GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.948 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(409 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5373 produtos de "GPCR/Proteína-G"
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Pasireotide L-aspartate salt
CAS:<p>Pasireotide L-aspartate, a stable cyclohexapeptide, mimics somatostatin with high affinity for sst1/2/3/4/5 receptors (pKi=8.2/9.0/9.1/<7.0/9.9).</p>Fórmula:C62H73N11O13Pureza:98%Cor e Forma:SolidPeso molecular:1180.33Neuromedin N
CAS:<p>Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.</p>Fórmula:C38H63N7O8Pureza:98%Cor e Forma:SolidPeso molecular:745.95Urocortin, rat
CAS:<p>Endogenous CRF agonist. Ki values are 13, 1.5 and 0.97 nM for hCRF1, rCRF2α and mCRF2β respectively.</p>Fórmula:C206H338N62O64Pureza:98%Cor e Forma:SolidPeso molecular:4707.26Isoprenaline
CAS:<p>Isoprenaline is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.</p>Fórmula:C11H17NO3Pureza:99.31%Cor e Forma:SolidPeso molecular:211.26[Gln8]-C517 (LH-RH), chicken
CAS:[Gln8] LH-RH: Avian hypothalamic peptide; prompts anterior pituitary to release gonadotropins, controlling reproduction.Fórmula:C54H71N15O14Pureza:98%Cor e Forma:SolidPeso molecular:1154.23Antisauvagine-30 TFA
<p>aSvg-30 TFA: potent CRF2 receptor antagonist, Kd 1.4 nM (mCRFR2β), 150 nM (CRFR1).</p>Fórmula:C163H275N48F3O49SCor e Forma:SolidPeso molecular:3764.28Cholic Acid 7-sulfate
CAS:<p>Cholic acid 7-sulfate: a cholic acid metabolite with added sulfate at position 7, increased in feces of male mice with specific diets.</p>Fórmula:C24H40O8SCor e Forma:SolidPeso molecular:488.64α-CGRP, rat
CAS:Endogenous neuropeptide, potent vasodilatorFórmula:C162H262N50O52S2Pureza:98%Cor e Forma:SolidPeso molecular:3806.25Pancreatic Polypeptide, bovine
CAS:Agonist at Y4 neuropeptide Y receptors.Fórmula:C186H287N53O56S2Pureza:98%Cor e Forma:SolidPeso molecular:4225.78GLP-1R agonist 15
CAS:<p>GLP-1R agonist 15 (Compound 101) is a GLP-1 receptor agonist [1] .</p>Fórmula:C46H47FN8O7SCor e Forma:SolidPeso molecular:874.9815(S)-15-methyl Prostaglandin F2α methyl ester
CAS:<p>15(S)-15-methyl Prostaglandin F2α methyl ester can be used in related research in the field of life sciences.</p>Fórmula:C22H38O5Cor e Forma:SolidPeso molecular:382.53GLP-2(1-33)(human)
CAS:GLP-2(1-33) (human) is an enteroendocrine hormone which stimulates the growth of the intestinal epithelium.Fórmula:C165H254N44O55SPureza:98%Cor e Forma:SolidPeso molecular:3766.19Parstatin(mouse)
CAS:Peptide inhibits endothelial migration/proliferation (IC50 ~20μM), induces cell cycle arrest, triggers apoptosis, and has cardioprotective effects.Fórmula:C189H326N58O57S3Pureza:98%Cor e Forma:SolidPeso molecular:4419.19Adrogolide HCl
CAS:Adrogolide Hydrochloride is a selective dopamine receptor D1 agonist.Fórmula:C22H26ClNO4SCor e Forma:SolidPeso molecular:435.96Calcitonin (human)
CAS:<p>Endogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.</p>Fórmula:C151H226N40O45S3Pureza:98%Cor e Forma:White Lyophilized PowderPeso molecular:3417.87IRL-1620 acetate
<p>IRL-1620 acetate is an effective and selective agonist of Endothelin B receptor (ETB) with a Ki of 16 pM which is more selective than ETA with a Ki of 19 μM.</p>Fórmula:C88H121N17O29Pureza:96.64%Cor e Forma:SolidPeso molecular:1881LY-426965 hydrochloride
CAS:LY-426965 hydrochloride is a bioactive chemical.Fórmula:C28H39ClN2O2Cor e Forma:SolidPeso molecular:471.07(±)14(15)-EpETE
CAS:<p>(±)14(15)-EpETE is an intestinal microbial lipid metabolite that attenuates cisplatin chemotherapy-induced nausea in rats by inhibiting Substance P release.</p>Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.45FR167344 free base
CAS:<p>FR167344 free base: oral, nonpeptide B2 bradykinin receptor antagonist, high-affinity (IC50: 65 nM), no B1 affinity.</p>Fórmula:C30H28BrCl2N5O4Pureza:98%Cor e Forma:SolidPeso molecular:673.38rGHRH(1-29)NH2
RGHRH (1-29)NH2 is a synthetic peptide that stimulates the secretion of growth hormone (GH).Fórmula:C155H251N49O40SPureza:98%Cor e Forma:SolidPeso molecular:3473.02PAMP-12(human, porcine)
CAS:Potent endogenous peptide agonist of Mas related GPR X2 (MRGPRX2, EC50 = 57.2 nM). Corresponds to amino acids 9 to 20 of proadrenomedullin.Fórmula:C77H119N25O14Pureza:98%Cor e Forma:SolidPeso molecular:1618.95MMC(TMZ)-TOC TFA
<p>MMC(TMZ)-TOC TFA exhibits high binding affinity and selectivity for the somatostatin receptor subtype 2 (SSTR2). It targets the delivery of TMZ to SSTR2-positive tumor cells, making MMC(TMZ)-TOC TFA useful for cancer research.</p>Fórmula:C74H99F3N20O21S2Cor e Forma:SolidPeso molecular:1725.82Minaprine
CAS:<p>Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.</p>Fórmula:C17H22N4OPureza:98%Cor e Forma:SolidPeso molecular:298.38HAEGTFT
CAS:<p>HAEGTFT is the first N-terminal 1-7 residues of GLP-1 peptide.</p>Fórmula:C33H47N9O12Pureza:98%Cor e Forma:SolidPeso molecular:761.78WAY-639418
CAS:<p>WAY-639418 has potential anti-inflammatory and anti-HIV activity and can be used to study CCR5-mediated inflammatory and immunomodulatory diseases.</p>Fórmula:C17H16ClN5Pureza:99.62%Cor e Forma:SolidPeso molecular:325.8Exendin-3/4 (59-86)
