Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5593 products of "Apoptosis"
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TJ08
CAS:<p>TJ08 has anticancer properties and can effectively induce G1/S phase blockade while promoting apoptosis in a variety of cancer cells.</p>Formula:C22H16FN3O4Purity:99.89%Color and Shape:SolidMolecular weight:405.38Didesmethylrocaglamide
CAS:<p>Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects,</p>Formula:C27H27NO7Color and Shape:SolidMolecular weight:477.51Semapimod
CAS:<p>Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6.</p>Formula:C34H52N18O2Color and Shape:SolidMolecular weight:744.9DC-CPin711
CAS:<p>DC-CPin711: Potent, selective CBP bromodomain inhibitor, IC50=0.0626 μM; arrests G1 cell cycle, induces apoptosis.</p>Formula:C23H22N4O2Color and Shape:SolidMolecular weight:386.45PI3K/AKT-IN-2
CAS:<p>PI3K/AKT-IN-2 inhibits PI3K/AKT, EMT, induces apoptosis, and blocks tubulin polymerization.</p>Formula:C32H27BrO10Color and Shape:SolidMolecular weight:651.45ROC-325
CAS:<p>ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.</p>Formula:C28H27ClN4OSPurity:99.26%Color and Shape:SolidMolecular weight:503.06VMY-1-103
CAS:<p>VMY-1-103: a strong CDK inhibitor better than purvalanol B; halts prostate/breast cancer cell growth, induces apoptosis, may treat medulloblastoma.</p>Formula:C34H42ClN9O4SColor and Shape:SolidMolecular weight:708.27PDK4-IN-1
CAS:<p>PDK4-IN-1 is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4)(IC50 value of 84 nM).</p>Formula:C22H19N3O2Purity:98%Color and Shape:SolidMolecular weight:357.41LLL3
CAS:<p>LLL3 is a small molecule STAT3 inhibitor.</p>Formula:C16H10O4Color and Shape:SolidMolecular weight:266.25W1131
CAS:<p>W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.</p>Formula:C23H19N5O4Color and Shape:SolidMolecular weight:429.43N1,N11-Diethylnorspermine
CAS:<p>DENSPM: potent anticancer, spurs polyamine breakdown, triggers cytochrome c release and caspase 3, kills GBM via SSAT & H2O2.</p>Formula:C13H32N4Color and Shape:SolidMolecular weight:244.42PS121912
CAS:<p>PS121912 is a potent and selective inhibitor of VDR-coactivator.</p>Formula:C24H21F3N2OPurity:98%Color and Shape:SolidMolecular weight:410.43DPQZ
CAS:<p>DPQZ is an anti-tubulin compound acting by inducing cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.</p>Formula:C20H17N3OPurity:98%Color and Shape:SolidMolecular weight:315.37SKLB70326
CAS:<p>SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.</p>Formula:C15H13N3O2SPurity:98%Color and Shape:SolidMolecular weight:299.35BMH-9
CAS:<p>BMH-9 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Formula:C19H27N3O2Color and Shape:SolidMolecular weight:329.44L 741742 (free base)
CAS:<p>L 741742 is an effective and highly selective antagonist of the D4 dopamine receptor (Ki: 1700, 770, and 3.5 nM at cloned human D2, D3, and D4 receptors).</p>Formula:C23H25ClN2OPurity:98%Color and Shape:SolidMolecular weight:380.91ALC67
CAS:<p>ALC67, a novel 3-propionyl thiazolidine-4-carboxylic acid ethyl ester, activates caspase-9, showing potent anticancer properties.</p>Formula:C15H15NO3SPurity:98%Color and Shape:SolidMolecular weight:289.35NSC-741909
CAS:<p>NSC-741909 is an anticancer agent that acts by suppressing the growth of several cell lines.</p>Formula:C16H14ClNOPurity:98%Color and Shape:SolidMolecular weight:271.74ATB-337
CAS:<p>S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.</p>Formula:C23H15Cl2NO2S3Color and Shape:SolidMolecular weight:504.47KF24345
CAS:<p>KF24345 is an inhibitor of adenosine uptake.</p>Formula:C31H38N6O5Color and Shape:SolidMolecular weight:574.67GRI977143
CAS:<p>GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.</p>Formula:C22H17NO4SPurity:98.07%Color and Shape:SolidMolecular weight:391.44D44
