Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(6 products)
- BCL(11 products)
- Caspase(125 products)
- FOXO1(3 products)
- IAP(66 products)
- Mdm2(12 products)
- PD-1/PD-L1(125 products)
- PDK(9 products)
- PERK(25 products)
- Serine/threonin kinase(15 products)
- Survivin(13 products)
- TNF(92 products)
- c-RET(51 products)
- p53(62 products)
Show 6 more subcategories
Found 5592 products of "Apoptosis"
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CCT018159
CAS:<p>CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.</p>Formula:C20H20N2O4Purity:98.78% - 99.79%Color and Shape:SolidMolecular weight:352.38STAT3-IN-13
CAS:<p>STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.</p>Formula:C21H20N6O3SPurity:98.89%Color and Shape:SolidMolecular weight:436.49AMG PERK 44
CAS:<p>AMG PERK 44 is a PERK inhibitor that induces autophagy.AMG PERK 44 inhibits GCN2 and B-Raf and can be used in cancer research.</p>Formula:C34H29ClN4O2Purity:98.8% - 99.81%Color and Shape:SolidMolecular weight:561.07Minodronic acid
CAS:<p>Minodronic acid (YM-529) is a P2X2/3 antagonist with anticancer properties, inhibiting cell growth and metastasis, and used in osteoporosis research.</p>Formula:C9H12N2O7P2Purity:98.02%Color and Shape:SolidMolecular weight:322.15JY-2
CAS:<p>JY-2 is a forkhead transcription factor O1 (FoxO1) inhibitor with antidiabetic activity that inhibits FoxO1 transcription and can be used to study psoriasis.</p>Formula:C13H7Cl2N3OPurity:99.66%Color and Shape:SolidMolecular weight:292.12MJN68390
CAS:<p>MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.</p>Formula:C24H28ClN3O3Purity:98.86%Color and Shape:SolidMolecular weight:441.95EM-12
CAS:<p>EM-12, a Thalidomide analogue, is more active, stable, and boosts rat colon cancer studies.</p>Formula:C13H12N2O3Purity:99.34%Color and Shape:SolidMolecular weight:244.25Sarmustine
CAS:<p>SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K MGMT-transduced CD34(+) cells.</p>Formula:C6H11ClN4O3Purity:98.29% - 99.71%Color and Shape:SolidMolecular weight:222.63TL4-12
CAS:<p>TL4-12 is a MAP4K2 (GCK) inhibitor that inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation in vitro.</p>Formula:C25H27F3N6O2Purity:98.38%Color and Shape:SolidMolecular weight:500.52NLRP3/AIM2-IN-3
CAS:<p>NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.</p>Formula:C16H14N2O2Purity:97.04%Color and Shape:SolidMolecular weight:266.29TAI-1
CAS:<p>TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.</p>Formula:C24H21N3O3SPurity:99.58%Color and Shape:SolidMolecular weight:431.51DX3-213B
CAS:<p>DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM.</p>Formula:C20H28F2N2O5S2Purity:99.85%Color and Shape:SolidMolecular weight:478.57KR-33493
CAS:<p>KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.</p>Formula:C20H18BrN3O3SPurity:99.96%Color and Shape:SolidMolecular weight:460.34Bomedemstat ditosylate
CAS:<p>Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.</p>Formula:C42H50FN7O8S2Purity:99.05%Color and Shape:SolidMolecular weight:864.02H2L5186303
CAS:<p>H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.</p>Formula:C26H20N2O8Purity:98.19%Color and Shape:SolidMolecular weight:488.45UC-112
CAS:<p>UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).</p>Formula:C22H24N2O2Purity:99.54%Color and Shape:SolidMolecular weight:348.44Brigimadlin
CAS:<p>Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.</p>Formula:C31H25Cl2FN4O3Purity:98.17%Color and Shape:SolidMolecular weight:591.46C6 Ceramide
CAS:<p>C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK.</p>Formula:C24H47NO3Purity:99.67%Color and Shape:SolidMolecular weight:397.63LCS3
