CAS 1177-87-3: Dexamethasone acetate

Description: Dexamethasone acetate is a synthetic corticosteroid with anti-inflammatory and immunosuppressant properties. It is a derivative of dexamethasone, characterized by the addition of an acetate group, which enhances its solubility and bioavailability. This compound is typically administered via injection or as an oral formulation and is used to treat a variety of conditions, including allergies, autoimmune disorders, and certain types of cancer. Dexamethasone acetate works by inhibiting the release of inflammatory mediators and modulating the immune response. It has a relatively long half-life compared to other corticosteroids, allowing for less frequent dosing. The substance is known for its potency and effectiveness, but it can also lead to side effects such as increased blood sugar levels, weight gain, and potential suppression of the adrenal gland with prolonged use. As with all corticosteroids, careful monitoring is essential to mitigate adverse effects and ensure therapeutic efficacy.

Formula: C₂₄H₃₁FO₆

InChI: InChI=1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1

InChI key: InChIKey=AKUJBENLRBOFTD-RPRRAYFGSA-N

SMILES: O=C1C=CC2(C(=C1)CCC3C4CC(C)C(O)(C(=O)COC(=O)C)C4(C)CC(O)C32F)C

Synonyms:

• (11Beta,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• (11Beta,16Alpha)-9-Fluoro-11,21-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-17-Yl Acetate
• (11β,16α)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
• (16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• (8Xi,11Beta,14Xi,16Alpha)-9-Fluoro-11,17-Dihydroxy-16-Methyl-3,20-Dioxopregna-1,4-Dien-21-Yl Acetate
• 16α-Methyl-9α-fluoroprednisolone 21-acetate
• Dalalone DP
• Dalalone LA
• Decadron LA
• Decadronal
• Dectancyl
• Dex-Cortidelt acetate
• Dexa-Cortisyl
• Dexamethasone Acetate
• Dexamethasone-17-acetate
• Dexamethasoneacetate
• Fortecortin
• Fortecortin (crystal suspension)
• NSC 39471
• Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 21-acetate

Dexamethasone acetate

CAS: 1177-87-3

Dexamethasone has many uses in the treatment of cancer. Dexamethasone relieves inflammation in various parts …

• Formula: C₂₄H₃₁FO₆
• Molecular weight: 434.5

Dexamethasone acetate RS

CAS: 1177-87-3

• Formula: C₂₄H₃₁FO₆
• Molecular weight: 434.4977

Dexamethasone acetate CRS

CAS: 1177-87-3

Dexamethasone acetate for peak identification CRS

CAS: 1177-87-3

• Formula: C₂₄H₃₁FO₆
• Color and Shape: Crystalline Powder. Whitish. Powder.
• Molecular weight: 434.4977

Dexamethasone Acetate

CAS: 1177-87-3

Halogenated derivatives of adrenal cortical hormones

• Formula: C₂₄H₃₁FO₆
• Color and Shape: White Powder
• Molecular weight: 434.21047

Dexamethasone acetate

CAS: 1177-87-3

Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.

• Formula: C₂₄H₃₁FO₆
• Purity: 99.22% - 99.65%
• Color and Shape: White Or Almost White Crystalline Powder
• Molecular weight: 434.5

Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16α)-

CAS: 1177-87-3

• Formula: C₂₄H₃₁FO₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 434.4977431999998

Dexamethasone 21-acetate

CAS: 1177-87-3

• Formula: C₂₄H₃₁FO₆
• Purity: (HPLC) ≥ 98.0%
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 434.50

Dexamethasone acetate

CAS: 1177-87-3

• Purity: 99%
• Molecular weight: 434.5g/mol

Dexamethasone 21-acetate, USP grade

CAS: 1177-87-3

• Formula: C₂₄H₃₁FO₆
• Purity: (HPLC) 97.0 - 102.0 %
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 434.50

Dexamethasone Acetate

CAS: 1177-87-3

• Purity: 98%
• Molecular weight: 434.5g/mol

Dexamethasone Acetate (Dexamethasone EP Impurity G, Betamethasone Acetate EP Impurity B)

CAS: 1177-87-3

• Formula: C₂₄H₃₁FO₆
• Color and Shape: White To Off-White Solid
• Molecular weight: 434.50

Dexamethasone 21-Acetate

CAS: 1177-87-3

• Formula: C₂₄H₃₁FO₆
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 434.50

Dexamethasone acetate

CAS: 1177-87-3

• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 434.210466932

Dexamethasone 21-acetate

CAS: 1177-87-3

• Formula: C₂₄H₃₁FO₆
• Color and Shape: White
• Molecular weight: 434.50

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

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• Color and Shape: Mixture

Dexamethasone Acetate

CAS: 1177-87-3

• Formula: C₂₄H₃₁FO₆
• Color and Shape: Neat
• Molecular weight: 434.50

Dexamethasone Acetate-13C3 (Dexamethasone EP Impurity G-13C3, Betamethasone Acetate EP Impurity B-13C3)

CAS: 1177-87-3

• Formula: C₂₁₁₃C₃H₃₁FO₆
• Molecular weight: 437.48

21-O-Acetyl Dexamethasone

CAS: 1177-87-3

Impurity Betamethasone Acetate EP Impurity B Applications 21-O-Acetyl Dexamethasone (Betamethasone Acetate EP Impurity B) is …

• Formula: C₂₄H₃₁FO₆
• Color and Shape: White
• Molecular weight: 434.50

21-O-Acetyl Dexamethasone-d5

CAS: 1177-87-3

Applications Isotope labelled intermediate in the synthesis of Dexamethasone (D298800), a glucocorticoid anti-inflammatory agent. References …

• Formula: C₂₄D₅H₂₆FO₆
• Color and Shape: Neat
• Molecular weight: 439.53