CAS:<p>D44 is a Plasmodium FKBPs inhibitor.</p>Formula:C16H16N4OSColor and Shape:SolidMolecular weight:312.39NKP-1339
CAS:<p>NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.</p>Formula:C14H12Cl4N4NaRuPurity:98%Color and Shape:SolidMolecular weight:502.14Flonoltinib
CAS:<p>Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.</p>Formula:C25H34FN7OPurity:99.52%Color and Shape:SolidMolecular weight:467.58BR102375
CAS:<p>BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.</p>Formula:C31H34N6O4Purity:98%Color and Shape:SolidMolecular weight:554.64GSK962
CAS:<p>GSK962 is a GSK963 inactive enantiomer. It can be used to confirm the on-target effects.</p>Formula:C14H18N2OPurity:99.75%Color and Shape:SolidMolecular weight:230.31Antitumor agent-44
CAS:<p>Antitumor agent-44 (Compound 5n) elicits potent antitumor effects by inducing disruption of mitochondrial homeostasis, cell cycle arrest, and apoptosis in human</p>Formula:C24H15N3O3Color and Shape:SolidMolecular weight:393.39APPA
CAS:<p>APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of</p>Formula:C14H13NO3Purity:98%Color and Shape:SolidMolecular weight:243.26NHI-2
CAS:<p>NHI-2 is an LDHA inhibitor (IC50 14.7 µM) that blocks glycolysis, induces apoptosis and cell cycle arrest, and suppresses tumor growth in melanoma models.</p>Formula:C17H12F3NO3Purity:99.981%Color and Shape:SolidMolecular weight:335.28MG-262
CAS:<p>MG-262 is a reversible proteasome inhibitor with multiple biological activities [1] [2] [3].</p>Formula:C25H42BN3O6Color and Shape:SolidMolecular weight:491.43M199
CAS:<p>M199, a novel inhibitor of TLR3/9 activation, induces secretion of IL-6, IL-8 and TNFalpha in human PBMCs.</p>Formula:C17H17N3OPurity:98%Color and Shape:SolidMolecular weight:279.34Polyphyllin II
CAS:<p>Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.</p>Formula:C44H70O16Purity:99.92%Color and Shape:SolidMolecular weight:855.02Mitochonic Acid 35
CAS:<p>Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.</p>Formula:C19H19NO5Purity:98%Color and Shape:SolidMolecular weight:341.36RET-IN-12
CAS:<p>RET-IN-12 is a RET inhibitor capable of acting on RET(WT) (IC50: 0.3 nM) and RET(V804M) (IC50: 1 nM).</p>Formula:C30H30F3N5O4Color and Shape:SolidMolecular weight:581.59PDE5/HDAC-IN-1
CAS:<p>PDE5/HDAC-IN-1 is a potent inhibitor of phosphodiesterase 5 (PDE5) and HDAC, with IC50 values of 46.3 nM and 14.5 nM, respectively.</p>Formula:C27H29BrN4O4Color and Shape:SolidMolecular weight:553.45Misetionamide
CAS:<p>Misetionamide: Oral oxathiazin-like, GAPDH inhibitor with anticancer properties for research use.</p>Formula:C3H7NO3SColor and Shape:SolidMolecular weight:137.16DC-5163
CAS:<p>DC-5163 inhibits GAPDH (IC50: 176.3 nM, Kd: 3.192 μM), targets cancer cell growth and glycolysis.</p>Formula:C18H20ClN3OSPurity:98%Color and Shape:SolidMolecular weight:361.89Cinnabarinic acid
CAS:<p>mGlu4 receptor agonist</p>Formula:C14H8N2O6Purity:98%Color and Shape:SolidMolecular weight:300.22Tezacitabine
CAS:<p>Tezacitabine, a nucleoside analogue, inhibits ribonucleotide reductase, disrupts DNA replication, and induces apoptosis in tumor cells.</p>Formula:C10H12FN3O4Color and Shape:SolidMolecular weight:257.22Apoptotic agent-2
CAS:<p>Apoptotic agent-2 reduces Bcl-2, boosts Bax & caspase-3, inducing apoptosis for cancer research.</p>Formula:C25H16ClN7SColor and Shape:SolidMolecular weight:481.96MMP-9-IN-4
CAS:<p>MMP-9-IN-4 inhibits MMP-9 (IC50=7.46nM) and AKT (IC50=8.82nM), induces apoptosis and is used in cancer research.</p>Formula:C28H19F3N4O6Color and Shape:SolidMolecular weight:564.47Topoisomerase II inhibitor 3
CAS:<p>Acridone-based Topoisomerase II inhibitor 3 targets topo IIα/β (IC50: 0.17μM α, 0.23μM β), causes DNA damage, and induces apoptosis.</p>Formula:C18H20N4O4Color and Shape:SolidMolecular weight:356.38NSC-639829
