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Apoptosis

Apoptosis

Apoptosis inhibitors are compounds that prevent or delay the process of programmed cell death, known as apoptosis. These inhibitors are vital in studying cell survival mechanisms and are used to investigate diseases where apoptosis is dysregulated, such as cancer, neurodegenerative disorders, and autoimmune diseases. By modulating apoptosis, these inhibitors can help in the development of therapies aimed at controlling cell death. At CymitQuimica, we provide a comprehensive selection of high-quality apoptosis inhibitors to support your research in cell biology, oncology, and related fields.

Subcategories of "Apoptosis"

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Found 6039 products of "Apoptosis"

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  • Obatoclax

    CAS:
    Obatoclax (GX15-070), a pan-BCL-2 inhibitor (Ki 220 nM) induces autophagy, degrades cyclin D1, and has anti-cancer/antiparasitic properties.
    Formula:C20H19N3O
    Purity:99.44%
    Color and Shape:Solid
    Molecular weight:317.38
  • PDMP (hydrochloride)

    CAS:
    PDMP, a glucosylceramide synthase inhibitor with 4 stereoisomers, acts at 0.8μM; D-threo enantiomer also blocks lactosylceramide synthesis.
    Formula:C23H39ClN2O3
    Color and Shape:Solid
    Molecular weight:427.03
  • STAT3-IN-11

    CAS:
    STAT3-IN-11 is a STAT3 inhibitor.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.
    Formula:C20H17NO4
    Purity:98.3%
    Color and Shape:Solid
    Molecular weight:335.35
  • Anti-inflammatory agent 15

    CAS:
    Compound 29, anti-inflammatory and antimycobacterial, halts Mtb H37Rv and M299 growth; MIC50 at 2.3 and 7.8 μM. Blocks iNOS, TNF-α, IL-1β.
    Formula:C17H20N2S
    Color and Shape:Solid
    Molecular weight:284.42
  • L6H21

    CAS:
    L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.
    Formula:C18H18O4
    Purity:99.26%
    Color and Shape:Solid
    Molecular weight:298.33
  • ISC-4

    CAS:
    ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.
    Formula:C11H13NSe
    Color and Shape:Solid
    Molecular weight:238.19
  • PDE5-IN-3

    CAS:
    PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.
    Formula:C21H14BrN5O2
    Color and Shape:Solid
    Molecular weight:448.27
  • Bisindolylmaleimide VIII

    CAS:
    <p>Bisindolylmaleimide VIII (Ro-31-7549) is a selective and highly potent protein kinase C (PKC) inhibitor.</p>
    Formula:C24H22N4O2
    Purity:97% - 98.01%
    Color and Shape:Solid
    Molecular weight:398.46
  • JS-K

    CAS:
    JS-K is a Nitric oxide donor. It has antiproliferative activity.
    Formula:C13H16N6O8
    Color and Shape:Solid
    Molecular weight:384.3
  • HDAC-IN-42

    CAS:
    HDAC-IN-42, a potent HDAC inhibitor: IC50 - 0.19μM (HDAC1), 4.98μM (HDAC6); halts cancer cell growth, triggers apoptosis & G2/M arrest.
    Formula:C20H15NO7
    Color and Shape:Solid
    Molecular weight:381.34
  • HDAC-IN-51


    HDAC-IN-51 is an HDAC inhibitor.
    Formula:C27H24N4O2
    Purity:98.85%
    Color and Shape:Solid
    Molecular weight:436.51
  • Anti-inflammatory agent 55

    CAS:
    Compound 9j (anti-inflammatory agent 55), a Coixol derivative, exhibits anti-inflammatory properties by inhibiting the NF-κB pathway and reducing the expression
    Formula:C17H15N3O7
    Color and Shape:Solid
    Molecular weight:373.32
  • MX107

    CAS:
    MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.
    Formula:C24H28N2O2
    Color and Shape:Solid
    Molecular weight:376.49
  • CEP-40125

    CAS:
    CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors.
    Formula:C28H45Cl2N3O2
    Purity:98.28%
    Color and Shape:Solid
    Molecular weight:526.58
  • PI3K/Akt/mTOR-IN-2

    CAS:
    Potent PI3K/AKT/mTOR inhibitor, selective for MDA-MB-231 cells with IC50 of 2.29 μM; induces arrest and apoptosis.
    Formula:C17H13F2NO
    Purity:99.98%
    Color and Shape:Solid
    Molecular weight:285.29
  • LWG-301


    LWG-301, a GLS1 allosteric inhibitor, IC50 7 nM, impedes glutamine metabolism and prompts apoptosis; shows antitumor effects.
    Formula:C28H38N8O3S
    Color and Shape:Solid
    Molecular weight:566.72
  • Antitumor agent-55

    CAS:
    Antitumor agent-55 (5q) inhibits PC3 (IC50: 0.91 μM), blocks G1/S phase, induces apoptosis, and halts migration.
    Formula:C32H34N6O4S
    Color and Shape:Solid
    Molecular weight:598.72
  • CA224

    CAS:
    CA224: selective oral Cdk4-cyclin D1 inhibitor, IC50=6.2μM, promotes apoptosis, has antitumor effects.
    Formula:C24H22N2O
    Color and Shape:Solid
    Molecular weight:354.44
  • Topoisomerase I inhibitor 2

    CAS:
    ZML-8 selectively inhibits Top1, blocks G2/M phase, causes DNA damage, and induces apoptosis with anti-tumor properties.
    Formula:C18H15NO3
    Color and Shape:Solid
    Molecular weight:293.32
  • Vin-F03

    CAS:
    Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.
    Formula:C22H29N3
    Color and Shape:Solid
    Molecular weight:335.49