Angiogenesis
Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.
Subcategories of "Angiogenesis"
- BTK(166 products)
- Bcr-Abl(117 products)
- EGFR(578 products)
- FAK(72 products)
- FLT(86 products)
- Fibroblast Growth Factor Receptor (FGFR)(179 products)
- JAK(244 products)
- PDGFR(129 products)
- RAAS(89 products)
- Src(82 products)
- Syk(37 products)
- Thrombin(56 products)
- VDA(2 products)
- VEGFR(242 products)
Show 6 more subcategories
Found 2369 products of "Angiogenesis"
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PF-6274484
CAS:PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M and WT-EGFR, respectively.Formula:C18H14ClFN4O2Purity:97.71%Color and Shape:SolidMolecular weight:372.78Ref: TM-T22396
2mg38.00€5mg57.00€10mg96.00€25mg177.00€50mg333.00€100mg495.00€500mg1,071.00€1mL*10mM (DMSO)63.00€Ibrutinib
CAS:Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.Formula:C25H24N6O2Purity:98% - 99.95%Color and Shape:SolidMolecular weight:440.5Agerafenib
CAS:Agerafenib (CEP32496) is a highly potent inhibitor of BRAF.Formula:C24H22F3N5O5Purity:95.78% - 99.23%Color and Shape:SolidMolecular weight:517.46Ref: TM-T2070
1mg39.00€5mg93.00€10mg124.00€25mg219.00€50mg358.00€100mg530.00€200mg757.00€1mL*10mM (DMSO)90.00€Nocodazole
CAS:Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.Formula:C14H11N3O3SPurity:98% - 99.91%Color and Shape:Physical Description White Powder (Ntp 1992)Molecular weight:301.32Ref: TM-T2802
5mg34.00€10mg52.00€25mg94.00€50mg165.00€100mg268.00€200mg399.00€500mg647.00€1mL*10mM (DMSO)38.00€Derazantinib dihydrochloride
CAS:Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.Formula:C29H31Cl2FN4OColor and Shape:SolidMolecular weight:541.49EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formula:C25H30N6OPurity:98.99% - >99.99%Color and Shape:SolidMolecular weight:430.55Ref: TM-T2427
5mg46.00€10mg70.00€25mg120.00€50mg202.00€100mg316.00€200mg467.00€500mg747.00€1mL*10mM (DMSO)49.00€4-(6,7-dimethoxyquinolin-4-yl)oxyaniline
CAS:4-(6,7-dimethoxyquinolin-4-yl)oxyaniline is a quinoline used in creating drugs and pesticides.Formula:C17H16N2O3Purity:99.93%Color and Shape:SolidMolecular weight:296.32Ritlecitinib
CAS:Ritlecitinib (PF-06651600) is an orally available, selective JAK3 inhibitor and does not affect the activity of JAK1/2.Cost-effective and quality-assured.Formula:C15H19N5OPurity:98.82% - 99.92%Color and Shape:SolidMolecular weight:285.34Ref: TM-T5382
2mg37.00€5mg52.00€10mg90.00€25mg205.00€50mg290.00€100mg408.00€200mg595.00€1mL*10mM (DMSO)73.00€AZD8931 diFuMaric acid
CAS:AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).Formula:C31H33ClFN5O11Purity:99.92%Color and Shape:SolidMolecular weight:706.1Ref: TM-T8751
1mg62.00€5mg125.00€10mg180.00€25mg298.00€50mg419.00€100mg567.00€200mg752.00€1mL*10mM (DMSO)178.00€CYC-116
CAS:CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not activeFormula:C18H20N6OSPurity:97.36% - 97.59%Color and Shape:SolidMolecular weight:368.46Tofacitinib
CAS:Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.Formula:C16H20N6OPurity:99% - >99.99%Color and Shape:SolidMolecular weight:312.37AEE788
CAS:AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.Formula:C27H32N6Purity:98% - >99.99%Color and Shape:SolidMolecular weight:440.58Ref: TM-T2116
2mg47.00€5mg70.00€10mg103.00€25mg188.00€50mg325.00€100mg490.00€500mg1,103.00€1mL*10mM (DMSO)77.00€MELK-8a
CAS:MELK-8a inhibits MELK kinase crucial for cancer cell mitosis (IC50: 2 nM).Formula:C25H32N6OColor and Shape:SolidMolecular weight:432.56WZ4002
CAS:WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.Formula:C25H27ClN6O3Purity:97.51%Color and Shape:SolidMolecular weight:494.97Ref: TM-T6238
2mg34.00€5mg49.00€10mg70.00€25mg111.00€50mg177.00€100mg313.00€200mg464.00€1mL*10mM (DMSO)50.00€Brigatinib
CAS:Brigatinib (AP-26113) is a highly potent and selective ALK inhibitor.