CAS:<p>NSC-639829 is an anti-tumor compound that requires a solubilizing agent for dissolution.</p>Formula:C21H20BrN5O3Purity:99.53% - 99.77%Color and Shape:SolidMolecular weight:470.32CEP-40125
CAS:<p>CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors.</p>Formula:C28H45Cl2N3O2Purity:98.28%Color and Shape:SolidMolecular weight:526.58AD-2646
CAS:<p>AD-2646 has antidepressant activity and inhibits 2-deoxy-D-glucose (2-DG)-induced gastric acid secretion.</p>Formula:C23H40N2O4Color and Shape:SolidMolecular weight:408.57CCT373567
CAS:<p>CCT373567 is a potent degrader of the transcriptional repressor BCL6 (IC50: 2.9 nM) and exhibits anti-proliferative effects.</p>Formula:C26H29ClF2N6O3Color and Shape:SolidMolecular weight:547Nampt-IN-3
CAS:<p>Nampt-IN-3 simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC (IC50s of 31 nM and 55 nM, respectively).</p>Formula:C29H25N7O2Purity:98%Color and Shape:SolidMolecular weight:503.55AZM475271
CAS:<p>AZM475271 is a potent and selective inhibitor of Src kinase(IC50 : 5 nM)</p>Formula:C23H27ClN4O3Purity:99.78%Color and Shape:SolidMolecular weight:442.94Anticancer agent 164
CAS:<p>CML-IN-1, also known as compound 7 and compound 4, is a potent anticancer agent that demonstrates a strong induced-apoptosis effect in the human chronic myeloid</p>Formula:C21H23F3N8O2S2Purity:98%Color and Shape:SolidMolecular weight:540.58Trehalose 6-behenate
CAS:<p>Trehalose 6-behenate is a Th1/Th17 skewing vaccine adjuvant.</p>Formula:C34H64O12Purity:98%Color and Shape:SolidMolecular weight:664.86Methylisothiazolinone
CAS:<p>Methylisothiazolinone (MI) is a powerful synthetic biocide and preservative within the group of isothiazolinones.</p>Formula:C4H5NOSPurity:99.78%Color and Shape:Colorless Prisms LiquidMolecular weight:115.15CMLD010509
CAS:<p>CMLD010509 (SDS-1-021) inhibits oncogenic proteins MDM2, CCND1, MYC, MAF, MCL-1 in multiple myeloma.</p>Formula:C27H26BrNO7Purity:98%Color and Shape:SolidMolecular weight:556.4Rooperol
CAS:<p>Rooperol: a norlignan with p38α inhibiting, immunomodulatory, antitumor, antibacterial, anticonvulsant, and antioxidant properties.</p>Formula:C17H14O4Purity:98%Color and Shape:SolidMolecular weight:282.29Topoisomerase I inhibitor 5
CAS:<p>Topoisomerase I inhibitor 5 halts DNA replication, induces MCF-7 cell apoptosis, and overcomes drug resistance. IC50 value is noted.</p>Formula:C24H24N2O2Color and Shape:SolidMolecular weight:372.46CMLD012073
CAS:<p>CMLD012073: Potent eIF4A inhibitor, halts eukaryotic translation; IC50 10 nM in NIH/3T3 cells.</p>Formula:C30H30N2O7Purity:98%Color and Shape:SolidMolecular weight:530.57RET-IN-22
CAS:<p>RET-IN-22 (compound 17b) is a potent, selective, and orally active inhibitor of RET, exhibiting IC50 values of 20.9 nM for wild-type RET and 18.3 nM for RET-</p>Formula:C29H31F3N6O4Color and Shape:SolidMolecular weight:584.59KRAS G12D inhibitor 14
CAS:<p>KRAS G12D inhibitor 14 is a potent inhibitor of KRAS G12D that binds KRAS G12D protein (Kd: 33 nM).</p>Formula:C20H19F3N4OSPurity:>99.99%Color and Shape:SolidMolecular weight:420.45S130
CAS:<p>S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.</p>Formula:C24H25N3O2Purity:98%Color and Shape:SolidMolecular weight:387.47Topoisomerase II inhibitor 9
CAS:<p>Topoisomerase II inhibitor 9: Topo II blocker (IC50: 0.97 μM), DNA intercalator (IC50: 43.51 μM), arrests G2/M in Hep G-2 cells and triggers apoptosis.</p>Formula:C22H17N7O3S2Color and Shape:SolidMolecular weight:491.55Antitumor agent-19
CAS:<p>Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.</p>Formula:C24H21ClF3N5OPurity:98.95% - 99.38%Color and Shape:SolidMolecular weight:487.9A-385358
