Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
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Antitumor agent-115
CAS:Antitumor agent-115 (SS-12) is a potent anti-tumor compound, exhibiting an IC50 range of 0.34 μM-24.14 μM against the 4T1 mouse breast cancer cell line.Formula:C19H38ClNO2Purity:98%Color and Shape:SolidMolecular weight:347.96Telomerase-IN-5
CAS:Telomerase-IN-5 is a potent inhibitor of telomerase with antiproliferative properties, and it induces apoptosis [1].Formula:C22H20N4OS2Purity:98%Color and Shape:SolidMolecular weight:420.55Antitumor agent-83
Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.Formula:C29H30N6O2Color and Shape:SolidMolecular weight:494.59PHA-690509
CAS:PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.Formula:C17H21N3O2SPurity:98%Color and Shape:SolidMolecular weight:331.43Dipin
CAS:Dipin is an Antineoplastic.Formula:C12H24N6O2P2Purity:98%Color and Shape:SolidMolecular weight:346.31PDE5-IN-3
CAS:PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.Formula:C21H14BrN5O2Color and Shape:SolidMolecular weight:448.27Topoisomerase I inhibitor 2
CAS:ZML-8 selectively inhibits Top1, blocks G2/M phase, causes DNA damage, and induces apoptosis with anti-tumor properties.Formula:C18H15NO3Color and Shape:SolidMolecular weight:293.32Prinomastat hydrochloride
CAS:Prinomastat HCl, an oral MMP (1, 3, 9) inhibitor, IC50s: 79, 6.3, 5.0 nM, shows antitumor activity.
Formula:C18H22ClN3O5S2Purity:98%Color and Shape:SolidMolecular weight:459.97PI3Kα-IN-6
CAS:PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor that exhibits anticancer effects without toxicity to normal cells.Formula:C16H15IN2OSColor and Shape:SolidMolecular weight:410.27Oxythiamine chloride HCl
CAS:Oxythiamine chloride is a thiamine antagonist and anticancer agent that inhibits transketolase, affecting RNA/DNA synthesis and inducing apoptosis.Formula:C12H17Cl2N3O2SColor and Shape:SolidMolecular weight:338.25Esuberaprost Sodium
CAS:Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.Formula:C23H27FN4O2Color and Shape:SolidMolecular weight:410.48Vin-C01
CAS:Vin-C01, a potent protector of pancreatic β-cells (EC50=0.22μM), aids in type 2 diabetes research by preventing STZ-induced β-cell apoptosis.Formula:C20H24N2OColor and Shape:SolidMolecular weight:308.42Epofolate
CAS:Epofolate: folate receptor-targeted antimitotic, delivers epothilone to cancer cells, inhibits mitosis, may halt tumor growth. Check clinical trials.Formula:C67H92N16O22S3Color and Shape:SolidMolecular weight:1569.74Mcl1-IN-3
CAS:Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.Formula:C27H22ClN3O4Purity:98%Color and Shape:SolidMolecular weight:487.93Antiproliferative agent-7
CAS:Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.Formula:C28H32N4OColor and Shape:SolidMolecular weight:440.58S-Gem
CAS:S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.Formula:C13H15F2N3O6S2Purity:98%Color and Shape:SolidMolecular weight:411.4p-nitro-Pifithrin-α
CAS:p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor.Formula:C15H16BrN3O3SColor and Shape:SolidMolecular weight:398.27MI-63
CAS:MI-63 is a potent, specific, non-peptide inhibitor of the MDM2-p53 interaction.Formula:C29H35Cl2FN4O3Color and Shape:SolidMolecular weight:577.52Anticancer agent 72
CAS:Compound 8c inhibits K+ channel and induces apoptosis, showing promise as an anticancer agent.Formula:C20H19N7O2Color and Shape:SolidMolecular weight:389.41SKLB0565