Formula:C29H39ClN7O2PPurity:97.18% - >99.99%Color and Shape:SolidMolecular weight:584.09Trastuzumab
CAS:Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.Purity:97.1% (SDS-PAGE); 99.2% (SEC-HPLC) - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%Color and Shape:LiquidMolecular weight:145.36 kDaOlafertinib
CAS:Olafertinib (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.Formula:C29H28F2N6O2Purity:98.62% - 99.706%Color and Shape:SolidMolecular weight:530.57WH-4-023
CAS:WH-4-023 (Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK.Formula:C32H36N6O4Purity:98% - 99.75%Color and Shape:SolidMolecular weight:568.67Osimertinib
CAS:Osimertinib (AZD-9291) is a small molecule tyrosine kinase receptor inhibitor and antineoplastic agent that is used in the therapy of selected forms of NSCLC.Formula:C28H33N7O2Purity:99.32% - >99.99%Color and Shape:SolidMolecular weight:499.61Ref: TM-T2490
1g138.00€2g197.00€5g329.00€2mg34.00€5mg52.00€10mg55.00€25mg67.00€50mg80.00€100mg94.00€500mg114.00€1mL*10mM (DMSO)52.00€(E/Z)-Zotiraciclib citrate
(E/Z)-Zotiraciclib ((E/Z)-TG02) citrate is a potent inhibitor of CDK2, JAK2 and FLT3 and can be used in cancer research.Formula:C29H32N4O8Color and Shape:SolidMolecular weight:564.59eCF506
CAS:eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)Formula:C26H38N8O3Purity:97.85% - 98.16%Color and Shape:SolidMolecular weight:510.63XL019
CAS:XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.Formula:C25H28N6O2Purity:99.19%Color and Shape:SolidMolecular weight:444.53Ref: TM-T3072
2mg43.00€5mg63.00€10mg92.00€25mg150.00€50mg215.00€100mg321.00€200mg477.00€1mL*10mM (DMSO)78.00€Silymarin
CAS:Silymarin, a liver-aiding polyphenolic flavonoid, is extracted from milk thistle seeds.Formula:C25H22O10Purity:98%Color and Shape:Yellow And Brown PowderMolecular weight:482.441AD80
CAS:AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.Formula:C22H19F4N7OPurity:99.49% - 99.75%Color and Shape:SolidMolecular weight:473.43Ref: TM-T4301
1mg44.00€5mg96.00€10mg138.00€25mg268.00€50mg439.00€100mg645.00€500mg1,333.00€1mL*10mM (DMSO)90.00€4SC-203
CAS:4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.Formula:C33H38N8O4SPurity:99.52% - 99.84%Color and Shape:SolidMolecular weight:642.77(S)-Afatinib
CAS:(S)-Afatinib (BIBW2992) is an irreversible EGFR family inhibitor with IC50s of 0.5/0.4/10/14/1 nM for EGFRwt, L858R, L858R/T790M, HER2, and HER4, respectively.Formula:C24H25ClFN5O3Purity:99.22% - >99.99%Color and Shape:Off-White SolidMolecular weight:485.94CP-380736
CAS:CP-380736 (PF-00520893) inhibits EGFR, a kinase key in cancer-signaling pathways like MAPK, JNK, and Akt.Formula:C14H18N2O5Purity:99.68%Color and Shape:White To Off-White SolidMolecular weight:294.3NSC 228155
CAS:NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.Formula:C11H6N4O4SPurity:99.84%Color and Shape:SolidMolecular weight:290.25Ref: TM-T6908