CAS:<p>LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3</p>Formula:C11H7ClN2O4Purity:99.68%Color and Shape:SolidMolecular weight:266.64Tubulin inhibitor 11
CAS:<p>Potent, oral Tubulin inhibitor 11 hinders polymerization, targets Colchicine site, induces mitotic block, and apoptosis.</p>Formula:C22H23N3O3SPurity:98.32%Color and Shape:SoildMolecular weight:409.5CP 461
CAS:<p>CP 461 is a PDE2A inhibitor that promotes apoptosis in cancer cells without affecting normal cells or COX-1/2.</p>Formula:C25H22ClFN2OPurity:99.82%Color and Shape:SolidMolecular weight:420.91Pyrazoloacridine
CAS:<p>Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.</p>Formula:C19H21N5O3Purity:99.72%Color and Shape:SolidMolecular weight:367.4Cot inhibitor-1
CAS:<p>Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.</p>Formula:C27H27Cl2FN8Purity:98.59%Color and Shape:SolidMolecular weight:553.46RIPK3-IN-1
CAS:<p>RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.</p>Formula:C29H25FN4O4Purity:98.27%Color and Shape:SolidMolecular weight:512.53AZA1
CAS:<p>AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42.</p>Formula:C22H20N6Purity:99.75%Color and Shape:SolidMolecular weight:368.43Anticancer agent 110
CAS:<p>Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells</p>Formula:C18H13FN6OSPurity:98%Color and Shape:SolidMolecular weight:380.4OR-1896
CAS:<p>OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.</p>Formula:C13H15N3O2Purity:99.33%Color and Shape:SolidMolecular weight:245.28FA16
<p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>Formula:C22H27F3N4O2SPurity:99.44%Color and Shape:SolidMolecular weight:468.54HBDDE
CAS:<p>HBDDE inhibits PKCα/γ (IC50: 43/50 μM), favors them over PKCδ/βI/βII, and induces neuronal apoptosis. Derived from ellagic acid.</p>Formula:C16H18O8Purity:97.94%Color and Shape:SolidMolecular weight:338.31SPD304 dihydrochloride
CAS:<p>SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.</p>Formula:C32H34Cl2F3N3O2Purity:99.25%Color and Shape:SolidMolecular weight:620.53D609
CAS:<p>D609 (Tricyclodecan-9-yl-Xanthogenate) has antiviral and antiproliferative activities.D609 acts through competitive inhibition of PC, PC-P and SMS.</p>Formula:C11H15KOS2Purity:97.67% - 99.56%Color and Shape:Off-White PowderMolecular weight:266.46GSK-3β inhibitor 3
CAS:<p>GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3</p>Formula:C18H14FNO2SPurity:97.53%Color and Shape:SolidMolecular weight:327.37CSN5i-3
CAS:<p>CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5, as an anticancer agent.Cost-effective and quality-assured.</p>Formula:C28H29F2N5O2Purity:99.56% - >99.99%Color and Shape:SolidMolecular weight:505.56Sabizabulin
CAS:<p>Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.</p>Formula:C21H19N3O4Purity:98.10% - 99.79%Color and Shape:SolidMolecular weight:377.39EGFR-IN-11
CAS:<p>EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.</p>Formula:C29H35N9O2SPurity:99.93%Color and Shape:SolidMolecular weight:573.71AQ4
CAS:<p>AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.</p>Formula:C22H28N4O4Purity:96.28% - 97.15%Color and Shape:SolidMolecular weight:412.48UK-101
CAS:<p>UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM</p>Formula:C25H48N2O5SiPurity:99.08% - 99.25%Color and Shape:SolidMolecular weight:484.74iCRT-5
CAS:<p>iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity and can be used in the study of multiple myeloma.</p>Formula:C16H17NO5S2Purity:99.68%Color and Shape:SolidMolecular weight:367.44Atrosab