CAS:<p>A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.</p>Formula:C32H41N5O5S2Purity:99.97%Color and Shape:SolidMolecular weight:639.83AZD-5991 Racemate
CAS:<p>AZD-5991 Racemate is the racemate of AZD-5991. (Rac)-AZD-5991 is a novel Mcl-1 inhibitor induces upregulation of BCL2,BCL-XL, CMYC and MCL1 in AML cell lines.</p>Formula:C35H34ClN5O3S2Color and Shape:SolidMolecular weight:672.26IM-54
CAS:<p>IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.</p>Formula:C19H23N3O2Purity:99.24%Color and Shape:SolidMolecular weight:325.4NSC260594
CAS:<p>NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-</p>Formula:C29H24N6O3Color and Shape:SolidMolecular weight:504.54PIK-C98
CAS:<p>PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.</p>Formula:C16H10Cl2N2OSPurity:98%Color and Shape:SolidMolecular weight:349.23Butyrolactone I
CAS:<p>Butyrolactone I (Olomoucin) inhibits CDKs, blocks cdc2 kinases, and shows antitumor activity in lung and prostate cancers.</p>Formula:C24H24O7Purity:98%Color and Shape:SolidMolecular weight:424.44Mcl1-IN-11
CAS:<p>Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.</p>Formula:C38H41N3O5S2Purity:98%Color and Shape:SolidMolecular weight:683.88AMG-548
CAS:<p>AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.</p>Formula:C29H27N5OPurity:99.91%Color and Shape:SolidMolecular weight:461.56A-802715
CAS:<p>A-802715 is a novel methylxanthine derivative that decreases the endogenous formation and blood levels of pro-inflammatory substances and increases the</p>Formula:C16H26N4O3Purity:96.29%Color and Shape:SolidMolecular weight:322.4AK301
CAS:<p>AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM).</p>Formula:C19H21ClN2O2Purity:99.27%Color and Shape:SolidMolecular weight:344.84GDP366
CAS:<p>GDP366, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. a dual inhibitor of survivin and Op18.</p>Formula:C20H17N5OSPurity:98.78% - 99.84%Color and Shape:SolidMolecular weight:375.45Tigilanol tiglate
CAS:<p>Tigilanol tiglate (EBC-46) is a PKC/C1 domain activator. Tigilanol tiglate induces immunogenic cell death and tumour regression.</p>Formula:C30H42O10Purity:98%Color and Shape:SolidMolecular weight:562.65Mcl1-IN-9
CAS:<p>Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.</p>Formula:C37H39ClN4O4Purity:98%Color and Shape:SolidMolecular weight:639.18LOM612
CAS:<p>LOM612 is a potent and specific FOXO relocator FOXO3a reporter protein endogenous FOXO3a and FOXO1 , down-regulates c-Myc and cyclin D1, anti-proliferative.</p>Formula:C13H10N2O2SColor and Shape:SolidMolecular weight:258.3SMIP004
CAS:<p>SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.</p>Formula:C13H19NOPurity:99.86%Color and Shape:SolidMolecular weight:205.3(5Z,2E)-CU-3
CAS:<p>(5Z,2E)-CU-3 is a potent and selective inhibitor of DGKα isozyme with an IC50 value of 0.6 μM and inhibition of DGKα by competing ATP with a Km value of 0.48 mM</p>Formula:C16H12N2O4S3Purity:99.02%Color and Shape:SolidMolecular weight:392.47USP7-IN-4
CAS:<p>USP7-IN-4 is a non-competitive, potent and selective inhibitor of USP7, up-regulates p53 and p21, down-regulates MDM2,anti-proliferativity RS4;11 (leukemia) .</p>Formula:C29H34N6O3Purity:98.27% - 99.09%Color and Shape:SolidMolecular weight:514.62Ac-IETD-CHO
CAS:<p>Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure.</p>Formula:C21H34N4O10Purity:98%Color and Shape:SolidMolecular weight:502.52Sparfosic Acid
CAS:<p>Sparfosic Acid (Acide sparfosique) is an aspartate carbamoyltransferase inhibitor with antitumor activity and can be used to study advanced renal cell carcinoma</p>Formula:C6H10NO8PPurity:98.89%Color and Shape:SolidMolecular weight:255.12MM-102
CAS:<p>MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.</p>Formula:C35H49F2N7O4Purity:98.77% - 99.99%Color and Shape:SolidMolecular weight:669.8ARP 101
