CAS 13609-67-1
:Hydrocortisone butyrate
Description:
Hydrocortisone butyrate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, primarily used in dermatological formulations for the treatment of various skin conditions, such as eczema and psoriasis. It is characterized by its ability to reduce inflammation and alleviate symptoms like itching and redness. The substance is a white to off-white crystalline powder, which is typically soluble in organic solvents but has limited solubility in water. Hydrocortisone butyrate acts by binding to glucocorticoid receptors, modulating gene expression, and inhibiting the release of pro-inflammatory mediators. Its potency is enhanced by the butyrate ester, which improves skin penetration and bioavailability. The compound is often formulated in creams, ointments, or lotions for topical application, allowing for localized treatment with minimal systemic absorption. As with other corticosteroids, prolonged use may lead to side effects, including skin thinning and potential systemic effects, necessitating careful management and adherence to prescribed dosages.
Formula:C25H36O6
InChI:InChI=1S/C25H36O6/c1-4-5-21(30)31-25(20(29)14-26)11-9-18-17-7-6-15-12-16(27)8-10-23(15,2)22(17)19(28)13-24(18,25)3/h12,17-19,22,26,28H,4-11,13-14H2,1-3H3/t17-,18-,19-,22+,23-,24-,25-/m0/s1
InChI key:InChIKey=BMCQMVFGOVHVNG-TUFAYURCSA-N
SMILES:O(C(CCC)=O)[C@@]1(C(CO)=O)[C@]2(C)[C@@](CC1)([C@]3([C@]([C@@H](O)C2)([C@]4(C)C(CC3)=CC(=O)CC4)[H])[H])[H]
Synonyms:- (11Beta)-11,21-Dihydroxy-3,20-Dioxopregn-4-En-17-Yl Butanoate
- (11β)-11,21-Dihydroxy-17-(1-oxobutoxy)pregn-4-ene-3,20-dione
- (9Xi,11Beta,14Xi)-11,21-Dihydroxy-3,20-Dioxopregn-4-En-17-Yl Butanoate
- 4-Pregnene-11β,21-dihydroxy-17α-butyryloxy-3,20-dione
- Alfason
- Butyric acid, 17-ester with cortisol
- Cortisol, 17-butyrate
- Hydrocortisone 17α-butyrate
- Hydrocortisone Butyrate
- Laticort
- Locoid
- Plancol
- Pregn-4-ene-3,20-dione, 11,21-dihydroxy-17-(1-oxobutoxy)-, (11β)-
- See more synonyms
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Found 16 products.
Hydrocortisone 17-Butyrate
CAS:Formula:C25H36O6Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:432.56Hydrocortisone Butyrate
CAS:Adrenal cortical hormones and their derivatives nesoiFormula:C25H36O6Color and Shape:White PowderMolecular weight:432.25119(1R,3aS,3bS,9aR,9bS,10S,11aS)-10-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl butanoate
CAS:Formula:C25H36O6Purity:98%Color and Shape:SolidMolecular weight:432.5497Hydrocortisone 17-butyrate
CAS:<p>Hydrocortisone 17-butyrate (Cortisol 17-butyrate) is a glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects.</p>Formula:C25H36O6Purity:98% - 99.57%Color and Shape:SolidMolecular weight:432.55Hydrocortisone butyrate, USP grade
CAS:Formula:C25H36O6Purity:≤ 1.0%Color and Shape:White to almost white powder or crystalsMolecular weight:432.55GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
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Color and Shape:MixtureHydrocortisone 17-Butyrate
CAS:Controlled ProductFormula:C25H36O6Color and Shape:NeatMolecular weight:432.55Hydrocortisone 17-Butyrate
CAS:Controlled ProductFormula:C25H36O6Color and Shape:NeatMolecular weight:432.55Hydrocortisone butyrate
CAS:Formula:C25H36O6Purity:≥ 98.0% (anhydrous basis)Color and Shape:White to almost white powderMolecular weight:432.55Hydrocortisone Butyrate
CAS:Controlled Product<p>Applications Hydrocortisone Butyrate is a topical corticosteroid use to treat a variety of dermatological conditions. It acts as an antiinflammatory, antiproliferative and immunosuppresive agent.<br>References Foti, C. et al.: J. Biol. Reg. Homeo. Agents, 25, 683 (2011); Zirwas, M. et al.: J. Drugs Dermatol., 11, s9 (2012);<br></p>Formula:C25H36O6Color and Shape:White Off-WhiteMolecular weight:432.55Hydrocortisone-17-butyrate
CAS:Controlled Product<p>Hydrocortisone-17-butyrate is a drug used for the treatment of inflammatory bowel disease and other infectious diseases. It is used in combination with other drugs to treat skin lesions, such as those that may be caused by an infection. Hydrocortisone-17-butyrate has been shown to be effective in treating cutaneous lesions in patients who are immunocompetent. The drug has also been shown to have significant cytotoxicity against human colon cancer cells. Hydrocortisone-17-butyrate is metabolized by hydroxylation, which can lead to unwanted side effects.</p>Formula:C25H36O6Purity:Min. 95%Color and Shape:PowderMolecular weight:432.55 g/mol