<p>Exendin-3/4 (59-86) is a Exendin-4 peptide derivative.</p>Fórmula:NAPureza:98%Cor e Forma:SolidPeso molecular:3055.49CCR8 antagonist 1
CAS:<p>CCR8 antagonist 1 is an antagonist of C-C Motif Chemokine Receptor 8 (CCR8) with a Ki value of 1.6 nM.</p>Fórmula:C26H29N3O5SPureza:99.51%Cor e Forma:SolidPeso molecular:495.59PSMA/GRPR ligand 1
<p>PSMA/GRPR ligand 1 (compound 3) is a bispecific ligand with dual targeting capabilities for tumors that express PSMA(+) and GRPR(+).</p>Cor e Forma:Odour Solidγ-2-MSH (41-58), amide
CAS:Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor.Fórmula:C74H100N22O15SPureza:98%Cor e Forma:SolidPeso molecular:1569.79Linzagolix choline
CAS:<p>Linzagolix choline is a GnRH antagonist. It can be used to study pain associated with uterine fibroids and endometriosis.</p>Fórmula:C27H28F3N3O8SPureza:99.64%Cor e Forma:SolidPeso molecular:611.595-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Fórmula:C25H30N4O2SCor e Forma:SolidPeso molecular:450.6Benzomalvin B
CAS:<p>Benzomalvin B, a metabolite from Penicillium, blocks 24% NK1 receptor binding at 100 μg/ml.</p>Fórmula:C24H17N3O2Cor e Forma:SolidPeso molecular:379.419PG 931 acetate
<p>PG 931 acetate is a potent agonist of melanocortin 4 (MC4) receptors.</p>Fórmula:C61H89N15O13Pureza:98.74%Cor e Forma:SolidPeso molecular:1240.45CCR2 antagonist 1
CAS:CCR2 antagonist 1 is a high-affinity and long-residence-time antagonist of CCR2 (Ki: 2.4 nM).Fórmula:C28H32BrF3N2OCor e Forma:SolidPeso molecular:549.47Efranarelaxin alfa
CAS:<p>Efranarelaxin alfa is an agonist of the relaxin receptor. It shows potential for research in cardiovascular diseases and tissue repair.</p>Cor e Forma:LiquidAmylin (8-37), rat
CAS:<p>Amylin (8-37), rat, an analog of IAPP, blocks insulin's effects on muscle glucose uptake and glycogen storage.</p>Fórmula:C140H227N43O43Pureza:98%Cor e Forma:SolidPeso molecular:3200.61β-CGRP, human
CAS:<p>β-CGRP, human ,a 37-amino acid peptide,is the beta form of Calcitonin-gene-related peptide (β-CGRP), involved extensively in regulation of the cardiovascular</p>Fórmula:C162H267N51O48S3Pureza:98%Cor e Forma:SolidPeso molecular:3793.41Hemokinin 1 (mouse)
CAS:<p>Hemokinin 1 (mouse) is a selective excitogen 1 receptor agonist with a Ki value of 0.175 nM for the human NK1 receptor and 560 nM for the human NK2 receptor.</p>Fórmula:C61H100N22O15SPureza:98%Cor e Forma:White PowderPeso molecular:1413.65Lys-[Des-Arg9]Bradykinin
CAS:Selective bradykinin B1 agonist with Ki 0.12 nM; inactive at B2 (>30,000 nM). Lowers blood pressure, more potent than Des-Arg9-Bradykinin.Fórmula:C50H73N13O11Pureza:98%Cor e Forma:SolidPeso molecular:1032.21YM 16638
CAS:<p>YM 16638 is an LT antagonist that can be used to study antigen-induced early and late airway responses in allergic sheep.</p>Fórmula:C18H22N2O5S3Pureza:99.18%Cor e Forma:SolidPeso molecular:442.57Lanepitant
CAS:<p>Lanepitant (LY303870) is a non-peptide neurokinin-1 (NK-1) antagonist with analgesic activity for the prevention of migraine.</p>Fórmula:C33H45N5O3Pureza:97.71%Cor e Forma:SolidPeso molecular:559.74PG 106 acetate
<p>PG 106 acetate: Selective hMC3 receptor antagonist, IC50=210 nM; inactive on hMC5 and hMC4, EC50=9900 nM.</p>Fórmula:C53H73N13O11Pureza:98.24%Cor e Forma:SolidPeso molecular:1068.23MrgprX2 antagonist-4
CAS:<p>MrgprX2 antagonist-4, from patent US20210128561A1, inhibits MrgprX2 receptor; useful for skin inflammation studies.</p>Fórmula:C16H19N3OCor e Forma:SolidPeso molecular:269.348(+)-Dropropizine
CAS:<p>(+)-Dropropizine can inhibit histamine receptor, anti-allergic, and reduce a cough by modulation of neuropeptides involved in the cough reflex.</p>Fórmula:C13H20N2O2Pureza:>99.99%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:236.31[Ala1,3,11,15]-Endothelin
CAS:<p>Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).</p>Fórmula:C109H163N25O32SPureza:98%Cor e Forma:SolidPeso molecular:2368Tebufelone
CAS:<p>Tebufelone is a potent NSAID, inhibits CO, has anti-inflammatory and analgesic properties, and blocks lipoxygenase products (IC50 ~20-22 microM).</p>Fórmula:C20H28O2Pureza:99.32%Cor e Forma:SolidPeso molecular:300.44Synephrine hemitartrate
CAS:<p>Synephrine hemitartrate, an alkaloid from Citrus aurantium, is a sympathomimetic for weight loss, with α and β-adrenergic action.</p>Fórmula:C9H13NO2C4H6O6Cor e Forma:SolidPeso molecular:242.26Tizanidine
CAS:<p>Tizanidine, an α2-adrenergic receptor agonist, suppresses the release of neurotransmitters from central nervous system (CNS) noradrenergic neurons.</p>Fórmula:C9H8ClN5SPureza:99.11%Cor e Forma:White SolidPeso molecular:253.71Linaclotide acetate
CAS:<p>Linaclotide acetate, an oral guanylate cyclase C agonist with 14 amino acids, treats constipation-predominant IBS and chronic constipation.</p>Fórmula:C61H83N15O23S6Pureza:98%Cor e Forma:SolidPeso molecular:1586.79α-helical CRF 9-41 acetate
<p>α-helical CRF 9-41 acetate is a competitive antagonist of CRF2 (KB = 100 nM) and a partial agonist of CRF1 (EC50 = 140 nM).</p>Pureza:96.60%Cor e Forma:SolidPeso molecular:#N/AGalanin (1-15) (porcine, rat)