2mg34.00€5mg48.00€10mg63.00€25mg117.00€50mg178.00€100mg334.00€200mg469.00€1mL*10mM (DMSO)50.00€OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formula:C22H16F3N3O2SPurity:99.67%Color and Shape:SolidMolecular weight:443.44Theliatinib
CAS:Theliatinib: potent, selective EGFR inhibitor, anti-tumor; Ki=0.05 nM (EGFR), IC50=3 nM (EGFR), 22 nM (T790M/L858R).Formula:C25H26N6O2Purity:99.67%Color and Shape:SolidMolecular weight:442.51GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Formula:C21H23N7O2S·HClPurity:99.87%Color and Shape:SolidMolecular weight:473.98Lorlatinib
CAS:Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogeneFormula:C21H19FN6O2Purity:99.77% - 99.95%Color and Shape:SolidMolecular weight:406.41Ref: TM-T3061
1mg34.00€2mg42.00€5mg60.00€10mg89.00€25mg137.00€50mg212.00€100mg374.00€1mL*10mM (DMSO)66.00€A-176120
CAS:A-176120: potent FPP analog, inhibits farnesyltransferase, anti-angiogenic, may curb H-ras NIH3T3 tumor growth.Formula:C33H29NO9Color and Shape:SolidMolecular weight:583.58hVEGF-IN-1
CAS:hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.Formula:C34H43N7O2Purity:99.76% - >99.99%Color and Shape:SolidMolecular weight:581.75EAI045
CAS:EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Formula:C19H14FN3O3SPurity:98.00% - 99.12%Color and Shape:SolidMolecular weight:383.4Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Formula:C25H21FN6O2SPurity:96.17% - 97.49%Color and Shape:SolidMolecular weight:488.54CZC-8004
CAS:CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formula:C17H16FN5Purity:99.29%Color and Shape:SolidMolecular weight:309.34KI8751
CAS:KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.Formula:C24H18F3N3O4Purity:99.22% - 99.9%Color and Shape:SolidMolecular weight:469.41Ref: TM-T2446
2mg34.00€5mg50.00€10mg81.00€25mg147.00€50mg279.00€100mg447.00€200mg635.00€1mL*10mM (DMSO)52.00€Sitravatinib
CAS:Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormula:C33H29F2N5O4SPurity:98.9% - 99.85%Color and Shape:SolidMolecular weight:629.68Ref: TM-T4349
5mg49.00€10mg74.00€25mg130.00€50mg200.00€100mg319.00€200mg507.00€500mg800.00€1mL*10mM (DMSO)69.00€R112
CAS:R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formula:C16H13FN4O2Purity:99.27% - 99.84%Color and Shape:SolidMolecular weight:312.3Ref: TM-T3185
1mg39.00€2mg51.00€5mg84.00€10mg124.00€25mg219.00€50mg329.00€100mg487.00€500mg1,026.00€1mL*10mM (DMSO)92.00€AC1NS4RE
CAS:It is a tyrosine kinase inhibitor.Formula:C15H13ClN2OPurity:99.53%Color and Shape:SolidMolecular weight:272.73CL-387785
CAS:CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.Formula:C18H13BrN4OPurity:99.56% - 99.62%Color and Shape:SolidMolecular weight:381.235-phenylthieno[2,3-d]pyrimidin-4-amine
CAS:5-phenylthieno[2,3-d]pyrimidin-4-amine is a heterocycle that inhibits enzymes like kinases, may treat diseases.Formula:C12H9N3SPurity:97%Color and Shape:SolidMolecular weight:227.29Ref: TM-T50042
2mg43.00€5mg60.00€10mg90.00€25mg138.00€50mg200.00€100mg301.00€200mg432.00€1mL*10mM (DMSO)60.00€BMS-2
