Apoptosis
Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.
Subcategories of "Apoptosis"
- ASK(9 products)
- BCL(1 products)
- Caspase(154 products)
- FOXO1(2 products)
- IAP(67 products)
- Mdm2(12 products)
- PD-1/PD-L1(126 products)
- PDK(9 products)
- PERK(23 products)
- Serine/threonin kinase(17 products)
- Survivin(14 products)
- TNF(91 products)
- c-RET(61 products)
- p53(63 products)
Show 6 more subcategories
Found 6170 products of "Apoptosis"
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LLP-3
CAS:Survivin inhibitor LLP-3 induces apoptosis in glioma cells by blocking Ran interaction; halts glioblastoma growth. IC50 = 31 μM.Formula:C32H23ClN2O4Color and Shape:SolidMolecular weight:534.99c-Met-IN-14
CAS:c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.Formula:C34H38ClFN4O7SColor and Shape:SolidMolecular weight:701.2Anticancer agent 83
CAS:Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.Formula:C20H19N5OSColor and Shape:SolidMolecular weight:377.46ZC0101
CAS:ZC0101: potent oral IDO1/TrxR inhibitor. IC50: 0.084/7.98 μM. Induces apoptosis, ROS in cancer cells.Formula:C17H15N3O2Color and Shape:SolidMolecular weight:293.32TH-Z835
CAS:TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 μM.Formula:C30H38N6OPurity:98%Color and Shape:SolidMolecular weight:498.66RO2468
CAS:RO2468 is a potent and orally active inhibitor of the p53-MDM2.Formula:C30H30Cl2FN5O4Purity:98%Color and Shape:SolidMolecular weight:614.49AV123
CAS:AV123, a RIPK1 inhibitor, non-cytotoxic, IC50: 12.12 μM; blocks TNF-α necroptosis (EC50: 1.7 μM) not apoptosis; useful in necrosis-related disease studies.Formula:C11H14N4O2Color and Shape:SolidMolecular weight:234.25Bcl-2/Mcl-1-IN-2
CAS:Bcl-2/Mcl-1-IN-2 is a Bcl-2 (Ki: 4.70 μM) and Mcl-1 (Ki: 0.88 μM) inhibitor.Bcl-2/Mcl-1-IN-2 can be used in cancer research.Formula:C26H24ClNO3Color and Shape:SolidMolecular weight:433.93MMP2-IN-1
CAS:MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.Formula:C15H13NO5SColor and Shape:SolidMolecular weight:319.33PI3K/Akt/mTOR-IN-3
CAS:PI3K/Akt/mTOR-IN-3 is a powerful inhibitor, halting MCF-7, HeLa, and HepG2 cell migration and triggering S phase arrest and apoptosis.Formula:C34H51NO2Color and Shape:SolidMolecular weight:505.77BI-0282
CAS:BI-0282 (Compound 1) is a potent inhibitor of the MDM2-p53 interaction.Formula:C30H23Cl2FN4O4Color and Shape:SolidMolecular weight:593.43Erbstatin
CAS:Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.Formula:C9H9NO3Color and Shape:SolidMolecular weight:179.17p53 Activator 5
CAS:Potent p53 Activator 5, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.Formula:C29H32F6N4OColor and Shape:SolidMolecular weight:566.58SAHA-OH
CAS:SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.Formula:C15H22N2O4Purity:98%Color and Shape:SolidMolecular weight:294.35Se-Methylselenocysteine hydrochloride
CAS:Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.Formula:C4H10ClNO2SePurity:98%Color and Shape:SolidMolecular weight:218.54(S)-PERK-IN-5
CAS:(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).Formula:C25H26F2N4O3Color and Shape:SolidMolecular weight:468.5Aurora kinase-IN-1
Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.Formula:C30H25Br2N3O5Color and Shape:SolidMolecular weight:667.34RIPK1-IN-13
CAS:RIPK1-IN-13 inhibits RIPK1 (IC50=1139 nM), potentially blocking necrosis and treating inflammation.Formula:C21H20ClN3O3Color and Shape:SolidMolecular weight:397.85p53 Activator 2
CAS:p53 Activator 2 binds to DNA, breaks it, halts cell cycle at G2/M, triggers apoptosis, reduces Bcl-2/Bcl-xL, IC50: 1.73μM against MGC-803.Formula:C20H21N5O2Color and Shape:SolidMolecular weight:363.41BMS-566394
