CAS 378-44-9: Betamethasone

Description: Betamethasone is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, commonly used in the treatment of various conditions such as allergies, skin disorders, and autoimmune diseases. It is characterized by its potent glucocorticoid activity, which helps reduce inflammation and modulate the immune response. Betamethasone has a molecular formula that reflects its steroid structure, typically featuring a cyclopentanoperhydrophenanthrene core, with specific functional groups that enhance its biological activity. The substance is often administered in various forms, including topical creams, injections, and oral tablets, depending on the condition being treated. Its pharmacokinetics involve rapid absorption and metabolism, with a relatively long half-life compared to other corticosteroids, allowing for less frequent dosing. However, prolonged use can lead to side effects such as adrenal suppression, weight gain, and increased susceptibility to infections. As with any medication, it is essential to use betamethasone under medical supervision to manage potential risks and benefits effectively.

Formula: C₂₂H₂₉FO₅

InChI: InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

InChI key: InChIKey=UREBDLICKHMUKA-DVTGEIKXSA-N

SMILES: O=C1C=CC2(C(=C1)CCC3C4CC(C)C(O)(C(=O)CO)C4(C)CC(O)C32F)C

Synonyms:

• (11Beta,16Alpha)-9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
• (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
• 9-Fluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
• 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione
• 9-Fluoro-16β-methylprednisolone
• 9A-Fluoro-11B,17A,21-Trihydroxy-16B-Methylpregna-1,4-Diene-3,20-Dione
• 9Alpha-Fluoro-16Beta-Methylprednisolone
• 9α-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione
• 9α-Fluoro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione
• 9α-Fluoro-16β-methylprednisolone
• Becort
• Bedifos
• Betacorlan
• Betacortil
• Betacortril
• Betadexamethasone
• Betametasona
• Betametasone
• Betamethason
• Betamethasone base
• Betamethazone
• Betapredol
• Betasolon
• Bethamethasone
• Betnelan
• Betsolan
• Bifas
• Celestan
• Celestene
• Celeston
• Celestone
• Cidoten
• Colircusi betamida
• Dermabet
• Desacort-Beta
• Diprospan
• Ethamethasoneb
• Flosteron
• Flubenisolone
• Nsc 39470
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11β,16β)-
• Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-
• Rinderon
• Rinderon A
• Sch 4831
• Visubeta
• β-Methasone
• β-Methasone alcohol
• Betamethasone

Betamethasone RS

CAS: 378-44-9

• Formula: C₂₂H₂₉FO₅
• Molecular weight: 392.4611

Betamethasone CRS

CAS: 378-44-9

• Formula: C₂₂H₂₉FO₅
• Color and Shape: Crystalline Powder. White. Whitish. Powder.
• Molecular weight: 392.4611

Betamethasone

CAS: 378-44-9

• Formula: C₂₂H₂₉FO₅
• Purity: 98.8%
• Color and Shape: Off White
• Molecular weight: 392.1999

Betamethasone

CAS: 378-44-9

Halogenated derivatives of adrenal cortical hormones

• Formula: C₂₂H₂₉FO₅
• Color and Shape: White Off-White Crystalline Powder
• Molecular weight: 392.46 g/mol

9a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione

CAS: 378-44-9

• Formula: C₂₂H₂₉FO₅
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 392.4611

Betamethasone

CAS: 378-44-9

• Formula: C₂₂H₂₉FO₅
• Purity: ≥ 97.0%
• Color and Shape: White to off-white powder
• Molecular weight: 392.46

Betamethasone-d5 (Betamethasone Acetate EP Impurity A-d5, Betamethasone Dipropionate EP Impurity A-d5, Betamethasone Valerate EP Impurity A-d5, Dexamethasone EP Impurity B-d5)

CAS: 378-44-9

• Formula: C₂₂H₂₄D₅FO₅
• Color and Shape: White To Off-White Solid
• Molecular weight: 397.50

Betamethasone (Betamethasone Acetate EP Impurity A, Betamethasone Dipropionate EP Impurity A, Betamethasone Valerate EP Impurity A, Dexamethasone EP Impurity B)

CAS: 378-44-9

• Formula: C₂₂H₂₉FO₅
• Molecular weight: 392.47

βmethasone, 97%

CAS: 378-44-9

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂₂H₂₉FO₅
• Purity: 97%
• Color and Shape: Powder, White to off-white
• Molecular weight: 392.47

Betamethasone

CAS: 378-44-9

• Formula: C₂₂H₂₉FO₅
• Color and Shape: Neat
• Molecular weight: 392.46

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

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• Color and Shape: Mixture

Betamethasone

CAS: 378-44-9

• Formula: C₂₂H₂₉FO₅
• Color and Shape: Neat
• Molecular weight: 392.46

Betamethasone

CAS: 378-44-9

• Formula: C₂₂H₂₉FO₅
• Purity: >98.0%(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 392.47

Betamethasone 100 µg/mL in Acetonitrile

CAS: 378-44-9

• Formula: C₂₂H₂₉FO₅
• Color and Shape: Single Solution
• Molecular weight: 392.46

Betamethasone RS

CAS: 378-44-9

• Color and Shape: White Off-White Solid Crystalline Powder

Betamethasone-d5

CAS: 378-44-9

Stability Hygroscopic Applications Glucocorticoid. References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 …

• Formula: C₂₂H₂₄D₅FO₅
• Color and Shape: Off-White To Light Yellow
• Molecular weight: 397.49

Betamethasone

CAS: 378-44-9

• Purity: 95%
• Molecular weight: 392.467010498047

Betamethasone

CAS: 378-44-9

• Formula: C₂₂H₂₉FO₅
• Color and Shape: Neat
• Molecular weight: 392.46

Betamethasone

CAS: 378-44-9

Please enquire for more information about Betamethasone including the price, delivery time and more detailed …

• Formula: C₂₂H₂₉FO₅
• Purity: Min. 97 Area-%
• Color and Shape: White Powder
• Molecular weight: 392.46 g/mol

Betamethasone - Bio-X ™

CAS: 378-44-9

Betamethasone is a potent anti-inflammatory agent that belongs to the group of corticosteroids. It is …

• Formula: C₂₂H₂₉FO₅
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 392.46 g/mol