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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 6039 products of "Apoptosis"

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  • bpV(phen)
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    bpV(phen)

    CAS:
    bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).
    Formula:C12H8KN2O5V
    Purity:98%
    Color and Shape:Solid
    Molecular weight:350.24

    Ref: TM-T10594

  • RIPK1-IN-13
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    RIPK1-IN-13

    CAS:
    RIPK1-IN-13 inhibits RIPK1 (IC50=1139 nM), potentially blocking necrosis and treating inflammation.
    Formula:C21H20ClN3O3
    Color and Shape:Solid
    Molecular weight:397.85

    Ref: TM-T61887

  • RO27-3225 TFA
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    RO27-3225 TFA

    CAS:
    RO27-3225, a MC4R agonist (EC50=1nM), may treat obesity and brain damage, also acts on MC1R, and helps in hemorrhagic shock.
    Formula:C41H53F3N12O8
    Color and Shape:Solid
    Molecular weight:898.9462

    Ref: TM-T70838

  • RIPK3-IN-2
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    RIPK3-IN-2

    CAS:
    RIPK3-IN-2 is a RIP3 inhibitor that can be used in studies of diseases caused by or associated with activated necrotic pathways.
    Formula:C21H16ClN3O2S2
    Color and Shape:Solid
    Molecular weight:441.95

    Ref: TM-T62569

  • IM-54
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    IM-54

    CAS:
    <p>IM-54 is a cell-permeable, effective, and selective necrosis inhibitor.</p>
    Formula:C19H23N3O2
    Purity:99.24%
    Color and Shape:Solid
    Molecular weight:325.4

    Ref: TM-T24160

  • Antiproliferative agent-19
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    Antiproliferative agent-19

    Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.
    Formula:C26H23NO
    Color and Shape:Solid
    Molecular weight:365.47

    Ref: TM-T72205

  • DB2313 HCl
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    DB2313 HCl

    CAS:
    DB2313: first-in-class, potent inhibitor of PU.1, disrupts gene interactions, down-regulates PU.1 targets.
    Formula:C42H45Cl4FN8O2
    Color and Shape:Solid
    Molecular weight:854.67

    Ref: TM-T69842

  • NSC260594
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    NSC260594

    CAS:
    NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-
    Formula:C29H24N6O3
    Color and Shape:Solid
    Molecular weight:504.54

    Ref: TM-T78579

  • MIR002
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    MIR002

    CAS:
    MIR002: an oral POLA1/HDAC11 inhibitor with antitumor effects, enhances p53/p21, causes G1/S arrest, and triggers apoptosis.
    Formula:C27H29NO5
    Color and Shape:Solid
    Molecular weight:447.52

    Ref: TM-T62917

  • MI-192
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    MI-192

    CAS:
    MI-192: Selective HDAC2/3 inhibitor, IC50=30/16 nM, induces apoptosis in myeloid leukemia, potential in leukemia/anti-stroke treatment.
    Formula:C24H21N3O2
    Color and Shape:Solid
    Molecular weight:383.44

    Ref: TM-T21898

  • Aurora kinase-IN-1
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    Aurora kinase-IN-1

    Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.
    Formula:C30H25Br2N3O5
    Color and Shape:Solid
    Molecular weight:667.34

    Ref: TM-T72522

  • NPD4928
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    NPD4928

    CAS:
    NPD4928 boosts cancer cell sensitivity to GPX4 inhibitors, hinting at therapeutic potential through ferroptosis.
    Formula:C29H32N2O6
    Color and Shape:Solid
    Molecular weight:504.57

    Ref: TM-T68239

  • Tubulin/MMP-IN-2
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    Tubulin/MMP-IN-2

    CAS:
    Tubulin/MMP-IN-2 blocks tubulin polymerization, MMP-2/-3/-9, induces apoptosis, aids cancer research, IC50: 24.95, 31.60, 22.37 µM.
    Formula:C40H48NO11P
    Color and Shape:Solid
    Molecular weight:749.78

    Ref: TM-T72719

  • EGFR/BRAFV600E-IN-1
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    EGFR/BRAFV600E-IN-1

    CAS:
    EGFR/BRAFV600E-IN-1 inhibits EGFR (0.08 μM) & BRAFV600E (0.15 μM), affects A-549, MCF-7, Panc-1 & HT-29 (IC50: 0.79-1.3 μM).
    Formula:C24H24ClN3O3
    Color and Shape:Solid
    Molecular weight:437.92

    Ref: TM-T62503

  • TPB15
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    TPB15

    CAS:
    TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.
    Formula:C18H9Cl4N5O
    Color and Shape:Solid
    Molecular weight:453.11

    Ref: TM-T62772

  • Estramustine phosphate
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    Estramustine phosphate

    CAS:
    <p>Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties.</p>
    Formula:C23H32Cl2NO6P
    Color and Shape:Solid
    Molecular weight:520.38

    Ref: TM-T4451L

  • DRI-C25441
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    DRI-C25441

    CAS:
    DRI-C25441 is a potent inhibitor of the CD40-CD40L interaction, exhibiting an IC50 value of 0.36 μM, and is capable of suppressing the immune response triggered
    Formula:C31H21N3O6
    Color and Shape:Solid
    Molecular weight:531.51

    Ref: TM-T79194

  • Prexasertib mesylate
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    Prexasertib mesylate

    CAS:
    Prexasertib (LY2606368), a Chk1/2 inhibitor, enhances therapy in acute lymphoblastic leukemia, causing DNA damage and antitumor effects.
    Formula:C19H23N7O5S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:461.49

    Ref: TM-T4310L2

  • EGFR-IN-52
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    EGFR-IN-52

    CAS:
    EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.
    Formula:C19H18N4O3S
    Color and Shape:Solid
    Molecular weight:382.44

    Ref: TM-T61646

  • ZINC69391
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    ZINC69391

    CAS:
    <p>ZINC69391 inhibits Rac1, reduces cancer cell growth and metastasis, and induces apoptosis.</p>
    Formula:C14H14F3N5
    Purity:99.61%
    Color and Shape:Solid
    Molecular weight:309.29

    Ref: TM-T24833