CAS:BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).Formula:C22H21F3N4O4Color and Shape:SolidMolecular weight:462.42TrxR inhibitor D9
CAS:TrxR-IN-D9 is a novel inhibitor of thioredoxin reductase (TrxR).Formula:C25H20AuOPSColor and Shape:SolidMolecular weight:596.43K145
CAS:K145: Selective, oral SphK2 inhibitor, IC50 4.3 μM, Ki 6.4 μM, promotes cell apoptosis, strong antitumor effect, inactive against SphK1/other kinases.Formula:C18H24N2O3SPurity:98%Color and Shape:SolidMolecular weight:348.46CYD-2-11
CAS:CYD-2-11 is an effective and selective Bax agonist. It acts by targeting the structural pocket proximal to S184 in the C-terminal region of Bax.Formula:C22H18N2O3Color and Shape:SolidMolecular weight:358.39MR2938
CAS:MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.Formula:C21H24N4O3Color and Shape:SolidMolecular weight:380.44PD-1/PD-L1-IN-29
CAS:PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM.Formula:C26H24N2O6Color and Shape:SolidMolecular weight:460.48MPT0B214
CAS:MPT0B214, a potent microtubule inhibitor, disrupts tubulin polymerization and kills various cancer cells, including drug-resistant types.Formula:C20H20N2O5Color and Shape:SolidMolecular weight:368.38MDM2-p53-IN-16
CAS:MDM2-p53-IN-16 inhibits p53/MDM2 complex (IC 50 = 4.3 nM), triggers p53, causes GBM cell apoptosis, useful in cancer research.Formula:C32H33N3O5Color and Shape:SolidMolecular weight:539.62EGFR-IN-88
CAS:EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosisFormula:C22H18Cl2N4O2SPurity:98%Color and Shape:SolidMolecular weight:473.37VEGFR-2-IN-23
CAS:VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.Formula:C22H15N5O2Color and Shape:SolidMolecular weight:381.39Tubulin polymerization-IN-22
CAS:Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.
Formula:C19H16O4Color and Shape:SolidMolecular weight:308.33NF-κB-IN-5
CAS:NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.Formula:C23H27N3O4Color and Shape:SolidMolecular weight:409.48PD-1/PD-L1-IN-25
CAS:"PD-1/PD-L1-IN-25 blocks PD-1/PD-L1 (IC50: 16.17 nM), boosting T-cell anti-tumor immunity, useful for cancer research."Formula:C26H24ClN3O5Color and Shape:SolidMolecular weight:493.94GLS1 Inhibitor-4
CAS:GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.Formula:C29H27F3N10O2S2Purity:98%Color and Shape:SolidMolecular weight:668.72PDPOB
CAS:PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.Formula:C15H20O5Color and Shape:SolidMolecular weight:280.32PARP1-IN-10
CAS:PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.Formula:C20H23N3O5Color and Shape:SolidMolecular weight:385.41Nevanimibe
CAS:Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).Formula:C27H39N3OPurity:98%Color and Shape:SolidMolecular weight:421.62Anticancer agent 55
CAS:Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.Formula:C28H21Br2FN2O2Color and Shape:SolidMolecular weight:596.294HI5
CAS:HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, & triggers apoptosis.Formula:C42H43N5O8Color and Shape:SolidMolecular weight:745.82Obatoclax
CAS:Obatoclax (GX15-070), a pan-BCL-2 inhibitor (Ki 220 nM) induces autophagy, degrades cyclin D1, and has anti-cancer/antiparasitic properties.Formula:C20H19N3OPurity:99.44%Color and Shape:SolidMolecular weight:317.38JS-K
CAS:JS-K is a Nitric oxide donor. It has antiproliferative activity.Formula:C13H16N6O8Color and Shape:SolidMolecular weight:384.3HDAC-IN-51
HDAC-IN-51 is an HDAC inhibitor.Formula:C27H24N4O2Purity:98.85%Color and Shape:SolidMolecular weight:436.51MX107
CAS:MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.Formula:C24H28N2O2Color and Shape:SolidMolecular weight:376.49CT1-3