CAS:<p>N-terminal galanin fragment used to mediate central cardiovascular effects</p>Fórmula:C72H105N19O20Pureza:98%Cor e Forma:SolidPeso molecular:1556.72PD 144418 oxalate
CAS:<p>PD 144418 oxalate: σ1 receptor ligand, Ki=0.08 nM; 1377 nM for σ2, minimal affinity elsewhere; potential antipsychotic.</p>Fórmula:C20H24N2O5Pureza:98.76%Cor e Forma:SolidPeso molecular:372.42BAY-6672 hydrochloride
CAS:BAY-6672 hydrochloride is a potent, selective antagonist of the human Prostaglandin F (FP) receptor, exhibiting an IC50 value of 11 nM.Fórmula:C26H28BrCl2N3O3Cor e Forma:SolidPeso molecular:581.33Tiflucarbine
CAS:<p>Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of soluble</p>Fórmula:C16H17FN2SPureza:>99.99%Cor e Forma:SolidPeso molecular:288.3815(S)-15-methyl Prostaglandin E2
CAS:<p>15(S)-15-methyl PGE2: A stable PGE2 analog; strong antiulcer with double PGE2 affinity; excels PGE1 in uterine contraction.</p>Fórmula:C21H34O5Cor e Forma:SolidPeso molecular:366.49ONO-0300302
CAS:ONO-0300302: LPA1 antagonist, treats Benign Prostatic Hyperplasia, IC50 = 0.16 nM, reduces IUP in rats and dogs for 12h.Fórmula:C29H35NO5Pureza:98%Cor e Forma:SolidPeso molecular:477.59Terazosin dimer impurity dihydrochloride
CAS:<p>Terazosin dimer impurity dihydrochloride is a chemical byproduct of the α1-antagonist Terazosin, derived from quinazoline.</p>Fórmula:C24H30Cl2N8O4Cor e Forma:SolidPeso molecular:565.46Femoxetine
CAS:<p>Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.</p>Fórmula:C20H25NO2Pureza:99.1% - 99.35%Cor e Forma:SolidPeso molecular:311.42SB656104
CAS:<p>SB656104 is a bioactive chemical.</p>Fórmula:C25H30ClN3O3SCor e Forma:SolidPeso molecular:488.04Brexpiprazole S-oxide D8
CAS:<p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>Fórmula:C25H19D8N3O3SPureza:98%Cor e Forma:SolidPeso molecular:457.61Vortioxetine D8
CAS:<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Fórmula:C18H22N2SPureza:98%Cor e Forma:SolidPeso molecular:306.5Thrombin Receptor Activator for Peptide 5 (TRAP-5)
CAS:<p>Thrombin Receptor Activator for Peptide 5 (TRAP-5) is also called Coagulation Factor II Receptor (1-5), used in the research of coronary heart disease (CHD).</p>Fórmula:C30H50N8O7Pureza:98%Cor e Forma:SolidPeso molecular:634.77GLI1-IN-3
<p>GLI1-IN-3 (Compound 11a) is a triterpenoid-like compound that inhibits Hedgehog signaling in cancer cells with GLI1 overexpression. It suppresses the proliferation of non-small cell lung cancer and prostate cancer cell lines with excessive Hh signaling activation. Additionally, GLI1-IN-3 reduces the expression of GLI1 protein and its target genes associated with tumor progression and proliferation in A549 and DU-145 cancer cells.</p>Cor e Forma:Odour Solid(S)-V-0219 hydrochloride
<p>(S)-V-0219 hydrochloride, a GLP-1R PAM, triggers calcium in hGLP-1R HEK cells, lowers glucose in mice, and reduces fasting hunger.</p>Fórmula:C20H26ClF3N4O2Cor e Forma:SolidPeso molecular:446.89ONO-8711
CAS:<p>ONO-8711 is a potent and selective competitive antagonist of EP1 receptor with Kis of 0.6 nM and 1.7 nM for human and mouse EP1, respectively.</p>Fórmula:C22H30ClNO4SCor e Forma:SolidPeso molecular:440NF 340
CAS:<p>P2Y11 antagonist</p>Fórmula:C37H30N4Na4O15S4Pureza:98%Cor e Forma:SolidPeso molecular:990.87GRK2i
CAS:GRK2 inhibitory polypeptide that specifically inhibits Gβγ activation of GRK2. Corresponds to the Gβγ-binding domain and acts as a cellular Gβγ antagonist.Fórmula:C153H256N50O41SPureza:98%Cor e Forma:SolidPeso molecular:3484.08Surfagon
CAS:Surfagon is an effective LHRH agonist.Fórmula:C56H78N16O12Pureza:98%Cor e Forma:SolidPeso molecular:1167.34Alosetron
CAS:<p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>Fórmula:C17H18N4OPureza:98%Cor e Forma:Crystalline PowderPeso molecular:294.36Bay 55-9837
CAS:<p>Selective VPAC2 agonist; EC50: 0.4 nM (VPAC2), 100 nM (VPAC1), >1000 nM (PAC1). Enhances insulin secretion, reduces HIV-1 replication.</p>Fórmula:C167H270N52O46Pureza:98%Cor e Forma:SolidPeso molecular:3742.29Cetirizine methyl ester
CAS:<p>Cetirizine methyl ester is a Cetirizine impurity, a long-acting, oral H1-antihistamine and hydroxyzine metabolite.</p>Fórmula:C22H27ClN2O3Cor e Forma:SolidPeso molecular:402.91RF9
CAS:<p>RF9 is an effective and selective antagonist of the Neuropeptide FF receptor (Kis: 58±5 and 75±9 nM for hNPFF1R and hNPFF2R, respectively).</p>Fórmula:C26H38N6O3Pureza:98%Cor e Forma:SolidPeso molecular:482.62Apraglutide
CAS:Apraglutide (FE 203799 is a synthetic 33-amino acid peptide and long-acting glp-2 analogue.Fórmula:C172H263N43O52Pureza:98%Cor e Forma:SolidPeso molecular:3765.25Pasireotide ditrifluoroacetate
<p>Pasireotide is a stable cyclohexapeptide somatostatin mimic.</p>Fórmula:C62H68F6N10O13Pureza:98%Cor e Forma:SolidPeso molecular:1275.25Clomipramine D3
CAS:<p>Clomipramine D3 is deuterium-labeled Clomipramine, blocking serotonin, norepinephrine, dopamine transporters (Ki: 0.14, 54, 3 nM).</p>Fórmula:C19H23ClN2Pureza:98%Cor e Forma:SolidPeso molecular:317.8716-phenoxy tetranor Prostaglandin F2α methyl ester
CAS:<p>Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor.</p>Fórmula:C23H32O6Cor e Forma:SolidPeso molecular:404.503CCG258208 hydrochloride
