CAS 105102-22-5: Mometasone
Description:Mometasone is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, primarily used in the treatment of various allergic and inflammatory conditions. It is characterized by its potent glucocorticoid activity, which helps reduce inflammation and alleviate symptoms associated with conditions such as asthma, allergic rhinitis, and skin disorders. Mometasone is typically administered topically, intranasally, or via inhalation, depending on the condition being treated. The chemical structure of mometasone includes a steroid backbone, which is essential for its biological activity, and it features specific functional groups that enhance its potency and selectivity for glucocorticoid receptors. Its pharmacokinetics indicate a favorable absorption profile, with minimal systemic exposure when used as directed, thereby reducing the risk of systemic side effects commonly associated with corticosteroids. Mometasone is generally well-tolerated, but like all medications, it may have potential side effects, including local irritation or allergic reactions. Overall, mometasone is an effective therapeutic agent in managing inflammatory and allergic conditions.
Formula:C22H28Cl2O4
InChI:InChI=1S/C22H28Cl2O4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-17,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChI key:InChIKey=QLIIKPVHVRXHRI-CXSFZGCWSA-N
SMILES:O=C1C=CC2(C(=C1)CCC3C4CC(C)C(O)(C(=O)CCl)C4(C)CC(O)C32Cl)C
- Synonyms:
- (11Beta,16Alpha)-9,21-Dichloro-11,17-Dihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
- (11Beta,16Alpha)-9,21-Dichloro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Furan-2-Carboxylate
- (11β,16α)-9,21-Dichloro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
- (8xi,11beta,16alpha)-9,21-Dichlor-11,17-dihydroxy-16-methylpregna-1,4-dien-3,20-dion
- (8xi,11beta,16alpha)-9,21-Dichloro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
- (9R,10S,11S,13S,14S,16R,17R)-9-Chloro-17-(chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
- Pregna-1,4-Diene-3,20-Dione, 9,21-Dichloro-11,17-Dihydroxy-16-Methyl-, (8Xi,11Beta,16Alpha)-
- Pregna-1,4-diene-3,20-dione, 9,21-dichloro-11,17-dihydroxy-16-methyl-, (11β,16α)-
- (+)-Mometasone
- Mometasone
- See more synonyms