CAS:CT1-3 is a potent anti-cancer compound targeting JNK/Bcl-2 pathways, blocking EMT in HCCs, and is non-toxic to liver/kidneys in mice.Formula:C25H29NO3S2Color and Shape:SolidMolecular weight:455.63αβ-Tubulin-IN-1
CAS:αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.Formula:C25H19N3O3Color and Shape:SolidMolecular weight:409.44ZMF-10
CAS:ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.Formula:C19H17F6N7OColor and Shape:SolidMolecular weight:473.38MMP-9-IN-3
CAS:MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.Formula:C29H25N3O4Color and Shape:SolidMolecular weight:479.53PD-1/PD-L1-IN-20
CAS:PD-1/PD-L1-IN-20 is a small molecule inhibitor of PD-1/PD-L1 protein-protein interaction.Formula:C30H26BrClN2O3Color and Shape:SolidMolecular weight:577.9Undecylprodigiosin
CAS:Undecylprodigiosin is a classical cytotoxic immunosuppressant, suppressing immune functions. It also inhibits DNA synthesis.Formula:C25H35N3OColor and Shape:SolidMolecular weight:393.56JMX0293
JMX0293, a salicylamide derivative, inhibits STAT3, inducing MDA-MB-231 cell apoptosis with IC50=3.38μM, while sparing MCF-10A (IC50>60μM).Formula:C25H30Cl2N4O7Color and Shape:SolidMolecular weight:569.43Rohinitib
CAS:Rohinitib, an eIF4A inhibitor, triggers apoptosis in AML cells and lessens tumor load in models.Formula:C29H31NO8Color and Shape:SolidMolecular weight:521.56SCAL-255
CAS:SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM.Formula:C27H28F3N5O3Purity:98%Color and Shape:SolidMolecular weight:527.54ANO1-IN-3
CAS:ANO1-IN-3 (Compound 3n) can induces apoptosis that is a potent and selective inhibitor of ANO1 with an IC 50 of 1.23 μM [1].Formula:C20H17NO3Color and Shape:SolidMolecular weight:319.35NSC 107512
CAS:NSC 107512, a sangivamycin-like molecule, inhibits CDK9, curbing myeloma growth and triggering cell death.Formula:C12H16N6O5Color and Shape:SolidMolecular weight:324.29FAK-IN-5
CAS:FAK-IN-5 is a FAK signaling inhibitor that induces apoptosis and autophagy.Formula:C29H29ClF3N3O4Color and Shape:SolidMolecular weight:576.01BIBU-1361 dihydrochloride
CAS:BIBU-1361 dihydrochloride inhibits EGFR kinase, blocking MAPKK/MAPK activation.Formula:C22H29Cl3FN7Color and Shape:SolidMolecular weight:516.87p53 Activator 3
CAS:Potent p53 activator, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.Formula:C30H37F3N4O4SColor and Shape:SolidMolecular weight:606.7c-Fms-IN-12
CAS:c-Fms-IN-12 inhibits FMS/c-KIT, triggers A549 cell apoptosis, and has potential as a multi-cancer therapy.Formula:C30H32N6O6Color and Shape:SolidMolecular weight:572.61VEGFR-2-IN-22
CAS:VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.Formula:C26H24ClFN4O6Color and Shape:SolidMolecular weight:542.94IQDMA
CAS:IQDMA is an inhibitor of the transcription factor STAT5.Formula:C19H20N4Color and Shape:SolidMolecular weight:304.39Theophylline sodium glycinate
CAS:Theophylline sodium glycinate inhibits PDE3, treats asthma/COPD, blocks adenosine receptors, activates HDAC, reduces inflammation and induces apoptosis.Formula:C9H12N5NaO4Color and Shape:SolidMolecular weight:277.216Anticancer agent 50
CAS:Anticancer agent 50 targets ABCB1 pump, has cytotoxic effects, alters cyclin D1/p53, and shows promise in T lymphoma research.Formula:C30H32N2O4SeColor and Shape:SolidMolecular weight:563.55YC-137
CAS:YC-137 inhibits BCL-2, triggers apoptosis in Bcl-2-high cells, and blocks its anti-apoptotic function.Formula:C24H21N3O6S2Color and Shape:SolidMolecular weight:511.57STAT3-IN-10
CAS:STAT3-IN-10 (A11) inhibits STAT3; halts tumor growth and triggers apoptosis in cancer cells (IC 50 = 5.18 μM).Formula:C17H13NO5Color and Shape:SolidMolecular weight:311.29Bcl-2-IN-9
CAS:Bcl-2-IN-9: a novel, selective Bcl-2 inhibitor inducing apoptosis in leukemia with an IC50 of 2.9 μM; low cytotoxicity.Formula:C27H31N7O3SColor and Shape:SolidMolecular weight:533.65EGFR/BRAFV600E-IN-1
