Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(134 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6223 produtos de "Apoptose"
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L-Asparaginase
CAS:L-Asparaginase, an enzyme for acute lymphoblastic leukemia treatment, is administered via injection.Fórmula:NAPureza:97%Cor e Forma:SolidPeso molecular:N/ASGI-1776
CAS:SGI-1776 (Pim-Kinase Inhibitor IX) has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.Fórmula:C20H22F3N5OPureza:99.3% - >99.99%Cor e Forma:SolidPeso molecular:405.42Ref: TM-T3078
1mgA consultar5mg90,00€1mL*10mM (DMSO)94,00€10mg145,00€25mg281,00€50mg409,00€100mg528,00€Elesclomol
CAS:Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier.Fórmula:C19H20N4O2S2Pureza:97.17% - 99.51%Cor e Forma:SolidPeso molecular:400.52Rilmenidine Phosphate
CAS:Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.Fórmula:C10H19N2O5PPureza:99.99% - ≥95%Cor e Forma:SolidPeso molecular:278.24Ref: TM-T6641
1mg34,00€5mg67,00€1mL*10mM (DMSO)67,00€10mg93,00€25mg152,00€50mg230,00€100mg363,00€200mg528,00€HO-3867
CAS:HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor.Fórmula:C28H30F2N2O2Pureza:91.18% - 99.21%Cor e Forma:SolidPeso molecular:464.55LRRK2-IN-1
CAS:LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.Fórmula:C31H38N8O3Pureza:98% - 98.82%Cor e Forma:SolidPeso molecular:570.69kauran-16,17-diol
CAS:Kauran-16,17-diol, a natural diterpenoid product, exhibits anti-tumoral and apoptosis-inducing activities by inhibiting NO production in LPS-induced RAW 264.7Fórmula:C20H34O2Pureza:99.93%Cor e Forma:SolidPeso molecular:306.48Ref: TM-T4951
1mg64,00€1mL*10mM (DMSO)163,00€5mg170,00€10mg245,00€25mg371,00€50mg504,00€100mg675,00€200mg900,00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Fórmula:C9H6O4Pureza:97.47% - 99.8%Cor e Forma:SolidPeso molecular:178.14S-trityl-L-Cysteine
CAS:S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5Fórmula:C22H21NO2SPureza:97.02%Cor e Forma:Almost White To Light Yellow Granular PowderPeso molecular:363.47NSC 95397
CAS:NSC 95397 is a potent inhibitor of Cdc25 dual specificity phosphatase(Ki of 32, 96, and 40 nM for Cdc25A, Cdc25B, and Cdc25C, respectively).Fórmula:C14H14O4S2Pureza:98.66%Cor e Forma:SolidPeso molecular:310.39Diffractaic Acid
CAS:Diffractaic Acid (NSC 685595) can inhibit LTB4 biosynthesis in A-23187-stimulated bovine PMNL cells with activity value of 8 μM.Fórmula:C20H22O7Pureza:99.81% - 99.87%Cor e Forma:SolidPeso molecular:374.38SKI II
CAS:SKI II is a selective non-ATP S1P receptor inhibitor with an IC50 of 0.5 μM; it doesn't inhibit PKCα, PI3K, or ERK2.Fórmula:C15H11ClN2OSPureza:99.34% - 99.93%Cor e Forma:SolidPeso molecular:302.78[6]-Gingerol
CAS:[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.Fórmula:C17H26O4Pureza:98% - 99.95%Cor e Forma:Light Yellow OilinessPeso molecular:294.39STF-118804
CAS:STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Fórmula:C25H23N3O4SPureza:98.66%Cor e Forma:SolidPeso molecular:461.53GSK1059615
CAS:GSK1059615 has been used in trials studying the treatment of Lymphoma, Solid Tumours, Endometrial Cancer, Solid Tumor Cancer, and Metastatic Breast Cancer.Fórmula:C18H11N3O2SPureza:99.3% - ≥95%Cor e Forma:SolidPeso molecular:333.36GMB-475
CAS:GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.Fórmula:C43H46F3N7O7SPureza:98.78% - >99.99%Cor e Forma:SolidPeso molecular:861.93Ref: TM-T8488
1mg50,00€2mg66,00€5mg99,00€1mL*10mM (DMSO)152,00€10mg160,00€25mg281,00€50mg416,00€100mg600,00€200mg835,00€2-Hydroxychalcone
CAS:2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.Fórmula:C15H12O2Pureza:99.6%Cor e Forma:SolidPeso molecular:224.25Pracinostat