CAS:<p>Atrosab is a humanized IgG1 antibody targeting TNFR1, inhibiting TNF-mediated apoptosis, and can be used to study inflammatory and neurodegenerative diseases.</p>Purity:SDS-PAGE:>95%;SEC-HPLC:95.22%Color and Shape:LiquidMolecular weight:146.12 kDa1G244
CAS:<p>1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties.</p>Formula:C29H30F2N4O2Purity:99.14%Color and Shape:SolidMolecular weight:504.57SLMP53-1
CAS:<p>SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migration</p>Formula:C20H18N2O2Purity:99.64%Color and Shape:SolidMolecular weight:318.37LDCA
CAS:<p>LDCA inhibits LDH-A, disrupts mitochondrial function, induces apoptosis in cancer cells, and is non-toxic.</p>Formula:C8H5Cl3FNOPurity:98.99%Color and Shape:SolidMolecular weight:256.49SB 699551 dihydrochloride
CAS:<p>SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.</p>Formula:C34H47Cl2N3OPurity:99.83%Color and Shape:SolidMolecular weight:584.66GSK854
CAS:<p>GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.</p>Formula:C18H19ClN6O4S2Purity:98.79%Color and Shape:SolidMolecular weight:482.96GS-9191
CAS:<p>GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which</p>Formula:C37H51N8O6PPurity:98.01 - 99.28%Color and Shape:SolidMolecular weight:734.82BC 11 hydrobromide
CAS:<p>The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.</p>Formula:C8H12BBrN2O2SPurity:98.07%Color and Shape:SolidMolecular weight:290.97DCG066
CAS:<p>DCG066 is an inhibitor of lysine methyltransferase G9a with anticancer activity and may be used in the study of leukemia.</p>Formula:C30H31F6N3O2Purity:98.26% - 98.38%Color and Shape:SolidMolecular weight:579.58SYM 2081
CAS:<p>SYM 2081: Kainate receptor agonist, IC50 of 35 nM, depolarizes muscle, lowers EPSP amplitude.</p>Formula:C6H11NO4Purity:99.59%Color and Shape:SolidMolecular weight:161.16LQZ-7F
CAS:<p>LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.</p>Formula:C14H7N9O3Purity:98.64%Color and Shape:SolidMolecular weight:349.26MBM-55
CAS:<p>MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.</p>Formula:C28H27FN6O2Purity:99.83%Color and Shape:SolidMolecular weight:498.55MMRi64
CAS:<p>MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.</p>Formula:C22H17Cl2N3OPurity:99.93%Color and Shape:SolidMolecular weight:410.3Antifolate C2
CAS:<p>Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.</p>Formula:C19H21N5O6SPurity:99.57%Color and Shape:SolidMolecular weight:447.46BCP-T.A
CAS:<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Formula:C23H19Cl2N3OSPurity:99.49%Color and Shape:SolidMolecular weight:456.39VAS 3947
CAS:<p>VAS 3947: NOX inhibitor, induces platelet apoptosis via UPR, not linked to NOX inhibition.</p>Formula:C14H10N6OSPurity:98.44%Color and Shape:SolidMolecular weight:310.33Mepazine
CAS:<p>Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.</p>Formula:C19H22N2SPurity:99.88% - 99.92%Color and Shape:SolidMolecular weight:310.46RS1-PDK1 inhibitor
CAS:<p>RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.</p>Formula:C15H9ClN2O2S3Purity:98.12%Color and Shape:SolidMolecular weight:380.89EB1
CAS:<p>EB1 is an MNK kinase inhibitor that inhibits cancer cell growth, promotes apoptosis, and inhibits eIF4E phosphorylation.</p>Formula:C18H14N4Purity:99.82%Color and Shape:SolidMolecular weight:286.33NecroX-7
CAS:<p>NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.</p>Formula:C24H29N3O3SPurity:98.22%Color and Shape:SolidMolecular weight:439.57Mitazalimab
CAS:<p>Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.</p>Purity:95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Color and Shape:LiquidStemazole