<p>GRKs-IN-1 HCl (14as) strongly inhibits GRK2 (IC50=130nM) & GRK5 (IC50=7.1μM), is a paroxetine derivative with 100x cardiac boost.</p>Cor e Forma:SolidAMI-193
CAS:<p>AMI-193 (Spiramide) is a selective 5-HT2 & D2 receptor antagonist with antipsychotic properties.</p>Fórmula:C22H26FN3O2Pureza:99.65%Cor e Forma:SolidPeso molecular:383.46SR-31747 free base
CAS:<p>SR-31747: immunosuppressive anti-inflammatory agent, inhibits cell growth by blocking sterol isomerase.</p>Fórmula:C23H34ClNCor e Forma:SolidPeso molecular:359.98[Des-Arg9]-Bradykinin acetate
CAS:<p>[Des-Arg9]-Bradykinin acetate is a selective agonist of Bradykinin B1 receptor.</p>Fórmula:C46H65N11O12Pureza:99.05%Cor e Forma:SolidPeso molecular:964.074-Methylhistamine
CAS:<p>4-Methylhistamine serves as a potent agonist for the histamine 4 receptor (H4R), holding promise for research into immune-related diseases, including cancer and</p>Fórmula:C6H11N3Pureza:98%Cor e Forma:SolidPeso molecular:125.17GI-560192
CAS:<p>GI-560192 (RL-0070933), a potent smo modulator, EC50: 0.02µM; affects smoothened in cilia via hedgehog signaling.</p>Fórmula:C20H16N2O2Pureza:99.53%Cor e Forma:SoildPeso molecular:316.35NXT-10796
<p>NXT-10796 is an orally active, intestinally restricted agonist of the EP4 receptor [1].</p>Fórmula:C23H31N3O6Pureza:98%Cor e Forma:SolidPeso molecular:445.51A6770
CAS:<p>A6770 inhibits S1P lyase, causing [3H]dhS1P build-up in IT-79MTNC3 cells (EC50 <0.01 μM); less effective with vitamin B6 (EC50 <100 μM).</p>Fórmula:C6H8N2O2Cor e Forma:SolidPeso molecular:140.142Nastorazepide hemicalcium
CAS:<p>Nastorazepide (Z-360) hemicalcium is a selective, orally-administered 1,5-benzodiazepine derivative that functions as a receptor antagonist for gastrin/cholecystokinin 2 (CCK-2), exhibiting potential antitumor activity.</p>Fórmula:C29H36N4O5CaCor e Forma:SolidPeso molecular:540.66Dexbrompheniramine maleate
CAS:<p>Dexbrompheniramine is an antihistamine used for hay fever and urticaria, blocking H1 receptors in the body.</p>Fórmula:C20H23BrN2O4Cor e Forma:SolidPeso molecular:435.3185-HT1AR agonist 2
<p>5-HT1AR Agonist 2 (Compound 4f) is a potent agonist of the 5-HT1A receptor with a Ki value of 10.0 nM. It also binds to SERT, D2, and 5-HT6 receptors with Ki values of 2.8 nM, 23 nM, and 192 nM, respectively. Furthermore, this compound demonstrates stability in microsomes and induces hypothermia in mice.</p>Fórmula:C31H31N5O3Cor e Forma:SolidPeso molecular:521.61Boc-Phe-Leu-Phe-Leu-Phe
CAS:<p>Boc-Phe-Leu-Phe-Leu-Phe is a chemotactic peptide antagonist that inhibits the release of peptide leukotrienes induced by FMLP.</p>Fórmula:C44H59N5O8Cor e Forma:SolidPeso molecular:785.97MRS7925
<p>MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosis</p>Fórmula:C20H26IN5O3Pureza:98%Cor e Forma:SolidPeso molecular:511.36FGH31
<p>FGH31 (Compound 24), a dopamine D4 agonist, exhibits potent and selective GRK2-dependency with a K i of 1.6 nM and partially activates β-arrestin [1].</p>Fórmula:C33H36N4O2Pureza:98%Cor e Forma:SolidPeso molecular:520.66Bradykinin (1-7)
CAS:<p>Bradykinin (1-7), an amino-truncated peptide derived from Bradykinin, is a metabolite formed through enzymatic cleavage by endopeptidase.</p>Fórmula:C35H52N10O9Pureza:98%Cor e Forma:White Lyophilized PowderPeso molecular:756.85CB2R agonist 3
<p>CB2R agonist 3, a potent activator of cannabinoid receptor 2 (CB2R), exhibits an EC50 value of 0.37μM, indicative of its significant role in the immune system [</p>Pureza:98%Cor e Forma:Odour SolidN-Desmethyl Pimavanserin
CAS:<p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>Fórmula:C24H32FN3O2Pureza:98.02%Cor e Forma:SolidPeso molecular:413.53Luseogliflozin
CAS:<p>Luseogliflozin inhibits SGLT2 for glucose uptake with 1.10 nM potency.</p>Fórmula:C23H30O6SCor e Forma:SolidPeso molecular:434.5515(R)-17-phenyl trinor Prostaglandin F2α
CAS:<p>17-phenyl trinor Prostaglandin F2α N-ethyl amide (17-phenyl trinor PGF2α) is an F-series prostaglandin analog which has been approved for use as an ocular</p>Fórmula:C23H32O5Cor e Forma:SolidPeso molecular:388.5LHRH
CAS:<p>Luteinizing hormone-releasing hormone (LHRH) is a neuropeptide produced in the hypothalamus that plays a pivotal role in regulating reproduction and has</p>Fórmula:C55H74N16O14Pureza:98%Cor e Forma:SolidPeso molecular:1183.27TT-OAD2
CAS:<p>TT-OAD2 is a non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor (EC50: 5 nM), with the potential for diabetes treatment.</p>Fórmula:C50H49Cl4N3O6Pureza:98%Cor e Forma:SolidPeso molecular:929.75human GALP (3-32)
<p>Human GALP (3-32) (Galanin-like peptide (3-32)) serves as a high-affinity agonist for galanin receptors GalR1 (IC50 = 33 nM) and GalR2 (IC50 = 15 nM), as</p>Fórmula:C137H213N43O38SPureza:98%Cor e Forma:SolidPeso molecular:3102.49Bim 21009
CAS:Bim 21009 is an inhibitor of gonadorelin.Fórmula:C74H92ClN17O13Pureza:98%Cor e Forma:SolidPeso molecular:1463.08Adenosine receptor antagonist 1
CAS:<p>A2aR-selective antagonist with IC50 of 0.29 nM; 14x more selective over A2bR.</p>Fórmula:C22H15ClFN7OCor e Forma:SolidPeso molecular:447.865-HT6 agonist 1
Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting plateletFórmula:C17H22Cl2N6SPureza:98%Cor e Forma:SolidPeso molecular:413.37ELA-11(human)
