Proteases/Proteassoma

Os inibidores de proteases e proteassomas são compostos que bloqueiam a atividade das proteases e do proteassoma, que estão envolvidos na degradação e renovação de proteínas. Esses inibidores são vitais para estudar a regulação da homeostase de proteínas, controle do ciclo celular e apoptose. Inibidores de proteases e proteassomas também são utilizados no tratamento de doenças como o câncer, onde a degradação anormal de proteínas desempenha um papel na progressão da doença. Ao inibir proteases ou o proteassoma, esses compostos podem induzir a morte celular em células cancerígenas e são ferramentas essenciais tanto na pesquisa básica quanto no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma ampla gama de inibidores de proteases e proteassomas de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento de medicamentos.

Subcategorias de "Proteases/Proteassoma"

Exibir 3 mais subcategorias

Foram encontrados 1092 produtos de "Proteases/Proteassoma"

Pureza (%)

100

produtos por página.

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NIM811
CAS:
- 143205-42-9
NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.
Fórmula:C₆₂H₁₁₁N₁₁O₁₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:1202.635
Ref: TM-T12226
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Rivulariapeptolides 1155
Rivulariapeptolides 1155 inhibits chymotrypsin (41.84 nM), elastase (4.94 nM), and proteinase K (56.54 nM).
Fórmula:C₅₉H₈₁N₉O₁₅
Cor e Forma:Solid
Peso molecular:1156.33
Ref: TM-T75648
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HB-2-30
CAS:
- 3031522-14-9
HB-2-30 is a far-red fluorescent transglutaminase 2 (TG2) probe for in vitro and in vivo endocytosis imaging. HB-2-30 complexes with TG2 and α2-macroglobulin for efficient endocytosis via the LRP1 pathway.
Fórmula:C₆₆H₈₆N₁₀O₁₄S₂
Peso molecular:1307.58
Ref: TM-T204998
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CL 82198 hydrochloride
CAS:
- 1188890-36-9
CL 82198 hydrochloride selectively inhibits MMP-13, not MMP-1/9/TACE, and blocks HP75 invasion and neurotoxicity in zebrafish.
Fórmula:C₁₇H₂₃ClN₂O₃
Cor e Forma:Solid
Peso molecular:338.83
Ref: TM-T41179
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PSI-353661
CAS:
- 1231747-08-2
PSI-353661 (GS-558093), inhibits HCV's NS5B polymerase; EC90: 8nM (wild-type), 11nM (S282T); active in human hepatocytes.
Fórmula:C₂₄H₃₂FN₆O₈P
Cor e Forma:Solid
Peso molecular:582.52
Ref: TM-T74301
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GSK2818713
CAS:
- 1422484-32-9
GSK2818713 is a novel Hepatitis C NS5A replication complex inhibitor.
Fórmula:C₄₆H₅₆N₈O₈
Cor e Forma:Solid
Peso molecular:849.002
Ref: TM-T38858
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VD2173
CAS:
- 2574389-19-6
VD2173: a macrocyclic peptide that inhibits HGF serine proteases, matriptase, and hepsin, potentially for lung cancer research.
Fórmula:C₃₁H₄₅N₉O₆S
Cor e Forma:Solid
Peso molecular:671.81
Ref: TM-T74390
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HIV-1 Rev (34-50)
CAS:
- 141237-50-5
HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity.
Fórmula:C₉₇H₁₇₃N₅₁O₂₄
Pureza:99.91%
Cor e Forma:Solid
Peso molecular:2437.74
Ref: TM-TP1149
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HCV-IN-7 hydrochloride
CAS:
- 1449756-87-9
HCV-IN-7 hydrochloride: Oral, potent HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.
Fórmula:C₄₀H₅₀Cl₂N₈O₆S
Pureza:98%
Cor e Forma:Solid
Peso molecular:841.85
Ref: TM-T11548L
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PPACK II
CAS:
- 74392-49-7
PPACK II is an irreversible and specific glandular and plasma kallikreins inhibitor [1] .
Fórmula:C₂₅H₃₃ClN₆O₃
Cor e Forma:Solid
Peso molecular:501.02
Ref: TM-T73863
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Recombinant Proteinase K
Recombinant Proteinase K: serine protease, cleaves carboxy-terminus peptides, digests proteins, purifies nucleic acids.
Cor e Forma:Solid
Ref: TM-T76202
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Ichorcumab
CAS:
- 2589583-20-8
Ichorcumab (JNJ-375) is a fully human IgG4 antibody that targets thrombin. It binds to exosite 1 of thrombin, inhibiting substrate binding without affecting its catalytic activity. For isotype control, refer to HumanIgG1kappa, Isotype Control.
Cor e Forma:Liquid
Ref: TM-T9901A-779
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Relacatib
CAS:
- 362505-84-8
Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.
Fórmula:C₂₇H₃₂N₄O₆S
Cor e Forma:Solid
Peso molecular:540.64
Ref: TM-T40463
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Tyrosinase/elastase-IN-1
Tyrosinase/elastase-IN-1, a triterpenoid extracted from the leaves of Rubus fraxinifolius, exhibits inhibitory activities against both tyrosinase and elastase
Fórmula:C₃₃H₅₂O₅
Cor e Forma:Solid
Peso molecular:528.76
Ref: TM-T74243
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5-epi-Arvestonate A
CAS:
- 2767066-84-0
5-epi-Arvestonate A, a sesquiterpenoid from Seriphidium transiliense, stimulates melanogenesis and suppresses IFN-γ-chemokine in HaCaT cells.
Fórmula:C₁₆H₂₆O₅
Cor e Forma:Solid
Peso molecular:298.37
Ref: TM-T75535
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PS 915
CAS:
- 86356-77-6
PS 915 is a substrate for colorimetric assay. It was used for plasma antithrombin.
Fórmula:C₂₇H₃₆ClN₇O₆
Pureza:98%
Cor e Forma:Solid
Peso molecular:590.08
Ref: TM-T24674
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Rivulariapeptolides 1121
Rivulariapeptolides 1121 inhibits serine proteases: chymotrypsin (IC50=35.52 nM), elastase (13.24 nM), proteinase K (48.05 nM).
Fórmula:C₅₆H₈₃N₉O₁₅
Cor e Forma:Solid
Peso molecular:1122.31
Ref: TM-T75650
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KKI-5
CAS:
- 97145-43-2
KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.
Fórmula:C₃₅H₅₅N₁₁O₉
Pureza:98%
Cor e Forma:Solid
Peso molecular:773.88
Ref: TM-TP1792
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Histargin
CAS:
- 93361-66-1
Histargin is an enzyme inhibitor separated from Streptomyces roseoviridis.
Fórmula:C₁₄H₂₅N₇O₄
Cor e Forma:Solid
Peso molecular:355.39
Ref: TM-T25504
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LXE408 fumarate
LXE408 fumarate: orally available, selective kinetoplastid proteasome inhibitor with IC50/EC50 of 0.04 μM for L. donovani; potentially aids in VL research.
Fórmula:C₂₇H₂₂FN₇O₆
Pureza:99.89%
Cor e Forma:Soild
Peso molecular:559.51
Ref: TM-T39214L