CymitQuimica logo

CAS 514-36-3

:

Fludrocortisone acetate

Description:
Fludrocortisone acetate is a synthetic corticosteroid with anti-inflammatory and mineralocorticoid properties, primarily used in the treatment of conditions such as adrenal insufficiency and orthostatic hypotension. It is characterized by its ability to enhance sodium retention and potassium excretion in the kidneys, which helps to regulate blood pressure and fluid balance. The compound is typically administered orally and is known for its relatively high potency compared to other corticosteroids. Fludrocortisone acetate has a molecular formula that reflects its steroidal structure, featuring a cyclopentanoperhydrophenanthrene core, which is common among corticosteroids. Its pharmacological effects are mediated through the activation of mineralocorticoid receptors, leading to various physiological responses. The substance is generally well-tolerated, but potential side effects may include hypertension, hypokalemia, and fluid retention, necessitating careful monitoring during treatment. As with all corticosteroids, it is important to use fludrocortisone acetate under medical supervision to manage dosage and mitigate adverse effects effectively.
Formula:C23H31FO6
InChI:InChI=1S/C23H31FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h10,16-18,27,29H,4-9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1
InChI key:InChIKey=SYWHXTATXSMDSB-GSLJADNHSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(COC(C)=O)=O)(O)CC3)[H])(CCC=4[C@]2(C)CCC(=O)C4)[H]
Synonyms:
  • (11Beta)-9-Fluoro-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl Acetate
  • (11β)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxypregn-4-ene-3,20-dione
  • (8Xi,10Xi,13Xi,14Xi,17Xi)-9-Fluoro-11,17-Dihydroxy-3,20-Dioxopregn-4-En-21-Yl Acetate
  • 9-Fluoro-11-beta,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate
  • 9-Fluoro-11beta,17,21-trihydroxypregn-4-ene-3,20-dione 21-acetate
  • 9-Fluorohydrocortisone acetate
  • 9-alpha-Fluorohydrocortisone acetate
  • 9-alpha-Fluorohydrocortisone-21-acetate
  • 9alpha-Fluorohydrocortisone 21-acetate
  • 9alpha-Fluorohydrocortisone acetate
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 18 products.