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CAS 80474-14-2

:

Fluticasone propionate

Description:
Fluticasone propionate is a synthetic corticosteroid with anti-inflammatory properties, primarily used in the treatment of respiratory conditions such as asthma and allergic rhinitis. It is characterized by its high potency and selective action on glucocorticoid receptors, which helps to reduce inflammation and immune response in the airways. The substance is typically administered via inhalation, nasal spray, or topical formulations, allowing for localized effects with minimal systemic absorption. Fluticasone propionate is known for its favorable pharmacokinetic profile, including a relatively long half-life and extensive first-pass metabolism, which contributes to its efficacy and safety. The compound is generally well-tolerated, although potential side effects may include local irritation, headache, or, with long-term use, systemic effects such as adrenal suppression. Its chemical structure includes a fluorinated steroid backbone, which enhances its potency and stability. Overall, fluticasone propionate is a critical medication in managing chronic inflammatory conditions, providing significant relief for patients when used appropriately.
Formula:C25H31F3O5S
InChI:InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
InChI key:InChIKey=WMWTYOKRWGGJOA-CENSZEJFSA-N
SMILES:O(C(CC)=O)[C@@]1(C(SCF)=O)[C@]2(C)[C@@](C[C@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)[H])[H]
Synonyms:
  • Atemur Mite
  • Axotide
  • Cci 18781
  • Cutivate
  • Cutivate cream
  • Cyclesonide
  • F 9428
  • Flixonase
  • Flixonase Nasal Spray
  • Flixotide
  • See more synonyms
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