CAS:EGFR/BRAFV600E-IN-1 inhibits EGFR (0.08 μM) & BRAFV600E (0.15 μM), affects A-549, MCF-7, Panc-1 & HT-29 (IC50: 0.79-1.3 μM).Formula:C24H24ClN3O3Color and Shape:SolidMolecular weight:437.92MDM2/XIAP-IN-3
CAS:MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressingFormula:C29H30N2O5SColor and Shape:SolidMolecular weight:518.62DNA topoisomerase II inhibitor 1
CAS:Potent DNA topoisomerase II blocker; arrests cell cycle, induces apoptosis, anti-growth effects.Formula:C28H24N4O3SColor and Shape:SolidMolecular weight:496.58CS1
CAS:CS1: potent topoisomerase II alpha inhibitor, broad-spectrum antitumor, low toxicity, anti-resistance, induces DNA damage, G2/M arrest, apoptosis.Formula:C16H12O3Color and Shape:SolidMolecular weight:252.26Vin-F03
CAS:Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.Formula:C22H29N3Color and Shape:SolidMolecular weight:335.49CA224
CAS:CA224: selective oral Cdk4-cyclin D1 inhibitor, IC50=6.2μM, promotes apoptosis, has antitumor effects.Formula:C24H22N2OColor and Shape:SolidMolecular weight:354.44Antitumor agent-55
CAS:Antitumor agent-55 (5q) inhibits PC3 (IC50: 0.91 μM), blocks G1/S phase, induces apoptosis, and halts migration.Formula:C32H34N6O4SColor and Shape:SolidMolecular weight:598.72(rel)-Oxaliplatin
CAS:(rel)-Oxaliplatin, a DNA inhibitor, induces crosslinks, hinders replication/transcription, and triggers apoptosis; used in cancer studies.Formula:C8H14N2O4PtColor and Shape:SolidMolecular weight:397.29YM-155 hydrochloride
CAS:Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].Formula:C20H19ClN4O3Color and Shape:SolidMolecular weight:398.85PI3K/Akt/mTOR-IN-2
CAS:Potent PI3K/AKT/mTOR inhibitor, selective for MDA-MB-231 cells with IC50 of 2.29 μM; induces arrest and apoptosis.Formula:C17H13F2NOPurity:99.98%Color and Shape:SolidMolecular weight:285.29Ref: TM-T60564
1mg37.00€5mg79.00€10mg124.00€25mg255.00€50mg409.00€100mg602.00€500mg1,279.00€1mL*10mM (DMSO)87.00€Anti-inflammatory agent 55
CAS:Compound 9j (anti-inflammatory agent 55), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expressionFormula:C17H15N3O7Color and Shape:SolidMolecular weight:373.32Anti-inflammatory agent 15
CAS:Compound 29, anti-inflammatory and antimycobacterial, halts Mtb H37Rv and M299 growth; MIC50 at 2.3 and 7.8 μM. Blocks iNOS, TNF-α, IL-1β.Formula:C17H20N2SColor and Shape:SolidMolecular weight:284.42PDMP (hydrochloride)
CAS:PDMP, a glucosylceramide synthase inhibitor with 4 stereoisomers, acts at 0.8μM; D-threo enantiomer also blocks lactosylceramide synthesis.Formula:C23H39ClN2O3Color and Shape:SolidMolecular weight:427.03Apoptosis inducer 8
CAS:Apoptosis inducer 8 is a galectin-1 (gal-1)-mediated apoptosis inducer and a PET imaging agent that significantly reduces gal-1 protein levels and can be usedFormula:C29H22ClN5O2Color and Shape:SolidMolecular weight:507.97GY1-22
CAS:GY1-22, an inhibitor targeting the DNAJA1-mutP53 R175H interaction pocket, holds potential for cancer research applications.Formula:C23H20N4OSColor and Shape:SolidMolecular weight:400.5MDM2/XIAP-IN-2
CAS:MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP).Formula:C29H32N2O4SColor and Shape:SolidMolecular weight:504.64Pracinostat dihydrochloride
CAS:Pracinostat dihydrochloride is a highly effective histone deacetylase (HDAC) inhibitor with IC₅₀ values ranging from 40 to 140 nM, utilized in cancer research. Additionally, it inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) hydrolase activity with an EC₅₀ of less than 10 nM.Formula:C20H32Cl2N4O2Color and Shape:SolidMolecular weight:431.40STK17A/B-IN-1