CAS:<p>ARP 101 is a selective matrix metalloproteinase-2 (MMP-2) inhibitor with anticancer activity.</p>Formula:C20H26N2O5SPurity:98.26%Color and Shape:SolidMolecular weight:406.5ICG-001
CAS:<p>ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction.Cost-effective and quality-assured.</p>Formula:C33H32N4O4Purity:99.55% - 99.62%Color and Shape:SolidMolecular weight:548.63MK-886 sodium salt
CAS:<p>MK-886 sodium salt inhibits leukotriene biosynthesis in leukocytes.</p>Formula:C27H33ClNNaO2SColor and Shape:SolidMolecular weight:494.06CFM-5
CAS:<p>CFM-5 has anticonvulsant activity and is used in epilepsy research.</p>Formula:C23H18BrN3OSPurity:98%Color and Shape:SolidMolecular weight:464.38Fenoldopam hydrochloride
CAS:<p>Fenoldopam HCl: D1 dopamine receptor agonist, vasodilator, doesn't cross blood-brain barrier, α2-adrenoceptor antagonist.</p>Formula:C16H17Cl2NO3Color and Shape:SolidMolecular weight:342.22Ormeloxifene
CAS:estrogen receptor modulatorFormula:C30H35NO3Purity:98%Color and Shape:SolidMolecular weight:457.6IZTZ-1
CAS:<p>IZTZ-1: c-MYC G4 stabilizer, reduces expression, blocks cell cycle, induces apoptosis, inhibits B16 melanoma growth.</p>Formula:C32H35N7SColor and Shape:SolidMolecular weight:549.73MPT0B002
CAS:<p>MPT0B002 is a microtubule inhibitor that acts by downregulating T315I mutant Bcr-Abl and inducing apoptosis of imatinib-resistant chronic myeloid leukemia cells</p>Formula:C19H19NO4Purity:98%Color and Shape:SolidMolecular weight:325.36Tolbutamide Sodium
CAS:<p>potassium channel blocker</p>Formula:C12H18N2NaO3SPurity:98%Color and Shape:SolidMolecular weight:293.34cRIPGBM
CAS:<p>cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.</p>Formula:C26H20FN2O2Purity:98%Color and Shape:SolidMolecular weight:411.45NSC10010 hydrochloride
CAS:<p>NSC10010 inhibits gammaherpesvirus B-lymphomas by activating NF-κB and c-Myc pathways.</p>Formula:C31H42Cl2N4O2Purity:98%Color and Shape:SolidMolecular weight:573.60Glucocorticoid receptor modulator 1
CAS:<p>Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.</p>Formula:C24H23ClN2O4SPurity:99.79%Color and Shape:SolidMolecular weight:470.97Anti-inflammatory agent 54
CAS:<p>Anti-inflammatory agent 54 (compound 9c), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression</p>Formula:C17H16N2O5Color and Shape:SolidMolecular weight:328.32Thienopyridone
CAS:<p>Thienopyridone: potent, selective PRL phosphatase inhibitor, IC50s: 173/277/128 nM for PRL-1/2/3, induces apoptosis, anticancer.</p>Formula:C13H10N2OSPurity:98%Color and Shape:SolidMolecular weight:242.3PD-1/PD-L1-IN 6
CAS:<p>Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.</p>Formula:C25H26N2O3Color and Shape:SolidMolecular weight:402.49EGFR-IN-51
CAS:<p>EGFR-IN-51 effectively inhibits EGFR and mutations with IC50s of 0.493-461.63 μM; it induces apoptosis in cancer cells.</p>Formula:C21H15N3O2SColor and Shape:SolidMolecular weight:373.43CHMFL-ABL/KIT-155
CAS:<p>CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).</p>Formula:C33H38F3N5O3Purity:98%Color and Shape:SolidMolecular weight:609.68Tubulin polymerization-IN-26
CAS:<p>Tubulin-IN-26 blocks microtubule formation at colchicine site; IC50 4.64μM; may help in lung cancer study.</p>Formula:C25H23N3O2Color and Shape:SolidMolecular weight:397.47HDAC-IN-36
CAS:<p>HDAC-IN-36: Oral HDAC6 inhibitor, IC50 = 11.68 nM, promotes apoptosis & autophagy, anti-tumor & anti-metastatic, for breast cancer research.</p>Formula:C29H39N5O5Color and Shape:SolidMolecular weight:537.65Tubulin polymerization-IN-31
CAS:<p>Compound 4c, inhibits tubulin polymerization, IC50 3.64 μM, and induces cancer cell apoptosis.</p>Formula:C18H13ClFN3Color and Shape:SolidMolecular weight:325.77