CAS:SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.Formula:C20H25ClN6OColor and Shape:SolidMolecular weight:400.91CEP-1612
CAS:CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.Formula:C35H53N7O7Color and Shape:SolidMolecular weight:683.84SIRT6 activator 12q
CAS:SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.Formula:C31H22N2O2Color and Shape:SolidMolecular weight:454.52BLM-IN-2
BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.Formula:C33H38BrFN4OColor and Shape:SolidMolecular weight:605.58TRK-IN-23
CAS:TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,Formula:C20H17FN4O2Purity:98%Color and Shape:SolidMolecular weight:364.37NSC114792
CAS:NSC114792 is a selective JAK3 inhibitor.Formula:C26H32N4O2SPurity:98%Color and Shape:SolidMolecular weight:464.62DMH2
CAS:DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.Formula:C27H25N5O2Purity:98%Color and Shape:SolidMolecular weight:451.52DBIBB
CAS:DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.Formula:C23H20N2O6SPurity:98.49% - 99.1%Color and Shape:SolidMolecular weight:452.48Ref: TM-T22070
1mg42.00€5mg93.00€10mg134.00€25mg264.00€50mg378.00€100mg553.00€500mg1,111.00€1mL*10mM (DMSO)93.00€Topoisomerase II inhibitor 10
CAS:Topoisomerase II inhibitor 10 is a potent inhibitor of topoisomerase II (IC50: 7.45 μM).Formula:C27H20N6O7SColor and Shape:SolidMolecular weight:572.55Alteminostat
CAS:Alteminostat is used as a histone deacetylase inhibitor and is an antineoplastic drug candidate.Formula:C27H36N6O3Color and Shape:SolidMolecular weight:492.61IDO1/TDO-IN-1
CAS:IDO1/TDO-IN-1 (30) inhibits IDO1 (Ki=0.23μM) & TDO (Ki=0.73μM); induces apoptosis via Bcl-2/Bax.Formula:C21H16O6Color and Shape:SolidMolecular weight:364.35TACC3 inhibitor 1
Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.Formula:C20H21N5OSColor and Shape:SolidMolecular weight:379.48EGFR-IN-60
CAS:EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.Formula:C28H28Cl2N6OColor and Shape:SolidMolecular weight:535.47PQ1 Succinate
CAS:PQ1 Succinate boosts GJIC and connexin in breast cancer cells without impacting normal mammary cells.Formula:C25H28F3N3O6Color and Shape:SolidMolecular weight:523.5HLI98C
CAS:HLI98C is a HDM2 ubiquitin ligase inhibitor with anti-tumor activity.Formula:C17H9ClN4O4Color and Shape:SolidMolecular weight:368.73Cl-amidine
CAS:Cl-amidine, an oral PAD inhibitor (IC50: 0.8-6.2 μM for PAD1/3/4), induces apoptosis in cancer cells.Formula:C14H19ClN4O2Purity:98%Color and Shape:SolidMolecular weight:310.78CDK/HDAC-IN-2
CAS:CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.Formula:C25H20Cl2N6O3Color and Shape:SolidMolecular weight:523.37ZT55
CAS:ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.Formula:C17H16N2O3Color and Shape:SolidMolecular weight:296.32Antioxidant agent-5
CAS:Antioxidant agent-5 (D-6) curbs oxLDL effects, ROS, NF-κB movement, apoptosis in VECs; boosts Nrf2/HO-1; protects endothelium.Formula:C24H24N6OColor and Shape:SolidMolecular weight:412.49IM-93
CAS:IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].Formula:C21H28N4O2Color and Shape:SolidMolecular weight:368.47LLP-3
CAS:Survivin inhibitor LLP-3 induces apoptosis in glioma cells by blocking Ran interaction; halts glioblastoma growth. IC50 = 31 μM.Formula:C32H23ClN2O4Color and Shape:SolidMolecular weight:534.99c-Met-IN-14
CAS:c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.Formula:C34H38ClFN4O7SColor and Shape:SolidMolecular weight:701.2Anticancer agent 83