CAS:<p>Apelin receptor agonist with high affinity (Ki = 14 nM). Blocks cAMP production and promotes β-arrestin activation; derived from ELA-32.</p>Fórmula:C58H90N16O13S2Pureza:98%Cor e Forma:SolidPeso molecular:1283.57GLP-1R agonist 14
CAS:<p>GLP-1R agonist 14, also known as Compound 14, is a potent agonist of the GLP-1 receptor, demonstrating an EC50 range of 0-20 nM against human GLP-1 [1].</p>Fórmula:C45H42F2N10O5Cor e Forma:SolidPeso molecular:840.88AB21 oxalate
<p>AB21 oxalate, a potent and selective S1R antagonist, exhibits binding affinities (Kis) of 13 nM and 102 nM for S1R and S2R, respectively.</p>Fórmula:C25H30N2O5Pureza:98%Cor e Forma:SolidPeso molecular:438.52FXR/TGR5 agonist 1
CAS:<p>FXR/TGR5 agonist 1 acts as an agonist on both FXR and TGR5 receptors and is utilized for treating fatty liver disease.</p>Fórmula:C31H32ClN3O3Cor e Forma:SolidPeso molecular:530.07M617
CAS:<p>Galanin GAL1 agonist, Ki: GAL1 0.23 nM, GAL2 5.71 nM; boosts rat appetite, lessens inflammation pain.</p>Fórmula:C112H161N29O28Pureza:98%Cor e Forma:SolidPeso molecular:2361.68Bz-Dab(nbd)-awfpp-nle-NH2
CAS:<p>Bz-Dab(nbd)-ala-trp-phe-pro-pro-nle-NH2 is a fluorescent NK2 antagonist.</p>Fórmula:C56H65N13O11Cor e Forma:SolidPeso molecular:1096.2Gulgafafusp alfa
CAS:<p>Gulgafafusp alfa is a human IgG2κ monoclonal antibody that selectively binds to the glucagon-like peptide 1 receptor (GLP1R) [1].</p>Cor e Forma:LiquidMuscarinic toxin 3
CAS:<p>Muscarinic toxin 3 (MT3), a potent non-competitive antagonist of mAChR and adrenoceptors, exhibits pIC50 values of 6.71 for M1, 8.79 for M4, 8.86 for α1A, 7.57</p>Fórmula:C319H489N89O97S8Pureza:98%Cor e Forma:SolidPeso molecular:7379.35PSB-1114 triethylamine
<p>PSB-1114 triethylamine is a potent, enzymatically stable, P2Y2 receptor agonist with a 134 nM EC50, exhibiting greater than 50-fold selectivity over P2Y4 (EC50</p>Fórmula:C10H15F2N3O13P3S·xC6H15NPureza:98%Cor e Forma:Solidα-CGRP (mouse, rat) TFA
<p>α-CGRP (mouse, rat) TFA, a neuropeptide belonging to the calcitonin gene-related peptide (CGRP) family, is predominantly located at neuromuscular junctions and</p>Fórmula:C162H262N50O52S2·C2HF3O2Pureza:98%Cor e Forma:SolidAdatanserin hydrochloride
CAS:<p>Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.</p>Fórmula:C21H32ClN5OPureza:99.64%Cor e Forma:SolidPeso molecular:405.96Emoghrelin
CAS:<p>Emoghrelin, extracted from Heshouwu (Polygonum multiflorum), promotes the secretion of growth hormone by activating the ghrelin receptor [1].</p>Fórmula:C24H22O13Pureza:98%Cor e Forma:SolidPeso molecular:518.42PACAP (6-38), human, ovine, rat
CAS:<p>PACAP (6-38) in humans, sheep, rats: a strong inhibitor of PACAP 38, outperforms PACAP (6-27) in blocking PACAP-27-induced adenylate cyclase.</p>Fórmula:C182H300N56O45SPureza:98%Cor e Forma:SolidPeso molecular:4024.74[Ala11,D-Leu15]-Orexin B(human)
CAS:<p>OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).</p>Fórmula:C120H206N44O35SPureza:98%Cor e Forma:SolidPeso molecular:2857.28Substance P (1-9)
CAS:<p>Substance P (1-9), a nonapeptide, slows its own inactivation and stimulates neurons.</p>Fórmula:C52H77N15O12Pureza:98%Cor e Forma:SolidPeso molecular:1104.26CRF(6-33)(human)
CAS:<p>CRFBP inhibitor peptide; blocks CRF, reduces weight gain, boosts activity in obese rats.</p>Fórmula:C141H231N41O43SPureza:98%Cor e Forma:SolidPeso molecular:3220.68FFN246
CAS:<p>FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and</p>Fórmula:C15H13FN2OPureza:98%Cor e Forma:SolidPeso molecular:256.27Oxmetidine FA
<p>Oxmetidine FA is an orally available specific histamine H2 receptor antagonist with antiulcerogenic properties.</p>Fórmula:C20H23N5O5SPureza:97.34%Cor e Forma:SoildPeso molecular:445.49Latanoprost tris(triethylsilyl) ether
CAS:<p>Latanoprosttris(triethylsilyl) ether is a precursor in the synthesis of Latanoprost, which serves as an agonist for the prostaglandin F2α (PGF2α) receptor, also known as the FP receptor.</p>Fórmula:C44H82O5Si3Cor e Forma:SolidPeso molecular:775.38APP-FUBINACA
CAS:<p>APP-FUBINACA is a cannabinoid receptor agonist, classified as a phenylalanine amide-based indazole-3-carboxamide derivative. It exhibits neurostimulatory effects.</p>Fórmula:C24H21FN4O2Cor e Forma:SolidPeso molecular:416.45hA3AR agonist 2
<p>hA3AR agonist 2 is a potent activator of A3AR, with a Ki value of 3.5 nM.</p>Fórmula:C11H14ClN5O2SCor e Forma:SolidPeso molecular:315.78Lanepitant 2HCl
CAS:<p>Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist that can be used to study painful neuropathy-like disorders such as migraine.</p>Fórmula:C33H47Cl2N5O3Pureza:98.67%Cor e Forma:SolidPeso molecular:632.664-Bromo-2,5-DMMA
CAS:<p>4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.</p>Fórmula:C12H18BrNO2Cor e Forma:SolidPeso molecular:288.18Methicillin sodium hydrate
CAS:<p>Methicillin sodium hydrate, a narrow-spectrum antibiotic, combats methicillin-resistant Staphylococcus strains and treats various infections.</p>Fórmula:C17H21N2NaO7SCor e Forma:SolidPeso molecular:420.41O-Desethyl Dapagliflozin
CAS:<p>O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.</p>Fórmula:C19H21ClO6Pureza:98.33%Cor e Forma:SolidPeso molecular:380.82Δ8-THC-C8