CAS:Pracinostat (SB939) is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in Clinicalal trials, allowing oralFórmula:C20H30N4O2Pureza:99.15% - 99.67%Cor e Forma:SolidPeso molecular:358.48Ref: TM-T1890
1mg48,00€2mg64,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg152,00€25mg268,00€50mg401,00€100mg592,00€200mg835,00€Phellamurin
CAS:Phellamurin blocks intestinal P-glycoprotein dose-dependently and it seriously interacts with cyclosporin; coadministration should be avoided.Fórmula:C26H30O11Pureza:97.91%Cor e Forma:SolidPeso molecular:518.51Ref: TM-TN4761
1mg155,00€5mg304,00€1mL*10mM (DMSO)389,00€10mg447,00€25mg713,00€50mg1.018,00€100mg1.369,00€Astragalin
CAS:Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid.Fórmula:C21H20O11Pureza:98.8% - ≥95%Cor e Forma:SolidPeso molecular:448.38Ref: TM-T6S1101
1mg34,00€5mg62,00€1mL*10mM (DMSO)73,00€10mg86,00€25mg126,00€50mg178,00€100mg263,00€500mg645,00€Dinaciclib
CAS:Dinaciclib (SCH 727965) is a CDK inhibitor that selectively inhibits CDK1, CDK2, CDK5, and CDK9 (IC50 = 3/1/1/4 nM).Fórmula:C21H28N6O2Pureza:98.21% - 99.75%Cor e Forma:SolidPeso molecular:396.49Etidronic acid
CAS:Etidronic acid (HEDP) is a diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.Fórmula:C2H8O7P2Pureza:99.93% - ≥95%Cor e Forma:Liquid SyrupPeso molecular:206.03Nafamostat mesylate
CAS:Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitisFórmula:C19H17N5O2·2CH4O3SPureza:97.36% - 99.76%Cor e Forma:Tan To Pale Orange SolidPeso molecular:539.58KW-2449
CAS:KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.Fórmula:C20H20N4OPureza:98.43% - 99.69%Cor e Forma:SolidPeso molecular:332.4WYC-209
CAS:WYC-209 inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs, IC50: 0.19 uM). It targets the retinoic acid receptor (RAR).Fórmula:C20H20N2O3SPureza:99.77%Cor e Forma:SolidPeso molecular:368.45Amentoflavone
CAS:Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications.Fórmula:C30H18O10Pureza:98.21% - 99.22%Cor e Forma:Odourless Whitish SolidPeso molecular:538.46Ref: TM-T3417
2mg34,00€5mg50,00€1mL*10mM (DMSO)59,00€10mg80,00€25mg126,00€50mg215,00€100mg349,00€200mg512,00€BAY 61-3606
CAS:BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting
Fórmula:C20H18N6O3Pureza:98.72%Cor e Forma:SolidPeso molecular:390.4Niraparib tosylate monohyrate
CAS:Niraparib (MK-4827), a PARP inhibitor, boosts DNA breaks to trigger genomic instability and apoptosis, offering anti-cancer effects.Fórmula:C26H30N4O5SPureza:97.7% - 99.99%Cor e Forma:SolidPeso molecular:510.61Ref: TM-T9497
5mg57,00€1mL*10mM (DMSO)66,00€10mg82,00€25mg111,00€50mg137,00€100mg205,00€200mg309,00€500mg515,00€Sacubitril/Valsartan
CAS:Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for treatment of hypertension and heart failure.Fórmula:C48H55N6O8Na3·5H2OPureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:957.99Ref: TM-T2318
2mg43,00€5mg63,00€10mg88,00€1mL*10mM (DMSO)93,00€25mg117,00€50mg147,00€100mg178,00€500mg442,00€SKI-178
CAS:SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM.Fórmula:C21H22N4O4Pureza:97.09%Cor e Forma:SolidPeso molecular:394.42Ref: TM-T9014
2mg46,00€5mg69,00€1mL*10mM (DMSO)75,00€10mg108,00€25mg203,00€50mg326,00€100mg492,00€500mg1.054,00€Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Cor e Forma:SolidPeso molecular:718.08Etretinate
CAS:Etretinate (Ro 10-9359), an oral retinoid, treats psoriasis by promoting cell differentiation and reducing cell growth and inflammation.Fórmula:C23H30O3Pureza:97.89%Cor e Forma:Crystals Crystalline SolidPeso molecular:354.48Sepantronium bromide
CAS:Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.
