CAS 66734-13-2: Alclometasone dipropionate

Description: Alclometasone dipropionate is a synthetic corticosteroid primarily used for its anti-inflammatory and anti-allergic properties in dermatological applications. It is characterized by its potent glucocorticoid activity, which helps in reducing inflammation and suppressing immune responses. The substance is typically formulated as a topical cream or ointment, making it effective for treating various skin conditions such as eczema, dermatitis, and psoriasis. Alclometasone dipropionate exhibits a favorable pharmacokinetic profile, allowing for localized action with minimal systemic absorption when applied to the skin. Its chemical structure includes a dipropionate ester, which enhances its lipophilicity and skin penetration. The compound is generally well-tolerated, although potential side effects may include skin irritation or atrophy with prolonged use. As with other corticosteroids, it is important to use Alclometasone dipropionate as directed to minimize the risk of adverse effects and to ensure effective treatment outcomes.

Formula: C₂₈H₃₇ClO₇

InChI: InChI=1S/C28H37ClO7/c1-6-22(33)35-14-21(32)28(36-23(34)7-2)15(3)10-18-24-19(29)12-16-11-17(30)8-9-26(16,4)25(24)20(31)13-27(18,28)5/h8-9,11,15,18-20,24-25,31H,6-7,10,12-14H2,1-5H3/t15-,18+,19-,20+,24-,25+,26+,27+,28+/m1/s1

InChI key: InChIKey=DJHCCTTVDRAMEH-DUUJBDRPSA-N

SMILES: O=C1C=CC2(C(=C1)CC(Cl)C3C4CC(C)C(OC(=O)CC)(C(=O)COC(=O)CC)C4(C)CC(O)C32)C

Synonyms:

• (7Alpha,11Beta,16Alpha)-7-Chloro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Dipropanoate
• (7Alpha,8Xi,9Xi,10Xi,13Xi,16Alpha)-7-Chloro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Dipropanoate
• (7α,11β,16α)-7-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione
• 17,21-Di(Propionate) De 7Α-Chloro-11Β,17,21-Trihydroxy-16Α-Methylpregna-1,4-Diene-3,20-Dione
• 17,21-Di(Propionato) De 7Α-Cloro-11Β,17,21-Trihidroxi-16Α-Metilpregna-1,4-Dieno-3,20-Diona
• 7Α-Chloro-11Β,17,21-Trihydroxy-16Α-Methylpregna-1,4-Diene-3,20-Dione 17,21-Di(Propionate)
• 7α-Chlor-11β,17,21-trihydroxy-16α-methylpregna-1,4-dien-3,20-dion-17,21-di(propionat)
• Aclovate
• Alclometasone Dipropionate
• Alclometasone-17,21-Dipropionate
• Almeta
• Delonal
• Pregna-1,4-diene-3,20-dione, 7-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (7α,11β,16α)-
• Sch 22219
• Vaderm

Alclometasone Dipropionate

CAS: 66734-13-2

Halogenated derivatives of adrenal cortical hormones

• Formula: C₂₈H₃₇ClO₇
• Color and Shape: Powder
• Molecular weight: 520.22278

Alclometasone Dipropionate

CAS: 66734-13-2

• Formula: C₂₈H₃₇ClO₇
• Color and Shape: White To Off-White Solid
• Molecular weight: 521.05

Alclometasone dipropionate

CAS: 66734-13-2

Alclometasone dipropionate (Sch 22219) is a glucocorticoid with antiproliferative and vasoconstrictive properties that is used …

• Formula: C₂₈H₃₇ClO₇
• Purity: 99.57% - 99.62%
• Color and Shape: Solid
• Molecular weight: 521.04

Alclometasone dipropionate

CAS: 66734-13-2

• Purity: 99%
• Molecular weight: 521.04g/mol

GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol

CAS: 105102-22-5 1177-87-3 124-94-7 13609-67-1 14484-47-0 1524-88-5 2135-17-3 2152-44-5 25122-46-7 25122-57-0 3093-35-4 33564-31-7 356-12-7 378-44-9 3801-06-7 3870-07-3 426-13-1 4419-39-0 50-02-2 50-03-3 50-04-4 50-23-7 50-24-8 51022-69-6 51333-22-3 514-36-3 53-06-5 53-36-1 5534-09-8 5593-20-4 57524-89-7 66734-13-267-78-7 73771-04-7 76-25-5 80474-14-2 83-43-2 987-24-6

• Color and Shape: Mixture

Alclometasone dipropionate

CAS: 66734-13-2

• Formula: C₂₈H₃₇ClO₇
• Purity: 97.0 - 102.0 %
• Color and Shape: White to off-white crystalline powder
• Molecular weight: 521.04

Alclometasone 17,21-Dipropionate

CAS: 66734-13-2

Applications Alclometasone-17,21-dipropionate is an synthetic glucocorticoid steroid used for inflammatory skin conditions. Alclometasone-17,21-dipropionate is topically …

• Formula: C₂₈H₃₇ClO₇
• Color and Shape: Neat
• Molecular weight: 521.04

Alclometasone dipropionate

CAS: 66734-13-2

Please enquire for more information about Alclometasone dipropionate including the price, delivery time and more …

• Formula: C₂₈H₃₇CI₀₇
• Purity: Min. 95%
• Molecular weight: 1,273.94 g/mol