
CAS:<p>Chlorfenapyr (AC 303630) is a pyrrole insecticide and converts active substances (insecticidal activity) in insects by a multifunctional oxidase</p>Fórmula:C15H11BrClF3N2OPureza:99.33% - 99.49%Cor e Forma:Off-White To Light Brown Powder With An Halide OdorPeso molecular:407.61Autophagy-IN-A9
CAS:<p>Autophagy-IN-A9 is a bioactive chemical.</p>Fórmula:C15H11ClFN3Pureza:99.72%Cor e Forma:SolidPeso molecular:287.72Thalidomide 5-fluoride
CAS:<p>Thalidomide 5-fluoride (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-) is a thalidomide-based Cereblon ligand that binds to the IRAK4 protein</p>Fórmula:C13H9FN2O4Pureza:98.62%Cor e Forma:SolidPeso molecular:276.22Etonogestrel
CAS:<p>Etonogestrel (Implanon) is a steroidal progestin used as hormonal contraceptives.</p>Fórmula:C22H28O2Pureza:99.59% - 99.59%Cor e Forma:SolidPeso molecular:324.46Larotrectinib
CAS:<p>Larotrectinib (LOXO-101) is an orally administered inhibitor of the TRK kinase and is highly selective only for the TRK family of receptors(IC50s = 2-20 nM).</p>Fórmula:C21H22F2N6O2Pureza:99.15% - >99.99%Cor e Forma:SolidPeso molecular:428.44Piclidenoson
CAS:<p>Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.</p>Fórmula:C18H19IN6O4Pureza:99.83% - ≥95%Cor e Forma:SolidPeso molecular:510.29Pyraclostrobin
CAS:<p>Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.</p>Fórmula:C19H18ClN3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:387.82SKLB4771
CAS:<p>SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.</p>Fórmula:C25H27N7O3S2Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:537.664-Hydroxybenzyl alcohol
CAS:<p>4-Hydroxybenzyl alcohol aids brain injury recovery, boosts Nrf2/Prdx6/PDI, and hinders angiogenesis, showing promise in cancer therapy.</p>Fórmula:C7H8O2Pureza:97.65% - 98.25%Cor e Forma:SolidPeso molecular:124.14Minodronic acid monohydrate
CAS:<p>Minodronic acid monohydrate 是一种法尼基二磷酸合成酶抑制剂，可作为骨吸收抑制剂。</p>Fórmula:C9H14N2O8P2Pureza:≥95%Cor e Forma:SolidPeso molecular:340.16Quiflapon sodium
CAS:<p>Quiflapon sodium (MK591) is a selective inhibitor of 5-Lipoxygenase-activating protein (FLAP).</p>Fórmula:C34H35ClN2NaO3SPureza:98%Cor e Forma:SolidPeso molecular:610.16S-99
CAS:<p>S-99 is a high purity chemical that targets ASK and is important for Immunology, Inflammation, Cancer research.</p>Fórmula:C16H15F3N6OPureza:99.61%Cor e Forma:SolidPeso molecular:364.33HLCL-61 hydrochloride
CAS:<p>HLCL-61 hydrochloride (HLCL-61 HCL) is a potent and selective PRMT5 inhibitor for the treatment of acute myeloid leukemia.</p>Fórmula:C23H24N2O·ClHPureza:99.88% - 99.95%Cor e Forma:SolidPeso molecular:380.91ABT-751
CAS:<p>ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.</p>Fórmula:C18H17N3O4SPureza:98.84% - 99.50%Cor e Forma:SolidPeso molecular:371.41