CAS:Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.Formula:C20H19N5OSColor and Shape:SolidMolecular weight:377.46ZC0101
CAS:ZC0101: potent oral IDO1/TrxR inhibitor. IC50: 0.084/7.98 μM. Induces apoptosis, ROS in cancer cells.Formula:C17H15N3O2Color and Shape:SolidMolecular weight:293.32TH-Z835
CAS:TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 μM.Formula:C30H38N6OPurity:98%Color and Shape:SolidMolecular weight:498.66RO2468
CAS:RO2468 is a potent and orally active inhibitor of the p53-MDM2.Formula:C30H30Cl2FN5O4Purity:98%Color and Shape:SolidMolecular weight:614.49Quinidine polygalacturonate
CAS:Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.Formula:C26H34N2O9Color and Shape:SolidMolecular weight:518.22643Caylin-2
CAS:Nutlin-3 activates p53 by blocking MDM2. Caylin-2, a nutlin-3 analog with trifluoromethyl instead of chlorine, is 10x less potent with an 8 μM IC50.Formula:C32H30F6N4O4Color and Shape:SolidMolecular weight:648.6AV123
CAS:AV123, a RIPK1 inhibitor, non-cytotoxic, IC50: 12.12 μM; blocks TNF-α necroptosis (EC50: 1.7 μM) not apoptosis; useful in necrosis-related disease studies.Formula:C11H14N4O2Color and Shape:SolidMolecular weight:234.25Anti-inflammatory agent 22
CAS:Compound 14a is an oral anti-inflammatory with an IC50 of 14.6 μM for TNF-α, preventing adipogenesis and reducing mouse limb lymphedema.Formula:C22H16O6Color and Shape:SolidMolecular weight:376.36Bcl-2/Mcl-1-IN-2
CAS:Bcl-2/Mcl-1-IN-2 is a Bcl-2 (Ki: 4.70 μM) and Mcl-1 (Ki: 0.88 μM) inhibitor.Bcl-2/Mcl-1-IN-2 can be used in cancer research.Formula:C26H24ClNO3Color and Shape:SolidMolecular weight:433.93VO-OHPic
CAS:VO-OHPic, a selective PTEN inhibitor (IC50 = 46 nM), reduces apoptosis and inflammation in doxorubicin-induced cardiomyopathy.Formula:C12H10N2O8VColor and Shape:SolidMolecular weight:361.16MMP2-IN-1
CAS:MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.Formula:C15H13NO5SColor and Shape:SolidMolecular weight:319.33Cadein1
Cadein1, an isoquinolinium derivative, induces G2/M phase delay and caspase-dependent apoptosis in cancer cells lacking functional p53.Formula:C33H48F2INO2Color and Shape:SolidMolecular weight:655.64BMS-37
CAS:BMS-37 is a novel inhibitor of PD-1/PD-L1 immune checkpoint.Formula:C27H32N2O4Color and Shape:SolidMolecular weight:448.55GEM144
CAS:GEM144: oral POLA1/HDAC11 inhibitor; boosts p53, p21; halts G1/S cycle; triggers cell death.Formula:C28H31NO5Color and Shape:SolidMolecular weight:461.55ATSP-7041
CAS:ATSP-7041 is a novel potent and selective dual inhibitor of mdm2 (ki = 0.9 nm) and mdmx (ki = 7 nm)Formula:C87H125N17O21Color and Shape:SolidMolecular weight:1745.02PI3K/Akt/mTOR-IN-3
CAS:PI3K/Akt/mTOR-IN-3 is a powerful inhibitor, halting MCF-7, HeLa, and HepG2 cell migration and triggering S phase arrest and apoptosis.Formula:C34H51NO2Color and Shape:SolidMolecular weight:505.77BI-0282
CAS:BI-0282 (Compound 1) is a potent inhibitor of the MDM2-p53 interaction.Formula:C30H23Cl2FN4O4Color and Shape:SolidMolecular weight:593.43Erbstatin
CAS:Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.Formula:C9H9NO3Color and Shape:SolidMolecular weight:179.17p53 Activator 5
CAS:Potent p53 Activator 5, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.Formula:C29H32F6N4OColor and Shape:SolidMolecular weight:566.58SAHA-OH
CAS:SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.Formula:C15H22N2O4Purity:98%Color and Shape:SolidMolecular weight:294.35Se-Methylselenocysteine hydrochloride
