GPCR/Proteína-G
Os inibidores de GPCR/proteínas G são compostos que têm como alvo os receptores acoplados a proteínas G (GPCRs) e as proteínas G associadas, que desempenham papéis críticos na transmissão de sinais do exterior para o interior das células. Esses inibidores são essenciais para estudar as vias de sinalização mediadas por GPCRs, que estão envolvidas em numerosos processos fisiológicos, incluindo percepção sensorial, resposta imunológica e neurotransmissão. Os inibidores de GPCR também são importantes no desenvolvimento de medicamentos, pois muitos agentes terapêuticos têm como alvo esses receptores. Na CymitQuimica, oferecemos uma ampla gama de inibidores de GPCR/proteínas G de alta qualidade para apoiar sua pesquisa em farmacologia, biologia celular e áreas afins.
Subcategorias de "GPCR/Proteína-G"
- Receptor 5-HT(942 produtos)
- Receptor de adenosina(242 produtos)
- Receptor adrenérgico(2.948 produtos)
- Receptor de Bombesina(30 produtos)
- Receptor de Bradicinina(59 produtos)
- CXCR(149 produtos)
- CaSR(32 produtos)
- Receptor de Canabinóides(195 produtos)
- Receptor de Dopamina(409 produtos)
- Receptor Endotelina(75 produtos)
- Receptor GNRH(73 produtos)
- GPCR19(31 produtos)
- GRK(32 produtos)
- GTPase(21 produtos)
- Receptor Glucagon(166 produtos)
- Hedgehog/Smoothened(45 produtos)
- Receptor de Histamina(359 produtos)
- Receptor LPA(21 produtos)
- Receptor de Melatonina(24 produtos)
- Receptor OX(40 produtos)
- Receptor opioide(298 produtos)
- PAFR(11 produtos)
- PKA(49 produtos)
- Receptor S1P(17 produtos)
- SGLT(30 produtos)
- Receptor Sigma(46 produtos)
Exibir 18 mais subcategorias
Foram encontrados 5373 produtos de "GPCR/Proteína-G"
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Apelin-13
CAS:<p>Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor</p>Fórmula:C69H111N23O16SPureza:96.81%Cor e Forma:SolidPeso molecular:1550.83Fenclozine Maleate
CAS:<p>Fenclozine Maleate (S 1429) is a potential histamine H1 receptor antagonist , which can be used to study fever, inflammation and pain.</p>Fórmula:C45H47ClN2O12Pureza:98.47%Cor e Forma:SoildPeso molecular:843.314Risperidone
CAS:<p>Risperidone (R 64 766) is a selective blocker of dopamine D2 receptors and serotonin 5-HT2 receptors that act as an atypical antipsychotic agent.</p>Fórmula:C23H27FN4O2Pureza:99.73%Cor e Forma:Crystalline SolidPeso molecular:410.48JHU 75528
CAS:<p>JHU 75528 (JHU-75528) is a novel PET tracer with inhibitory effects on CB that can be used to study the cannabinoid system in schizophrenic patients.</p>Fórmula:C23H21Cl2N5O2Pureza:99.79%Cor e Forma:SolidPeso molecular:470.35Quercetin-3'-o-phosphate TEA
<p>Quercetin-3'-o-phosphate TEA (Quercetin 3'-phosphate TEA) is an adenosine A receptor antagonist that can be used to prevent and treat metabolic disorders.</p>Fórmula:C21H26NO10PPureza:95.63%Cor e Forma:SoildPeso molecular:483.41Molindone hydrochloride