CAS:<p>Δ8-THC-C8 is a semi-synthetic cannabinoid. It acts as an agonist for the cannabinoid receptor 1 (CB1) with an EC50 value of 13.8 nM.</p>Fórmula:C24H36O2Cor e Forma:SolidPeso molecular:356.54GLP-1R agonist 4
CAS:<p>GLP-1R agonist 4, potentially for diabetes research, is a potent GLP-1R stimulator linked to hypoglycemia.</p>Fórmula:C32H30ClF2N3O5Cor e Forma:SolidPeso molecular:610.0525N-NBOMe hydrochloride
CAS:<p>25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.</p>Fórmula:C18H23ClN2O5Cor e Forma:SolidPeso molecular:382.845-MeO-MET
CAS:<p>5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.</p>Fórmula:C14H20N2OCor e Forma:SolidPeso molecular:232.32Sufotidine
CAS:<p>Sufotidine (AH 25352X) is a highly selective competitive H2 receptor antagonist.</p>Fórmula:C20H31N5O3SPureza:99.03% - 99.92%Cor e Forma:SolidPeso molecular:421.56Eloralintide
CAS:<p>Eloralintide (LY 3841136) is an AMYR agonist, anticipated for research in type 2 diabetes and obesity.</p>Fórmula:C201H319N49O65S2Cor e Forma:SolidPeso molecular:4526.1Prostaglandin D2 methyl ester
CAS:<p>PGD2: made in mast cells during allergic reactions, causes vasodilation and inhibits blood clots. PGD2 methyl ester is a similar, fat-soluble prodrug.</p>Fórmula:C21H34O5Cor e Forma:SolidPeso molecular:366.498L-797,591
CAS:<p>L-797,591 is a selective agonist of somatostatin receptor subtype 1.</p>Fórmula:C38H49N5O2Cor e Forma:SolidPeso molecular:607.8317-TFM-PGF1α
CAS:<p>17-TFM-PGF1α (Compound 8) is a saturated prostaglandin analog. It exhibits a high affinity and receptor selectivity for the human prostaglandin F receptor (hFP receptor), with an EC50 of 85 nM.</p>Fórmula:C24H35F3O5Cor e Forma:SolidPeso molecular:460.53LY 293284
CAS:<p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>Fórmula:C19H26N2OCor e Forma:SolidPeso molecular:298.426-Fluoro-N,N-diethyltryptamine
CAS:<p>6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.</p>Fórmula:C14H19FN2Cor e Forma:SolidPeso molecular:234.31Fasitibant chloride hydrochloride
CAS:<p>Fasitibant chloride( MEN16132) is an effective and selective non-peptide antagonist of kinin B2 receptor.</p>Fórmula:C36H50Cl4N6O6SCor e Forma:SolidPeso molecular:836.7GLP-1(28-36)amide acetate
<p>GLP-1(28-36)amide acetate inhibits mitochondrial permeability transition with antioxidant, anti-diabetic and cardioprotection activities.</p>Fórmula:C56H89N15O11Pureza:99.9500%Cor e Forma:SolidPeso molecular:1148.4MLN-3897 TFA
<p>MLN-3897 TFA is a potent CCR1 antagonist that inhibits the binding of 125I-MIP-1α to THP-1 cell membranes.</p>Fórmula:C32H32ClF3N2O6Pureza:98.62%Cor e Forma:SolidPeso molecular:633.05RFRP-1(human)
CAS:<p>Endogenous NPFF agonist with EC50 of 0.0011 nM (NPFF2) and 29 nM (NPFF1); reduces cardiac function and raises prolactin in rats. GnIH homolog.</p>Fórmula:C67H101N19O14SPureza:98%Cor e Forma:SolidPeso molecular:1428.72DOTA-LM3 TFA
<p>DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist with the molecular structure p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2.</p>Fórmula:C71H94ClF3N16O21S2Cor e Forma:SolidPeso molecular:1664.18Casopitant
CAS:<p>Casopitant (GW679769) is an orally active neurokinin-1 (NK1) receptor antagonist, researched for its potential use in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV).</p>Fórmula:C30H35F7N4O2Cor e Forma:SolidPeso molecular:616.61PG106 TFA
<p>PG106 TFA is a potent hMC3 antagonist (IC50=210 nM), inactive at hMC4 (EC50=9900 nM) and hMC5 receptors.</p>Fórmula:C53H70F3N13O11Cor e Forma:SolidPeso molecular:1122.2GHRF, porcine
CAS:<p>GHRF, porcine, a growth hormone releasing factor (GHRF) peptide (porcine), binds to the growth hormone secretagogue receptor (GHSR), thereby inducing the</p>Fórmula:C219H365N73O66SCor e Forma:SolidPeso molecular:5108.76α-Helical CRF(9-41) TFA
<p>α-Helical CRF(9-41) TFA acts as a competitive antagonist for the CRF2 receptor, possessing a binding constant (K B) of approximately 100 nM.</p>Fórmula:C168H275F3N46O55S2Cor e Forma:SolidPeso molecular:3940.42Corazonin
CAS:<p>Corazonin, a neuropeptide in insects, regulates caste identity and behavior, mainly in workers/foragers.</p>Fórmula:C62H83N17O19Cor e Forma:SolidPeso molecular:1370.42dCNP
<p>dCNP binds to NPR-B/C receptors (NPR-B/C receptor), initiating the cGMP signaling pathway and regulating vascular function. It exhibits anti-hypoxic effects by downregulating hypoxia-related genes such as HIF1α and HIF2α. Additionally, dCNP inhibits tumor stroma induction, demonstrating antifibrotic properties. It also enhances immune response by upregulating CTL, NK cells, and conventional type 1 dendritic cells in tumors.</p>Fórmula:C141H248N38O36S3Cor e Forma:SolidPeso molecular:3147.91Neurokinin Receptor (393-407), rat
CAS:<p>Rat NK1R fragment (393-407) binds SP, enabling endocytosis and plasma membrane recycling; key in neurogenic inflammation research.</p>Fórmula:C72H113N17O26S2Cor e Forma:SolidPeso molecular:1696.9[His1,Nle27] GHRF (1-32), amide, human
CAS:<p>[His1,Nle27] GHRF (1-32), amide, human is a potent GHRH analog with high GHRHR affinity.</p>Fórmula:C159H265N51O46Cor e Forma:SolidPeso molecular:3627.12ANP [Des18-22] 4-23 amide rat