CAS:BMS-2 is a Met/Flt-3/VEGFR2 tyrosine kinase inhibitor.Formula:C25H16F2N4O3Purity:98.33%Color and Shape:SolidMolecular weight:458.42Ref: TM-T8326
1mg67.00€2mg88.00€5mg148.00€10mg230.00€25mg430.00€50mg622.00€100mg898.00€1mL*10mM (DMSO)170.00€Arnebin 1
CAS:(Rac)-Arnebin 1 (beta, beta-dimethylacrylshikonin) has anti-tumor, anti-inflammatory, anti-immune deficiency and protecting liver.Formula:C21H22O6Purity:98.76% - 99.81%Color and Shape:SolidMolecular weight:370.40Ref: TM-T4586
1mg34.00€5mg67.00€10mg96.00€25mg138.00€50mg200.00€100mg294.00€200mg437.00€1mL*10mM (DMSO)74.00€Merestinib dihydrochloride
CAS:Merestinib dihydrochloride (LY2801653 dihydrochloride) is a kinase inhibitor with antitumor activity that inhibits MET and MKNK1/2.Formula:C30H24Cl2F2N6O3Color and Shape:SolidMolecular weight:625.45Tyrphostin B44, (+) enantiomer
CAS:Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)Formula:C18H16N2O3Purity:97.18%Color and Shape:SolidMolecular weight:308.33Ref: TM-T22450
1mg39.00€5mg82.00€10mg115.00€25mg192.00€50mg264.00€100mg380.00€200mg515.00€1mL*10mM (DMSO)90.00€URMC-099
CAS:URMC-099: oral, brain-accessible MLK/LRRK2 inhibitor; IC50 – MLK1/2/3/DLK: 19/42/14/150 nM, LRRK2: 11 nM.Formula:C27H27N5Purity:99.32% - 99.98%Color and Shape:SolidMolecular weight:421.54VEGFR-2-IN-5
CAS:VEGFR-2-IN-5 (UNC0064-12), multikinase inhibitor and has a -NH2 terminal linker for further synthesis.Formula:C19H24N8Purity:99.92%Color and Shape:SolidMolecular weight:364.45Ref: TM-T2056
1mg96.00€5mg235.00€10mg350.00€25mg590.00€50mg840.00€100mg1,130.00€1mL*10mM (DMSO)235.00€Syk Inhibitor II dihydrochloride
CAS:Syk inhibitor II selectively blocks Syk (IC50 = 41 nM), impacting platelet function and inflammation, with lower potency against other kinases.Formula:C14H17Cl2F3N6OPurity:98.53%Color and Shape:SolidMolecular weight:413.22Ref: TM-T4391
1mg130.00€2mg212.00€5mg455.00€10mg647.00€25mg947.00€50mg1,264.00€100mg1,700.00€1mL*10mM (DMSO)455.00€GluR6 antagonist-1
CAS:GluR6 antagonist-1 inhibits the pY binding site of tyrosine kinase p56lck SH2 domain.Formula:C15H11ClN2OSPurity:99.89%Color and Shape:SolidMolecular weight:302.78TAK-632
CAS:TAK-632 is a potent pan-Raf inhibitor.Formula:C27H18F4N4O3SPurity:98% - 99.5%Color and Shape:SolidMolecular weight:554.52Fisogatinib
CAS:Fisogatinib (BLU-554) is a highly potent, selective, and orally active FGFR4 inhibitor.Cost-effective and quality-assured.Formula:C24H24Cl2N4O4Purity:99.27% - ≥95%Color and Shape:SolidMolecular weight:503.38Ref: TM-T3456
1mg50.00€5mg114.00€10mg167.00€25mg294.00€50mg444.00€100mg670.00€500mg1,341.00€1mL*10mM (DMSO)127.00€ONO-4059 analog
CAS:ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.Formula:C25H24N6O3Purity:99.25%Color and Shape:SolidMolecular weight:456.5Ref: TM-T6921
1mg43.00€2mg56.00€5mg93.00€10mg137.00€25mg264.00€50mg439.00€100mg627.00€1mL*10mM (DMSO)90.00€Acalabrutinib
CAS:Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.Formula:C26H23N7O2Purity:98.94% - 99.64%Color and Shape:SolidMolecular weight:465.51Ref: TM-T3626