CAS:<p>Molindone hydrochloride (EN-1733A) is an indole derivative effective in schizophrenia and other psychoses by blocking the effects of dopamine in the brain.</p>Fórmula:C16H24N2O2·HClPureza:99% - 99.99%Cor e Forma:SolidPeso molecular:312.84GTS-21 dihydrochloride
CAS:<p>GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.</p>Fórmula:C19H20N2O2·2HClPureza:98.54% - >99.99%Cor e Forma:SolidPeso molecular:381.3Roluperidone
CAS:<p>Roluperidone (CYR-101) is a novel cyclic amide derivative.</p>Fórmula:C22H23FN2O2Pureza:96.46% - 97.77%Cor e Forma:SolidPeso molecular:366.43ALLO-2
CAS:<p>ALLO-2 is a Inhibitor of Drug-Resistant Smo Mutant.It inhibits Smo agonist Hh-Ag1.5-induced luciferase expression in TM3-Gli-Luc cells with IC50 of 6 nM.</p>Fórmula:C18H12F3N5OPureza:99.19%Cor e Forma:SolidPeso molecular:371.322',5'-Dideoxyadenosine
CAS:<p>2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM).</p>Fórmula:C10H13N5O2Pureza:99.55%Cor e Forma:White SolidPeso molecular:235.24Amisulpride
CAS:<p>Amisulpride (Solian/Deniban), a dopamine antagonist antipsychotic, treats psychosis and schizophrenia in Europe/Australia, not in the US.</p>Fórmula:C17H27N3O4SPureza:99.97%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:369.48MRGPRX1 agonist 1
CAS:<p>MRGPRX1 agonist 1 is a highly potent MRGPRX1 (Mas-related G-protein-coupled receptor X1)agonist(EC50 of 50 nM).</p>Fórmula:C23H21N3O4SPureza:99.95%Cor e Forma:SolidPeso molecular:435.5Azelastine hydrochloride
CAS:<p>Azelastine hydrochloride (Astelin) is a phthalazinone derivative with antihistaminergic activity.</p>Fórmula:C22H24ClN3O·HClPureza:98% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:418.36Ketotifen fumarate
CAS:<p>Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.</p>Fórmula:C23H23NO5SPureza:99.25% - 99.73%Cor e Forma:SolidPeso molecular:425.506-Iodopravadoline
CAS:<p>6-Iodopravadoline (AM630) is an antagonist of CB2 (Ki: 31.2 nM). And it shows 165-fold selectivity more than CB1 receptors.</p>Fórmula:C23H25IN2O3Pureza:99.29%Cor e Forma:Off-White SolidPeso molecular:504.36CYM50308
CAS:<p>CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM).</p>Fórmula:C20H21F2N3O2SPureza:99.43% - 99.77%Cor e Forma:SolidPeso molecular:405.46Tolnaftate
CAS:<p>Tolnaftate (NP-27) is a synthetic antifungal agent.</p>Fórmula:C19H17NOSPureza:98.85%Cor e Forma:White PowderPeso molecular:307.41Fenoterol
CAS:Fenoterol is an agonist of β2-adrenergic receptor It is classed as sympathomimetic beta agonist and asthma medication.Fórmula:C17H21NO4Pureza:98.29%Cor e Forma:SolidPeso molecular:303.35BP 897 hydrochloride
CAS:<p>BP 897: potent D3 agonist (Ki: 0.92 nM), weak D2 antagonist (Ki: 61 nM), low affinity for D1/D4.</p>Fórmula:C26H32ClN3O2Pureza:99.42%Cor e Forma:SolidPeso molecular:454Dapoxetine hydrochloride
CAS:<p>Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.</p>Fórmula:C21H23NO·HClPureza:99.70% - 99.91%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:341.87Ranitidine Hydrochloride
CAS:<p>Ranitidine Hydrochloride (AH19065) is a competitive and reversible inhibitor of histamine H2-receptor antagonists with antacid activity.</p>Fórmula:C13H23ClN4O3SPureza:99.30% - 99.49%Cor e Forma:SolidPeso molecular:350.86Fluphenazine dihydrochloride