CAS:Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.Formula:C4H10ClNO2SePurity:98%Color and Shape:SolidMolecular weight:218.54(S)-PERK-IN-5
CAS:(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).Formula:C25H26F2N4O3Color and Shape:SolidMolecular weight:468.5PI3K inhibitor C 96
CAS:PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase. It shows effective activity against multiple myeloma in vitro and in vivo.Formula:C11H8N2O3SPurity:98%Color and Shape:SolidMolecular weight:248.26PD173952
CAS:PD173952 is a Src kinase and Myt1 inhibitor with antitumor activity, inhibits Lyn, Abl and Csk, and induces Bcr-Abl-dependent hematopoietic cell apoptosis.Formula:C24H21Cl2N5O2Purity:99.5%Color and Shape:SolidMolecular weight:482.36Anticancer agent 42
CAS:Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.Formula:C19H16Cl2N2O3Color and Shape:SolidMolecular weight:391.25Aurora kinase-IN-1
Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.Formula:C30H25Br2N3O5Color and Shape:SolidMolecular weight:667.34GGTI-2154
CAS:GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity againstFormula:C24H28N4O3Color and Shape:SolidMolecular weight:420.5RIPK1-IN-13
CAS:RIPK1-IN-13 inhibits RIPK1 (IC50=1139 nM), potentially blocking necrosis and treating inflammation.Formula:C21H20ClN3O3Color and Shape:SolidMolecular weight:397.85Bcl-2/Mcl-1-IN-3
CAS:Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.Formula:C27H26ClNO4Color and Shape:SolidMolecular weight:463.95ATX inhibitor 13
CAS:ATX inhibitor 13: orally active, IC50 3.4 nM, halts RAW264.7 cells at G2, curbs growth/migration, prompts apoptosis, suppresses tumors.Formula:C31H35Cl2N5O3Color and Shape:SolidMolecular weight:596.55Topoisomerase II inhibitor 7
CAS:Topoisomerase II inhibitor 7 halts cell division and induces apoptosis, targeting topoisomerase II alpha with a 3.19 μM IC50.Formula:C32H28BrN5O5SColor and Shape:SolidMolecular weight:674.56QTX125
CAS:QTX125: potent, selective HDAC6 inhibitor with strong antitumor effects.Formula:C23H19N3O5Color and Shape:SolidMolecular weight:417.41p53 Activator 2
CAS:p53 Activator 2 binds to DNA, breaks it, halts cell cycle at G2/M, triggers apoptosis, reduces Bcl-2/Bcl-xL, IC50: 1.73μM against MGC-803.Formula:C20H21N5O2Color and Shape:SolidMolecular weight:363.41BMS-566394
CAS:BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).Formula:C22H21F3N4O4Color and Shape:SolidMolecular weight:462.42TrxR inhibitor D9
CAS:TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).Formula:C25H20AuOPSColor and Shape:SolidMolecular weight:596.43K145
CAS:K145: Selective, oral SphK2 inhibitor, IC50 4.3 μM, Ki 6.4 μM, promotes cell apoptosis, strong antitumor effect, inactive against SphK1/other kinases.Formula:C18H24N2O3SPurity:98%Color and Shape:SolidMolecular weight:348.46CYD-2-11
CAS:CYD-2-11 is an effective and selective Bax agonist. It acts by targeting the structural pocket proximal to S184 in the C-terminal region of Bax.Formula:C22H18N2O3Color and Shape:SolidMolecular weight:358.39Anticancer agent 56
CAS:Anticancer agent 56 (4d) has potent action <3μM IC50 on various cancers, causing G2/M arrest and mitochondrial apoptosis via ROS and caspase activation.Formula:C20H18ClN3O3Color and Shape:SolidMolecular weight:383.83(S)-Erypoegin K
CAS:(S)-Erypoegin K is a potent anticancer agent that demonstrates strong anti-proliferative activity against HL-60 cells and induces apoptosis.Formula:C20H18O6Color and Shape:SolidMolecular weight:354.35Apoptotic agent-3