5mg44.00€10mg57.00€25mg78.00€50mg90.00€100mg144.00€200mg215.00€500mg355.00€1mL*10mM (DMSO)48.00€PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formula:C17H17N7Purity:98.45% - 99.93%Color and Shape:SolidMolecular weight:319.361-Naphthyl PP1
CAS:1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Formula:C19H19N5Purity:99.85%Color and Shape:White Cyrstalline SolidMolecular weight:317.39Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Formula:C28H30N6OSPurity:97.56% - >99.99%Color and Shape:SolidMolecular weight:498.64LDN-212854
CAS:LDN-212854 (BMP Inhibitor III), a novel BMP inhibitor, exhibits greater selectivity for BMP versus the TGF-β type I receptors.Formula:C25H22N6Purity:98% - 98.71%Color and Shape:SolidMolecular weight:406.48Ref: TM-T1900
1mg47.00€2mg62.00€5mg92.00€10mg172.00€25mg294.00€50mg439.00€100mg660.00€200mg945.00€1mL*10mM (DMSO)102.00€Gefitinib dihydrochloride
CAS:Gefitinib dihydrochloride: orally active, selective EGFR inhibitor (IC50: 33-54 nM), hinders tumor growth, induces autophagy and apoptosis in cancer research.Formula:C22H26Cl3FN4O3Color and Shape:SolidMolecular weight:519.82MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formula:C20H14Cl2FN5O2SPurity:97.6% - >99.99%Color and Shape:SolidMolecular weight:478.33Ref: TM-T4296
1mg60.00€2mg89.00€5mg167.00€10mg260.00€25mg439.00€50mg605.00€100mg802.00€200mg1,099.00€1mL*10mM (DMSO)170.00€Tivozanib
CAS:Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.Formula:C22H19ClN4O5Purity:98.08% - 99.67%Color and Shape:SolidMolecular weight:454.86Ref: TM-T2456
2mg38.00€5mg57.00€10mg79.00€25mg135.00€50mg226.00€100mg405.00€200mg597.00€1mL*10mM (DMSO)63.00€SUN11602
CAS:SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor.Formula:C26H37N5O2Purity:99.36%Color and Shape:SolidMolecular weight:451.6TAS6417
CAS:Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formula:C23H20N6OPurity:99.71%Color and Shape:SolidMolecular weight:396.44Ref: TM-T16996
1mg87.00€2mg124.00€5mg188.00€10mg311.00€25mg628.00€50mg838.00€100mg1,130.00€200mg1,549.00€1mL*10mM (DMSO)215.00€(E/Z)-Zotiraciclib
CAS:(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.Formula:C23H24N4OPurity:97.75% - 99.92%Color and Shape:SolidMolecular weight:372.46Ref: TM-T21503
1mg43.00€2mg56.00€5mg93.00€10mg113.00€25mg200.00€50mg330.00€100mg480.00€1mL*10mM (DMSO)90.00€SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Formula:C17H16N2O3Purity:98.91% - 99.64%Color and Shape:Yellow-Green SolidMolecular weight:296.32Quizartinib HCl
CAS:Quizartinib (AC220/AC010220) is an oral FLT3/STK1 inhibitor for treating AML, blocking kinase-driven cell proliferation and promoting apoptosis.Formula:C29H34Cl2N6O4SColor and Shape:SolidMolecular weight:633.59Adaphostin
CAS:Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.Formula:C24H27NO4Purity:98.29%Color and Shape:SolidMolecular weight:393.487BIO
CAS:7BIO triggers nonapoptotic death, blocks FLT3, DYRK1A/2, Aurora B/C kinases.