CAS:<p>Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR. Fluphenazine can be used to probe effects and metabolic process.</p>Fórmula:C22H28Cl2F3N3OSPureza:99.23%Cor e Forma:Off-White SolidPeso molecular:510.44Evocalcet
CAS:<p>Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).</p>Fórmula:C24H26N2O2Pureza:98.88% - 99.68%Cor e Forma:SolidPeso molecular:374.48Terbutaline
CAS:Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterolFórmula:C12H19NO3Pureza:99.12%Cor e Forma:SolidPeso molecular:225.3Dynarrestin
CAS:Dynarrestin inhibits cytoplasmic dynein 1/2, preventing microtubule sliding without affecting ATP hydrolysis or ciliogenesis.Fórmula:C22H23F2N3O2SPureza:99.64%Cor e Forma:SolidPeso molecular:431.5Orphenadrine hydrochloride
CAS:Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.Fórmula:C18H23NO·HClPureza:99.88%Cor e Forma:Liquid About 5 5 Bitter Numbing Taste (Ntp 1992)Peso molecular:305.85Cinnarizine
CAS:<p>Cinnarizine is a piperazine, blocks H1-receptor & Ca-channels, has vasodilating & antiemetic effects, may cause Parkinson-like symptoms.</p>Fórmula:C26H28N2Pureza:99.94%Cor e Forma:SolidPeso molecular:368.51Perphenazine
CAS:<p>Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.</p>Fórmula:C21H26ClN3OSPureza:99.3% - 99.99%Cor e Forma:SolidPeso molecular:403.97Naftifine hydrochloride
CAS:<p>Naftifine HCl: synthetic antifungal; inhibits squalene epoxidase, disrupting fungal cell sterol synthesis.</p>Fórmula:C21H22ClNPureza:98.75% - 99.84%Cor e Forma:SolidPeso molecular:323.86Pericyazine
CAS:<p>Pericyazine (Propericiazine) is a selective D2-dopamine receptor antagonist.</p>Fórmula:C21H23N3OSPureza:99.61%Cor e Forma:SolidPeso molecular:365.49DREADD agonist 21
CAS:<p>DREADD agonist 21 is a potent agonist of human muscarinic acetylcholine M3 receptors (EC50=1.7 nM).</p>Fórmula:C17H18N4Pureza:99.94%Cor e Forma:SolidPeso molecular:278.35Leronlimab
CAS:<p>Leronlimab (PRO 140), a humanized IgG4 monoclonal antibody, targets CCR5 to combat HIV and cancer.</p>Pureza:SDS-PAGE:95.0%;SEC-HPLC:99.6%Cor e Forma:LiquidPeso molecular:146.66 kDaSEP-363856 hydrochloride
CAS:<p>SEP-363856 hydrochloride is an oral, CNS-active psychotropic for schizophrenia with a non-D2/5-HT2A mechanism.</p>Fórmula:C9H14ClNOSPureza:99.86% - 99.99%Cor e Forma:SolidPeso molecular:219.73Dexchlorpheniramine Maleate
CAS:<p>Dexchlorpheniramine Maleate, an antihistamine with anticholinergic effects, treats allergies like hay fever. It's the active isomer of chlorpheniramine.</p>Fórmula:C20H23ClN2O4Pureza:99.58%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:390.86JP1302 dihydrochloride
CAS:<p>JP1302 dihydrochloride: selective α2C-adrenoceptor antagonist; Ki=28 nM, Kb=16 nM.</p>Fórmula:C24H26Cl2N4Pureza:99.61%Cor e Forma:SolidPeso molecular:441.4PF-04995274
CAS:<p>PF-04995274: potent, selective partial 5-HT4R agonist; EC50 0.26-0.47 nM; brain penetrant; may treat Alzheimer's cognitive issues.</p>Fórmula:C23H32N2O6Pureza:99.52%Cor e Forma:SolidPeso molecular:432.51Tiapride hydrochloride