CAS:<p>Stemazole activates human stem cell growth, boosts survival, reduces cell death, and aids myelin repair, with therapeutic potential in demyelinating diseases.</p>Formula:C9H9N5OS2Purity:98.57%Color and Shape:SolidMolecular weight:267.33Vamotinib
CAS:<p>Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.</p>Formula:C29H27F3N6OPurity:99.64%Color and Shape:SolidMolecular weight:532.56CMLD-2
CAS:<p>CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.</p>Formula:C31H31NO6Purity:99.99%Color and Shape:SolidMolecular weight:513.58NM-3
CAS:<p>NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.</p>Formula:C13H12O6Purity:99.89%Color and Shape:SolidMolecular weight:264.23TC-DAPK 6
CAS:<p>TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.</p>Formula:C17H12N2O2Purity:98.73%Color and Shape:SolidMolecular weight:276.29Dasatinib hydrochloride
CAS:<p>Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).</p>Formula:C22H27Cl2N7O2SPurity:99.88% - 99.98%Color and Shape:SolidMolecular weight:524.47CUDC-427
CAS:<p>CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.</p>Formula:C29H36N6O4SPurity:99.92%Color and Shape:SolidMolecular weight:564.7Prinomastat
CAS:<p>Prinomastat: orally active, crosses blood-brain barrier, inhibits MMP-1/2/3/9, Ki/IC50s: 0.05-0.3/5.0-79 nM, antitumor.</p>Formula:C18H21N3O5S2Purity:99.23%Color and Shape:SolidMolecular weight:423.51N6-Cyclopentyladenosine
CAS:<p>N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's of</p>Formula:C15H21N5O4Purity:99.84%Color and Shape:SolidMolecular weight:335.36GSK2593074A
CAS:<p>GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.</p>Formula:C27H23N5OSPurity:99.76%Color and Shape:SolidMolecular weight:465.57UCB-5307
CAS:<p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>Formula:C22H21N3OPurity:98.76%Color and Shape:SolidMolecular weight:343.42Triparanol
CAS:<p>Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1</p>Formula:C27H32ClNO2Purity:99.72%Color and Shape:SolidMolecular weight:438Lanperisone HCl
CAS:<p>Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.</p>Formula:C15H19ClF3NOPurity:98.67% - >99.99%Color and Shape:SolidMolecular weight:321.77TT01001
CAS:<p>TT01001, a mitoNEET agonist, may treat type II diabetes by reducing oxidative stress and preventing neuronal death.</p>Formula:C15H19Cl2N3O2SPurity:99.93%Color and Shape:SolidMolecular weight:376.3eIF4A3-IN-1
CAS:<p>eIF4A3-IN-1 is an inhibitor of eukaryotic initiation factor 4A3 (eIF4A3). eIF4A3-IN-1 inhibits cytosolic nonsense-mediated RNA decay at high concentrations.</p>Formula:C29H23BrClN5O2Purity:99.49% - 99.89%Color and Shape:SolidMolecular weight:588.88CTA 056
CAS:<p>CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.</p>Formula:C35H34N6OPurity:97.22% - 97.76%Color and Shape:SolidMolecular weight:554.68GCN2-IN-1
CAS:<p>GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.</p>Formula:C19H18N10OPurity:99.49% - 99.64%Color and Shape:SolidMolecular weight:402.41RO-5963
CAS:<p>RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).</p>Formula:C24H21ClF2N4O5Purity:99.28%Color and Shape:SolidMolecular weight:518.9Ro 90-7501
CAS:<p>Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.</p>Formula:C20H16N6Purity:97.21% - 99.72%Color and Shape:SolidMolecular weight:340.38Cipepofol
CAS:<p>HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.</p>Formula:C14H20OPurity:99.77%Color and Shape:SolidMolecular weight:204.31A09-003
CAS:<p>A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.</p>Formula:C23H26N4OPurity:99.61%Color and Shape:SolidMolecular weight:374.48Perphenazine dihydrochloride
CAS:<p>Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.</p>Formula:C21H28Cl3N3OSPurity:99.67%Color and Shape:SolidMolecular weight:476.89HS38