CAS:"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."Formula:C31H21N5OSColor and Shape:SolidMolecular weight:511.6CCT373566
CAS:CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.Formula:C26H29ClF2N6O3Color and Shape:SolidMolecular weight:547MR2938
CAS:MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.Formula:C21H24N4O3Color and Shape:SolidMolecular weight:380.44PD-1/PD-L1-IN-29
CAS:PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM.Formula:C26H24N2O6Color and Shape:SolidMolecular weight:460.48MPT0B214
CAS:MPT0B214, a potent microtubule inhibitor, disrupts tubulin polymerization and kills various cancer cells, including drug-resistant types.Formula:C20H20N2O5Color and Shape:SolidMolecular weight:368.38(Rac)-Indoximod
CAS:(Rac)-Indoximod, a robust IDO inhibitor, and IFN-γ combo reduce α-SMA hCM activity and boost apoptosis, aiding cardiac fibrosis.Formula:C12H14N2O2Color and Shape:SolidMolecular weight:218.25PI3Kδ-IN-11
CAS:PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.Formula:C27H21N5OColor and Shape:SolidMolecular weight:431.49YLT205
CAS:YLT205 is an inducer of apoptosis in human colorectal cells that acts by inhibiting tumor growth.Formula:C16H12BrClN4O2S2Purity:98%Color and Shape:SolidMolecular weight:471.78MDM2-p53-IN-16
CAS:MDM2-p53-IN-16 inhibits p53/MDM2 complex (IC 50 = 4.3 nM), triggers p53, causes GBM cell apoptosis, useful in cancer research.Formula:C32H33N3O5Color and Shape:SolidMolecular weight:539.62AMPK activator 11
CAS:AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-Formula:C25H20N4O2Purity:98%Color and Shape:SolidMolecular weight:408.45RGB-286147
CAS:RGB-286147 is a potent, selective, ATP-competitive Cdks inhibitor.Formula:C23H22Cl2N4O3Purity:98%Color and Shape:SolidMolecular weight:473.35CMC2.24
CAS:CMC2.24 inhibits Ras and ERK1/2, fights pancreatic tumors in mice, blocks MMPs (IC50: 2-69 µM), and reduces osteoarthritis by stabilizing cartilage.Formula:C26H21NO5Color and Shape:SolidMolecular weight:427.45EGFR-IN-88
CAS:EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosisFormula:C22H18Cl2N4O2SPurity:98%Color and Shape:SolidMolecular weight:473.37Antitumor agent-57
CAS:Antitumor agent-57 (Compound 3o) is a potent NQO1-directed antitumor compound.Formula:C20H15NO5Color and Shape:SolidMolecular weight:349.34VEGFR-2-IN-23
CAS:VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.Formula:C22H15N5O2Color and Shape:SolidMolecular weight:381.39Ferroptosis inducer-1
CAS:Ferroptosis inducer-1 is a Ferroptosis inducer with antitumor potential .Formula:C25H21ClN2O5Color and Shape:SolidMolecular weight:464.9Tubulin polymerization-IN-22
CAS:Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.Formula:C19H16O4Color and Shape:SolidMolecular weight:308.33NF-κB-IN-5
CAS:NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.Formula:C23H27N3O4Color and Shape:SolidMolecular weight:409.48AP23464
CAS:AP23464 inhibits Src/Abl kinases, effective on imatinib-resistant CML cells (IC50=14nM), blocks cell cycle, induces apoptosis, not against T315I mutant.Formula:C26H30N5O2PPurity:99.79%Color and Shape:SolidMolecular weight:475.52CZS-241
CZS-241: Oral PLK4 inhibitor (IC50=2.6 nM), less potent TRKA blocker (IC50=2.74 μM), triggers apoptosis and S/G2 arrest, anti-leukemia, safe for normal cells.Formula:C26H24ClF2N9OColor and Shape:SolidMolecular weight:551.98