CAS:<p>Tiapride is a selective blocker of D2/3 dopamine receptors in the brain.</p>Fórmula:C15H24N2O4S·HClPureza:99.4% - 99.77%Cor e Forma:SolidPeso molecular:364.89N6-Benzyl-5'-ethylcarboxamido adenosine
CAS:<p>N6-Benzyl-5'-ethylcarboxamido adenosine is a selective A3 adenosine receptor agonist.</p>Fórmula:C19H22N6O4Cor e Forma:SolidPeso molecular:398.42MK-0493 HCl
CAS:<p>MK-0493 is a novel, potent, and selective agonist for melanocortin receptor 4 (MC4R).</p>Fórmula:C30H39Cl2F2N3O2Cor e Forma:SolidPeso molecular:582.55Neurokinin A(4-10)
CAS:<p>Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .</p>Fórmula:C34H54N8O10SPureza:98%Cor e Forma:SolidPeso molecular:766.91Calcitonin-13C6,15N4 TFA
<p>Calcitonin-13CIC6,15NIC4(salmon) (Salmon calcitonin-13CIC6,15NIC4) TFA is a version of calcitonin(salmon) labeled with carbon-13 and nitrogen-15. This hormone regulates calcium and acts dualistically as an agonist to both amylin and calcitonin receptors, promoting bone formation while inhibiting bone resorption.</p>Fórmula:C1401C5H240N4315NO48S2·5C2HF3O2Cor e Forma:SolidPeso molecular:4007.93Urocortin II, human
Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor.Fórmula:C194H339N63O54SPureza:98%Cor e Forma:SolidPeso molecular:4450.28MD01-67
CAS:<p>MD01-67 is a macrocyclic compound selectively targeting the neurotensin 2 receptor (NTS2), with a Ki of 2.9 nM. It exhibits analgesic activity and reduces tactile hypersensitivity in rat models of acute, sustained, and chronic inflammatory pain.</p>Fórmula:C37H58N8O8Cor e Forma:SolidPeso molecular:742.91CB2R/FAAH modulator-3
CAS:<p>CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH.</p>Fórmula:C22H31NO2Pureza:99.81%Cor e Forma:SoildPeso molecular:341.49A2A/A3 AR antagonist-1
<p>A2A/A3 AR antagonist-1 is a dual fluorescent AR ligand with K i of 90 nM (hA2A) & 31.8 nM (hA3).</p>Fórmula:C56H71N15O12S2Cor e Forma:SolidPeso molecular:1210.3913,14-dihydro Prostaglandin F2α
CAS:<p>13,14-dihydro Prostaglandin F2α (13,14-dihydro PGF2α) is the analog of PGF2α which has no unsaturation in the lower side chain.</p>Fórmula:C20H36O5Cor e Forma:SolidPeso molecular:356.503L-796,778 acetate
<p>L-796,778 acetate is a slective somatostatin receptor agonist with IC50 of 24nM for sst3, for sst1, sst2, sst4 and sst5, IC50 is >1000nM.</p>Fórmula:C31H44N6O9Pureza:98%Cor e Forma:SoildPeso molecular:644.72Seglitide acetate
CAS:<p>Seglitide acetate (MK-678) is a selective agonist of sst2 somatostatin receptor.</p>Fórmula:C46H60N8O9Pureza:98.87%Cor e Forma:SolidPeso molecular:869.02GV-150013X
CAS:<p>GV-150013X ((S)-1-(1-(adamantan-1-ylmethyl)-2,4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-3-phenylurea) is a potent CCKB antiagonist, pKi</p>Fórmula:C33H34N4O3Pureza:99.94%Cor e Forma:SoildPeso molecular:534.65IRL-1038 TFA
<p>IRL-1038 TFA is an ETB receptor antagonist used in the study of cardiovascular disease.</p>Fórmula:C70H93F3N14O17S2Pureza:98.79%Cor e Forma:SolidPeso molecular:1523.7