Formula:C16H10BrN3O2Purity:99.67%Color and Shape:SolidMolecular weight:356.17GSK1838705A
CAS:GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.Formula:C27H29FN8O3Purity:98.89% - >99.99%Color and Shape:SolidMolecular weight:532.571-Naphthyl PP1 hydrochloride
CAS:1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-SrcFormula:C19H20ClN5Purity:98.63%Color and Shape:SolidMolecular weight:353.85Momelotinib HCl
CAS:Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.Formula:C23H24Cl2N6O2Color and Shape:SolidMolecular weight:487.38(E)-AG 99
CAS:(E)-AG 99 ((E)-Tyrphostin AG 99) is an inhibitor of EGFR kinase (IC50: 10 μM in the human epidermoid carcinoma cell line A431).Formula:C10H8N2O3Purity:99.23%Color and Shape:SolidMolecular weight:204.185'-Fluoroindirubinoxime
CAS:5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).Formula:C16H10FN3O2Purity:>99.99%Color and Shape:SolidMolecular weight:295.27Olverembatinib dimesylate
CAS:Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).Formula:C29H27F3N6O·2CH4O3SPurity:97.66% - >99.99%Color and Shape:SolidMolecular weight:724.77Ref: TM-T2429
1mg37.00€5mg79.00€10mg113.00€25mg216.00€50mg289.00€100mg378.00€200mg552.00€1mL*10mM (DMSO)114.00€lavendustin C
CAS:lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formula:C14H13NO5Purity:98.06%Color and Shape:Yellow To Tan PowderMolecular weight:275.26Ref: TM-T4185
1mg42.00€2mg55.00€5mg93.00€10mg152.00€25mg330.00€50mg492.00€100mg707.00€1mL*10mM (DMSO)90.00€Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Formula:C24H27FN6O4Purity:99.82%Color and Shape:SolidMolecular weight:482.51Ruxolitinib phosphate
CAS:Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formula:C17H21N6O4PPurity:98% - >99.99%Color and Shape:SolidMolecular weight:404.36Ref: TM-T3043
1g583.00€5mg49.00€10mg62.00€25mg78.00€50mg92.00€100mg138.00€200mg215.00€500mg395.00€1mL*10mM (DMSO)56.00€Saracatinib
CAS:Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Formula:C27H32ClN5O5Purity:98% - 99.63%Color and Shape:SolidMolecular weight:542.03AZD-3463
CAS:AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.Formula:C24H25ClN6OPurity:99.13%Color and Shape:SolidMolecular weight:448.95SB-431542
CAS:SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.Formula:C22H16N4O3Purity:99.035% - >99.99%Color and Shape:SolidMolecular weight:384.39GDC-0214
CAS:GDC-0214 is an inhaled small-molecule JAK1 inhibitor and reduces fractional exhaled nitric oxide (Feno).Formula:C28H28ClF2N9O3Purity:99.75%Color and Shape:SolidMolecular weight:612.03Ref: TM-T9826
1mg93.00€5mg182.00€10mg269.00€25mg429.00€50mg610.00€100mg820.00€200mg1,099.00€1mL*10mM (DMSO)245.00€Tyrphostin A1
CAS:Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .Formula:C11H8N2OPurity:98.32%Color and Shape:SolidMolecular weight:184.19ODM-203
CAS:ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor ImmunityFormula:C26H21F2N5O2SPurity:99.85%Color and Shape:SolidMolecular weight:505.54PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Formula:C26H35Cl2N7OPurity:99.92%Color and Shape:SolidMolecular weight:532.51Ref: TM-T23127