CAS:<p>ANP [Des18-22] 4-23 amide rat is a peptide fragment of rat atrial natriuretic peptide (ANP) that specifically binds to NPR-C.</p>Fórmula:C64H107N25O19S2Cor e Forma:SolidPeso molecular:1594.82Selepressin acetate
<p>Selepressin acetate is a useful organic compound for research related to life sciences and the catalog number is T73654.</p>Fórmula:C48H77N13O13S2Cor e Forma:SolidPeso molecular:1108.33[Ala2] Endothelin-3, human
CAS:<p>[Ala2] Endothelin-3, a linear ET-3 analog with Ala replacing Cys, stimulates endothelial cell migration.</p>Fórmula:C120H166N26O32S4Cor e Forma:SolidPeso molecular:2613.02Dotanoc
CAS:<p>Dotanoc is a ligand to make gallium Ga 68-DOTANOC, which is a gallium Ga 68-radiolabeled analog of somatostatin.</p>Fórmula:C69H94N14O17S2Cor e Forma:SolidPeso molecular:1455.71Gastrin I, rat
CAS:<p>Gastrin I, rat is a peptide hormone that effectively stimulates gastric acid secretion.</p>Fórmula:C94H128N22O31S2Cor e Forma:SolidPeso molecular:2126.3Neuropeptide Y (3-36) (porcine)
CAS:<p>Neuropeptide Y (3-36) (porcine) is a potent, selective agonist at NPY Y2 receptors, increasing feeding in rats.</p>Fórmula:C176H271N53O54Cor e Forma:SolidPeso molecular:3993.36TAK-683 acetate
<p>TAK-683 acetate: potent KISS1R agonist (IC50=170 pM), stable, nonapeptide. Affects GnRH, FSH, LH, testosterone; potential in prostate cancer research.</p>Fórmula:C66H87N17O15Cor e Forma:SolidPeso molecular:1358.5Baloncibart
CAS:<p>Baloncibart is a human IgG4K monoclonal antibody that targets NPR1.</p>Cor e Forma:LiquidAcetyl-Amylin (8-37) (human)
CAS:<p>Acetyl-Amylin (8-37) (human) is a specific amylin antagonist [1] .</p>Fórmula:C140H218N42O46Cor e Forma:SolidPeso molecular:3225.48Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide
<p>Biotin-labeled GLP-1-(7-36) amide; a gut peptide that enhances insulin release.</p>Fórmula:C165H252N44O48SCor e Forma:SolidPeso molecular:3652.1Atilmotin
CAS:<p>Atilmotin is a gastrointestinal agent for treating motility disorders.</p>Fórmula:C86H135N20O19Cor e Forma:SolidPeso molecular:1753.146MM 419447
CAS:<p>MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist showing potential in IBS-C research.</p>Fórmula:C50H70N14O19S6Cor e Forma:SolidPeso molecular:1363.55(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
CAS:<p>(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a corticotropin-releasing factor (CRF) antagonist known to counteract the inhibitory effects of IL-1a</p>Fórmula:C159H267N49O43Cor e Forma:SolidPeso molecular:3553.12Prepro-ANF (56-92), human
CAS:<p>Human prepro-ANF (56-92) activates renal guanylate cyclase and boosts its activity.</p>Fórmula:C173H270N44O57Cor e Forma:SolidPeso molecular:3878.26Protease-Activated Receptor-1, PAR-1 Agonist TFA
<p>PAR-1 Agonist TFA: Selective peptide, mimics thrombin, activates PAR-1 receptor.</p>Cor e Forma:Liquid(Trp7,β-Ala8)-Neurokinin A (4-10)
CAS:<p>(Trp7,β-Ala8)-Neurokinin A (4-10) is a potent neurokinin-3 (NK3) antagonist [1] .</p>Fórmula:C41H57N9O10SCor e Forma:SolidPeso molecular:868.01Cyclosomatostatin TFA
<p>Cyclosomatostatin TFA blocks SST receptor, reduces CRC cell growth, ALDH+ size, and sphere-formation.</p>Fórmula:C46H58F3N7O8Cor e Forma:SolidPeso molecular:893.99Sauvagine TFA
<p>Sauvagine TFA: frog-derived, 40-amino-acid CRF agonist; stimulates ACTH release, affects diuresis, cardiovascular system, endocrine glands.</p>Fórmula:C204H347F3N56O65S1Cor e Forma:SolidPeso molecular:4713.33Melatonin-Tamoxifen Conjugate
<p>Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.</p>Fórmula:C47H58N4O4Cor e Forma:SolidPeso molecular:742.99V1a/V2 antagonist 1
<p>V1a/V2 antagonist 1 (Compound 18j) is an orally active dual-target antagonist of V1a and V2 receptors, exhibiting high binding affinity toward these receptors [Ki values are hV1a: 0.13 nM, hV2: 0.53 nM, and mV1a: 0.5 nM; IC50 for hV1a is 2.2 nM]. This compound can inhibit oxytocin-induced scratching behavior in mice.</p>Fórmula:C25H26ClN5O3Cor e Forma:SolidPeso molecular:479.96(Phe2,Orn8)-Oxytocin
CAS:<p>(Phe2,Orn8)-Oxytocin: Selective V1 agonist, induces rabbit epididymis contractility, EC50=280 nM.</p>Fórmula:C42H65N13O11S2Cor e Forma:SolidPeso molecular:992.18AC 187 TFA
<p>AC 187 TFA, a potent and orally active amylin receptor antagonist, exhibits an IC50 of 0.48 nM and a Ki of 0.275 nM.</p>Fórmula:C129H206F3N37O42Cor e Forma:SolidPeso molecular:3004.2725E-NBOMe hydrochloride
CAS:<p>25E-NBOMe hydrochloride is a derivative of 2C-E, featuring an N-(2-methoxybenzyl) addition to the amine group, and acts as a selective agonist of the 5-HT2A receptor.</p>Fórmula:C20H28ClNO3Cor e Forma:SolidPeso molecular:365.89Kisspeptin-10, rat TFA
<p>Kisspeptin-10, a rat TFA, constricts blood vessels, inhibits vessel growth, and counters Methotrexate reproductive toxicity.</p>Fórmula:C65H84F3N17O17Cor e Forma:SolidPeso molecular:1432.46Guanylin(human) TFA
<p>Guanylin (human) TFA, a 15-amino acid peptide, activates intestinal guanylate cyclase, regulating electrolyte and water transport via cGMP.</p>Cor e Forma:Liquida-Helical Corticotropin Releasing Factor (12-41)