CAS:STK17A/B-IN-1 (compound 9) is an orally active, potent, and selective inhibitor of STK17A/B, demonstrating an IC50 of 23 nM for STK17A. This compound is utilized in tumor research.Formula:C26H27N7OColor and Shape:SolidMolecular weight:453.54Ethacridine
CAS:Ethacridine acts as an inhibitor of poly (ADP-ribose) glycohydrolase (PARG) and functions as an activator of transcriptional coactivators. It induces apoptosis in thyroid cancer cells and promotes the differentiation of thyroid follicular cells.Formula:C15H15N3OColor and Shape:SolidMolecular weight:253.30RIPK1-IN-12
CAS:RIPK1-IN-12: Strong RIPK1 blocker, hinders necroptosis; EC50=1.6 nM (human), 2.9 nM (mouse).Formula:C24H26N4O3SColor and Shape:SolidMolecular weight:450.55NPD4928
CAS:NPD4928 boosts cancer cell sensitivity to GPX4 inhibitors, hinting at therapeutic potential through ferroptosis.Formula:C29H32N2O6Color and Shape:SolidMolecular weight:504.57Mitoguazone
CAS:Mitoguazone is an antitumor agent, blocking SAM decarboxylase, disrupting polyamine synthesis, and hindering HIV DNA integration in immune cells.Formula:C5H12N8Purity:97.47% - 98%Color and Shape:SolidMolecular weight:184.2Lemuteporfin
CAS:Lemuteporfin is a light-activated photosensitizing agent confers cytotoxic upon light activation.reduce sebaceous gland volume in animal studies.Formula:C44H48N4O10Purity:97.14% - 99.44%Color and Shape:SolidMolecular weight:792.87R-8507
CAS:R-8507: TNF-αRI antagonist, blocks ICAM-1, halts receptor complex internalization, EC50: 2.45 μM (TNF-α), 3.79 μM (IL-1β).Formula:C16H8ClF3N4Color and Shape:SolidMolecular weight:348.71PARP1-IN-31
CAS:PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC₅₀ of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549).Formula:C22H15ClFN3O2Purity:98.99%Color and Shape:SolidMolecular weight:407.83Ozarelix
CAS:Ozarelix: a GnRH antagonist that induces apoptosis in advanced prostate cancer, modulates death receptors, and reduces sex hormones.Formula:C72H96ClN17O14Color and Shape:SolidMolecular weight:1459.09ATAD2-IN-1
CAS:ATAD2-IN-1 (compound 19f) serves as a potent ATAD2 inhibitor (IC 50: 0.27 μM), capable of inducing apoptosis. Additionally, it suppresses c-Myc activation and impedes the migration of BT-549 cells [1].Formula:C22H26N6O5Color and Shape:SolidMolecular weight:454.48IDH1 Inhibitor 9
CAS:IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.Formula:C26H30N4O3Color and Shape:SolidMolecular weight:446.54α-NETA
CAS:α-NETA is a ChA inhibitor and an ALDH1A1 and CMKLR1 antagonist with anticancer activity and inhibits cholinesterase and acetylcholinesterase (AChE).Formula:C16H20INOPurity:99.54%Color and Shape:SolidMolecular weight:369.24A 410099.1
CAS:A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.Formula:C27H41ClN4O3Purity:99.30%Color and Shape:SolidMolecular weight:505.1IDT
CAS:IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.Formula:C8H5NS2Purity:98%Color and Shape:SolidMolecular weight:179.26PS121912
CAS:PS121912 is a potent and selective inhibitor of VDR-coactivator.Formula:C24H21F3N2OPurity:98%Color and Shape:SolidMolecular weight:410.43DPQZ
CAS:DPQZ is an anti-tubulin compound acting by inducing cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.Formula:C20H17N3OPurity:98%Color and Shape:SolidMolecular weight:315.37SKLB70326
CAS:SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.Formula:C15H13N3O2SPurity:98%Color and Shape:SolidMolecular weight:299.35WK-298
CAS:WK-298 is an effective MDM2/MDMX-p53 interaction inhibitor.Formula:C35H38Cl2N6OPurity:98%Color and Shape:SolidMolecular weight:629.62NSC-741909
CAS:NSC-741909 is an anticancer agent that acts by suppressing the growth of several cell lines.Formula:C16H14ClNOPurity:98%Color and Shape:SolidMolecular weight:271.74