1mg34.00€5mg96.00€10mg141.00€25mg289.00€50mg465.00€100mg662.00€200mg888.00€1mL*10mM (DMSO)118.00€Tranilast
CAS:Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment ofFormula:C18H17NO5Purity:99.67% - >99.99%Color and Shape:White With Light Yellow Crystalline PowderMolecular weight:327.33Ref: TM-T2690
5mg43.00€10mg55.00€25mg66.00€50mg93.00€100mg119.00€200mg175.00€500mg298.00€1mL*10mM (DMSO)55.00€Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFormula:C29H27F3N6OPurity:98% - 99.60%Color and Shape:SolidMolecular weight:532.56NVP-BSK805 trihydrochloride
CAS:NVP-BSK805 trihydrochloride inhibits JAK2 (0.48 nM IC50); also affects JAK1, JAK3, TYK2.Formula:C27H31Cl3F2N6OColor and Shape:SolidMolecular weight:599.93Zorifertinib
CAS:Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Formula:C22H23ClFN5O3Purity:98.20% - 99.36%Color and Shape:White To Off-White SolidMolecular weight:459.9Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purity:99.94% - >99.99%Color and Shape:SolidMolecular weight:266.29Ref: TM-T6711
2mg40.00€5mg58.00€10mg90.00€25mg180.00€50mg279.00€100mg411.00€200mg585.00€1mL*10mM (DMSO)81.00€PP2
CAS:PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Formula:C15H16ClN5Purity:98% - 98.21%Color and Shape:White SolidMolecular weight:301.77Ref: TM-T6266
2mg44.00€5mg65.00€10mg110.00€25mg178.00€50mg304.00€100mg482.00€200mg687.00€1mL*10mM (DMSO)71.00€SKLB4771
CAS:SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.Formula:C25H27N7O3S2Purity:98% - >99.99%Color and Shape:SolidMolecular weight:537.66Ref: TM-T2051
1mg63.00€2mg93.00€5mg124.00€10mg177.00€25mg371.00€50mg557.00€100mg792.00€500mg1,611.00€1mL*10mM (DMSO)148.00€WS6
CAS:WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.Formula:C29H31F3N6O3Purity:97.65% - 99.95%Color and Shape:SolidMolecular weight:568.59NVP-AEW541
CAS:NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-basedFormula:C27H29N5OPurity:98.7% - 99.86%Color and Shape:SolidMolecular weight:439.55(Z)-SU4312
CAS:(Z)-SU4312 is a inhibitor of MAO-B and NOS(IC50 value of 0.2 μM, 19.0μM,respectively).
Formula:C17H16N2OPurity:99.17%Color and Shape:SolidMolecular weight:264.32Lazertinib
CAS:Lazertinib (GNS-1480) is a potent, selective, irreversible EGFR-TKI; IC50: 1.7-76 nM for various EGFR mutations.Formula:C30H34N8O3Purity:98.7% - 99.90%Color and Shape:SolidMolecular weight:554.64Ref: TM-T4485
1mg46.00€2mg59.00€5mg96.00€10mg130.00€25mg215.00€50mg309.00€100mg444.00€200mg655.00€1mL*10mM (DMSO)104.00€ZM39923 hydrochloride
CAS:ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formula:C23H25NO·HClPurity:98.05%Color and Shape:SolidMolecular weight:367.91PD153035
CAS:PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR,Formula:C16H14BrN3O2Purity:98.47% - 99.29%Color and Shape:SolidMolecular weight:360.21SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFormula:C17H15NO2Purity:99.46%Color and Shape:SolidMolecular weight:265.31Mubritinib
CAS:Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.Formula:C25H23F3N4O2Purity:98.61% - 99.85%Color and Shape:SolidMolecular weight:468.47
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