CAS:<p>HS38: DAPK-specific ATP-competitive inhibitor; Kds: DAPK1 (300 nM), PIM3 (200 nM), ZIPK (280 nM); useful in smooth muscle disorder research.</p>Formula:C14H12ClN5O2SPurity:98.19%Color and Shape:SolidMolecular weight:349.8K-8012
CAS:<p>K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.</p>Formula:C23H23FN4Purity:99.72%Color and Shape:SolidMolecular weight:374.45p53-MDM2-IN-1
CAS:<p>p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM.</p>Formula:C23H20ClN3O3Purity:99.98%Color and Shape:SoildMolecular weight:421.88Exisulind
CAS:<p>Exisulind (CP248) triggers apoptosis via PKG activation, shows antitumor effects, and inhibits growth in various rodent cancer models.</p>Formula:C20H17FO4SPurity:97.94%Color and Shape:SolidMolecular weight:372.41Alethine
CAS:<p>Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.</p>Formula:C10H22N4O2S2Purity:98.83%Color and Shape:SolidMolecular weight:294.44Ciglitazone
CAS:<p>Ciglitazone: potent PPARγ agonist, EC50 3 μM, oral hypoglycemic; reduces insulin, blood pressure, Th17 cells, VEGF; halts gastric cancer growth.</p>Formula:C18H23NO3SPurity:98.23% - 99.59%Color and Shape:White Cyrstalline SolidMolecular weight:333.45Triciribine phosphate
CAS:<p>Triciribine phosphate (VD 002) is an AKT inhibitor that inhibits neovascularization and can be used in the study of leukemia.</p>Formula:C13H17N6O7PPurity:97.94%Color and Shape:SolidMolecular weight:400.28Gallium maltolate
CAS:<p>Gallium maltolate is a ribonucleoside-diphosphate reductase inhibitor.</p>Formula:C18H15GaO9Purity:99.61% - 99.67%Color and Shape:SolidMolecular weight:445.03CCT020312
CAS:<p>CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.</p>Formula:C31H30Br2N4O2Purity:98.63%Color and Shape:SolidMolecular weight:650.4W146
CAS:<p>W146 is an S1PR1 antagonist that induces a significant but transient decrease in blood lymphocytes in mice.</p>Formula:C16H27N2O4PPurity:99.37%Color and Shape:SolidMolecular weight:342.37TNIK-IN-3
CAS:<p>TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).</p>Formula:C23H18FN3O2Purity:98.39%Color and Shape:SolidMolecular weight:387.41CBS9106
CAS:<p>CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.</p>Formula:C18H21ClF3N3O3Purity:98.98%Color and Shape:SolidMolecular weight:419.83DB1976
CAS:<p>DB1976: Selenophene DB270 analog, inhibits PU.1 (IC50=10 nM), disrupts PU.1/DNA (KD=12 nM), induces apoptosis, cell-permeable.</p>Formula:C20H16N8SePurity:98.74%Color and Shape:SolidMolecular weight:447.35Etomoxir
CAS:<p>Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a) (IC50=5-20 nM), inhibits fatty acid oxidation. High-Quality, Low-Cost!</p>Formula:C17H23ClO4Purity:98% - 99.39%Color and Shape:SolidMolecular weight:326.82cRIPGBM chloride
CAS:<p>cRIPGBM chloride is a pro-apoptotic derivative found in GBM cancer stem cells with anti-tumor activity, inducing caspase-1-dependent apoptosis.</p>Formula:C26H20ClFN2O2Purity:99.75%Color and Shape:SolidMolecular weight:446.9SCFSkp2-IN-2
CAS:<p>SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.</p>Formula:C17H20N4O2Purity:99.86%Color and Shape:SolidMolecular weight:312.37UNC0321
CAS:<p>UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.</p>Formula:C27H45N7O3Purity:99.80%Color and Shape:SolidMolecular weight:515.69Apostatin-1
CAS:<p>Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.</p>Formula:C19H27N3OSPurity:99.31%Color and Shape:SolidMolecular weight:345.5Ro24-7429
CAS:<p>Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.</p>Formula:C14H13ClN4Purity:99.29% - 99.85%Color and Shape:SolidMolecular weight:272.73