CAS:<p>α-Helical CRF (12-41), a 30-aa analog, curbs CRF's ACTH-stimulating effect.</p>Fórmula:C152H251N43O47S2Cor e Forma:SolidPeso molecular:3497.01Cortistatin 29
<p>Cortistatin 29: neuropeptide, relieves neuropathic pain, binds SS receptors (IC50: 2.8-13.7 nM), anti-fibrotic.</p>Fórmula:C161H242N46O41S2Cor e Forma:SolidPeso molecular:3539.77Calcitonin Gene Related Peptide (CGRP) II, rat TFA
<p>Rat CGRP II TFA: potent vasodilator and CGRP receptor activator for cardiovascular research.</p>Fórmula:C165H268F3N51O52S2Cor e Forma:SolidPeso molecular:3919.33Neuropeptide S(Mouse) TFA
<p>Neuropeptide S(Mouse) TFA: Endogenous NPSR agonist, EC50 3 nM, boosts Ca2+, activity, wakefulness, and lowers mouse anxiety.</p>Fórmula:C92H157F3N34O29Cor e Forma:SolidPeso molecular:2296.49Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin
CAS:<p>Desamino(D-3-(3′-pyridyl)-Ala2,Arg8)-Vasopressin, a synthetic analog of vasopressin (AVP), acts as a weak agonist at the antidiuretic receptor but is a potent</p>Fórmula:C45H63N15O11S2Cor e Forma:SolidPeso molecular:1054.21GnRH Associated Peptide (1-24), human
CAS:<p>GnRH Associated Peptide (GAP) (1-24), human, is the 1-24 fragment of hGAP linked to LH-RH via a 3 amino acid site.</p>Fórmula:C117H190N32O43Cor e Forma:SolidPeso molecular:2732.95PAR-2 (1-6) (human)
CAS:<p>PAR-2 (1-6) (human) (SLIGKV), a peptide ligand, is a PAR-2 agonist [1] .</p>Fórmula:C28H53N7O8Cor e Forma:SolidPeso molecular:615.764-Iodoamphetamine hydrochloride
CAS:<p>4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.</p>Fórmula:C9H13ClINCor e Forma:SolidPeso molecular:297.56Exendin-4 (3-39)
CAS:<p>Exendin-4 (3-39) is a truncated peptide missing first 2 amino acids of Exendin-4, a potent GLP-1r agonist used in diabetes and HPA axis research.</p>Fórmula:C176H272N46O58SCor e Forma:SolidPeso molecular:3992.44CKLF1-C27 TFA
<p>CKLF1-C27 peptide activates ERK1/2 via CCR4, competes with CKLF1, promotes HUVEC growth, and has psoriasis research potential.</p>Fórmula:C153H244F3N39O39Cor e Forma:SolidPeso molecular:3310.8sGnRH-A
CAS:<p>sGnRH-A, a salmon GnRH analog, boosts growth hormone and induces ovulation for artificial insemination.</p>Fórmula:C64H83N17O12Cor e Forma:SolidPeso molecular:1282.45(p-Iodo-Phe7)-ACTH (4-10)
CAS:<p>(p-Iodo-Phe7)-ACTH (4-10), an ACTH derivative and MC receptor antagonist, inhibits α-MSH-induced grooming in rats.</p>Fórmula:C44H58IN13O10SCor e Forma:SolidPeso molecular:1087.98α-MSH TFA
CAS:<p>α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the</p>Fórmula:C79H110F3N21O21SCor e Forma:SolidPeso molecular:1778.93Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2
CAS:<p>Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biologically active peptide functioning as a selective agonist for Protease Activated Receptor 1 (PAR-1), a subtype</p>Fórmula:C42H63FN12O8Cor e Forma:SolidPeso molecular:883.02Δ8-THC methyl ether
CAS:<p>Δ8-THC methyl ether (compound 3) demonstrates a strong docking score of -10.167 kcal/mol for the CB2 receptor. Additionally, Δ8-THC methyl ether exhibits antinociceptive activity in mice.</p>Fórmula:C22H32O2Cor e Forma:SolidPeso molecular:328.494-hydroxy DiPT hydrochloride
CAS:<p>4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.</p>Fórmula:C16H25ClN2OCor e Forma:SolidPeso molecular:296.84σ1R-IN-1
σ1R-IN-1 ((R,R)-1a) is an effective σ-1R inhibitor with an IC50 of 110 nM. It shows promising potential for use in research related to neuropsychiatric disorders.Fórmula:C15H22N2Cor e Forma:SolidPeso molecular:230.35SKF-83566 hydrochloride
CAS:<p>SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.</p>Fórmula:C17H19BrClNOPureza:99.27%Cor e Forma:SoildPeso molecular:368.69Rubraxanthone
CAS:<p>Rubraxanthone is a PAF inhibitor isolated from Garcinia parvifolia Miq.</p>Fórmula:C24H26O6Cor e Forma:SolidPeso molecular:410.466GLP-1R Antagonist 1
CAS:<p>GLP-1R Antagonist 1 is an orally active, CNS penetrant and non-competitive glucagon-like peptide 1 receptor (GLP-1R) antagonist (IC50: 650 nM).</p>Fórmula:C16H11ClF6N4O2Pureza:99.84%Cor e Forma:SolidPeso molecular:440.73L-796,778
CAS:<p>L-796,778 is an SST3 agonist and a selective ligand of SST3, which can increase the level of cAMP in the body.</p>Fórmula:C29H40N6O7Pureza:96.20%Cor e Forma:SolidPeso molecular:584.66Latanoprost lactone diol
CAS:Latanoprost lactone diol, a key intermediate for synthesizing Latanoprost (a prostaglandin F2α analogue), lowers IOP by activating FP receptors.Fórmula:C18H24O4Pureza:98%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:304.38Cetirizine Impurity C dihydrochloride
CAS:<p>Cetirizine Impurity C dihydrochloride is a Cetirizine metabolite and long-acting H1-antihistamine.</p>Fórmula:C21H27Cl3N2O3Cor e Forma:SolidPeso molecular:461.81Galanin (1-29)(rat, mouse)
CAS:<p>Non-selective galanin agonist; Ki: GAL1-0.98, GAL2-1.48, GAL3-1.47 nM. Anticonvulsant, stops full seizures in rats.</p>Fórmula:C141H211N43O41Pureza:98%Cor e Forma:White Lyophilized PowderPeso molecular:3164.499GLP-1R Agonist DMB
CAS:<p>GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor).</p>Fórmula:C13H15Cl2N3O2SPureza:99.52%Cor e Forma:SolidPeso molecular:348.25
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