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Angiogenesis

Angiogenesis

Angiogenesis inhibitors are compounds that interfere with the formation of new blood vessels, a process critical in cancer growth and metastasis. By inhibiting angiogenesis, these compounds can restrict the blood supply to tumors, slowing or halting their growth. Angiogenesis inhibitors are essential in cancer research and therapeutic development, providing insights into the mechanisms of tumor progression and offering potential treatments for cancer and other angiogenesis-related diseases. At CymitQuimica, we offer a wide range of high-quality angiogenesis inhibitors to support your research in oncology and vascular biology.

Subcategories of "Angiogenesis"

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Found 1414 products of "Angiogenesis"

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  • JI6

    CAS:
    <p>JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor.</p>
    Formula:C19H17N3O4S
    Purity:98.51%
    Color and Shape:Soild
    Molecular weight:383.42
  • ALK-IN-26

    CAS:
    <p>ALK-IN-26 is an ALK inhibitor with potential anticancer activity.ALK-IN-26 shows antiproliferative activity against glioblastoma.</p>
    Formula:C24H23NO3S
    Purity:99.91%
    Color and Shape:Soild
    Molecular weight:405.51
  • Icrucumab

    CAS:
    <p>Icrucumab, a humanized antibody, inhibits VEGFR-1 and shows antitumor effects, tested in metastatic colon cancer.</p>
    Purity:> 95%
    Color and Shape:Liquid
    Molecular weight:150 kDa
  • Ascrinvacumab

    CAS:
    <p>Ascrinvacumab (PF-03446962): humanized IgG2 anti-ALK-1 antibody, Kd 7 nM, inhibits TGF-β, for HCC research.</p>
    Purity:SDS-PAGE:95% SEC-HPLC:98.18%
    Color and Shape:Liquid
    Molecular weight:150 kDa
  • Gancotamab

    CAS:
    <p>Gancotamab (MM-302) is a polyethylene glycolated liposome targeting HER2 with antitumor activity for the study of advanced HER2-positive breast cancer.</p>
    Purity:96.7% (SDS-PAGE); 98.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 98.4% (SEC-HPLC)
    Color and Shape:Liquid
  • Petosemtamab

    CAS:
    <p>Petosemtamab (MCLA 158), a dual-action monoclonal antibody targets EGFR &amp; LGR5, used in solid tumor research like HNSCC &amp; CRC.</p>
    Purity:> 95% - > 95%
    Color and Shape:Liquid
    Molecular weight:145.97 kDa
  • SNIPER(ABL)-039

    CAS:
    <p>SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of</p>
    Formula:C54H68ClN11O9S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1114.77
  • EGFR-IN-162


    <p>EGFR-IN-162 (compound 20) is an effective EGFR inhibitor that enhances both early and late apoptosis (EGFR) as well as necrosis (necrosis). It shows potential for use in breast cancer research.</p>
    Formula:C27H31N3O2
    Color and Shape:Solid
    Molecular weight:429.24163
  • YH32367


    <p>YH32367 (ABL105) is a bispecific antibody targeting HER2 and 4-1BB. It induces the secretion of IFN-γ, resulting in the death of tumor cells when co-cultured with hPBMC and HER2-expressing tumor cells. YH32367 demonstrates notable antitumor activity.</p>
    Color and Shape:Odour Liquid
  • MPT0B390

    CAS:
    <p>MPT0B390 is an inhibitor of HDAC and a TIMP3 inducer inhibiting tumor growth, metastasis, and angiogenesis.</p>
    Formula:C17H17N3O5S
    Purity:99.4%
    Color and Shape:Solid
    Molecular weight:375.4
  • INCB-000928

    CAS:
    <p>Zilurgisertib (INCB-000928) is a selective and potent ALK 2 inhibitor for the study of cancer and MF anemia.</p>
    Formula:C30H38N4O3
    Purity:98.93%
    Color and Shape:Solid
    Molecular weight:502.65
  • Pomalidomide-C5-Dovitinib

    CAS:
    <p>Pomalidomide-C5-Dovitinib (compound 2) is a PROTAC that links Pomalidomide and Dovitinib via a CRBN connector, exhibiting potent antiproliferative activity in</p>
    Formula:C39H38FN9O6
    Purity:98%
    Color and Shape:Solid
    Molecular weight:747.77
  • JAK-IN-15

    CAS:
    <p>JAK-IN-15 is a JAK inhibitor. WO2016119700A1 (Compound 15).</p>
    Formula:C22H23FN4O3S
    Color and Shape:Solid
    Molecular weight:442.51
  • PF15 TFA


    <p>PF15 TFA, a PROTAC targeting FLT3 kinase and CRBN, exhibits selective degradation of FLT3-ITD with a DC50 of 76.7 nM.</p>
    Formula:C46H50F3N13O8
    Purity:98%
    Color and Shape:Solid
    Molecular weight:969.97
  • HIF-1 inhibitor-4

    CAS:
    <p>HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM.</p>
    Formula:C18H19IN2O2
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:422.26
  • HIF-1 Signaling Pathway Compound Library


    <p>A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies;</p>
    Color and Shape:Odour Solid
  • Angiogenesis related Compound Library


    <p>A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high</p>
    Color and Shape:Odour Solid
  • VEGFR-2-IN-64


    <p>VEGFR-2-IN-64 (Compound 28) is an inhibitor of VEGFR2 with an IC50 of 27.8 nM. It suppresses the proliferation of cancer cells A549, T-47D, and Caco-2, exhibits anti-migration and anti-colony formation activities in T-47D cells, and induces apoptosis in T-47D cells.</p>
    Formula:C72H123N9O6
    Color and Shape:Solid
    Molecular weight:1210.8
  • SNIPER(ABL)-015


    <p>SNIPER(ABL)-015, a compound that conjugates GNF5 (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 5</p>
    Formula:C58H70F3N9O9
    Purity:98%
    Color and Shape:Solid
    Molecular weight:1094.23
  • EGFR-IN-151


    <p>EGFR-IN-151 (Compound 10) inhibits EGFR and its downstream signaling pathways ERK/STAT3. It effectively suppresses the proliferation of various lung cancer cells, with IC50 values of 11.7, 5.19, 7.32, and 1.53 μM for NCI-H1781, HCC827, NCI-H3255, and NCI-H1975, respectively. Additionally, EGFR-IN-151 hinders colony formation and cell migration in H1975, induces G1 phase cell cycle arrest, and triggers apoptosis in H1975 cells.</p>
    Color and Shape:Odour Solid