Fórmula:C20H19BrN4O3Pureza:99.68% - 99.85%Cor e Forma:SolidPeso molecular:443.26Psoralen
CAS:Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
Fórmula:C11H6O3Pureza:99.3% - 99.87%Cor e Forma:Crystals From Ether Crystalline SolidPeso molecular:186.16Clodronate disodium tetrahydrate
CAS:Clodronate disodium tetrahydrate (Clastoban) inhibits bone resorption and soft tissue calcification.Fórmula:CH10Cl2Na2O10P2Pureza:98%Cor e Forma:SolidPeso molecular:360.92CM-272
CAS:CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.Fórmula:C28H38N4O3Pureza:97.83%Cor e Forma:SolidPeso molecular:478.63Isolongifolene
CAS:Isolongifolene ((-)-Isolongifolene), a tricyclic sesquiterpene isolated from Murraya koenigii, exhibits antioxidant, anti-inflammatory, anticancer, andFórmula:C15H24Pureza:90.13% - 99.46%Cor e Forma:Colorless Or Light Yellow LiquidPeso molecular:204.35ERK1/2 inhibitor 2
CAS:ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable ERK 1/2 inhibitor, with potential antineoplastic activity.Fórmula:C29H31ClFN5O5Pureza:98.99%Cor e Forma:SolidPeso molecular:584.04Trifloxystrobin
CAS:Trifloxystrobin is a fungicide against R. solani in sugar beets with EC50s: 23.0 μg/L for Daphnia neonates, 1.7 μg/L for embryos.Fórmula:C20H19F3N2O4Pureza:99.49%Cor e Forma:SolidPeso molecular:408.37LY294002
CAS:LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Fórmula:C19H17NO3Pureza:98% - 99.96%Cor e Forma:Pale Yellow SolidPeso molecular:307.34JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Fórmula:C20H20Cl2N4O4Pureza:98.02% - 98.4%Cor e Forma:SolidPeso molecular:451.3Ref: TM-T37314
1mg49,00€5mg105,00€1mL*10mM (DMSO)117,00€10mg170,00€25mg281,00€50mg439,00€100mg708,00€200mg964,00€QNZ
CAS:QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.Fórmula:C22H20N4OPureza:99.17% - 99.18%Cor e Forma:White SolidPeso molecular:356.42Ref: TM-T6204
1mg40,00€2mg54,00€1mL*10mM (DMSO)87,00€5mg88,00€10mg133,00€25mg178,00€50mg313,00€100mg465,00€200mg673,00€Bardoxolone
CAS:Bardoxolone (CDDO) inhibits iNOS, COX-2 in cells; IC50=0.4nM. Reduces ROS/RNS, DNA damage, & cancer growth; triggers apoptosis & boosts antioxidant genes.Fórmula:C31H41NO4Pureza:97.9% - 98.97%Cor e Forma:SolidPeso molecular:491.66Thalidomide-O-C4-NH2 hydrochloride
CAS:Thalidomide-linker 9: a cereblon ligand, E3 ligase conjugate for PROTAC tech.Fórmula:C17H20ClN3O5Pureza:98.33%Cor e Forma:SolidPeso molecular:381.81Dihydrocapsaicin
CAS:Dihydrocapsaicin, similar to capsaicin, is an irritant found in Capsicum, used in "pure" capsaicin products at about 10%, activates VR1, and is an antioxidant.Fórmula:C18H29NO3Pureza:99.8% - ≥95%Cor e Forma:White CrystalPeso molecular:307.43Laquinimod sodium
CAS:Laquinimod (ABR-215062) sodium is an oral agent for MS, halting neurodegeneration and inflammation.Fórmula:C19H16ClN2NaO3Cor e Forma:SolidPeso molecular:378.79Thalidomide-PEG4-Propargyl
CAS:Thalidomide-PEG4-Propargyl is a synthetic E3 ligase ligand for PROTAC with a cereblon ligand and linker.Fórmula:C24H28N2O9Pureza:97.46%Cor e Forma:SolidPeso molecular:488.49PFI-1
CAS:PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.Fórmula:C16H17N3O4SPureza:98.74% - 99.19%Cor e Forma:SolidPeso molecular:347.39MCB-613
CAS:MCB-613 is an effective steroid receptor coactivator (SRC) stimulator.Fórmula:C20H20N2OPureza:98.17% - 99.754%Cor e Forma:SolidPeso molecular:304.39Ref: TM-T6886
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg137,00€25mg245,00€50mg358,00€100mg537,00€SKLB-163
CAS:SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.Fórmula:C18H16ClN3O2S2Pureza:99.23%Cor e Forma:SolidPeso molecular:405.92Ref: TM-T26193
1mg128,00€5mg303,00€1mL*10mM (DMSO)335,00€10mg447,00€25mg713,00€50mg1.018,00€100mg1.369,00€500mg2.673,00€
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